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AI Podcasts

February 4, 2026

The Economic Singularity Will Make Today’s Economy Unrecognizable w/ Dr. Alexander Wissner-Gross

Milk Road AI

AI
Key Takeaways:
  1. AI-driven hyperdeflation will fundamentally alter economic structures, leading to a post-scarcity future where the primary challenge shifts from production to distribution and the integration of human and machine economies.
  2. Invest in infrastructure that bridges human and AI economies, or prepare for a future where AI agents become a significant, crypto-native economic force.
  3. The next 6-12 months will see continued acceleration of AI capabilities, pushing us closer to a future where traditional labor and intelligence are nearly free. Understanding this change is crucial for navigating the emerging economic landscape and identifying new value creation opportunities.
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February 5, 2026

Goodfire AI’s Bet: Interpretability as the Next Frontier of Model Design — Myra Deng & Mark Bissell

Latent Space

AI
Key Takeaways:
  1. The era of opaque, black-box AI is ending; the future demands intentionally designed models with human understanding and control. This shift is driven by reliability in high-stakes applications and extracting novel insights.
  2. Investigate interpretability tools (like Goodfire's platform) to gain granular control over model behavior, moving beyond basic fine-tuning for critical applications.
  3. Interpretability is not a niche; it's the missing piece for scaling AI safely into mission-critical domains. Mastering model understanding and intentional design will yield unprecedented capabilities and competitive advantage.
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February 4, 2026

Ep#61: 1x World Model

RoboPapers

AI
Key Takeaways:
  1. Robotics is moving from bespoke, data-hungry behavior cloning to generalized, human-informed learning via world models. This shift, mirroring the success of LLMs, means robots can use the vast, unstructured data of human experience to acquire new skills.
  2. Invest in platforms and data pipelines that facilitate multi-modal, multi-stage training for humanoid robots. Prioritize systems that can generate synthetic data and use world models for high-throughput, targeted policy evaluation.
  3. World models are the engine for scalable robot intelligence. They promise a future where robots learn faster, generalize wider, and self-improve through iterative simulation, making widespread humanoid deployment a near-term reality.
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February 3, 2026

Why The Laws of Startup Physics Have Changed | Ben Horowitz Interview

Invest Like The Best

AI
Key Takeaways:
  1. The Macro Shift: AI is collapsing the time horizon for technological deployment and market dominance, shifting the competitive advantage from pure innovation to a combination of innovation, capital, and rapid infrastructure deployment.
  2. The Tactical Edge: Invest in companies that are not just building AI, but are fundamentally rethinking existing industries with AI-first principles, recognizing that traditional software moats are eroding.
  3. The Bottom Line: The next 12-24 months will see AI's broad impact kick in, creating unprecedented opportunities for those who understand its new "laws of physics" and the critical role of policy in shaping its trajectory.
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February 4, 2026

Ozempic Won't Solve America's Obesity Problem

a16z

AI
Key Takeaways:
  1. The healthcare system is moving from reactive, acute care to proactive, preventative interventions, driven by the unsustainable costs of chronic disease and a growing understanding of environmental health.
  2. Build infrastructure that financially incentivizes lifestyle interventions, such as TrueMed's HSA/FSA payment rails for health-promoting products and services.
  3. The next decade will see hundreds of billions of dollars redirected towards preventative health. Companies that bridge the gap between lifestyle choices and healthcare financing will capture significant market share.
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February 3, 2026

SpaceX Engineer Explains America's Biggest Energy Mistake | Scott Nolan, CEO of General Matter

The Generalist

AI
Key Takeaways:
  1. The Macro Shift: Global energy demand, driven by AI, forces a strategic re-evaluation of nuclear power. This creates a window for nations to re-shore critical energy infrastructure, moving from reliance on adversaries to domestic, cost-competitive solutions.
  2. The Tactical Edge: Investigate companies addressing foundational supply chain gaps in critical industries like energy. Look for teams with a "first principles" engineering approach and a track record of commercializing hard tech.
  3. The Bottom Line: America's energy independence and its ability to power future technological growth, like AI, hinge on rebuilding domestic nuclear fuel enrichment. This is not just an industrial opportunity; it is a national security imperative.
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February 4, 2026

The Economic Singularity Will Make Today’s Economy Unrecognizable w/ Dr. Alexander Wissner-Gross

Milk Road AI

AI
Key Takeaways:
  1. The Macro Shift: AI-driven hyperdeflation is colliding with the technical reality of autonomous AI agents creating their own crypto-backed economies, threatening a decoupling from human fiat systems.
  2. The Tactical Edge: Investigate and build infrastructure that bridges human and AI economies, focusing on fiat-to-crypto rails that can accommodate agent-driven transactions to prevent a complete split.
  3. The Bottom Line: The next 5-10 years will see an unprecedented economic transformation. Understanding AI's deflationary power and the emerging AI agent economy is critical for navigating a world where traditional economic models may no longer apply.
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February 3, 2026

OpenClaw Makes AI Agents and CPUs Get Real

Semi Doped

AI
Key Takeaways:
  1. The time of practical AI agents is here, moving compute demand beyond pure GPU inference to a significant reliance on CPUs for coordination, data handling, and security.
  2. Evaluate your agent deployment strategy now, prioritizing sandboxed environments (VPS, dedicated local servers) and exploring cost-optimized model routing to manage API expenses.
  3. Prepare for a future where AI agents become integral to workflows, but recognize the hidden infrastructure costs and security implications, particularly the growing importance of CPU capacity and robust access controls.
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February 4, 2026

