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AI Podcasts

May 30, 2025

Novelty Search May 29, 2025

taostats

AI
Key Takeaways:
  1. Democratization Unleashed: Subnet 17 radically lowers barriers to 3D content creation, empowering indie developers and non-artists.
  2. Gaussian Splats are Hot: This representation is emerging as a key technology for fast, high-fidelity 3D AI, and Subnet 17 is at the forefront.
  3. Web2 Validation is Key: Partnerships like the Unity "verified solution" status signal BitTensor's growing real-world utility and credibility, presenting opportunities for miners and the TAO ecosystem.
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May 30, 2025

SN17 - 404GEN :: Decentralized AI generated 3D assets

Opentensor Foundation

AI
Key Takeaways:
  1. Unlocking Creative Potential: 404GEN radically lowers barriers to 3D content creation, enabling faster iteration and new forms of interactive media previously unfeasible for smaller teams or individuals.
  2. Gaussian Splats are Ascendant: This representation is emerging as a powerful alternative for 3D AI, and 404GEN is at the forefront of its practical application and tooling.
  3. BitTensor's Competitive Edge Shines: The subnet's rapid quality improvement and the innovative ELO validation system highlight BitTensor's power to incentivize and coordinate decentralized intelligence towards state-of-the-art results.
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May 30, 2025

Hey Tech, Come to Healthcare

a16z

AI
Key Takeaways:
  1. **Build for Behavior Change:** The biggest wins will come from engaging consumers and enabling sustainable health behaviors, an area where tech excels.
  2. **AI is the Leapfrog:** Healthcare can jump directly to AI-driven solutions, bypassing clunky legacy software, especially for service-oriented tasks.
  3. **The Trillion-Dollar Prize is Real:** Whether through full-stack "payvider" models or horizontal platforms, the path to becoming the world's largest company runs through transforming the consumer healthcare experience.
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May 29, 2025

Building a DePIN-powered Shazam for Media with Rumi | Niko Cunningham and Mateusz Poreda

Proof of Coverage Media

AI
Key Takeaways:
  1. **Decentralized Analytics:** Rumi’s DePIN model democratizes media intelligence, offering far richer and more granular data than traditional players like Nielsen.
  2. **Context is King:** The "Shazam for media" capability will fuel a new generation of AI agents and interactive experiences, making media deeply engaging.
  3. **Investor Signal:** The $5M pre-seed (EV3, A16Z CSX) and early traction with industry players like Tivision validate Rumi's approach and market potential.
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May 29, 2025

Beyond Leaderboards: LMArena’s Mission to Make AI Reliable

a16z

AI
Key Takeaways:
  1. Reliability Demands Real-Time, Human-Centric Testing: Static benchmarks are dead. AI reliability for complex tasks requires continuous evaluation based on diverse, subjective human preferences in real-world scenarios.
  2. Crowd-Sourced Evaluation Outperforms Insular Expertise: The "wisdom of the crowd," as captured by LMArena, provides a more robust and representative measure of AI performance than siloed expert opinions, preventing narrow value-encoding.
  3. Personalized Evaluation is the Next Frontier: Technologies like "Prompt to Leaderboard" show the potential for highly granular, cost-effective, and personalized AI model selection, maximizing utility for individual users and specific tasks.
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May 28, 2025

Rick Rubin: Vibe Coding is the Punk Rock of Software

a16z

AI
Key Takeaways:
  1. Embrace AI as a Co-Creator: Leverage AI to democratize creation and rapidly iterate, but remember the unique human element—your distinct point of view and intuition—is irreplaceable.
  2. Authenticity Over Algorithm: Whether you're an artist or an entrepreneur, genuine connection comes from unwavering commitment to your core vision, not by chasing fleeting trends or assumed audience desires.
  3. Question Everything, Especially "Answers": Cultivate a mindset of curiosity and critical thinking. AI can provide answers, but true insight comes from deeply engaging with questions and understanding that knowledge is ever-evolving.
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May 27, 2025

7 More Healthy Years: What We Can Learn from Super Agers

a16z

AI
Key Takeaways:
  1. Embrace AI-Powered Prevention: AI's capacity to synthesize vast health data will redefine personalized risk assessment and early intervention, moving us beyond one-size-fits-all healthcare.
  2. Target the "Big Three" Early: Focus on preventing cancer, cardiovascular disease, and neurodegenerative conditions by leveraging their long incubation periods for proactive interventions.
  3. Leverage New Therapeutic Frontiers: Groundbreaking drug classes like GLP-1s and rapid advancements in immunotherapy offer unprecedented tools to combat and, crucially, prevent major diseases.
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May 27, 2025

TAOFU's Mikel & Mitch: Enabling Capital Formation for Subnets on Bittensors $10B+ Network

