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AI Podcasts

December 20, 2025

Are AI Benchmarks Telling The Full Story? [SPONSORED]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Strategic Shift: The market will increasingly demand AI models evaluated on human-centric metrics, not just technical benchmarks. Companies prioritizing user experience and safety will gain a competitive edge.
  2. Builder/Investor Note: Investigate companies developing or utilizing advanced, demographically representative human evaluation frameworks. These are crucial for building defensible, user-aligned AI products.
  3. The "So What?": Over the next 6-12 months, expect a growing focus on AI safety, ethical alignment, and nuanced human preference data. The "Wild West" of AI evaluation is ending, paving the way for more robust, trustworthy systems.
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December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Strategic Implication: The next frontier in AI is agentic, and progress hinges on fundamental pre-training innovation, not just post-training optimizations.
  2. Builder/Investor Note: Focus on teams with deep experience in scaling and debugging large models, as this is a high-capital, high-risk endeavor. Builders should prioritize developing new benchmarks for agentic capabilities.
  3. The "So What?": The industry needs to move beyond next-token prediction and static benchmarks to unlock truly capable, self-correcting AI agents in the next 6-12 months.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Shift in AI Development: The focus moves from syntax-aware code generation to execution-aware reasoning, enabling more robust and intelligent code agents.
  2. Builder/Investor Note: Prioritize tools and platforms that support explicit execution modeling and highly asynchronous, high-throughput RL training for agentic systems.
  3. The "So What?": AI that can simulate complex systems internally will drastically reduce development and testing costs, accelerating innovation in software and distributed systems over the next 6-12 months.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Strategic Shift: AI-driven kernel generation is not replacing human genius but augmenting it, allowing experts to focus on novel breakthroughs while AI automates the application of known optimizations across a complex hardware landscape.
  2. Builder/Investor Note: Focus on robust validation and hardware-in-the-loop systems. Claims of "AI inventing new algorithms" in this domain are premature. The real value is in automating the "bag of tricks" for heterogeneous compute.
  3. The "So What?": This technology is critical for scaling agentic AI workloads. Expect significant investment in tools that abstract hardware complexity and enable efficient, automated optimization, driving down the cost of AI inference in the next 6-12 months.
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December 18, 2025

AI Consulting in Practice – NLW, Super ai

AI Engineer

AI
Key Takeaways:
  1. The Agent Economy is Here: Enterprises are moving past pilots with AI agents. Builders should focus on orchestration layers and human-agent interaction design.
  2. ROI Measurement is the Next Frontier: Investors should look for solutions that help organizations accurately track and attribute AI value beyond traditional metrics.
  3. Strategic AI, Not Spot Solutions: The biggest wins come from systematic, cross-organizational AI strategies that target new capabilities and revenue growth, not just incremental time savings.
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December 18, 2025

How to build an AI native company (even if your company is 50 years old) – Dan Shipper, Every

AI Engineer

AI
Key Takeaways:
  1. The 100% AI adoption threshold is a step-function change, not incremental. Companies that commit fully will outpace those with partial integration.
  2. Builders should prioritize "compounding engineering" by codifying knowledge into reusable prompts. This builds an organizational memory that accelerates future development exponentially.
  3. Re-evaluate team structures and roles. Single engineers can own complex products, and even technical managers can contribute code, shifting how organizations operate.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. Effective crime reduction requires a shift from reactive punishment to proactive, intelligence-driven deterrence, making it highly probable for criminals to be caught.
  2. The market for AI-powered public safety technology, particularly solutions that integrate data for precision and accountability, presents a significant opportunity. Public-private partnerships are a key funding mechanism.
  3. Over the next 6-12 months, expect to see more cities adopt advanced surveillance and AI tools, driven by private funding, as they seek to improve safety and address staffing shortages without resorting to ineffective, broad-stroke policies.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade will be defined by who builds the core infrastructure for intelligence. This is where the most significant value and influence will accrue.
  2. Builder/Investor Note: Direct capital and talent towards foundational AI components—chips, models, and interoperable systems. Avoid the temptation to only build at the application layer.
  3. The So What?: The window for shaping the future of intelligence is now. Engage in the deepest, most complex challenges to secure a footprint in this new era.
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December 18, 2025