⚡️ Context graphs: AI’s trillion-dollar opportunity — Jaya Gupta, Ashu Garg, Foundation Capital

Latent Space

AI
Key Takeaways:
  1. The shift from "how" to "why" in AI agent capabilities creates a new, multi-trillion-dollar market for companies that can capture institutional decision logic.
  2. Invest in or build agentic systems that are in the "right path" of business processes, actively capturing decision traces from unstructured data.
  3. Hundreds of context graphs will be in production at scale within a year, defining a new "context graph stack." The winning companies will be those that master this flywheel, extracting value to accelerate automation and build deep, defensible moats.
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Crypto Podcasts

July 19, 2025

Market Melt-Up! Pump ICO! w/ Alex Good & Santiago Santos

Steady Lads Podcast

Crypto
Key Takeaways:
  1. **Fiscal, Not Fed:** This melt-up is fueled by government spending, not central bank easing. Expect momentum to push assets higher before a sharp, painful correction. Have your exit plan ready.
  2. **Trade the Politics:** The cleanest narrative trade isn’t just Bitcoin; it’s politically reflexive “hated” coins (like XRP) that benefit from deregulation and have built-in, retail-heavy communities.
  3. **Beware the Treasury Trap:** Publicly traded crypto treasury companies are an attention game designed to prey on retail liquidity. While you can dance while the music plays, know that the exit door is small.
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July 18, 2025

Hash Rate - Ep 121 - James Altucher TAOx

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

Crypto
Key Takeaways:
  1. Escape Velocity Reached: Like the early internet and Bitcoin, BitTensor has survived its infancy. Its ecosystem of 128+ subnets has created a network-effect moat that makes it incredibly difficult to disrupt.
  2. The "Front Door" Is the Next Billion-Dollar Opportunity: The most significant hurdle for BitTensor is its developer-focused user experience. The companies that successfully build simple, consumer-friendly interfaces on top of the subnets will unlock immense value.
  3. Powerful Tokenomics Signal a Supply Shock: TAO's upcoming halving, combined with its built-in utility and high staking rate, is creating a classic supply squeeze. With demand structurally increasing as the network grows, the economics point toward a significant price appreciation for the root token.
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July 18, 2025

The Great Ponzi-fication Of Markets | Weekly Roundup

Forward Guidance

Crypto
Key Takeaways:
  1. The Game Is Rigged, Play Accordingly. Traditional analysis is failing. The winning strategy is "grift arbitrage"—investing in assets that benefit from government spending and political connections.
  2. Bonds are Dead, Long Live Yield. With governments committed to fiscal dominance, bonds offer negative real returns. The hunt for yield is driving capital from fiat junk bonds into Bitcoin and Ethereum.
  3. Hedge for the Inevitable Shakeup. The system is fragile. Key risks like aggressive tariffs or a hawkish Bank of Japan could trigger a sharp sell-off. With volatility low, now is the time to buy cheap protection.
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July 19, 2025

Treasury Vehicles, Crypto Bills, 401Ks, and Retail Runups

0xResearch

Crypto
Key Takeaways:
  1. Treasury Vehicles are a Trap. They're the new high-risk, high-reward play, but the danger isn't debt—it's massive shareholder dilution and a rapid, reflexive unwind that will be far quicker and more brutal than Grayscale's.
  2. The Cycle Isn't Dead, It's Rhyming. The market is replaying the classic playbook: BTC runs, ETH surges, and capital spills into retail-favorite alts. Calling a top is a fool's errand, but the exuberance is palpable.
  3. Regulation is a Double-Edged Sword. New laws provide a path for tokens to become commodities but may incentivize projects to launch chains purely for regulatory arbitrage, adding another layer of complexity to the market.
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July 18, 2025

Ethereum’s Comeback, PumpFun’s ICO, and Crypto’s Regulatory Shift | Roundup

Bell Curve

Crypto
Key Takeaways:
  1. **Ethereum's revival is structural, not speculative.** Unprecedented ETF and corporate treasury inflows are creating sustained buying pressure that could push ETH to $10K and beyond, rendering past cynicism obsolete.
  2. **Regulation is the unlock for institutional crypto.** The Clarity and Genius Acts are not just rules; they are the green light for institutional capital that has been waiting on the sidelines for legal certainty.
  3. **The future of consumer crypto is weird and profitable.** Platforms like Pump.fun prove that the most powerful business models may not fit traditional molds but will win by tapping into raw, unfiltered user demand.
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July 18, 2025

ETH Breaks New Records While BTC Hits ANOTHER All Time High

Bankless

Crypto
Key Takeaways:
  1. The ETH Treasury Is The New Institutional Bid. The narrative that powered Bitcoin's run is now being replicated for ETH, but with a twist: former Bitcoin miners are leading the charge, creating a powerful, reflexive buy-cycle.
  2. ETH's Supply Squeeze Is Real. The combination of record ETF demand, minimal proof-of-stake issuance, and a re-staking culture means the buy pressure is overwhelming the available sell-side liquidity.
  3. Regulation Is Becoming A Tailwind. The expected passage of the stablecoin bill provides a legitimate foundation for institutional adoption, turning a long-time headwind into a powerful catalyst for growth.
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