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AI Podcasts

November 17, 2025

Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering

a16z

AI
Key Takeaways:
  1. Stop Trying to “Steer” AGI. The control paradigm is a dead end. The goal isn’t a more obedient tool; it’s a trustworthy teammate. We must shift from engineering control to cultivating care.
  2. Alignment is a Process, Not a Product. True alignment isn't a fixed set of rules. It’s a dynamic process of moral learning, akin to raising a child. AIs that only follow rules are brittle and dangerous.
  3. Build for Cooperation, Not Command. The technical path forward involves training AIs in rich, multi-agent environments where they must learn cooperation and theory of mind—the foundational skills for becoming a good member of a group.
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November 16, 2025

Rawson Haverty presents "US & China AI: Lessons from Across the Pacific" | dAGI Summit 2025

Delphi Digital

AI
Key Takeaways:
  1. US Leads in Capital-Intensive Frontier AI; China Excels at Industrial Diffusion. The US leverages deep capital markets for its massive compute buildout and AGI research, while China uses state direction to embed AI into its vast industrial base via open-source models and hardware.
  2. Market Structure Dictates AI Strategy. The US "efficient oligopoly" model prioritizes global dominance and profit reinvestment by a few players. China's "subjugated swarm" model creates intense domestic competition, driving down prices and accelerating adoption at the cost of profitability.
  3. Geopolitical Tension May Be a Necessary Stabilizer. The competition between the US's freedom-oriented, frontier-pushing approach and China's stability-focused, diffusion-driven model creates a complementary tension that could be essential for navigating the "narrow corridor" between AI-driven totalitarianism and uncontrollable chaos.
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November 13, 2025

How Will AI Change Gaming Development? (A Dev’s Take)

The DCo Podcast

AI
Key Takeaways:
  1. Development timelines are collapsing from months to days. AI allows developers to swap entire asset libraries or generate new game concepts at unprecedented speed, turning a two-month art project into a day's work.
  2. The lifespan of any single game is shrinking. Prepare for a world of disposable entertainment. As AI floods the market with content, the strategy will pivot from creating one long-lasting hit to deploying a rapid succession of engaging experiences.
  3. Games are the next evolution of the attention economy. Just as memes became a core tool for community-building around tokens, easily created games will be the next engine for capturing and directing user attention in a hyper-competitive digital world.
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November 11, 2025

AI Nerves, Crypto Realism, Privacy Coins, & Lessons From Trading

1000x Podcast

AI
Key Takeaways:
  1. Adopt a Stock Picker's Mentality. The crypto market is no longer a monolith where a rising tide lifts all boats. Focus on assets with real products, user growth, and cash flow, as the gap between winners and losers will only widen.
  2. Shorting is a Tactical Assault, Not a Siege. Don't "invest" in a short. The only viable short strategies are tactical, targeting specific events like VC unlocks or news-driven spikes. Otherwise, even "total scams" can 5x against you.
  3. Cultivate a Goldfish's Memory. The most critical trading skill is learning how to change your mind. Cut losing trades, forget the loss (but remember the lesson), and redeploy capital without emotional baggage. Stubbornness is a portfolio killer.
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November 11, 2025

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

a16z

AI
Key Takeaways:
  1. Word-of-mouth isn't a feature; it's the engine. Before spending a dime on marketing, obsess over the first 30 seconds of the user experience until people can't help but share it.
  2. Being different is better than being better. Don't build incrementally better slideware. Redefine the core primitives of your category, as Gamma did by moving beyond the 16x9 slide.
  3. Hire painfully slowly to protect your DNA. Resisting the temptation to scale headcount with user growth is a superpower. The goal isn't to hit a hiring target; it's to hire the best people.
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November 7, 2025

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

a16z

AI
Key Takeaways:
  1. AGI Is a Definitional Debate. Progress toward an AI that can replace a remote worker is happening fast. However, achieving "true" human-like learning efficiency may require an entirely new paradigm beyond scaling current LLMs.
  2. The New Creator Economy Is Code. AI is turning software development into a mainstream creative pursuit, empowering a new class of solo entrepreneurs who can build what previously required entire teams.
  3. Incumbents Learned Their Lesson. Unlike past tech shifts, today's giants are aggressively adopting AI, making it both a sustaining *and* disruptive force. The market is large enough for both incumbents and startups to create massive value.
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November 6, 2025

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

a16z

AI
Key Takeaways:
  1. Build the Tools, Not Just the House: CZI’s greatest leverage comes from creating open-source tools and datasets. By building the fundamental infrastructure, they empower the entire scientific community—from academic labs to startups—to accelerate discovery.
  2. Data Is the New Microscope: The future of biology hinges on a tight feedback loop between generating novel, purpose-built datasets and training domain-specific AI models on them. This synergy is unlocking insights that were previously impossible.
  3. Virtual Biology Is the Next Frontier: Simulating biology computationally with "virtual cells" will become the new standard for research, enabling scientists to test riskier hypotheses faster and cheaper, dramatically compressing the timeline for major breakthroughs.
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November 5, 2025

Seeing The Future from AI Companions to Personal Software

a16z

AI
Key Takeaways:
  1. The Interface is the Bottleneck. Today's chatbots are the MS-DOS of AI. The next trillion dollars of value will be unlocked not by the models themselves, but by the new "Windows/Mac OS" interface that makes AI accessible and useful for everyone.
  2. Every Creator Will Build Software. The distinction between a content creator and a software developer is collapsing. The next platforms will empower anyone to build mini-apps, turning software into a new medium for community, expression, and monetization.
  3. Ditch the Voice-Only Dream. The Her-inspired fantasy of a screenless, voice-only AI future is a dead end. The winning AI device will be screen-first, built around an AI-native OS that makes software deeply personal and context-aware.
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November 4, 2025

