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AI Podcasts

September 9, 2025

Mark Cuban on the NBA, Cost Plus Drugs, and How to Fix Politics

a16z

AI
Key Takeaways:
  1. Find the "Death War." Cuban's biggest wins come from identifying industries where competitors are forced to spend billions to survive (like AI today or streaming media rights a decade ago). These moments create massive opportunities for suppliers and disruptors.
  2. Sell a Better Life, Not an Ideology. Whether in politics or business, success comes from solving people’s immediate, tangible problems. Abstract goals and ideological purity don't sell.
  3. The Real Moat is Domain Expertise + AI. The next generation of billion-dollar companies will be built by founders who can apply AI to specific, overlooked business processes, creating hyper-efficient, customized SaaS solutions.
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September 8, 2025

The Little Tech Agenda for AI

a16z

AI
Key Takeaways:
  1. Stop Regulating Ghosts. Policy should target concrete, illegal uses of AI under existing laws, not hypothetical future harms that require licensing regimes and kill startups before they can compete.
  2. Compliance is a Competitive Moat. Regulations designed for trillion-dollar companies are a death sentence for startups. A 50-state patchwork of rules would be the final nail in the coffin for a competitive AI ecosystem.
  3. Innovation Needs a Political War Chest. The pro-innovation camp has been outmaneuvered by well-organized "safetyism" advocates. Building political gravity through organized efforts like PACs is now essential to ensure America wins the AI race.
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September 5, 2025

Shakeel Hussein: Ridges Subnet 62, AI Agents Coding, Alpha to Equity, Future of Software | Ep. 61

Ventura Labs

AI
Key Takeaways:
  1. **The Agent is the Moat.** Ridges’ success with cheaper models demonstrates that the true differentiator in AI coding is the agent architecture, not just the underlying LLM. This focus on efficiency creates a sustainable business model where competitors burn cash.
  2. **Alpha-to-Equity Creates a Capital Bridge.** This model directly ties the token's value to profit-sharing equity, creating an arbitrage loop for crypto and traditional funds. It offers a powerful alternative to typical tokenomics by capturing the value of the underlying business.
  3. **The Future of Software is Supervisory.** The ultimate goal is not just a better coding autocomplete, but a tool that elevates developers and product managers to supervisors of AI engineering teams, fundamentally changing how software is created.
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September 4, 2025

The Stock Market Is The Economy Now

Forward Guidance

AI
Key Takeaways:
  1. The Market is the Economy. The old wall between Wall Street and Main Street has crumbled. The high degree of financialization means they are now a single, symbiotic entity.
  2. Your Portfolio is a Utility. The stock market is becoming a public utility for distributing national wealth, with ownership becoming nearly universal. This trend is set to accelerate.
  3. Capital is the New Labor. This system provides the foundation for an AI economy by creating a mechanism to pay people from capital returns, solving the problem of mass unemployment before it begins.
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September 4, 2025

The Day AI Solves My Puzzles Is The Day I Worry (Prof. Cristopher Moore)

Machine Learning Street Talk

AI
Key Takeaways:
  1. **Stop Confusing Hardness with Reality.** Theoretical computer science focuses on worst-case scenarios. Real-world success hinges on exploiting messy, latent structure that we can’t even formally define yet.
  2. **Intelligence is Tool-Making.** Humans aren't just powerful processors; we're tool-users who extend our cognitive workspace. AI will remain limited until it can recognize its own limitations and build the tools it needs to overcome them.
  3. **Demand Transparency Over Explainability.** For high-stakes decisions like criminal justice or medical diagnoses, proprietary black boxes are unacceptable. The right to confront your accuser extends to the algorithms that judge you.
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September 2, 2025

COVENANT :: The Holy Grail of Decentralized AI Training on Bittensor SN3 +SN39 Basilica +SN81 Grail

The Opentensor Foundation | Bittensor TAO

AI
Key Takeaways:
  1. Decentralized Training is Unlocked. The SparseLoCo optimizer makes training massive (70B+ parameter) models over the internet practical. This is Bittensor’s direct answer to the centralized AI training monopoly.
  2. The Future is Value-Added Compute. Raw decentralized compute is a commodity game. Covenant’s strategy with Basilica is to win by building unique, high-margin services on top, like verifiable inference and hardware efficiency amplification.
  3. The Full Stack is the Moat. By integrating pre-training (Templar), intelligent compute (Basilica), and post-training (Grail), Covenant is building a flywheel. This synergy creates an end-to-end pipeline that is more than the sum of its parts.
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September 2, 2025

Substack Cofounder on AI Slop Content & the Decline of Social Media

a16z

AI
Key Takeaways:
  1. **The Media War is Attention vs. Intention.** The future isn't about more content; it's a battle between algorithmically-generated "slop" designed to hijack your attention and curated culture that serves your long-term interests.
  2. **True Platform Power is Granting Freedom.** Substack's most defensible moat is counterintuitive: giving creators the power to leave. This forces the platform to innovate and earn its keep, fostering genuine loyalty over lock-in.
  3. **Creators Are the New Founders.** The unbundling of talent from media institutions mirrors VC's impact on tech. Independent creators are becoming "ambitious media founders," building new ventures on platforms that align value creation with value capture.
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August 29, 2025

