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AI Podcasts

August 22, 2025

The State of AI: Growth, Fragmentation, and the Next Wave

a16z

AI
Key Takeaways:
  1. Zero-Sum is a Losing Bet. The market isn't a monolith. Value is fragmenting across specialized applications in code, image, and vertical workflows. The "winner-take-all" thesis is dead.
  2. Moats are Made, Not Inherent. AI’s magic solves the "bootstrap problem" of user acquisition, but long-term defensibility requires building traditional software moats like brand, workflow integration, and network effects.
  3. Be on the Field, but Pick Your Spot. This is not a market to sit out, but indiscriminate investing is a death sentence. Back exceptional, proven teams, understand that conflicts can lock you out of the best deals, and never confuse market heat with genuine momentum.
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August 21, 2025

Can AI Fix Housing and Healthcare Affordability?

a16z

AI
Key Takeaways:
  1. AI is the deflationary force for stagnant sectors. While software ate the world, it skipped housing and healthcare. AI is finally tackling the operational drag that has caused costs to balloon for decades.
  2. To solve the housing crisis, make it profitable. The path to more housing supply runs through better returns. By making property operations radically more efficient, AI attracts the capital required to build.
  3. The future of work is human + AI. Automation won't eliminate jobs; it will transform them. As AI handles the administrative grind, human roles will shift to higher-value work like community engagement and complex problem-solving.
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August 19, 2025

Hash Rate - Ep 129 - Macrocosmos IOTA (sn9) and DataUniverse (sn13)

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI
Key Takeaways:
  1. DTO Means Business: Dynamic TAO has forced a Darwinian shift. Subnets must now achieve product-market fit and generate real revenue to survive, transforming from research projects into self-sustaining businesses.
  2. IOTA’s Grand Ambition: IOTA (SN9) isn't just another model trainer; its architecture aims to train trillion-parameter models on decentralized, consumer-grade hardware, directly challenging the dominance of centralized AI labs.
  3. Time to Garden: The protocol's long-term health hinges on active governance. A strong sentiment is emerging to prune low-effort or malicious subnets to focus emissions on projects capable of creating real, lasting value.
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August 19, 2025

Hash Rate - Ep 128 - Ridges ($TAO Subnet 62)

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI
Key Takeaways:
  1. AI Is Moving from Copilot to Pilot. Ridges is betting that the future isn't AI assisting humans, but AI replacing them for specific tasks. Their goal is to make hiring a software engineer as simple as subscribing to a service.
  2. Decentralized Economics Are a Moat. By leveraging Bittensor's incentive layer, Ridges outsources a $15M/year R&D budget to a global pool of competing developers, achieving a cost structure and innovation velocity that centralized players cannot match.
  3. The Breakout Subnet Is Coming. Ridges showcases how a Bittensor subnet can solve real-world business problems—privacy, cost, and quality degradation—to build a product that is not just cheaper, but fundamentally better than its centralized counterparts.
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August 18, 2025

Dylan Patel on GPT-5’s Router Moment, GPUs vs TPUs, Monetization

a16z

AI
Key Takeaways:
  1. From Performance to Profit: The AI industry is pivoting from a war of benchmarks to a game of unit economics. Features like GPT-5’s router signal that cost management and monetization are now as important as model capabilities.
  2. Hardware is a Supply Chain Game: Nvidia’s true moat is its end-to-end control of the supply chain. Competitors aren't just fighting a chip architecture; they're fighting a logistical behemoth that consistently out-executes on everything from memory procurement to time-to-market.
  3. The Grid is the Limit: The biggest check on AI’s expansion is the physical world. The speed at which new power infrastructure and data centers can be built will dictate the pace of AI deployment in the US, creating a major advantage for those who can build faster.
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August 18, 2025

