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AI Podcasts

December 13, 2025

Minimax M2 – Olive Song, MiniMax

AI Engineer

AI
Key Takeaways:
  1. **The "Small is Mighty" Paradigm:** Don't underestimate smaller, specialized models. M2 proves that smart engineering, real-world feedback, and iterative reasoning can outperform larger models in specific, high-value domains.
  2. **Builders, Embrace Iteration:** Design your agents with "interleaved thinking." The ability to self-correct and adapt to noisy environments is critical for real-world utility.
  3. **The "So What?":** The next wave of AI agents will be defined by their robustness, cost-effectiveness, and ability to generalize across dynamic environments. M2 is a blueprint for building practical, scalable AI that developers will actually integrate into their daily workflows.
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December 11, 2025

No Priors Ep. 143 | With ElevenLabs Co-Founder Mati Staniszewski

No Priors: AI, Machine Learning, Tech, & Startups

AI
Key Takeaways:
  1. Strategic Shift: The future of human-computer interaction is voice-first, moving from static content to dynamic, personalized, and agentic experiences.
  2. Builder/Investor Note: Defensibility in AI is increasingly found in deep product layers, specialized architectural breakthroughs (especially in audio), and robust ecosystems, not just raw model scale.
  3. The "So What?": Over the next 6-12 months, expect to see significant advancements in proactive AI agents, immersive media, and personalized education, with voice as the core interface.
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December 10, 2025

The Unicorn Founder Who Delegated Everything.

a16z

AI
Key Takeaways:
  1. The AI-Delegation Revolution is Here: Start experimenting with AI tools like ChatGPT for delegation now. The future involves proactive machine assistants deeply integrated into your workflow.
  2. Builders & Investors: Focus on "How to Delegate": The biggest constraint isn't finding assistants, but teaching clients how to delegate effectively. Tools and services that educate delegators will win.
  3. Reclaim Your Ambition: By offloading the mundane, you free up mental bandwidth to think bigger, pursue more ambitious goals, and ultimately, control your most valuable asset: time.
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December 12, 2025

AI Eats the World: Benedict Evans on the Next Platform Shift

a16z

AI
Key Takeaways:
  1. Strategic Implication: The AI bubble is inevitable. Focus on defensible positions: deep product integration, proprietary data, and distribution, rather than just raw model performance.
  2. Builder/Investor Note: The opportunity lies in productizing AI for specific "jobs to be done" within niche industries, creating intuitive UIs, and building in validation, not just building another foundational model.
  3. The "So What?": We're about to figure out the true "job to be done" for many industries. AI will unbundle existing businesses by exposing their hidden inefficiencies or non-obvious defensibilities.
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December 13, 2025

The Mathematical Foundations of Intelligence [Professor Yi Ma]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Embrace Parsimony and Self-Consistency: Adopt these principles as guiding forces in AI design. Build models that not only compress data efficiently but also maintain a high degree of self-consistency to ensure accurate and reliable world models.
  2. Focus on Abstraction, Not Just Memorization: Prioritize developing systems that can abstract knowledge beyond mere memorization. Move beyond surface-level compression and aim for models that can discover and reason about the underlying principles of the world.
  3. Understand and Reproduce the Brain’s Mechanisms: Focus on understanding and reproducing the mechanisms in the human brain that enable deductive reasoning, logical thinking, and the creation of new scientific theories to truly push AI to the next level.
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December 10, 2025

Nav Kumar: Trishool, AI Alignment, Subnet 23, Mechanistic Interpretability, Rogue LLMs | Ep. 75

Ventura Labs

AI
Key Takeaways:
  1. **Prioritize AI Safety Research:** Invest aggressively in understanding and mitigating AI risks to safeguard humanity against potential rogue LLMs.
  2. **Support Decentralized AI Alignment:** Champion decentralized platforms like Bit Tensor and initiatives like Trishool that promote open and transparent AI alignment research.
  3. **Embrace Mechanistic Interpretability:** Drive the development of tools that enable us to understand and control the internal workings of AI models, ensuring alignment with human values.
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December 10, 2025

Everyone Needs an Assistant. Here’s Why.

a16z

AI
Key Takeaways:
  1. Embrace Delegation as a Foundational Skill: Whether you leverage AI or human support, mastering delegation is paramount for unlocking personal and professional potential.
  2. Prioritize Time Ownership: Recognize time as your most valuable asset and design your life and calendar around your highest goals.
  3. Start Small, Scale Intentionally: Begin with affordable AI tools and gradually incorporate human assistance as your budget and needs evolve, building trust and compounding leverage over time.
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December 8, 2025

Building The Chip That Could Unlock AGI | Naveen Rao

a16z

AI
Key Takeaways:
  1. **Embrace Analog:** Explore and invest in analog computing solutions to overcome the energy limitations of current digital AI systems.
  2. **Prioritize Causality:** Shift focus towards AI models that incorporate time and causality, potentially unlocking more advanced and human-like intelligence.
  3. **Support Hardware Innovation:** Invest in and foster startups like Unconventional AI that are tackling fundamental challenges in AI hardware.
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December 8, 2025

