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AI Podcasts

December 13, 2025

Minimax M2 – Olive Song, MiniMax

AI Engineer

AI
Key Takeaways:
  1. **The "Small is Mighty" Paradigm:** Don't underestimate smaller, specialized models. M2 proves that smart engineering, real-world feedback, and iterative reasoning can outperform larger models in specific, high-value domains.
  2. **Builders, Embrace Iteration:** Design your agents with "interleaved thinking." The ability to self-correct and adapt to noisy environments is critical for real-world utility.
  3. **The "So What?":** The next wave of AI agents will be defined by their robustness, cost-effectiveness, and ability to generalize across dynamic environments. M2 is a blueprint for building practical, scalable AI that developers will actually integrate into their daily workflows.
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December 11, 2025

No Priors Ep. 143 | With ElevenLabs Co-Founder Mati Staniszewski

No Priors: AI, Machine Learning, Tech, & Startups

AI
Key Takeaways:
  1. Strategic Shift: The future of human-computer interaction is voice-first, moving from static content to dynamic, personalized, and agentic experiences.
  2. Builder/Investor Note: Defensibility in AI is increasingly found in deep product layers, specialized architectural breakthroughs (especially in audio), and robust ecosystems, not just raw model scale.
  3. The "So What?": Over the next 6-12 months, expect to see significant advancements in proactive AI agents, immersive media, and personalized education, with voice as the core interface.
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December 10, 2025

The Unicorn Founder Who Delegated Everything.

a16z

AI
Key Takeaways:
  1. The AI-Delegation Revolution is Here: Start experimenting with AI tools like ChatGPT for delegation now. The future involves proactive machine assistants deeply integrated into your workflow.
  2. Builders & Investors: Focus on "How to Delegate": The biggest constraint isn't finding assistants, but teaching clients how to delegate effectively. Tools and services that educate delegators will win.
  3. Reclaim Your Ambition: By offloading the mundane, you free up mental bandwidth to think bigger, pursue more ambitious goals, and ultimately, control your most valuable asset: time.
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December 12, 2025

AI Eats the World: Benedict Evans on the Next Platform Shift

a16z

AI
Key Takeaways:
  1. Strategic Implication: The AI bubble is inevitable. Focus on defensible positions: deep product integration, proprietary data, and distribution, rather than just raw model performance.
  2. Builder/Investor Note: The opportunity lies in productizing AI for specific "jobs to be done" within niche industries, creating intuitive UIs, and building in validation, not just building another foundational model.
  3. The "So What?": We're about to figure out the true "job to be done" for many industries. AI will unbundle existing businesses by exposing their hidden inefficiencies or non-obvious defensibilities.
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December 13, 2025

The Mathematical Foundations of Intelligence [Professor Yi Ma]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Embrace Parsimony and Self-Consistency: Adopt these principles as guiding forces in AI design. Build models that not only compress data efficiently but also maintain a high degree of self-consistency to ensure accurate and reliable world models.
  2. Focus on Abstraction, Not Just Memorization: Prioritize developing systems that can abstract knowledge beyond mere memorization. Move beyond surface-level compression and aim for models that can discover and reason about the underlying principles of the world.
  3. Understand and Reproduce the Brain’s Mechanisms: Focus on understanding and reproducing the mechanisms in the human brain that enable deductive reasoning, logical thinking, and the creation of new scientific theories to truly push AI to the next level.
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December 10, 2025

Nav Kumar: Trishool, AI Alignment, Subnet 23, Mechanistic Interpretability, Rogue LLMs | Ep. 75

Ventura Labs

AI
Key Takeaways:
  1. **Prioritize AI Safety Research:** Invest aggressively in understanding and mitigating AI risks to safeguard humanity against potential rogue LLMs.
  2. **Support Decentralized AI Alignment:** Champion decentralized platforms like Bit Tensor and initiatives like Trishool that promote open and transparent AI alignment research.
  3. **Embrace Mechanistic Interpretability:** Drive the development of tools that enable us to understand and control the internal workings of AI models, ensuring alignment with human values.
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December 10, 2025

Everyone Needs an Assistant. Here’s Why.

a16z

AI
Key Takeaways:
  1. Embrace Delegation as a Foundational Skill: Whether you leverage AI or human support, mastering delegation is paramount for unlocking personal and professional potential.
  2. Prioritize Time Ownership: Recognize time as your most valuable asset and design your life and calendar around your highest goals.
  3. Start Small, Scale Intentionally: Begin with affordable AI tools and gradually incorporate human assistance as your budget and needs evolve, building trust and compounding leverage over time.
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December 8, 2025