Subnet 56 :: Gradients :: Bittensor End-to-end AI Model Training Suite

Opentensor Foundation

AI
Key Takeaways:
  1. Performance is Proven, Not Promised. Gradients isn't just making claims; it’s delivering benchmark-crushing results, consistently outperforming centralized incumbents and producing state-of-the-art models.
  2. Open Source Unlocks the Enterprise. The shift to verifiable, open-source training scripts is a direct solution to customer data privacy concerns, turning a critical vulnerability into a competitive advantage.
  3. The AutoML Flywheel is Spinning. The network's competitive, tournament-style mechanism creates a self-optimizing system that continuously aggregates the best training techniques, ensuring it remains at the cutting edge.
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August 16, 2025

Google DeepMind Lead Researchers on Genie 3 & the Future of World-Building

a16z

AI
Key Takeaways:
  1. **World Models Are a New Modality.** Genie 3 is not just better video; it's an interactive environment generator. This divergence from passive, cinematic models like Veo signals a new frontier focused on agency and simulation, creating a distinct discipline within generative AI.
  2. **Simulation Is the Key to Embodied AI.** The biggest hurdle for robotics is the lack of realistic training environments. Genie 3 tackles this "sim-to-real" gap head-on, providing a scalable way to train agents on infinite experiences before they ever touch physical hardware.
  3. **Emergent Properties Will Drive the Future.** Key features like spatial memory and nuanced physics weren't explicitly coded but emerged from scaling. The next breakthroughs in world models will come from discovering these unexpected capabilities, not just refining existing ones.
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August 15, 2025

Greg Brockman on OpenAI's Road to AGI

Latent Space

AI
Key Takeaways:
  1. AGI is a Compute Game. The primary bottleneck is compute. The process is one of "crystallizing" energy into compute, then into the potential energy of a trained model. More compute means more intelligence.
  2. The Future is a "Manager of Models." AGI won't be a single entity. It will be an orchestrator that delegates tasks to a fleet of specialized models, from fast local agents to powerful cloud reasoners.
  3. Build for Your AI Coworker. To maximize leverage, structure codebases for AI. This means self-contained modules, robust unit tests, and clear documentation—treating the AI as a team member, not just a tool.
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August 15, 2025

Novelty Search August 14, 2025

taostats

AI
Key Takeaways:
  1. Performance is a Solved Problem. For post-training tasks, Gradients has established itself as the best in the world. Developers should stop writing custom training loops and leverage the platform to achieve superior results faster and cheaper.
  2. Open Source Unlocks Trust and Revenue. The pivot to open source directly addresses the biggest enterprise adoption hurdle—data privacy. This move positions Gradients to capture significant market share and drive real revenue to the subnet.
  3. The Bittensor Flywheel is Real. Gradients didn't just beat a major AI lab; its incentive mechanism ensures it will continue to improve at a pace traditional companies cannot match. Miners who don’t innovate are automatically replaced, creating a relentless drive toward optimization.
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Crypto Podcasts

February 6, 2026

Why Is Crypto Crashing? | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Global liquidity expands, but new investment narratives (AI, commodities, tokens) grow faster. This "dilution of attention" pulls capital from speculative crypto, favoring utility or established brands.
  2. Focus on Bitcoin and revenue-generating crypto, or explore spread trades (long Bitcoin, short altcoins). Institutional interest builds in regulated products and yield strategies for Bitcoin.
  3. The market re-rates crypto assets on tangible value, not speculative hype. Expect pressure on altcoins without clear revenue, while Bitcoin and utility-driven projects attract smart money.
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February 6, 2026

Forecasting Crypto Market Regimes

0xResearch

Crypto
Key Takeaways:
  1. DeFi is building sophisticated interest rate derivatives that provide predictive signals for broader crypto asset prices. This signals a maturation of onchain financial markets, moving closer to TradFi's analytical depth.
  2. Monitor the USDe term spread on Pendle, especially at its extremes (steep backwardation or contango), to anticipate shifts in Bitcoin's 90-day return skew and underlying yield regimes.
  3. Understanding Pendle's USDe term structure provides a powerful, data-driven lens to forecast crypto market sentiment and interest rate movements, offering a strategic advantage for investors navigating the next 6-12 months as onchain finance grows more complex.
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February 6, 2026