The EU and the not-so-simple macroeconomics of AI – Luis Garicano

Epoch AI

AI
Key Takeaways:
  1. Strategic Implication: The global AI race is a zero-sum game for foundational models. Europe's best strategy is a "smart second mover" approach, focusing on the implementation layer by ensuring interoperability and data portability.
  2. Builder/Investor Note: Invest in AI that achieves true autonomy and enhances expert productivity. Be wary of markets stifled by over-regulation, which can impede AI adoption and growth.
  3. The "So What?": Europe faces a critical juncture. Without embracing AI-driven growth, its demographic and debt problems will worsen, leading to higher interest rates without the corresponding economic expansion.
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Crypto Podcasts

January 2, 2026

Bittensor Brief #16: Bitsec Subnet 60

Hash Rate Podcast

Crypto
Key Takeaways:
  1. Security is moving from a periodic human service to a continuous machine-verified state.
  2. Stress-test your current security stack by running it against historical exploit benchmarks.
  3. If you are not using AI to defend your code, you are already losing to the AI trying to break it.
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January 2, 2026

Silver Is Going Parabolic, Bitcoin's Quantum Threat, & ETH’s 2026 Setup

Bankless

Crypto
Key Takeaways:
  1. The Macro Move: Capital is rotating from speculative "early" bets into "fundamental" infrastructure as crypto integrates with global finance.
  2. The Tactical Edge: Audit your portfolio for "equity-heavy" protocols and favor "unified" models like Uniswap that prioritize token-holder value.
  3. The Bottom Line: The next year belongs to the builders who can navigate the transition from "underground" experiment to "boring" global backbone.
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January 1, 2026

What's Next For Solana In 2026?

Lightspeed

Crypto
Key Takeaways:
  1. The "Fat Protocol" thesis is being replaced by "Fat Applications" as front-ends capture the spread between network costs and user willingness to pay.
  2. Build or invest in "Super Terminals" like Fuse that abstract gas fees and integrate banking features natively.
  3. In 2026, the winner isn't the fastest chain, but the app that makes the chain invisible. Front-ends are the new sovereign entities of the crypto economy.
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January 1, 2026

Aave Civil War + Flow Hack + Coinbase Everything Exchange - The Chopping Block

Unchained

Crypto
Key Takeaways:
  1. The Macro Movement: Infrastructure costs are creating a natural monopoly for dominant chains. Capital is migrating away from ghost chains that cannot support the $20 million annual integration tax.
  2. The Tactical Edge: Audit the IP structure of your protocol holdings. Prioritize projects where the foundation or DAO owns the primary domain to avoid "stealth privatization" risks.
  3. The Bottom Line: The next year belongs to platforms that own the user relationship and the underlying pipes. Expect a brutal consolidation where only the most integrated apps survive.
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December 31, 2025

The Type of Blockchain Banks Actually Want | Canton Network

The DCo Podcast

Crypto
Key Takeaways:
  1. The Macro Transition: Privacy-First Infrastructure. As the novelty of public ledgers fades, the market is moving toward selective transparency where institutions control data visibility.
  2. The Tactical Edge: Audit Canton. Builders should evaluate the Canton Network for any application involving sensitive corporate data or institutional capital flows.
  3. The Bottom Line: Institutional adoption won't happen on public chains as they exist today. The next phase of growth belongs to networks that treat privacy as a foundational requirement for compliance and scale.
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December 31, 2025

The Market Has Already Picked Its Winners for 2026 | Tony Greer

Forward Guidance

Crypto
Key Takeaways:
  1. The Macro Transition: The move from growth at any price to hard assets for a new order is being fueled by a combination of US political shifts and Japanese monetary instability.
  2. The Tactical Edge: Accumulate GDX and XME on pullbacks while avoiding the retail cheerleading traps in silver handles.
  3. The Bottom Line: The next 12 months will reward those who trade breakouts in physical production and energy rather than those clinging to the 2023 tech playbook.
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