Rollup TV: Aria Protocol, Money Moves Fast EP 8, Crossmint

The Rollup

AI
Key Takeaways:
  1. Culture is the Newest Yield-Bearing Asset: Arya Protocol proves that intellectual property, from music royalties to digital art, can be tokenized into stable, income-generating investments, moving beyond crypto’s speculative roots.
  2. Fintech's Crypto FOMO is Reshaping Finance: The race is on. Traditional payment giants are rapidly adopting stablecoins, not as a gimmick, but as a critical infrastructure upgrade for building faster, cheaper, and more inclusive global financial products.
  3. Money is Becoming Natively Programmable for AI: The future of commerce and finance will be run by AI agents. Stablecoins provide the missing piece—a programmable, automated payment layer that bypasses the friction of traditional banking, unleashing a new wave of economic activity.
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Crypto Podcasts

February 1, 2026

Crypto is so Cooked.

Taiki Maeda

Crypto
Key Takeaways:
  1. The Macro Shift: Institutional capital flow dictates market cycles; the current downturn purges weak projects, paving the way for a value-driven recovery.
  2. The Tactical Edge: Identify projects with genuine value accrual, strong fundamentals, and potential for buybacks, preparing to dollar-cost average into these "Carvana" plays.
  3. The Bottom Line: The current "gross" feeling is a signal to strategically deploy capital into long-term, high-conviction assets, rather than short-term trading.
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February 1, 2026

Looking for Gains Right Now? Crypto Isn’t the Trade — This Is: Bits + Bips

Unchained

Crypto
Key Takeaways:
  1. Capital is migrating from speculative, long-tail crypto assets to tokenized real-world assets and sophisticated derivatives. This reflects a broader market demand for yield, hedging, and perceived stability.
  2. Explore tokenized commodities (gold, silver) and equity perpetuals for new leverage and yield opportunities. Exercise extreme caution with prediction markets and weekend tokenized equity trading due to information asymmetry and manipulation risks.
  3. The crypto market is maturing beyond pure digital assets, integrating with traditional finance through tokenization and derivatives. Position your portfolio to capture value from this convergence, prioritizing robust liquidity and verifiable information over pure speculation.
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January 31, 2026

New Fed Chair Nominee Kevin Warsh, Gold and silver plunge and the Rotation Trade is On.

The Rollup

Crypto
Key Takeaways:
  1. The Macro Reallocation: As global liquidity loosens and traditional assets falter, capital is migrating from "atoms" (metals) to "bits" (crypto), particularly into DeFi protocols offering superior yield and ownership.
  2. The Tactical Edge: Investigate DeFi neo-banks like Superform that aggregate yield, simplify UX, and offer tokenized ownership. These platforms are positioned to capture retail and institutional capital seeking higher returns and self-custody.
  3. The Bottom Line: A crypto-friendly Fed, capital rotation from traditional assets, and maturing user-owned DeFi platforms mean the next 6-12 months will see significant growth in onchain finance, making it a critical area for strategic investment and building.
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January 31, 2026

Why Altcoins Are Dead & What's Replacing Them with Bitget CEO, Gracy Chen

The Rollup

Crypto
Key Takeaways:
  1. Global liquidity, traditionally seeking refuge in gold and equities, is increasingly flowing into Bitcoin and tokenized real-world assets on compliant crypto platforms. This economic reality is forcing exchanges to prioritize regulated, high-value offerings over speculative altcoins.
  2. For builders, pivot from pure cryptonative narratives to projects with tangible products, clear revenue models, and infrastructure plays (RWA, AI, stablecoins). For investors, accumulate Bitcoin and explore tokenized traditional assets on compliant universal exchanges, recognizing the market's flight to quality.
  3. The crypto market is maturing, demanding real value and regulatory adherence. Over the next 6-12 months, success will hinge on participating in platforms and projects that bridge traditional finance with blockchain, leaving pure altcoin speculation behind.
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January 30, 2026

Blame Exchanges for Holding Up the Market Structure Bill? - DEX in the City

Unchained

Crypto
Key Takeaways:
  1. Policy Stalled: The prospects for comprehensive crypto market structure law are deteriorating, with political finger-pointing hindering progress. This means continued uncertainty for builders and investors, forcing operations into a legal gray area with unpredictable outcomes.
  2. Custody Failures: The US government's handling of seized crypto assets, like the alleged $40 million theft from a Bitfinex hack wallet by a contractor's son, reveals alarming security gaps. This highlights that even state actors struggle with basic digital asset security, raising questions about their ability to regulate the space effectively.
  3. Misplaced Focus: Trump's $5 billion lawsuit against JP Morgan for account closures is not true debanking, which impacts ordinary individuals and crypto businesses. This lawsuit distracts from the systemic issue of banks cutting off access to financial services for legitimate businesses without transparency or recourse.
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January 31, 2026

How Ethereum May Have One-Upped Bitcoin in One Big Way - Uneasy Money

Unchained

Crypto
Key Takeaways:
  1. The Macro Shift: AI's recursive self-improvement is compressing innovation cycles and dissolving engineering moats, creating an urgent demand for crypto infrastructure that can adapt to unforeseen technological advancements.
  2. The Tactical Edge: Prioritize protocols and platforms that demonstrate a proactive approach to long-term technical risks, such as quantum computing, over those with rigid, unadaptable architectures.
  3. The Bottom Line: The convergence of AI and crypto will redefine security and value. Ethereum's strategic investment in quantum resistance positions it to capture a significant narrative and technical advantage, while Bitcoin's inertia could become a critical liability over the next 6-12 months.
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