Bittensor Novelty Search :: SN64 Chutes :: Serverless AI compute 🪂

The Opentensor Foundation | Bittensor TAO

Crypto
Key Takeaways:
  1. The Macro Shift: AI compute is commodifying, shifting from centralized, overcapitalized data centers to globally distributed, incentive-aligned networks. This decentralization drives down costs, increases resilience, and enables unprecedented privacy.
  2. The Tactical Edge: Builders should explore Chutes' TE-enabled agent hosting and "Sign in with Chutes" OAuth system for private, cost-effective AI applications. Investors should recognize the long-term value of protocols aligning incentives for distributed compute.
  3. The Bottom Line: Chutes is building the foundational, trustless intelligence layer for the decentralized web. Its focus on privacy, efficiency, and community-driven agent development positions it as a critical piece of the Bittensor ecosystem and a potential disruptor to traditional AI giants.
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February 6, 2026

Why Everything Broke at Once (Crypto, Tech, Gold) & What Happens Next...

Bankless

Crypto
Key Takeaways:
  1. The Macro Shift: Global markets are resetting crowded growth trades, with AI's disruptive force and shifting monetary policy impacting everything from tech stocks to crypto. This period is exposing underlying correlations and forcing a re-evaluation of long-held strategies.
  2. The Tactical Edge: Maintain psychological discipline and consider dollar-cost averaging into assets with strong fundamentals. Pay close attention to Ethereum's evolving technical roadmap, as specialized L2s and L1 scaling become central.
  3. The Bottom Line: This market downturn, while painful, is a crucible for conviction. For resilient investors and builders, it presents a rare opportunity to accumulate assets and build infrastructure that will define the next cycle.
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February 6, 2026

Vitalik Keeps Selling, Zhu Su maps the next cycle, Relay Raises $17M, Figure crosses $22B in HELOCs

The Rollup

Crypto
Key Takeaways:
  1. The "crypto casino" is giving way to "neo finance," where AI and traditional finance converge on blockchain rails. This means a fundamental re-evaluation of what constitutes "value" in crypto, moving from speculative tokens to real-world asset tokenization and critical infrastructure.
  2. Focus on infrastructure plays and real-world asset (RWA) tokenization platforms. Investigate projects that streamline institutional workflows or enable high-yield stablecoin products for retail, as these areas show sustainable growth independent of speculative market cycles.
  3. The next 6-12 months will see a continued bifurcation: the old speculative crypto market will consolidate, while the "neo finance" sector, powered by stablecoins, tokenized assets, and seamless cross-chain tech, will solidify its foundations. Position yourself to build or invest in solutions that bridge traditional finance with blockchain utility, rather than chasing ephemeral token pumps.
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February 6, 2026

The AI Privacy Problem No One's Talking About in AI with George Zeng

The Rollup

Crypto
Key Takeaways:
  1. The rise of powerful AI agents (like OpenClaw) creates an urgent need for secure, private compute. This isn't just about data protection; it's about enabling a truly decentralized, user-owned AI future, mirroring the internet's evolution from walled gardens to an open web. Centralized LLMs, even without ads, still collect and use sensitive user data, making confidential compute (TEEs) and local-first models essential for trust and control.
  2. Implement AI agents within confidential virtual machines (TEEs) and establish separate, quarantined accounts for them. This protects your core digital identity and assets from potential leaks or prompt injection attacks, allowing you to experiment with agent capabilities without exposing critical data. Consider open-source models for 90% cost savings and improved privacy.
  3. The next 6-12 months will see AI agents move from novelty to necessity. Builders and investors must prioritize privacy-preserving infrastructure and user-owned AI paradigms to capture this value securely. Ignoring these foundational security layers risks catastrophic data breaches and undermines the trust required for widespread agent adoption, making decentralized, confidential solutions a competitive differentiator.
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