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AI Podcasts

January 15, 2026

Ben & Marc: Why Everything Is About to Get 10x Bigger

a16z

AI
Key Takeaways:
  1. The transition from software eating the world to AI reinventing the computer means every existing market cap is a floor.
  2. Prioritize the non-fungible creator by providing monetization tools that bypass legacy gatekeepers.
  3. We are entering a period of asymmetric payoffs where the art of picking original thinkers matters more than historical data.
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January 13, 2026

Paul Rosolie: Uncontacted Tribes in the Amazon Jungle | Lex Fridman Podcast #489

Lex Fridman

AI
Key Takeaways:
  1. The Macro Trend: Biological Sovereignty. As global systems destabilize, the Amazon remains the most critical piece of biological infrastructure on the planet.
  2. The Tactical Edge: Support Jungle Keepers. Direct capital to organizations that convert loggers into rangers to secure land concessions.
  3. The Amazon is a finite asset under active siege. Protecting it requires a blend of primitive survival skills and high-tech surveillance over the next 18 months.
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January 12, 2026

Jensen Huang says robots will have human capabilities this year! The Robots at CES Had.. Other Plans

Turing Post

AI
Key Takeaways:
  1. The Macro Pivot: As generative AI masters simulation, the physical world becomes a high-fidelity playground for software.
  2. The Tactical Edge: Invest in the "brain" layer rather than the "limb" layer. Software that can generalize across different hardware forms will capture the most value.
  3. The next decade belongs to embodied AI that reasons in real time. If you are waiting for the hardware to look perfect before paying attention, you will miss the moment the software takes over the physical world.
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January 12, 2026

Your MCP Server is Bad (and you should feel bad) - Jeremiah Lowin, Prefect

AI Engineer

AI
Key Takeaways:
  1. The Macro Pivot: Context as Product. We are moving from raw data transport to opinionated context delivery.
  2. The Tactical Edge: Prune your endpoints. Remove any tool that requires more than one step to achieve a business result.
  3. The Bottom Line: The winners of the agentic era will be those who build the best Agentic Interface Guidelines.
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January 12, 2026

OpenAI + @Temporalio : Building Durable, Production Ready Agents - Cornelia Davis, Temporal

AI Engineer

AI
Key Takeaways:
  1. The industry is moving from "Agent as a Script" to "Agent as a Durable Service" where state management is handled by the infrastructure.
  2. Wrap your existing API tools in the `activity_as_tool` function to gain automatic retries and execution history.
  3. Reliability is the only moat in the agentic economy. If your agent cannot survive a server restart during a three-day task, it is not ready for the enterprise.
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January 13, 2026

How Ladder Became #1 Strength Training App

Invest Like The Best

AI
Key Takeaways:
  1. The Macro Trend: The move from fragmented content libraries to integrated health systems where AI synthesizes biomarkers and movement.
  2. The Tactical Edge: Construct internal LLM tools to categorize qualitative feedback. This turns thousands of raw reviews into a precise roadmap.
  3. The Bottom Line: Building a $100M ARR consumer app requires mastery of both growth loops and product retention. Solve for the daily habit to win the long game.
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January 13, 2026

Ben Horowitz on Investing in AI: AI Bubbles, Economic Impact, and VC Acceleration

a16z

AI
Key Takeaways:
  1. The transition from general-purpose AI to specialized application layers. As foundation models commoditize, value migrates to the "fat tail" of human-centric complexity.
  2. Prioritize building or investing in "DNA of the future" companies that incumbents must eventually acquire to survive. Focus on winning the "point of attack" by staying deep in the technical details.
  3. We are in a unique market where demand growth justifies high valuations. Success over the next year depends on identifying founders who are the absolute best in the world at one specific thing.
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January 13, 2026

It's Time To Build

a16z

AI
Key Takeaways:
  1. The Macro Shift: Infrastructure Invisibility. As core technologies become background noise, value moves from the pipes to the unique experiences built on top of them.
  2. The Tactical Edge: Reject Mediocrity. Audit your product for average features and replace them with high-conviction improvements that competitors are too lazy to attempt.
  3. The Bottom Line: Building is the only way to ensure the future happens. If you do not create the next version of reality, you are stuck living in an outdated vision.
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January 13, 2026

Nothing’s Carl Pei on Building a $1B Smartphone Company and Why He Thinks About Death Every Week

The Generalist

AI
Key Takeaways:
  1. The transition from hardware specs to emotional hardware where brand identity and OS-native AI become the primary moats.
  2. Prioritize arbitrage opportunities in marketing by finding underpriced attention on platforms like TikTok before they become crowded.
  3. Success in mature markets requires a Genghis Khan method: be a talent scout, stay open-minded to global supply chains, and use design to win the emotional battle for the consumer's pocket.
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Crypto Podcasts