Delphi Digital

AI
Key Takeaways:
  1. Democratized Subnet Funding: TAOFU’s SNS model allows subnet creators to raise capital without diluting their core emission-earning potential, fostering more shots on goal for AI innovation on Bittensor.
  2. Investor Access & Liquidity: For investors, TAOFU provides a clear mechanism (SNS tokens and an integrated DEX) to invest in early-stage Bittensor subnets and gain liquidity, previously a closed-off and opaque process.
  3. Curated Quality: TAOFU’s permissioned approach and focus on sustainable value capture (with plans for a curator model) aim to filter for high-quality projects, protecting investors while nurturing promising AI ventures within Bittensor.
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May 26, 2025

Has AI Revived the DePIN Sector? | Dmitriy Berenzon

0xResearch

AI
Key Takeaways:
  1. AI is DePIN's Demand Catalyst: The need for affordable AI compute is breathing new life and tangible demand into decentralized infrastructure.
  2. Value Accrual & Revenue are King: For DePIN tokens to thrive in liquid markets, clear mechanisms for value flow-through from opco revenue to the token are non-negotiable; "ARR is the new TVL."
  3. Distribution Trumps Decentralization (for now): Crypto-native solutions, especially in payments, must crack the distribution code or risk being outmaneuvered by Web2 incumbents leveraging their massive user bases.
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Crypto Podcasts

June 13, 2025

0xResearch | Friday, June 13th

0xResearch

Crypto
Key Takeaways:
  1. **Meme Wisely:** ETH's narrative power is potent, but sustainable value needs a bedrock of technological strength and real-world utility.
  2. **Stablecoins are King:** This is the crypto sector attracting serious institutional capital and big tech attention; the growth runway is immense.
  3. **Regulation is Warming:** Positive signals from the SEC on self-custody and staking offer tailwinds, potentially de-risking significant parts of the crypto ecosystem.
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June 13, 2025

Takeaways from the SEC Roundtable and Privy Acquisition | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Regulatory Thaw: The SEC’s new leadership signals a more accommodating stance on crypto, potentially unlocking significant growth for DeFi in the US.
  2. Market Structure Evolution: Tokenization is increasingly viewed as the key to modernizing capital markets, with on-chain IPOs and improved secondary market liquidity on the horizon.
  3. Infrastructure is King: Acquisitions like Privy by Stripe highlight the race to build and control the foundational layers of the crypto economy, especially around wallets and stablecoins.
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June 13, 2025

Institutions Pour Billions into Crypto! Stripe’s Bold Move & Genius Act Explained

Bankless

Crypto
Key Takeaways:
  1. Institutional FOMO is Real: Bitcoin and Ethereum ETFs are magnets for capital, and Circle's IPO success signals massive pent-up demand.
  2. Regulation is Maturing: The Genius Act is poised to legitimize stablecoins, while the Clarity Act could reshape token classifications.
  3. Adoption Accelerates: Stripe's crypto acquisitions and Poly Market's X integration show crypto moving beyond niche use cases.
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June 13, 2025

Standard Chartered: The Bull Case For Solana | Geoff Kendrick

Lightspeed

Crypto
Key Takeaways:
  1. Solana's Next Act is Crucial: Current memecoin activity, while impressive, is viewed by institutions like Standard Chartered as less sustainable than diversified utility; a pivot to tokenized equities or social is key for long-term valuation.
  2. Perception Battles Performance: Ethereum's established "trustworthiness" gives it an institutional edge, even if Solana offers superior tech for certain applications. Solana must overcome its "memecoin" image to attract serious TradFi.
  3. Near-Term Headwinds for Solana Relative to Ethereum: Kendrick suggests Ethereum might outperform Solana in the near term (though both underperform Bitcoin) as Solana navigates its transition phase, while Ethereum benefits from incumbency in stablecoins and tokenized RWAs.
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June 12, 2025

The Digital Payment Race That Will Reshape the World

Forward Guidance

Crypto
Key Takeaways:
  1. **Currency Cold War:** A "currency conflict" is unfolding, with the winner set to define the financial backbone of the next-gen internet and global commerce.
  2. **Stablecoins vs. The State:** USD stablecoins are pitched as the West's best bet for the internet's future currency, directly competing with state-backed digital currencies like China's e-CNY.
  3. **Agent-Powered Internet:** The dream is an internet where AI agents, fueled by ultra-low-cost stablecoin transactions, manage our digital lives, moving incentives away from human attention.
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June 12, 2025

The Last Mile Problem For Stablecoins | Analyst Round Table

0xResearch

Crypto
Key Takeaways:
  1. **Solve Real Friction:** The "last-mile" challenge—seamlessly converting stablecoins to local cash in emerging markets—remains the critical bottleneck and prime opportunity for stablecoin protocols.
  2. **Moats are Real:** Overcoming established players like Tron requires more than just better tech or lower fees; it demands superior distribution and user migration strategies.
  3. **Align Incentives:** Morpho's structural changes offer a compelling model for aligning team, investor, and token holder interests, potentially setting a new standard for Web3 projects.
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