The Post-Summer Market Rotation is Here | Weekly Roundup

Forward Guidance

AI
Key Takeaways:
  1. The Great Rotation is On. The post-summer period is signaling a major shift from over-extended large-cap tech into small caps (IWM) and hard assets. Improving market breadth and historical parallels suggest this rotation has legs.
  2. Inflation is Structural. Political pressure on the Fed, coupled with labor gaining power over capital, is cementing a new, higher inflation regime. Do not expect a return to the disinflationary 2010s.
  3. AI's Capex Boom Faces a Reality Check. The AI narrative is fueling a massive debt-driven capex cycle. If revenues don't keep pace, a bust is inevitable. Crypto, having already deleveraged, appears much earlier in its cycle.
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August 29, 2025

The Holy Grail of Decentralized AI Training :: SN3 Templar + SN39 Basilica + SN81 Grail

The Opentensor Foundation | Bittensor TAO

AI
Key Takeaways:
  1. Sovereign AI is Non-Negotiable. The ecosystem cannot depend on centralized entities for foundational models. Templar’s `Sparse Loco` optimizer is the technological key to unlocking truly permissionless, large-scale model pre-training.
  2. Services are the Moat, Not Compute. Basilica’s strategy confirms that raw decentralized compute is a tough business. The real value lies in building proprietary services—like verifiable inference and compute-multiplying tech—that nobody else can offer.
  3. Vertical Integration is the Endgame. The strategy is a closed loop: Templar builds the model, Basilica provides the efficient compute, and Grail makes it intelligent. This integrated pipeline is the path to putting a Bittensor-native, state-of-the-art model on the world stage.
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Crypto Podcasts

April 21, 2025

Does Crypto Have Product Market Fit? | Matty Taylor

Lightspeed

Crypto
Key Takeaways:
  1. PMF is the Real Boss: Forget the regulatory FUD; crypto's primary challenge now is the age-old startup struggle – building things people actually need and use.
  2. Solana's Pragmatic Pull: The ecosystem's intense focus on PMF over ideological purity is attracting founders eager to build real markets and applications.
  3. Show Me the Revenue (or Sticky Users): True PMF often translates to tangible results like revenue (Pump.fun, Jito) or deeply embedded usage (Bitcoin, potentially Aave), separating signal from noise.
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April 19, 2025

Crypto's Data & Transparency Problem | Roundup Clip

Bell Curve

Crypto
Key Takeaways:
  1. **Trust, But Verify Rigorously:** Assume data discrepancies exist; stated figures and dashboard metrics demand independent on-chain verification.
  2. **Standardize or Suffer:** The lack of "Crypto GAAP" hinders meaningful comparison and valuation; clear definitions and reporting cadence are essential.
  3. **Make On-Chain Data Truly Accessible:** Transparency requires more than just public ledgers; it needs standardized, verifiable, and easily accessible reporting directly from protocols.
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April 19, 2025

Why banks will be disrupted by stablecoins with Rob Hadick #crypto #markets #stablecoins #podcast

Bankless

Crypto
Key Takeaways:
  1. Stablecoins exploit bank inefficiency: They offer a direct route to bypass ~10% cross-border banking fees, meeting real demand.
  2. Dollar desire drives adoption: In high-inflation countries, stablecoins provide crucial access to the US dollar and dollar-priced goods.
  3. Currency consolidation favors majors: Geopolitical shifts may shrink the currency landscape, potentially strengthening the role of major currencies and their stablecoin counterparts (USD, EUR, RMB).
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April 18, 2025

Trade War & The Markets | EP 74

Good Game Podcast

Crypto
Key Takeaways:
  1. Brace for Trade War Impact: The economic fallout from tariffs and uncertainty is likely underestimated and poses significant downside risk to US equities and global growth.
  2. Demand Crypto Transparency: The lack of clear disclosure rules around token holdings and sales remains a critical vulnerability; solutions are needed, potentially driven by major exchanges or self-regulatory efforts.
  3. AI Value Shifts to Apps: Foundational models risk commoditization; long-term defensibility for AI startups hinges on building strong distribution and network effects on the application layer, potentially by remaining model-agnostic.
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April 18, 2025

Beyond the Hype: Crypto’s Next Phase | Roundup

Bell Curve

Crypto
Key Takeaways:
  1. **Market Bifurcation:** Expect continued divergence – select assets might surge on squeezed supply, but most face headwinds without new buyers. Stay nimble.
  2. **Efficiency is King:** Capital is scarcer. Projects must prove lean operations and clear value accrual compared to TradFi alternatives to win funding.
  3. **Transparency Unlocks Capital:** Don't wait for regulation. Proactive, standardized disclosure of financials, token flows, and operations will attract sophisticated investors and build desperately needed trust.
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April 18, 2025

Beyond the Hype: Crypto’s Next Chapter | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Efficiency is King: Protocols proving lean operations and clear value capture relative to TradTech will win scarce venture dollars.
  2. Disclose to Win: Transparency isn't optional; protocols providing clear, standardized data and disclosures will attract serious capital.
  3. Stablecoins Aren't Monolithic: Understand the nuances – payment vs. yield, US vs. global demand, issuer vs. infrastructure vs. enabled business – to capitalize on their growth.
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