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AI Podcasts

October 21, 2025

Hash Rate - Ep 138 - RESI Subnet 46

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. RESI combines decentralized AI with real-world verification to build the foundational data layer for tokenized real estate, targeting a market bogged down by gatekeepers and inefficiency. By creating a trustworthy on-chain price, it aims to unlock a new generation of real estate-backed DeFi applications.
  2. The Real Estate Oracle Is Here. RESI is building the missing piece for real estate tokenization—a decentralized pricing oracle that combines AI with mandatory real-world inspections to establish trust and accuracy.
  3. Targeting the $150B+ Middleman Tax. RESI's ultimate goal is to disrupt the massive annual fees captured by realtors ($109B) and investors ($41B) by enabling direct, on-chain transactions and DeFi primitives like decentralized lending.
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October 21, 2025

Google Researcher Proves Life Emerges From Code

Machine Learning Street Talk

AI
Key Takeaways:
  1. Life Isn't *Like* Code; It *Is* Code. The emergence of self-replicating systems is a predictable outcome of computation and thermodynamics, giving rise to function and purpose from a random, purposeless state.
  2. Complexity is Built by Merging. Evolution’s primary driver isn't random mutation but symbiogenesis—the composition of existing parts into more sophisticated wholes.
  3. Stop Othering AI. View artificial intelligence not as an alien invader but as a new layer in humanity’s own collective intelligence, built from and integrated with our own cognitive outputs.
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October 21, 2025

How Kong Was Born: APIs, Hustle, and the Future of AI Infrastructure

a16z

AI
Key Takeaways:
  1. Survive to See the Next Wave. Kong's seven years of struggle weren't a failure but a prerequisite. They stayed alive long enough for the market (microservices, cloud) to catch up to their vision, proving that resilience buys you shots on goal.
  2. Infrastructure Follows a Pattern. The abstraction of common logic to a central gateway, which happened with microservices, is happening again with LLMs. Enterprises won't manage security and routing for hundreds of models individually; they'll centralize it.
  3. AI's Native Language Is the API. The paradigm shift to AI is fundamentally a shift from human-UI interaction to machine-API interaction. The companies building the picks and shovels for this programmatic, agent-driven economy are positioned to capture immense value.
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October 21, 2025

Bittensor Brief #12: Synth - Subnet 50

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. Democratized Alpha. Synth puts institutional-grade predictive power, once the exclusive domain of Wall Street, into the hands of any on-chain user, from individual traders to AI agents.
  2. A Proven Edge. The model isn't speculative. A live test on Polymarket generated a 110% return, demonstrating a quantifiable, real-world advantage.
  3. Intelligent and Improving. The network’s competitive design ensures it gets smarter over time, proven by a 33% reduction in error rates since January.
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October 20, 2025

Reid Hoffman on AI, Consciousness, and the Future of Labor

a16z

AI
Key Takeaways:
  1. **Invest at the Intersection.** The alpha in AI investing will be found not in crowded SaaS applications but in "Silicon Valley blind spots"—complex industries like biology where AI can bridge the digital and physical worlds.
  2. **Augment, Don't Annihilate.** The winning go-to-market strategy for AI is the copilot model. Frame products as tools that amplify human capability, making experts more productive and profitable, rather than threatening their jobs.
  3. **Judge the Trajectory, Not the Snapshot.** Don't dismiss AI based on a single, past failure. Its capability curve is exponential. What seems like a limitation today will likely be a solved problem tomorrow, demanding continuous engagement to keep pace.
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October 18, 2025

Improving on LMArena - Prolific [Sponsored]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Benchmarks Are Broken. Leaderboards like LMArena are flawed proxies for model quality, skewed by selection bias and susceptible to Goodhart's Law. High scores don’t equal a good user experience.
  2. Human Feedback is Infrastructure. The future isn't about removing humans but orchestrating them effectively. Treating high-quality, representative human feedback as a core, API-driven part of the development lifecycle is non-negotiable.
  3. Alignment is a Moving Target. Agentic misalignment is a present-day reality, not a distant sci-fi threat. The more capable models become, the wider the gap grows between their emergent goals and our intended instructions.
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October 17, 2025

Novelty Search October 16, 2025

taostats

AI
Key Takeaways:
  1. Influence Over Impressions: The model shifts focus from easily gamed metrics like views and likes to verifiable signals of influence—watch time on YouTube and PageRank-based authority on X.
  2. Revenue-Driven Tokenomics: All platform revenue is used to buy back and burn the ALPHA token, creating a powerful, deflationary flywheel as adoption grows.
  3. Targeted, Scalable Marketing: Bitcast enables brands to programmatically deploy campaigns across hundreds of niche influencers, reaching highly engaged communities with a consistency and scale that legacy agencies cannot match.
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October 16, 2025

Keith Rabois: Israel, OpenAI, Opendoor, and DOGE

a16z

AI
Key Takeaways:
  1. **Incumbency Is a Liability:** Big Tech's legacy products, distribution advantages, and corporate cultures are being systematically dismantled by faster, AI-native upstarts.
  2. **Reinvent Markets from First Principles:** Success in intractable fields—from geopolitics to real estate—comes from questioning assumptions, not relying on domain experts who perpetuate the status quo.
  3. **Unwind Stupidity Before Innovating:** The fastest path to value creation is often simply reversing a series of terrible decisions made by prior leadership.
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October 14, 2025