Building The Chip That Could Unlock AGI | Naveen Rao

a16z

AI
Key Takeaways:
  1. **Embrace Analog:** Explore and invest in analog computing solutions to overcome the energy limitations of current digital AI systems.
  2. **Prioritize Causality:** Shift focus towards AI models that incorporate time and causality, potentially unlocking more advanced and human-like intelligence.
  3. **Support Hardware Innovation:** Invest in and foster startups like Unconventional AI that are tackling fundamental challenges in AI hardware.
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December 8, 2025

Why AI Will Have To Run On Blockchains

The DCo Podcast

AI
Key Takeaways:
  1. Blockchain is essential for AI to ensure censorship resistance and uninterrupted accessibility.
  2. Trustworthy AI agents require on-chain governance to manage assets securely and transparently.
  3. AI agents can drastically accelerate blockchain adoption and optimize corporate processes.
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Crypto Podcasts

March 24, 2025

What It Takes To Build In Crypto | Stani Kulechov & Jack O'Holleran

Empire

Crypto

Key Takeaways:

  1. Building in crypto presents unique challenges related to novel tech, tokenomics, and community dynamics.
  2. Successful founders must balance long-term vision with the fast-paced, narrative-driven nature of the market.
  3. Capital efficiency is becoming increasingly important, with community fundraising offering a powerful alternative to traditional VC rounds.
  4. Crypto founders face a triple threat: building the product, managing tokenomics, and running a community like a rock band. Buckle up.
  5. Tokens can be a blessing and a curse.  Nail the community aspect and you’ve got a rocket. Mess it up and it’s a dumpster fire.
  6. Raise smart, not big. Find investors who get it, not just those who write checks.  Community rounds might be your secret weapon.
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March 24, 2025

Why Privacy Matters For Solana | Yannik Schrade

Lightspeed

Crypto

Key Takeaways:

  1. Archium represents a shift from basic transactional privacy to a more robust and versatile approach leveraging encrypted shared state, paving the way for complex applications on Solana.
  2. Archium’s stateless design and integration with Solana through CPI calls provide a seamless development experience and ensure efficiency.
  3. The Archium token incentivizes network participation and enables a dynamic supply and demand mechanism for computing power, while computations are paid for in SOL.
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March 21, 2025

Crypto Is At An Inflection Point | Ryan Connor

Lightspeed

Crypto

Key Takeaways:

  • 1. The crypto market is at a pivotal moment, poised for a significant influx of institutional capital pending regulatory clarity.
  • 2. Incumbent players, particularly in Layer 1 blockchains and certain DeFi applications, are well-positioned to benefit from this growth.
  • 3. Stablecoins represent a profitable but competitive landscape, with opportunities for disruption as net interest margins get compressed.
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March 20, 2025

Data Deep Dive: Are Memecoins Dead? | Analyst Round Table

0xResearch

Crypto

Key Takeaways:

  • 1.  Memecoins, despite a decline in activity, are far from dead and continue to drive substantial revenue on several blockchains.
  • 2.  Solana faces challenges related to brand perception and governance mechanisms, highlighting the need for careful balancing of stakeholder interests.
  • 3.  The lines between DeFi and TradFi are blurring, with both sides vying for market share and experimenting with different partnership and competitive models.
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March 19, 2025

How Long Will This Bear Market Last? | EP 72

Good Game Podcast

Crypto

Key Takeaways:

  • 1. Despite short-term market volatility influenced by factors like tariff discussions, the underlying economy appears healthy, presenting a potentially bullish outlook for Bitcoin.
  • 2. RWA and Trafi represent significant growth areas in crypto, but the rationale behind permissioned blockchains needs further examination.
  • 3. AI continues to rapidly evolve, with vibe coding and localized LLMs poised to democratize app development and enhance user experiences.
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March 19, 2025

When Will Bitcoin Bottom?

1000x Podcast

Crypto

Key Takeaways:

  • 1. Bitcoin’s price is currently influenced more by macro factors than crypto-specific news.
  • 2. Altcoins are underperforming, presenting shorting opportunities for traders.
  • 3.  Focus on emerging trends like stablecoin growth and RWA tokenization for potential long-term gains.
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