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AI Podcasts

December 31, 2025

Infinity, Paradoxes, Gödel Incompleteness & the Mathematical Multiverse | Lex Fridman Podcast #488

Lex Fridman

AI
Key Takeaways:
  1. The move from a singular "Universe" view to a "Multiverse" perspective mirrors the transition from centralized monoliths to fragmented, interoperable ecosystems.
  2. Build systems that fail gracefully when hitting Gödelian limits.
  3. Truth is a vast ocean while proof is a small boat. Your roadmap must account for the reality that your system will eventually encounter truths it cannot verify.
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December 31, 2025

AI in 2026: 3 Predictions For What’s To Come (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. The Macro Pivot: Outcome-Based Intelligence. We are moving from AI as a Service to Results as a Service where software value is tied to revenue generation rather than seat licenses.
  2. The Tactical Edge: Verticalize the Data. Build in sectors with non-public outcome data to create a compounding moat that resists commoditization by foundation models.
  3. The winners of 2026 will be those who use AI to solve core human needs for connection and discovery while building defensible, data-rich business models.
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December 31, 2025

AutoGrad Changed Everything (Not Transformers) [Dr. Jeff Beck]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The Macro Transition: Moving from "Big Model" monoliths to "Lots of Little Models" where distributed Bayesian assets represent specific physical objects.
  2. The Tactical Edge: Prioritize "Object-Centered" architectures that track uncertainty. This allows robots to "phone a friend" when encountering novel data.
  3. The LLM era is hitting a wall of implicit representation. The next 12 months belong to those building explicit, causal world models grounded in physics rather than language.
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December 31, 2025

[State of Post-Training] From GPT-4.1 to 5.1: RLVR, Agent & Token Efficiency — Josh McGrath, OpenAI

Latent Space

AI
Key Takeaways:
  1. The move from "bigger is better" to "smarter is cheaper" as token efficiency becomes the primary metric for agentic success.
  2. Prioritize building on models that demonstrate high performance on "graph walk" evals to ensure your long-context applications actually work.
  3. Utilitarian and efficient models that prioritize task completion over cheery personality will dominate the developer market.
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December 31, 2025

[State of Evals] LMArena's $100M Vision — Anastasios Angelopoulos, LMArena

Latent Space

AI
Key Takeaways:
  1. The Macro Trend: The transition from static benchmarks to live human-in-the-loop evaluation. As models saturate fixed tests, the only remaining signal is subjective human preference at scale.
  2. The Tactical Edge: Monitor secret model drops on Arena to spot frontier capabilities before official releases. This provides a lead time advantage for builders choosing their tech stack.
  3. The Bottom Line: Arena is the new kingmaker. If you are building AI products, their expert-tier data is the most reliable map for navigating the frontier.
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December 31, 2025

[State of Context Engineering] Agentic RAG, Context Rot, MCP, Subagents — Nina Lopatina, Contextual

Latent Space

AI
Key Takeaways:
  1. The move from small models to medium models (15B to 70B) suggests that reasoning capability is outstripping the desire for low-latency edge deployment.
  2. Implement instruction-following re-rankers to prune your context window. This prevents the model from getting confused by irrelevant data.
  3. Stop building toys. The next year belongs to those who can build full agentic systems that handle billions of tokens without losing the plot.
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December 31, 2025

[NeurIPS Best Paper] 1000 Layer Networks for Self-Supervised RL — Kevin Wang et al, Princeton

Latent Space

AI
Key Takeaways:
  1. The wall between RL and self-supervised learning is crumbling, leading to a unified "representation-first" approach to AI.
  2. Swap your reward-heavy objectives for contrastive representation learning to access deeper, more stable architectures.
  3. If you aren't planning for RL models with 100x the current depth, you're building for the past.
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December 31, 2025

[State of AI Papers 2025] Fixing Research with Social Signals, OCR & Implementation — Team AlphaXiv

Latent Space

AI
Key Takeaways:
  1. Academic research is transitioning from a "publish or perish" PDF culture to an "implement or ignore" code culture.
  2. Use AlphaXiv to filter research by social signal and implementation ease rather than just keyword relevance.
  3. The PDF is an antiquated artifact. In 2025, the value of a paper is measured by the speed at which a developer can spin up its Docker container.
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December 31, 2025

[State of MechInterp] SAEs in Production, Circuit Tracing, AI4Science, "Pragmatic" Interp — Goodfire

Latent Space

AI
Key Takeaways:
  1. The Macro Trend: The transition from black box scaling to transparent steering. As models enter regulated industries, the ability to prove why a model made a decision becomes more valuable than the decision itself.
  2. The Tactical Edge: Deploy sidecar models for monitoring. Instead of using expensive LLM-as-a-judge prompts, probe specific internal features to catch hallucinations at the activation level.
  3. The Bottom Line: The next year belongs to the pragmatic researchers. If you cannot explain your model's reasoning, you will not be allowed to deploy it in high-stakes environments.
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Crypto Podcasts

