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AI Podcasts

December 31, 2025

[State of Research Funding] Beyond NSF, Slingshots, Open Frontiers — Andy Konwinski, Laude Institute

Latent Space

AI
Key Takeaways:
  1. The transition from monolithic models to compound systems means the value is migrating to the orchestration and context layer.
  2. Prioritize tools like DSPy and context management frameworks to build high-leverage applications that do not depend on proprietary model updates.
  3. Open research is the only way to maintain a competitive edge. If the US stops publishing, it stops leading.
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December 31, 2025

Infinity, Paradoxes, Gödel Incompleteness & the Mathematical Multiverse | Lex Fridman Podcast #488

Lex Fridman

AI
Key Takeaways:
  1. From Singular Logic to Pluralistic Systems. As we build complex AI, we must move from seeking one "correct" model to managing a multiverse of conflicting but internally consistent logical frameworks.
  2. Audit for Incompleteness. When designing protocols, identify the "independent" variables that your system cannot prove or settle internally.
  3. Truth is bigger than code. Over the next year, the winners will be those who stop trying to "solve" the universe and start navigating the multiverse of possible truths.
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December 31, 2025

AI in 2026: 3 Predictions For What’s To Come (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. Outcome-Based Intelligence. We are moving from AI as a Service to AI as an Outcome where value is tied to results rather than usage.
  2. Target Non-Public Data. Build applications in sectors like law or lending where the most valuable data is private and un-crawlable.
  3. The next two years will separate companies that use AI to save pennies from those that use AI to capture entire markets through autonomous systems and proprietary data loops.
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December 30, 2025

Your Brain Doesn't Command Your Body. It Predicts It. [Max Bennett]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The macro pivot: The transition from static data training to interactive world models that perform active inference.
  2. The tactical edge: Prioritize AI architectures that incorporate continual learning and hypothesis testing rather than just scaling parameters.
  3. The next decade belongs to those who replicate the biological transition from observation to interactive simulation.
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December 31, 2025

The Algorithm That IS The Scientific Method [Dr. Jeff Beck]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The Macro Transition: Move from Big Data mimicry to Small Data causal reasoning.
  2. The Tactical Edge: Prioritize Active Inference frameworks that track uncertainty.
  3. AGI won't come from bigger LLMs; it will come from agents that possess a physics-grounded world model.
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December 30, 2025

[State of AI Startups] Memory/Learning, RL Envs & DBT-Fivetran — Sarah Catanzaro, Amplify

Latent Space

AI
Key Takeaways:
  1. The transition from stateless chat interfaces to stateful, personalized agents that learn from every interaction.
  2. Prioritize memory. If you are building an application, treat state management and continual learning as your core technical moat to prevent user churn.
  3. Stop chasing clones of existing apps for reinforcement learning. Use real-world logs and traces to build models that solve actual engineering friction.
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December 30, 2025

[State of RL/Reasoning] IMO/IOI Gold, OpenAI o3/GPT-5, and Cursor Composer — Ashvin Nair, Cursor

Latent Space

AI
Key Takeaways:
  1. The transition from internet-scale imitation to environment-scale RL.
  2. Build products that capture the full context of a professional's workflow to make them RL-ready.
  3. Intelligence is no longer the bottleneck. The winner will be whoever builds the best hard drive for professional context.
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December 31, 2025

[State of Post-Training] From GPT-4.1 to 5.1: RLVR, Agent & Token Efficiency — Josh McGrath, OpenAI

Latent Space

AI
Key Takeaways:
  1. The Macro Pivot: Intelligence is moving from a scarce resource to a commodity where the primary differentiator is the cost per task rather than raw model size.
  2. The Tactical Edge: Prioritize building on models that demonstrate high token efficiency to ensure your agentic workflows remain profitable as complexity grows.
  3. The Bottom Line: The next year will be defined by the systems vs. models tension. Success belongs to those who can engineer the environment as effectively as the algorithm.
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December 31, 2025

[State of Evals] LMArena's $100M Vision — Anastasios Angelopoulos, LMArena

Latent Space

AI
Key Takeaways:
  1. The transition from static benchmarks to "Vibe-as-a-Service" means model labs must optimize for human delight rather than just loss curves.
  2. Use Arena’s open-source data releases to fine-tune models on real-world prompt distributions.
  3. In a world of synthetic data and benchmark saturation, human preference is the only remaining scarce resource for validating frontier capabilities.
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Crypto Podcasts