Why AI Will Have To Run On Blockchains

The DCo Podcast

AI
Key Takeaways:
  1. Blockchain is essential for AI to ensure censorship resistance and uninterrupted accessibility.
  2. Trustworthy AI agents require on-chain governance to manage assets securely and transparently.
  3. AI agents can drastically accelerate blockchain adoption and optimize corporate processes.
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Crypto Podcasts

August 27, 2025

How to Make it This Cycle w/ CryptoMessi

Taiki Maeda

Crypto
Key Takeaways:
  1. Ditch the Rotator Playbook. This isn't 2021. Stop chasing every pump. Success this cycle requires picking a few narratives, believing in them, and holding with conviction.
  2. Make On-Chain Money Real. Stablecoins encourage bad habits. Cash out profits to a real bank account to create a psychological barrier against recklessly aping your gains back into the market.
  3. Plan for Post-Win Depression. The dopamine crash after a massive score is inevitable. Resist the urge to chase that high; prioritize building sustainable, real-world income instead of buying status symbols.
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August 27, 2025

Trump’s Tariffs Could Stall Growth Before 2026 Surge | Alfonso Peccatiello

Forward Guidance

Crypto
Key Takeaways:
  1. A Politicized Fed is the Baseline. Assume the Federal Reserve will be pressured to cut rates to neutral (~3%) by 2026, creating an unusually loose policy backdrop relative to strong nominal growth.
  2. Mind the Fiscal Cliff, Then the Rocket Ship. Brace for a temporary growth slowdown as tariffs bite over the next few months, but prepare for a sharp re-acceleration in 2026 if and when new stimulus kicks in.
  3. Ditch Old Hedges, Buy Protest Assets. Your portfolio's traditional diversifiers (long bonds, USD) are broken. Shift allocation toward assets that benefit from inflation risk and high nominal growth: commodities, crypto, and undervalued international equities.
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August 26, 2025

Ep 46 — How to Turn a Dying NFT Collection into a $50M Cultural Empire in Web3 ft. Luca Netz

The DCo Podcast

Crypto
Key Takeaways:
  1. **Valuation is Evolving.** The most durable crypto projects will be judged not on tokenomics alone, but on a triad of community strength (Ecosystem), marketing reach (Attention), and real-world cash flow (Revenue).
  2. **Centralization Wins the Consumer.** The next billion users will not navigate a dozen dApps. They will be onboarded through simplified, centralized super-apps that provide a seamless and curated on-chain experience.
  3. **Reward Loyalty, Not Speculation.** Sustainable value is built by aligning with true believers. Founders should design mechanisms that reward long-term holders and actively discourage "farm-and-dump" behavior.
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August 26, 2025

Why I Sold Some Crypto & Prediction Markets Alpha

Taiki Maeda

Crypto
Key Takeaways:
  1. Re-evaluate Risk/Reward. With majors like Ethereum potentially offering symmetrical 50% upside vs. 50% downside, the rationale for holding heavy, levered positions weakens. It's time to take some chips off the table.
  2. Explore Prediction Markets. This sector offers a fresh frontier for alpha. Get active on Polymarket, farm the Limitless airdrop on Base (min. $200 bet), and join Outcome’s risk-free testnet competition to get exposure.
  3. Build a Defensive Core. Adopt assets like JLP on Solana as a portfolio cornerstone. It provides market exposure while protecting capital through its diversified pool and fees generated from retail traders, outperforming most crypto assets in a downturn.
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August 26, 2025

Will Crypto Peak in 2025… or Run Into 2026? Onchain Data Signals

Bankless

Crypto
Key Takeaways:
  1. **This Time Might Be Different.** Macro indicators like loosening bank lending standards, mid-range equity valuations, and a dovish Fed signal the business cycle is earlier than many believe, favoring a cycle extension into 2026 over a 2025 peak.
  2. **On-Chain Metrics Show No Signs of a Top.** Key on-chain data is far from euphoric. The Bitcoin Fear & Greed index is neutral, and while long-term holders are selling, it’s being absorbed without triggering the "extreme greed" that defines market tops.
  3. **Build a Concentrated, High-Conviction Portfolio.** Don't "diworsify." Anchor 70%+ of your portfolio in core assets (BTC, ETH), benchmark all other bets against them, and use small "hot sauce" allocations (5-10%) for high-risk plays while always maintaining cash to buy the dips.
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August 25, 2025

Can Rate Cuts Save Crypto’s Bull Market?

1000x Podcast

Crypto
Key Takeaways:
  1. **Macro is your north star.** The crypto market's direction is dictated by Fed policy. Rate cuts are the narrative, and trillions are waiting on the sidelines to flood into risk assets.
  2. **Take profits aggressively.** We are in the "stupid" phase of the cycle. Systematically sell portions of your holdings at 20%, 50%, and 100% gains to de-risk before the music stops.
  3. **Scrutinize DAOs.** Many are exit liquidity schemes. Only consider those with strong guardrails, like mandatory fresh capital matching, that bring new money into the ecosystem.
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