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AI Podcasts

January 18, 2026

Why Every Brain Metaphor in History Has Been Wrong [SPECIAL EDITION]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The Strategic Pivot: The transition from "Understanding-First" science to "Prediction-First" engineering. We are building artifacts that work perfectly but remain theoretically opaque.
  2. The Tactical Edge: Audit your AI stack for "Leaky Abstractions." Don't assume a model's reasoning capabilities in one domain will hold when the underlying causal structure changes.
  3. AGI isn't just an engineering milestone; it's a philosophical wager. If the brain isn't a computer, we are building a very powerful helicopter, not a synthetic human.
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January 18, 2026

Why Every Brain Metaphor in History Has Been Wrong [SPECIAL EDITION]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The pivot from "Understanding-First" science to "Prediction-First" engineering creates massive technical liability in our models.
  2. Audit your AI implementations for "Leaky Abstractions" where the model fails to account for physical edge cases.
  3. High-performance automation is not the same as sentient reasoning. Builders who recognize this distinction will avoid the cultural illusion of inevitable AGI.
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January 17, 2026

Brex’s AI Hail Mary — With CTO James Reggio

Latent Space

AI
Key Takeaways:
  1. The transition from deterministic software to agentic networks. Companies are moving from rigid workflows to fluid systems that plan and execute autonomously.
  2. Build an internal LLM gateway early. Centralizing model routing and cost monitoring allows you to swap providers as the model horse race changes without refactoring your product.
  3. AI is not just a feature but a fundamental restructuring of the corporate cost center. Efficiency gains allow a static headcount of 300 engineers to support a business growing 5x.
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January 14, 2026

Identity for AI Agents - Patrick Riley & Carlos Galan, Auth0

AI Engineer

AI
Key Takeaways:
  1. The transition from interactive chat to autonomous "task runners" requires a shift from session-based identity to delegated, long-term authorization.
  2. Implement the Token Vault pattern to decouple your agent logic from the mess of OAuth token refreshing.
  3. In the next year, the "Agentic Web" will live or die by trust. If you cannot prove an agent is authorized to act, it is just a fancy toy.
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January 15, 2026

AI and the Future of Warfare with US Under Secretary of War Emil Michael

No Priors: AI, Machine Learning, Tech, & Startups

AI
Key Takeaways:
  1. The Macro Shift: The Great Re-Shoring. National security now depends on domestic production of critical minerals and semiconductors.
  2. The Tactical Edge: Build for Scale. Prioritize manufacturing competence over pure software features to win government contracts.
  3. The Bottom Line: The defense industrial base is being rebuilt from the ground up. The next decade belongs to the builders who can merge Silicon Valley speed with the Pentagon's scale.
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January 15, 2026

Ben & Marc: Why Everything Is About to Get 10x Bigger

a16z

AI
Key Takeaways:
  1. The transition from software eating the world to AI reinventing the computer means every existing market cap is a floor.
  2. Prioritize the non-fungible creator by providing monetization tools that bypass legacy gatekeepers.
  3. We are entering a period of asymmetric payoffs where the art of picking original thinkers matters more than historical data.
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January 13, 2026

Paul Rosolie: Uncontacted Tribes in the Amazon Jungle | Lex Fridman Podcast #489

Lex Fridman

AI
Key Takeaways:
  1. The Macro Trend: Biological Sovereignty. As global systems destabilize, the Amazon remains the most critical piece of biological infrastructure on the planet.
  2. The Tactical Edge: Support Jungle Keepers. Direct capital to organizations that convert loggers into rangers to secure land concessions.
  3. The Amazon is a finite asset under active siege. Protecting it requires a blend of primitive survival skills and high-tech surveillance over the next 18 months.
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January 12, 2026

Jensen Huang says robots will have human capabilities this year! The Robots at CES Had.. Other Plans