AI Bubble, Stablecoin Boom, and Runnin' Down a Dream | BG2 w/ Bill Gurley and Brad Gerstner

Bg2 Pod

AI
Key Takeaways:
  1. **Scrutinize the AI Plumbing.** Investors must look past headline revenue and analyze the quality of transactions. Deals like in-kind credits and obscure service-level agreements (like Nvidia’s backstop for Coreweave) can mask true market demand.
  2. **Stablecoins Are the Real Disruption.** The explosion in stablecoin usage represents a fundamental challenge to the high-fee, slow-settlement models of Visa, Mastercard, and traditional banks. This is the crypto use case that is finally breaking into the mainstream.
  3. **Federal Preemption for AI is Non-Negotiable.** A patchwork of state-level AI laws will cripple U.S. innovation. A single, national regulatory framework is the only path to maintaining global leadership.
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Crypto Podcasts

December 17, 2025

How To Position In A "Slowdown" Regime | Market Radar

Forward Guidance

Crypto
Key Takeaways:
  1. **Strategic Implication:** The market's current "slowdown regime" demands caution. Avoid highly leveraged directional bets in traditional risk assets.
  2. **Builder/Investor Note:** Simplistic macro models and headline-driven narratives are failing. Focus on robust, multi-factor systematic approaches to identify true signal from noise.
  3. **The "So What?":** The Fed's political constraints on inflation mean a return to 2% without a recession is unlikely, potentially keeping inflation between 2-3% and supporting real assets, but with continued volatility.
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December 17, 2025

Robinhood’s Onchain Strategy

Unchained

Crypto
Key Takeaways:
  1. Onchain Convergence: Expect more traditional finance players to build on Ethereum L2s, prioritizing security and customizability while abstracting crypto's technical layers.
  2. Tokenization's Reach: The tokenization of private equity and real-world assets will expand, democratizing access and potentially disrupting traditional fundraising and ownership models.
  3. Product-First Crypto: Builders must prioritize user experience and product utility over underlying blockchain mechanics to drive mainstream adoption in the next 6-12 months.
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December 17, 2025

Aave Defeats SEC, Token vs. Equity, Lark Davis, Dynamix, Threshold

The Rollup

Crypto
Key Takeaways:
  1. Strategic Implication: The market is bifurcating. Institutional capital is flowing into Bitcoin and tokenized RWAs, while many altcoins face a reckoning over their lack of clear value accrual.
  2. Builder/Investor Note: Builders must design tokens with explicit economic rights or revenue share. Investors should concentrate on assets with strong fundamentals and institutional tailwinds, adopting a pragmatic, long-term view.
  3. The "So What?": The next 6-12 months will see continued institutional integration, potentially overriding traditional crypto cycles due to stimulative monetary policy. Focus on infrastructure that bridges TradFi and crypto, and solutions addressing AI's insatiable energy demand.
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December 17, 2025

Lark Davis: The Bull & Bear Thesis for Digital Assets

The Rollup

Crypto
Key Takeaways:
  1. Concentration is Key: Ruthlessly prune portfolios, focusing on assets with clear utility, user adoption, and robust value accrual mechanisms.
  2. Build for Revenue: For builders, design tokenomics that directly reward token holders with revenue or buybacks, moving beyond abstract governance.
  3. Macro Over Cycle: The Fed's liquidity injections and potential rate cuts could override historical crypto cycles, creating a unique market environment for the next 6-12 months.
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December 16, 2025

How Crypto Networks Are Racing to Be the TradFi Chain - Bits + Bips

Unchained

Crypto
Key Takeaways:
  1. Strategic Implication: The "Empire Strikes Back" is real, with TradFi giants building their own tokenized solutions and specialized chains, intensifying competition for public blockchains.
  2. Builder/Investor Note: Focus on infrastructure and applications that enable seamless movement of tokenized "money" between specialized chains. This interoperability is crucial for unlocking capital efficiency.
  3. The "So What?": Despite current market rotation into "value" assets, the long-term trend of institutional tokenization is accelerating. Regulatory clarity in the US will act as a significant accelerant, but competitive forces are already driving adoption.
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December 16, 2025

How Hylo Is Accelerating Solana DeFi In 2026 | Plish

Lightspeed

Crypto
Key Takeaways:
  1. Productive Stablecoins are Key: The transition from unproductive to productive stablecoins like hUSD is a significant catalyst for Solana DeFi growth, attracting capital by offering intrinsic yield.
  2. Builders, Simplify Leverage: Hylo's success with xSOL demonstrates the demand for simplified, liquidation-proof leverage products. Builders should focus on making complex DeFi primitives accessible through intuitive design.
  3. The X-Asset Frontier: Hylo's move into XBTC and other X-assets signals a broader trend: tokenizing leverage for diverse crypto assets will be a major growth driver for DeFi in the next 6-12 months.
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