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AI Podcasts

July 31, 2025

China Open-Source, Compute Arms Race, Reordering Global Trade | BG2 w/ Bill Gurley and Brad Gerstner

Bg2 Pod

AI
Key Takeaways:
  1. China's Open-Source Models are Winning on Price & Performance. Chinese models offer ~90% of the intelligence of top US proprietary models for a fraction of the cost, driving massive global adoption and threatening to commoditize the model layer. An American open-source champion is desperately needed to compete.
  2. The "Cost is No Object" Compute Buildout is Reshaping the Market. A handful of private companies are spending at a loss to capture market share, fueled by VC. This creates a "sport of kings" dynamic that public companies can't match and makes pick-and-shovel players like Nvidia the biggest winners.
  3. The US Tariff Strategy is Working. Contrary to consensus, the administration's tariff gambit has secured favorable trade deals with the EU and Japan, generating hundreds of billions in revenue without causing significant consumer inflation, and setting the stage for a major renegotiation with China.
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July 31, 2025

Health Tech Founders: The Future of Care Is Personalized, Proactive—and AI-Powered

a16z

AI
Key Takeaways:
  1. Biology is the ultimate API for AI. The most impactful AI will be fed not just digital data but real-world biological signals. Companies are building the infrastructure to bring a user's biology online, turning abstract health data into a constant, actionable feed.
  2. Engagement metrics are being rewritten. Forget Daily Active Users. The new model is "intense, intentional engagement" during periods of need. Growth is a function of trust and real-world impact, where the best champions are users who have been genuinely helped.
  3. AI's role is augmentation, not automation. The goal isn't to replace doctors or therapists but to empower them. By translating noise into signal, AI lets human experts skip the data-sifting and focus on what they do best: solving problems.
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July 30, 2025

AI Content and the War for Your Attention

a16z

AI
Key Takeaways:
  1. AI is an attention-polluting machine. The primary challenge for social platforms will soon be managing the tidal wave of AI-generated "slop" designed to hijack algorithms, which risks alienating users entirely.
  2. The future of social is private. The psychological burden of being a micro-celebrity in a digital panopticon is pushing users away from public feeds and into smaller, trusted, and often monetized group chats.
  3. Attention mining’s endgame is total immersion. With phones saturated, the commercial logic of adtech demands new frontiers. VR is the path to monetizing waking hours, and Neuralink is the one to monetize dreams.
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July 30, 2025

Hash Rate - Ep 124 - Backprop / Tensorplex / Dojo (sn52) $TAO

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI
Key Takeaways:
  1. Trading is Training. Every dTAO trade is a direct vote on the value of an AI service, making traders active participants in steering the Bittensor network's intelligence and resource allocation.
  2. Human Feedback is the Moat. To advance, frontier AI needs subjective human preference data. Decentralized systems like Dojo (SN52) can provide this at scale, creating a crucial data pipeline that can’t be easily replicated.
  3. Predictability Breeds Value. The most successful decentralized networks (like Bitcoin) thrive on trust and predictability. Subnets that arbitrarily change rules risk alienating their miners and undermining the long-term health of the entire ecosystem.
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July 29, 2025

Will Squires & Chris Zacharia: Macrocosmos Bittensor Subnet 13, Data Scraping, AI Training | Ep. 54

Ventura Labs

AI
Key Takeaways:
  1. Macrocosmos is transforming Subnet 13 from a brute-force data scraper into a sophisticated, revenue-generating marketplace that serves as a foundational utility for the entire Bittensor ecosystem. Their core advice to the ecosystem is to relentlessly pursue real-world market validation over passively collecting protocol emissions.
  2. Data is the New Oil, Subnet 13 is the Rig: With 55 billion rows scraped, Subnet 13 is the de facto data layer for Bittensor, providing the essential fuel for everything from AI model training to real-time sentiment analysis for other subnets.
  3. From Raw Scale to Refined Value: The focus is shifting from merely scraping data to making it accessible. The upcoming "Data Universe" marketplace aims to be a "Bittensor Hugging Face," turning a chaotic data ocean into a library of actionable insights.
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July 28, 2025

Balaji Srinivasan: How AI Will Change Politics, War, and Money

a16z

AI
Key Takeaways:
  1. **Embrace Polytheism, Not Monotheism.** The future contains many culturally-specific, specialized AIs, not one superintelligence. The "war of the gods" is a more apt metaphor than a single, all-powerful deity.
  2. **Crypto is AI's Anchor to Reality.** As AI generates infinite probabilistic fakes, crypto's deterministic, on-chain data becomes the gold standard for verifiable truth in finance, media, and beyond.
  3. **The Real AI Threat is Physical, Not Persuasive.** Forget rogue chatbots. The immediate danger is autonomous drones, which are already transforming warfare and turning digital firewalls into hard, physical borders.
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July 28, 2025

James Woodman & Joshua Brown: Targon, Manifold Labs, Bittensor Subnet 4, Compute Markets | Ep. 53

Ventura Labs

AI
Key Takeaways:
  1. Price Discovery is the Product: Targon's auction mechanism isn't just a feature; it's the core product. By forcing compute providers to bid for their payout, the system creates a hyper-competitive environment that reveals the true, market-driven price of compute, incentivizing efficiency and driving costs down.
  2. The Race for Organic Revenue: The entire model hinges on achieving "escape velocity" where organic revenue from inference clients outpaces the reliance on network emissions. With $52,000 returned to the subnet in just eight days, they are proving the model works, but scaling this revenue is the central challenge.
  3. The Future is Financialized Compute: The end goal extends far beyond simply renting out GPUs. By establishing a liquid spot market, Targon is laying the groundwork to introduce financial derivatives like forward contracts and options, allowing enterprises to hedge against compute price volatility just as they do with other commodities.
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July 26, 2025

