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AI Podcasts

December 13, 2025

Minimax M2 – Olive Song, MiniMax

AI Engineer

AI
Key Takeaways:
  1. **The "Small is Mighty" Paradigm:** Don't underestimate smaller, specialized models. M2 proves that smart engineering, real-world feedback, and iterative reasoning can outperform larger models in specific, high-value domains.
  2. **Builders, Embrace Iteration:** Design your agents with "interleaved thinking." The ability to self-correct and adapt to noisy environments is critical for real-world utility.
  3. **The "So What?":** The next wave of AI agents will be defined by their robustness, cost-effectiveness, and ability to generalize across dynamic environments. M2 is a blueprint for building practical, scalable AI that developers will actually integrate into their daily workflows.
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December 11, 2025

No Priors Ep. 143 | With ElevenLabs Co-Founder Mati Staniszewski

No Priors: AI, Machine Learning, Tech, & Startups

AI
Key Takeaways:
  1. Strategic Shift: The future of human-computer interaction is voice-first, moving from static content to dynamic, personalized, and agentic experiences.
  2. Builder/Investor Note: Defensibility in AI is increasingly found in deep product layers, specialized architectural breakthroughs (especially in audio), and robust ecosystems, not just raw model scale.
  3. The "So What?": Over the next 6-12 months, expect to see significant advancements in proactive AI agents, immersive media, and personalized education, with voice as the core interface.
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December 10, 2025

The Unicorn Founder Who Delegated Everything.

a16z

AI
Key Takeaways:
  1. The AI-Delegation Revolution is Here: Start experimenting with AI tools like ChatGPT for delegation now. The future involves proactive machine assistants deeply integrated into your workflow.
  2. Builders & Investors: Focus on "How to Delegate": The biggest constraint isn't finding assistants, but teaching clients how to delegate effectively. Tools and services that educate delegators will win.
  3. Reclaim Your Ambition: By offloading the mundane, you free up mental bandwidth to think bigger, pursue more ambitious goals, and ultimately, control your most valuable asset: time.
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December 12, 2025

AI Eats the World: Benedict Evans on the Next Platform Shift

a16z

AI
Key Takeaways:
  1. Strategic Implication: The AI bubble is inevitable. Focus on defensible positions: deep product integration, proprietary data, and distribution, rather than just raw model performance.
  2. Builder/Investor Note: The opportunity lies in productizing AI for specific "jobs to be done" within niche industries, creating intuitive UIs, and building in validation, not just building another foundational model.
  3. The "So What?": We're about to figure out the true "job to be done" for many industries. AI will unbundle existing businesses by exposing their hidden inefficiencies or non-obvious defensibilities.
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December 13, 2025

The Mathematical Foundations of Intelligence [Professor Yi Ma]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Embrace Parsimony and Self-Consistency: Adopt these principles as guiding forces in AI design. Build models that not only compress data efficiently but also maintain a high degree of self-consistency to ensure accurate and reliable world models.
  2. Focus on Abstraction, Not Just Memorization: Prioritize developing systems that can abstract knowledge beyond mere memorization. Move beyond surface-level compression and aim for models that can discover and reason about the underlying principles of the world.
  3. Understand and Reproduce the Brain’s Mechanisms: Focus on understanding and reproducing the mechanisms in the human brain that enable deductive reasoning, logical thinking, and the creation of new scientific theories to truly push AI to the next level.
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December 10, 2025

Nav Kumar: Trishool, AI Alignment, Subnet 23, Mechanistic Interpretability, Rogue LLMs | Ep. 75

Ventura Labs

AI
Key Takeaways:
  1. **Prioritize AI Safety Research:** Invest aggressively in understanding and mitigating AI risks to safeguard humanity against potential rogue LLMs.
  2. **Support Decentralized AI Alignment:** Champion decentralized platforms like Bit Tensor and initiatives like Trishool that promote open and transparent AI alignment research.
  3. **Embrace Mechanistic Interpretability:** Drive the development of tools that enable us to understand and control the internal workings of AI models, ensuring alignment with human values.
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December 10, 2025

Everyone Needs an Assistant. Here’s Why.

a16z

AI
Key Takeaways:
  1. Embrace Delegation as a Foundational Skill: Whether you leverage AI or human support, mastering delegation is paramount for unlocking personal and professional potential.
  2. Prioritize Time Ownership: Recognize time as your most valuable asset and design your life and calendar around your highest goals.
  3. Start Small, Scale Intentionally: Begin with affordable AI tools and gradually incorporate human assistance as your budget and needs evolve, building trust and compounding leverage over time.
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December 8, 2025

