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AI Podcasts

December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Strategic Implication: The next frontier in AI is agentic, and progress hinges on fundamental pre-training innovation, not just post-training optimizations.
  2. Builder/Investor Note: Focus on teams with deep experience in scaling and debugging large models, as this is a high-capital, high-risk endeavor. Builders should prioritize developing new benchmarks for agentic capabilities.
  3. The "So What?": The industry needs to move beyond next-token prediction and static benchmarks to unlock truly capable, self-correcting AI agents in the next 6-12 months.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Shift in AI Development: The focus moves from syntax-aware code generation to execution-aware reasoning, enabling more robust and intelligent code agents.
  2. Builder/Investor Note: Prioritize tools and platforms that support explicit execution modeling and highly asynchronous, high-throughput RL training for agentic systems.
  3. The "So What?": AI that can simulate complex systems internally will drastically reduce development and testing costs, accelerating innovation in software and distributed systems over the next 6-12 months.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Strategic Shift: AI-driven kernel generation is not replacing human genius but augmenting it, allowing experts to focus on novel breakthroughs while AI automates the application of known optimizations across a complex hardware landscape.
  2. Builder/Investor Note: Focus on robust validation and hardware-in-the-loop systems. Claims of "AI inventing new algorithms" in this domain are premature. The real value is in automating the "bag of tricks" for heterogeneous compute.
  3. The "So What?": This technology is critical for scaling agentic AI workloads. Expect significant investment in tools that abstract hardware complexity and enable efficient, automated optimization, driving down the cost of AI inference in the next 6-12 months.
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December 18, 2025

AI Consulting in Practice – NLW, Super ai

AI Engineer

AI
Key Takeaways:
  1. The Agent Economy is Here: Enterprises are moving past pilots with AI agents. Builders should focus on orchestration layers and human-agent interaction design.
  2. ROI Measurement is the Next Frontier: Investors should look for solutions that help organizations accurately track and attribute AI value beyond traditional metrics.
  3. Strategic AI, Not Spot Solutions: The biggest wins come from systematic, cross-organizational AI strategies that target new capabilities and revenue growth, not just incremental time savings.
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December 18, 2025

How to build an AI native company (even if your company is 50 years old) – Dan Shipper, Every

AI Engineer

AI
Key Takeaways:
  1. The 100% AI adoption threshold is a step-function change, not incremental. Companies that commit fully will outpace those with partial integration.
  2. Builders should prioritize "compounding engineering" by codifying knowledge into reusable prompts. This builds an organizational memory that accelerates future development exponentially.
  3. Re-evaluate team structures and roles. Single engineers can own complex products, and even technical managers can contribute code, shifting how organizations operate.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. Effective crime reduction requires a shift from reactive punishment to proactive, intelligence-driven deterrence, making it highly probable for criminals to be caught.
  2. The market for AI-powered public safety technology, particularly solutions that integrate data for precision and accountability, presents a significant opportunity. Public-private partnerships are a key funding mechanism.
  3. Over the next 6-12 months, expect to see more cities adopt advanced surveillance and AI tools, driven by private funding, as they seek to improve safety and address staffing shortages without resorting to ineffective, broad-stroke policies.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade will be defined by who builds the core infrastructure for intelligence. This is where the most significant value and influence will accrue.
  2. Builder/Investor Note: Direct capital and talent towards foundational AI components—chips, models, and interoperable systems. Avoid the temptation to only build at the application layer.
  3. The So What?: The window for shaping the future of intelligence is now. Engage in the deepest, most complex challenges to secure a footprint in this new era.
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December 18, 2025

The EU and the not-so-simple macroeconomics of AI – Luis Garicano

Epoch AI

AI
Key Takeaways:
  1. Strategic Implication: The global AI race is a zero-sum game for foundational models. Europe's best strategy is a "smart second mover" approach, focusing on the implementation layer by ensuring interoperability and data portability.
  2. Builder/Investor Note: Invest in AI that achieves true autonomy and enhances expert productivity. Be wary of markets stifled by over-regulation, which can impede AI adoption and growth.
  3. The "So What?": Europe faces a critical juncture. Without embracing AI-driven growth, its demographic and debt problems will worsen, leading to higher interest rates without the corresponding economic expansion.
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December 18, 2025

SAM 3: The Eyes for AI — Nikhila & Pengchuan (Meta Superintelligence), ft. Joseph Nelson (Roboflow)