July 12, 2025

How PumpDotFun Could Capture The Intersection Of Content, Crypto And Gaming

Empire

Crypto
Key Takeaways
  1. The New Media Blueprint: The winning strategy is a blend of long-form, authentic live streams and hyper-optimized social clips. Platforms that natively support this will win.
  2. Content, Not Just Coins: To achieve longevity, Pump.fun must evolve beyond a pure trading terminal. It needs to give users a reason to stay that isn't just watching a chart.
  3. Finance Is Entertainment: For a new generation, trading is a competitive social game. The most successful platforms will be those that embrace this "leaderboard" mentality and build entertainment-first financial experiences.
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July 12, 2025

Phantom Chooses Hyperliquid for Perps | 0xResearch

0xResearch

Crypto
Key Takeaways:
  1. Distribution is the New Moat: Wallets like Phantom are becoming aggregator kings. By integrating the best backend protocol (Hyperliquid), they can dominate user flow and marginalize competing applications.
  2. Infrastructure Eats Applications: Hyperliquid’s success stems from its focus on being a permissionless infrastructure layer, not just an app. It outsources distribution to capture flow from the entire crypto ecosystem, a model that standalone DEXes will find nearly impossible to compete with.
  3. Mobile is Crypto’s Next Frontier: Phantom’s mobile-only perp launch is a bet that the next wave of users will prioritize convenience and native experiences. Its initial success signals a critical shift in how DeFi applications must be designed and delivered.
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July 11, 2025

Winners & Losers From PUMP’S ICO With Santi & Rob Hadick | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. **App-Chains Are The New End Game.** Successful apps are now launching their own sovereign chains, posing an existential threat to host L1s like Solana. The most valuable real estate is direct user ownership, not just building on the fastest chain.
  2. **Trading Is The New Gaming.** For Gen Z, speculation is a primary form of entertainment. Platforms that successfully blend content with financialization are tapping into a powerful cultural current that moves far beyond traditional "investing" narratives.
  3. **Winners Buy, They Don't Build.** The crypto M&A market is hot. Well-capitalized players (e.g., Monad buying Portal) are acquiring talent and tech to build full-stack platforms, while many 2022-era startups are prime acquisition targets.
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July 11, 2025

Bitcoin All-Time-High, Is ETH Next?

Bankless

Crypto
Key Takeaways:
  1. A perfect storm of narrative, structural demand, and historical precedent is building for Ether, but its price has yet to reflect this reality, and the underlying technical work remains critical.
  2. The ETH Coiled Spring: A massive disconnect exists between euphoric pro-ETH sentiment—driven by treasury buys and mainstream narratives—and its lagging price. History suggests when ETH moves, it will be explosive, leaving sideline-sitters behind.
  3. Corporate Treasuries are the New Demand Sink: A new class of publicly traded "ETH Treasury" companies is in an arms race to acquire ETH, creating a structural demand shock that could absorb all new issuance and initiate a powerful positive feedback loop.
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July 10, 2025

The 8% Debasement Trap Killing Your Wealth

Forward Guidance

Crypto
Key Takeaways:
  1. Your Portfolio Is Bleeding. Unless concentrated in tech (NASDAQ) and crypto (Bitcoin, ETH), your purchasing power is eroding by 8% annually. Assets like the S&P 500 or gold are merely treading water against this relentless tide.
  2. Diversification Is a Wealth Destroyer. In a world dominated by a single macro factor—currency debasement—spreading capital across underperforming assets guarantees a loss of real value. A concentrated portfolio is now the only logical strategy.
  3. Tech Is Winning, But Crypto Is Lapping It. While the NASDAQ beats debasement, it's losing badly to crypto. The NASDAQ is down over 99% against Bitcoin since 2012, making crypto the apex asset for accumulating real wealth.
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July 9, 2025

Crypto Experts Explain Stablecoins & the Future Financial System w/ Ali Yahya & Arianna Simpson

a16z

Crypto
Key Takeaways:
  1. Stablecoins are the Trojan Horse. They are crypto's killer app, driving real-world utility and legitimizing the space for institutions and mainstream users by solving tangible financial inefficiencies.
  2. Crypto is AI’s Essential Counterbalance. As AI centralizes power and blurs reality, crypto provides the critical infrastructure for decentralization, authentication, and new economic models for creators.
  3. The Regulatory Winter is Over. A friendlier U.S. political climate has opened the door for a new wave of crypto innovation. For investors and builders, this is the signal that it's time to build.
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