July 23, 2025

CRYPTOCURRENCY TALK: TALOS, PUMP, ETHENA, HYPERLIQUID - 0xResearch and Friends

0xResearch

Crypto
Key Takeaways:
  1. Product Is King. The market consistently rewards applications that prioritize a simple, effective user experience. Hyperliquid’s mobile integration and the rise of intents-based bridging show that abstract infrastructure plays are losing ground to products that just work.
  2. Incentives Need a Narrative. Pump.fun’s gigantic treasury is a powerful tool, but without a clear strategy and strong communication from the team, it's not enough to prevent a massive loss of market share and investor confidence.
  3. De-Risking Is the New Black. Mature protocols like Ethena are actively moving to reduce complexity and risk, even at the cost of marginal yield. This signals a broader shift towards sustainability and resilience over chasing every last basis point.
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July 22, 2025

Empire Cross-Post: DC Crypto Week Takeaways With Rebecca Rettig & Alexander Grieve

Bell Curve

Crypto
Key Takeaways:
  1. Stablecoins are Mainstream Infrastructure. The Genius Act solidifies stablecoins as a key pillar of the future financial system. For founders and investors, the largest immediate opportunities are in building white-label issuance platforms and other ancillary services for traditional companies.
  2. ICOs Are Back, But With Guardrails. The Clarity Act paves the way for a resurgence in token pre-sales by creating a compliant fundraising path. Founders gain a new capital formation tool, while investors get a clearer framework, albeit with longer lockups for insiders.
  3. The Next Battle is Taxes. With stablecoin and market structure frameworks advancing, the next major regulatory hurdle is tax. Expect a significant push to clarify the tax treatment of staking rewards and other on-chain activities, which will be critical for integration into products like ETFs.
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July 22, 2025

The Truth Behind Crypto Market Makers | Matt Jobbé-Duval

Lightspeed

Crypto
Key Takeaways:
  1. The Call Option's Double Edge: The standard call-option deal is an elegant solution to crypto's volatility, but it becomes toxic when the loan is too large. An oversized option creates a "magnet effect" where the price gets pinned to the strike, killing healthy price discovery.
  2. "Active Market Making" Is a Trap: Selling the future to pump the present is a fool's game. This structure leverages a project’s future token supply for a short-term price pump that almost always ends in a perp-driven death spiral, destroying credibility.
  3. Launch Price Is Vanity, Momentum Is Sanity: The initial TGE price is an illusion driven by retail FOMO. Projects should focus on establishing a fair pre-launch price and using stabilization mechanisms to build sustained momentum, rather than chasing a fleeting, sky-high valuation on day one.
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July 22, 2025

Bits and Bips LIVE: July 21

Unchained

Crypto
Key Takeaways:
  1. Stablecoin Infrastructure is the New Gold Rush: The Genius Act fired the starting gun. The most significant opportunities lie not in issuing stablecoins, but in building the ecosystem around them—from payment rails to wallet design and tokenized money market funds.
  2. Narrative is the Ultimate Catalyst: ETH’s rally wasn’t driven by a tech breakthrough but by a potent cocktail of treasury-driven demand and a leadership refresh. In crypto, momentum creates its own demand.
  3. The Great Convergence is Accelerating: With Coinbase in the S&P 500 and a wave of crypto IPOs, traditional capital can no longer sit on the sidelines. The primary battleground is now for public market mindshare.
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July 21, 2025

Where Are We In The Cycle? | Willy Woo

1000x Podcast

Crypto
Key Takeaways:
  1. We are in a high-risk, high-reward phase where liquidity is the primary driver. The cycle's ultimate peak remains uncertain and heavily dependent on macro-economic policy.
  2. Brace for the Parabola. This is the late-stage bull market, where the most significant gains historically occur in short, violent bursts. Being out of the market means risking missing the entire cycle's payoff.
  3. Rotation Is in Motion. Capital has started flowing from Bitcoin to Ethereum. The next domino to watch for is a pop in large-cap alts, which would confirm a full-blown alt season is underway.
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July 21, 2025

DC Crypto Week Takeaways

Empire

Crypto
Key Takeaways:
  1. **Stablecoins are now institutional grade.** The Genius Act provides a clear regulatory framework, unlocking enterprise adoption and integration into traditional payment rails. Expect a wave of innovation in stablecoin infrastructure.
  2. **The future of DeFi is the next battleground.** While the Clarity Act offers key protections for developers, traditional finance incumbents are actively lobbying to limit DeFi's scope. The fight will be fierce in the Senate.
  3. **Capital formation is being supercharged.** The Clarity Act’s new token sale exemption will legitimize and streamline ICO-style fundraising, providing a powerful new tool for founders to raise capital with crypto-native efficiency.
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