May 21, 2025

The REV Debate: Real Metric or Fake News? Jon, Bread, & Andy8052

Bankless

Crypto
Key Takeaways:
  1. REV is a starting point, not the finish line: It's a useful, objective measure of immediate user willingness to pay for blockspace but doesn't encompass all value drivers of an L1.
  2. App-layer eats L1 lunch (eventually): Expect applications to get better at internalizing value (like MEV), potentially reducing direct REV flow to L1s, making app success crucial for the L1 ecosystem.
  3. Narrative & adoption still trump pure metrics: For now, perceived momentum, user growth, and developer activity (like on Solana) can heavily influence L1 valuations, often overshadowing strict adherence to metrics like REV multiples.
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May 21, 2025

The Solana Treasury Strategy

Lightspeed

Crypto
Key Takeaways:
  1. Investing in specialized crypto treasury vehicles offers exposure not just to the underlying asset but also to a strategy of active accumulation and yield enhancement. These companies argue their NAV premiums are justified by their operational capabilities and future growth prospects.
  2. NAV Premiums Signal Future Growth: Market premiums on crypto-holding companies often reflect expectations of continued asset accumulation, not just current asset values.
  3. Expertise Drives Alpha: Specialized operational capabilities, like in-house validator management, can generate significantly higher yields (20-40% more) than readily available retail options.
  4. Sophisticated Strategies Outperform Simple Holding: For investors seeking optimized exposure, vehicles offering complex, managed strategies for asset accumulation and yield can provide an edge over direct, passive investment.
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May 20, 2025

The Microstrategy Of Solana Playbook With Dan Kang

Lightspeed

Crypto
Key Takeaways:
  1. Beyond ETFs: These treasury vehicles offer a more dynamic, potentially higher-return (and higher-risk) path to crypto exposure than standard ETFs, focusing on active accumulation and yield enhancement.
  2. Volatility as a Tool: For certain crypto-native companies, extreme stock volatility is actively cultivated to unlock unique capital market opportunities and attract specific investor demographics.
  3. The Solana "MicroStrategy" Model is Live: Companies like DeFi DevCorp are demonstrating that the playbook of leveraging public markets for aggressive, single-asset crypto accumulation can be replicated beyond Bitcoin, with Solana as a prime new candidate.
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May 20, 2025

Bits + Bips LIVE - May 19th, 2025

Unchained

Crypto
Key Takeaways:
  1. Tariffs Trump Tranquility: A 10% tariff floor could trigger summer stagflation, disrupting current Goldilocks market pricing.
  2. Stablecoin Bill is Bellwether: The fate of the "Genius Act" will significantly impact the trajectory of broader US crypto regulation and investor confidence.
  3. Institutional Crypto Evolves: Coinbase's S&P 500 nod and the push for diverse crypto ETFs (like Solana) underscore the sector's maturation, even as regulatory hurdles for features like staking persist.
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May 19, 2025

The State of Venture Today | Roundup Clip

Bell Curve

Crypto
Key Takeaways:
  1. LP Scrutiny Intensifies: Expect smaller fundraises for many VCs, especially in crypto, as LPs demand real returns (DPI) and, for crypto, regulatory certainty.
  2. Endowment Exodus Looms: Yale's $6B private equity sale signals a potential LP supply shock as other endowments may follow suit due to tax changes and liquidity needs.
  3. Elite VCs Consolidate Power: Capital will increasingly flow to the top 5-10 VC firms, particularly those with AI expertise, hastening the decline of underperformers.
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May 19, 2025

The Bull Case For Ethereum | Ryan Berckmans & Tom Dunleavy

Empire

Crypto
Key Takeaways:
  1. ETH's Valuation Paradigm Shift: Value ETH based on Total Value Secured (TVS), not diminishing transaction fees, as it aims to secure trillions in global assets.
  2. L1+L2 is the Winning Formula: Ethereum's strategy of scaling L1 alongside a diverse L2 ecosystem (offering political/business model diversity) is designed to onboard the world.
  3. Coordination & BD are Crucial: Renewed focus on cohesive narrative, business development (like Etherealize), and community alignment are vital to executing Ethereum's ambitious roadmap.
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