Turing Post

AI
Key Takeaways:
  1. The Macro Pivot: As generative AI masters simulation, the physical world becomes a high-fidelity playground for software.
  2. The Tactical Edge: Invest in the "brain" layer rather than the "limb" layer. Software that can generalize across different hardware forms will capture the most value.
  3. The next decade belongs to embodied AI that reasons in real time. If you are waiting for the hardware to look perfect before paying attention, you will miss the moment the software takes over the physical world.
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January 12, 2026

Your MCP Server is Bad (and you should feel bad) - Jeremiah Lowin, Prefect

AI Engineer

AI
Key Takeaways:
  1. The Macro Pivot: Context as Product. We are moving from raw data transport to opinionated context delivery.
  2. The Tactical Edge: Prune your endpoints. Remove any tool that requires more than one step to achieve a business result.
  3. The Bottom Line: The winners of the agentic era will be those who build the best Agentic Interface Guidelines.
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Crypto Podcasts

March 21, 2025

Crypto Is At An Inflection Point | Ryan Connor

Lightspeed

Crypto

Key Takeaways:

  • 1. The crypto market is at a pivotal moment, poised for a significant influx of institutional capital pending regulatory clarity.
  • 2. Incumbent players, particularly in Layer 1 blockchains and certain DeFi applications, are well-positioned to benefit from this growth.
  • 3. Stablecoins represent a profitable but competitive landscape, with opportunities for disruption as net interest margins get compressed.
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March 20, 2025

Data Deep Dive: Are Memecoins Dead? | Analyst Round Table

0xResearch

Crypto

Key Takeaways:

  • 1.  Memecoins, despite a decline in activity, are far from dead and continue to drive substantial revenue on several blockchains.
  • 2.  Solana faces challenges related to brand perception and governance mechanisms, highlighting the need for careful balancing of stakeholder interests.
  • 3.  The lines between DeFi and TradFi are blurring, with both sides vying for market share and experimenting with different partnership and competitive models.
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March 19, 2025

How Long Will This Bear Market Last? | EP 72

Good Game Podcast

Crypto

Key Takeaways:

  • 1. Despite short-term market volatility influenced by factors like tariff discussions, the underlying economy appears healthy, presenting a potentially bullish outlook for Bitcoin.
  • 2. RWA and Trafi represent significant growth areas in crypto, but the rationale behind permissioned blockchains needs further examination.
  • 3. AI continues to rapidly evolve, with vibe coding and localized LLMs poised to democratize app development and enhance user experiences.
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March 19, 2025

When Will Bitcoin Bottom?

1000x Podcast

Crypto

Key Takeaways:

  • 1. Bitcoin’s price is currently influenced more by macro factors than crypto-specific news.
  • 2. Altcoins are underperforming, presenting shorting opportunities for traders.
  • 3.  Focus on emerging trends like stablecoin growth and RWA tokenization for potential long-term gains.
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March 18, 2025

Joe McCann on Why Bitcoin Is the King and Memecoins Are Over—For Now

Unchained

Crypto

Key Takeaways:

  • 1. While the current landscape for meme coins and certain trading strategies seems saturated, innovation and new implementations will drive the next wave of opportunities.
  • 2. Macroeconomic forces, particularly institutional deleveraging, are significant drivers of recent market fluctuations, but long-term fundamentals remain strong for Bitcoin and select altcoins like Solana.
  • 3. The convergence of AI and crypto holds immense potential, with orchestration playing a key role in unlocking value and efficiency across various applications.
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March 18, 2025

Why Solana’s Inflation Proposal Didn’t Pass | Weekly Roundup

Lightspeed

Crypto

Key Takeaways:

  • 1. Solana's governance processes are still evolving, requiring careful consideration of community sentiment and communication strategies.
  • 2. The Solana Foundation’s delegation program is a critical area for evaluation and potential restructuring to address decentralization concerns.
  • 3. Ethereum faces crucial decisions regarding its L1 and L2 strategy, with scaling the L1 being essential for long-term value capture.
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