Latent Space

AI
Key Takeaways:
  1. Vision AI Democratization: SAM 3 lowers the barrier for sophisticated vision tasks, making advanced segmentation and tracking accessible for a wider range of applications.
  2. Builder/Investor Note: Focus on domain-specific adaptations and tooling that enhance human-AI interaction for ambiguous visual concepts. The "last mile" of user intent is a key differentiator.
  3. The "So What?": SAM 3 accelerates the development of multimodal AI, particularly in robotics and video analysis, by providing a robust, scalable visual foundation for the next generation of intelligent systems.
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Crypto Podcasts

June 12, 2025

Why ETH Might Be the Most Mispriced Asset in the World

Bankless

Crypto
Key Takeaways:
  1. ETH's Narrative is Shifting: From "tech stock" to "digital oil" and "store of value," clarifying its multifaceted value.
  2. Supply Squeeze Imminent: Capped issuance plus rising demand driven by network activity and institutional adoption points to a strong supply-demand imbalance.
  3. Massive Re-rating Potential: If ETH achieves a similar status to other global reserve assets, its price could see exponential growth from current levels.
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June 11, 2025

How RLUSD Will Join USDT & USDC

Empire

Crypto
Key Takeaways:
  1. **RLUSD Rising:** Ripple's ambition is clear: make RLUSD a top 3-4 stablecoin by leveraging strategic acquisitions for mass distribution, potentially issuing billions through platforms like Hidden Road.
  2. **Acquisition = Distribution:** Ripple is effectively purchasing its market share by acquiring businesses like Hidden Road and Metaco, creating an embedded network to push RLUSD adoption.
  3. **Stablecoin Selects:** The future stablecoin landscape will likely feature 5-7 major players, not just two, and Ripple is aggressively positioning RLUSD to be one of them.
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June 11, 2025

Crypto's Next Era: TradFi IPOs or Hyperliquid, PumpFun & Solana?

Bankless

Crypto
Key Takeaways:
  1. TradFi Wants In: The success of Circle's IPO demonstrates a massive, untapped demand from traditional markets for regulated crypto exposure, potentially paving the way for a wave of crypto IPOs.
  2. ETH's Dilemma: While Ethereum is the undisputed settlement layer for stablecoins and RWAs, the direct translation of this utility to ETH asset appreciation remains a critical question, hinging on increased on-chain economic velocity.
  3. Apps are Eating: Solana's ecosystem, with stars like Hyperliquid and Pump.fun, shows that "fat applications" can generate enormous revenue and user engagement, potentially capturing more value than the underlying L1s.
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June 11, 2025

What Is Flipcash? | Ted Livingston

Lightspeed

Crypto
Key Takeaways:
  1. Digital Cash, Real Utility: Flipcash aims to make digital money feel like physical cash—instant, easy, and universally acceptable, starting with a seamless USDC experience.
  2. Solana Speed is Key: The app's core "wow" factor of instant transactions relies heavily on Solana's performance, underscoring the blockchain's capability for consumer-facing applications.
  3. Onboarding Solved?: Requiring a small purchase for an account, immediately offset by a USDC bonus, tackles the "empty wallet" problem, driving immediate engagement and demonstrating value.
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June 11, 2025

Former Fed Official & Stablecoin Expert On The Future Of Money | Robert Bench

Forward Guidance

Crypto
Key Takeaways:
  1. **Card Networks Disrupted**: Stablecoins are poised to dismantle the high-fee "tax" imposed by traditional card payment systems, with innovators like Stripe leading the charge.
  2. **Internet Re-Incentivized**: Ultra-efficient stablecoin networks (like Radius's vision) could replace the ad-driven "attention economy" with a new model of direct value exchange for digital services, driven by AI agents.
  3. **Currency Cold War Heats Up**: The race for digital currency dominance is on, with USD stablecoins, China's e-CNY, and potentially Bitcoin vying to be the backbone of the next-gen global economy, likely leading to fewer, more standardized global currencies.
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June 10, 2025

Wall Street Loves Circle, Crypto's Next Bullish Catalyst?

1000x Podcast

Crypto
Key Takeaways:
  1. Appetite is Insatiable: Investor demand for any crypto-related exposure is immense, capable of pumping stocks like Circle's despite questionable financials.
  2. Fundamentals Still (Should) Matter: Circle's low margins, high costs, and interest rate sensitivity paint a precarious picture, a "terrible company" according to one host, even if its stock moons.
  3. Hype Cycle Peaks & Troughs: The current frenzy across crypto-linked stocks (Circle, potential Ripple IPO, Coinbase, MSTR) signals significant hype, which historically precedes market corrections.
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