Building The Chip That Could Unlock AGI | Naveen Rao

a16z

AI
Key Takeaways:
  1. **Embrace Analog:** Explore and invest in analog computing solutions to overcome the energy limitations of current digital AI systems.
  2. **Prioritize Causality:** Shift focus towards AI models that incorporate time and causality, potentially unlocking more advanced and human-like intelligence.
  3. **Support Hardware Innovation:** Invest in and foster startups like Unconventional AI that are tackling fundamental challenges in AI hardware.
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December 8, 2025

Why AI Will Have To Run On Blockchains

The DCo Podcast

AI
Key Takeaways:
  1. Blockchain is essential for AI to ensure censorship resistance and uninterrupted accessibility.
  2. Trustworthy AI agents require on-chain governance to manage assets securely and transparently.
  3. AI agents can drastically accelerate blockchain adoption and optimize corporate processes.
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Crypto Podcasts

February 27, 2025

Why MegaETH Leaves Consensus to Ethereum

The DCo Podcast

Crypto

Key Takeaways:

  • :
  • 1. Enhanced Security through Ethereum: By outsourcing consensus to Ethereum, MegaETH leverages a highly secure and decentralized network, minimizing vulnerabilities associated with centralized consensus mechanisms.
  • 2. Performance Optimization: Avoiding its own consensus process allows MegaETH to reduce latency and boost transaction speeds, making it a high-performance blockchain solution.
  • 3. Strategic Leveraging of Established Protocols: Developers and investors should consider the benefits of utilizing established consensus protocols like Ethereum’s to ensure robust security while focusing on other aspects of blockchain performance.
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February 25, 2025

The State Of Crypto & AI | Illia Polosukhin & Bowen Wang

Lightspeed

Crypto
AI
Infrastructure

Key Takeaways:

  • :
  • 1. NEAR is pioneering a unified blockchain infrastructure integrating AI, eliminating the need for multiple chains and enhancing user experience.
  • 2. The launch of NEAR 2.0 with fully sharded architecture and reduced block times positions NEAR as a scalable and high-performance blockchain platform.
  • 3. NEAR’s focus on chain abstraction and Trusted Execution Environments sets it apart from other blockchain and Layer 2 solutions, offering a more seamless and secure user experience.
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February 25, 2025

Futarchy Deep Dive: Can Markets Make Better Decisions? | Proph3t

Bell Curve

Crypto
AI
Others

Key Takeaways:

  • :
  • 1. Futarchy harnesses market efficiency to potentially outperform traditional governance in decision-making.
  • 2. Crypto’s regulatory resistance is essential for implementing innovative governance models like futarchy.
  • 3. Enhanced liquidity and decentralized capital formation are critical for the scalability and success of futarchy-based organizations.
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February 24, 2025

Where Does Crypto Go From Here? | EP 71

Good Game Podcast

Crypto
AI
Infrastructure

Key Takeaways:

  • 1. Focus on Financial Utility: Crypto's strongest and most sustainable applications remain within the financial sector, emphasizing the need for robust, revenue-generating projects over speculative tokens.
  • 2. Leverage AI for Innovation: Startups that effectively integrate AI to solve real-world problems, particularly in personalized applications, are poised for significant growth and competitive advantage.
  • 3. Embrace Tokenization: The future of equity and capital formation lies in tokenizing shares and streamlining IPO processes on-chain, presenting a transformative opportunity for startups and investors alike.
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February 24, 2025

Solana’s Vibe Shift, Restaking, and Yapping About Kaito | Ian Unsworth

0xResearch

Crypto
DeFi
AI

Key Takeaways:

  • :
  • 1. Solana’s Dependence on Meme Coins: While meme coins drive substantial revenue for Solana, they also introduce significant vulnerabilities amid changing market sentiments and regulatory pressures.
  • 2. Staking Yield Dynamics: Proposed reductions in staking yields are unlikely to trigger mass unstaking but will push the ecosystem towards more liquid and innovative staking solutions.
  • 3. Kaido’s Tokenomics Potential: Emerging platforms like Kaido offer novel tokenomics and AI integration, presenting new opportunities and challenges in monetizing user engagement and attention.
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February 24, 2025

Memes are Dead, Long Live the Memes | Nick Tomaino

Empire

Crypto
DeFi

Key Takeaways:

  • :
  • 1. Meme coins, while initially promising, often exploit retail investors through pump and dump schemes, necessitating a wary approach.
  • 2. Investing in crypto requires a long-term vision, focusing on meaningful projects and founders committed to sustained growth over fleeting gains.
  • 3. Stablecoins are pivotal in maintaining the US dollar's global influence and are set to grow with increasing adoption and regulatory support.
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