Intelligence = Doing More with Less (David Krakauer)

Machine Learning Street Talk

AI
Key Takeaways:
  1. Redefine Your Metrics. Judge intelligence not by what a system knows, but by its resourcefulness—its ability to solve novel problems with minimal information.
  2. Demand Deeper Proof. Don't accept claims of "emergence" based on performance charts. Look for evidence of a representational phase shift—a simpler, more abstract model of the world forming inside the machine.
  3. Think for Yourself. Resist the powerful urge to outsource your thinking to AI. Actively using your cognitive "muscles" is the only defense against the atrophy that convenience culture promotes.
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July 26, 2025

Bittensor Brief #2: VoidAI Wrapped TAO & Subnet Tokens

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI
Key Takeaways:
  1. Arbitrage Unlocked: The bridge exposes deeply undervalued Bittensor subnet tokens to the Solana ecosystem, creating a direct pathway to capture the 100x-1000x valuation gap between on-chain and off-chain AI projects.
  2. Incentivized Liquidity: Don’t be deterred by low initial liquidity. VoidAI's Subnet 106 is purpose-built to reward liquidity providers, creating a powerful economic engine designed to bootstrap and sustain deep markets for wrapped Bittensor assets.
  3. AI Meets DeFi: Wrapped TAO and subnet tokens can now be plugged into any Solana DeFi protocol. This opens a new frontier for financial products, allowing users to lend, borrow, and build derivatives on top of assets powered by a decentralized machine intelligence network.
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Crypto Podcasts

April 14, 2025

Bits + Bips LIVE

Unchained

Crypto
Key Takeaways:
  1. Headline Risk Reigns: Forget fundamentals for now. Market direction hinges almost entirely on White House pronouncements and tariff developments; consistency is desperately needed to restore confidence.
  2. Liquidity is King (and Scarce): Thin markets amplify moves. Watch ETF volumes (over 35% signals stress) and hedge fund positioning (currently defensive, fuel for squeezes) for tactical clues.
  3. Crypto's Macro Moment Deferred?: While geopolitics boosts crypto's *raison d'être* as a non-state asset, it needs a clearer macro picture or strong regulatory/product catalysts to break free from its current risk-asset correlation. Watch the Yuan/USD rate for capital flight signals.
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April 14, 2025

Bringing the World’s Vehicles Onchain with DIMO | Rob Solomon

Proof of Coverage Media

Crypto
Key Takeaways:
  1. Real Utility Drives Adoption: DIMO focuses on tangible benefits (cashback for data, vehicle tracking) beyond token speculation, making the platform sticky for everyday users.
  2. Tokenomics Power the Ecosystem: The $DIMO token is integral, used by developers for data access, with a burn mechanism creating deflationary pressure tied directly to network usage and revenue growth.
  3. Decentralization is the Moat: Building onchain provides a crucial advantage over closed ecosystems, ensuring user control, preventing platform risk, and attracting developers wary of centralized gatekeepers.
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April 14, 2025

The Biggest Market Crash Since 2020, What Next?

Forward Guidance

Crypto
Key Takeaways:
  1. Volatility is the New Normal: Brace for sustained higher volatility; cash and defensive positioning (energy, industrials) are prudent.
  2. Bitcoin's Moment? BTC is increasingly viewed as a macro hedge against instability and potential Fed easing, likely outperforming most alts.
  3. Policy Matters: Deficit reduction, trade wars, and Fed reactions are driving markets; understanding the administration's long-term goals (per Bessent) is crucial.
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April 14, 2025

Building the Future of Global Payments | Paul & Zaheer

0xResearch

Crypto
Key Takeaways:
  1. Specialization Wins: General-purpose blockchains struggle to optimally serve the massive, specific needs of stablecoin transfers; dedicated infrastructure like Plasma is required to unlock the next phase of growth.
  2. USDT is the Global Standard: Tether's dominance, especially outside the US, mirrors the Eurodollar system. It's the Schelling point for international digital dollars, unlikely to be displaced by domestic-focused or bank-issued alternatives.
  3. Focus on Fundamentals: Plasma bets on core utility (cheap/free, fast, secure transfers) and deep integrations over complex tokenomics, aiming to capture trillions in real-world commerce settlement.
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April 14, 2025

The Biggest Market Crash Since 2020, What Next? | Felix Jauvin & Quinn Thompson

Empire

Crypto
Key Takeaways:
  1. Valuations & Policy Collide: Overly optimistic markets hit a wall of peak valuations, expiring liquidity, and initially growth-negative policies.
  2. Bitcoin vs. The World: Bitcoin's near-term strength is tied to potential forced central bank liquidity, while major upside requires a breakdown in traditional fiscal/monetary stability. Prioritize BTC over most alts.
  3. Cash & Caution: Elevated volatility persists. Holding cash and focusing on resilient sectors (e.g., critical resources, energy) is prudent while navigating potential deleveraging events and geopolitical risks.
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April 11, 2025

Crypto Meets Chemistry :: Bittensor SN68 NOVA, Decentralized AI Drug Discovery

Opentensor Foundation

Crypto
Key Takeaways:
  1. Adversarial Advantage: Bittensor's miners are exceptionally efficient at finding flaws in AI models, turning a potential vulnerability into a powerful, real-time stress-testing mechanism crucial for robust drug discovery AI.
  2. Incentivizing Innovation: Token emissions provide funding and incentives for tackling high-risk, high-reward drug discovery challenges that traditional models struggle to support, fostering novelty over incrementalism.
  3. Digital-to-Physical Bridge: Nova plans to translate computational discoveries into real-world value through synthesis, lab validation, and strategic partnerships, aiming to become a pioneering crypto-native biotech entity.
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