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AI Podcasts

March 19, 2025

Can AI Fix DeFi? The Rise of "DeFAI" and Crypto AI Agents

The People's AI

AI

Key Takeaways:

  • 1. AI has the potential to unlock the true promise of DeFi by simplifying user experience and broadening access.
  • 2. The rise of AI agents may fundamentally reshape the DeFi ecosystem, with protocols adapting to automated interactions.
  • 3.  Balancing automation with security and user control is crucial for the responsible development of AI-powered DeFi.
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March 20, 2025

Hash Rate - Ep 101 - Bittensor Fund I: Investing in Subnets

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI

Key Takeaways:

  • 1. The Bittensor subnet ecosystem offers potentially asymmetric investment opportunities, similar to early Ethereum or DeFi Summer.
  • 2. Simplified user interfaces and cross-chain bridges are crucial for attracting mainstream capital.
  • 3. The convergence of new capital, increasing subnet adoption, and the rise of decentralized AI position Bittensor for potentially explosive growth.
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March 19, 2025

Illia Polosukhin on The Upcoming Explosion of User-Owned AI

The Rollup

AI

Key Takeaways:

  • 1. User-owned AI offers a powerful alternative to centralized models, prioritizing user control, data privacy, and personalized experiences.
  • 2. Near Protocol is building the necessary infrastructure and protocols to support the development, deployment, and monetization of user-owned AI agents.
  • 3. The future of AI and crypto will see the rise of useful agents that can perform real-world tasks, creating new opportunities for developers and users alike.
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March 19, 2025

npm install Agents — with Sunil Pai and Rita Kozlov (VP AI) of Cloudflare

Latent Space

AI

Key Takeaways:

  • 1. Cloudflare is leveraging its existing Durable Objects technology to create a compelling platform for developing and deploying AI agents.
  • 2. The future of AI agents hinges on solving challenges related to trust, practical applications, and accessibility for non-technical users.
  • 3. Cloudflare Agents is poised to address these challenges by offering a robust, scalable platform with features like human-in-the-loop, scheduling, and future support for multi-agent communication and enhanced workflows.
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March 18, 2025

The Gap Between Humans and Machines Is ___

Machine Learning Street Talk

AI

Key Takeaways:

  • 1. Robustness, not just accuracy, is crucial for LLMs to gain trust and widespread adoption.
  • 2. Human feedback should be used strategically and granularly to mitigate biases and optimize model behavior effectively.
  • 3. Dynamic, evolving benchmarks tailored to specific tasks are necessary to truly evaluate the evolving capabilities of increasingly sophisticated AI systems.
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March 15, 2025

Building the Next Generation of Conversational AI

a16z

AI

Key Takeaways:

  • 1. AI development requires balancing technical rigor with qualitative user feedback to create truly engaging experiences.
  • 2. The future of conversational AI lies in eliminating transcription, allowing direct audio processing for faster, more natural interactions.
  • 3. AI companions are poised to become a new computing interface, emphasizing natural, human-like interactions over traditional utility.
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March 14, 2025

Snipd: The AI Podcast App for Learning — with CEO Kevin Ben-Smith

Latent Space

AI

Key Takeaways:

  • 1. Snipd is transforming podcast consumption by focusing on knowledge retention and learning through AI-enhanced features.
  • 2. The app's evolution reflects a shift from social sharing to a more personalized, learning-centric experience.
  • 3. Future developments include voice interfaces and AI-driven discovery, promising a more interactive and tailored user experience.
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March 13, 2025

[Lightning Pod] Evals: How to Improve AI Consistently — with Hamel Husain and Shreya Shankar

Latent Space

AI

Key Takeaways:

  • 1. Evals are essential for moving AI applications from demo to production, requiring systematic measurement and data literacy.
  • 2. Teaching evals involves hands-on, practical approaches to ensure understanding and application of stable, evergreen techniques.
  • 3. Custom data annotation tools and careful validation of LLMs as judges are crucial for effective evals.
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March 13, 2025

Vibecoding is Here - How AI is Changing How We Build Online

a16z

AI

Key Takeaways:

  • 1. Vibecoding democratizes software development, enabling a broader range of users to create applications without traditional coding skills.
  • 2. The rapid growth of AI-powered tools highlights a significant demand for accessible software development solutions.
  • 3. Despite challenges, the potential for Vibecoding to transform how we build software is immense, with ongoing improvements expected to address current limitations.
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Crypto Podcasts

July 9, 2025

The Only Assets That Beat Fiat Debasement | Raoul Pal & Julien Bittel

Forward Guidance

Crypto
Key Takeaways:
  1. Concentrate, Don't Diversify: In a world driven by a single macro factor (debasement), diversification is a losing strategy. The only assets generating real purchasing power are technology stocks and crypto.
  2. The Business Cycle Is Broken, Not Dead: The old rules of cyclical recessions are on hold. Central banks will print money to prevent any systemic credit event, meaning any dip or crisis is met with more liquidity, further fueling the outperforming assets.
  3. The "Banana Zone" Is Coming: The current market setup, with easing financial conditions and rising global M2, mirrors past explosive cycles like 2017. The stage is set for a significant rally in risk assets, particularly crypto and tech, extending into 2025.
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July 8, 2025

Ethereum's Strategy to Win Over Wall Street

Bankless

Crypto
Key Takeaways:
  1. **The SEC's Attack Backfired.** The agency’s attempt to decapitate Ethereum was thwarted by the very decentralization it failed to understand, forcing the ecosystem to legally fortify its position and prove its resilience under extreme pressure.
  2. **Wall Street Wants Credible Neutrality.** Forget the narrative that institutions fear decentralization. They are actively seeking it as the ultimate hedge against counterparty risk, making Ethereum’s core values its most valuable asset in the next wave of adoption.
  3. **The Accumulation Race Is On.** A new institutional playbook is emerging. Corporate treasuries, like Sharplink Gaming’s ETH vehicle, are not just buying and holding ETH. They are aggressively accumulating it and deploying it in staking and DeFi to grow their exposure, signaling a massive race to acquire "high-powered money" in an era of currency debasement.
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July 7, 2025

Is Crypto Still The Best Trade?

1000x Podcast

Crypto
Key Takeaways:
  1. The Altcoin Graveyard Is Bitcoin's Tailwind. Capital is fleeing "useless" tokens and the defunct VC model, creating steady inflows for Bitcoin. The primary trade is now long BTC, short everything else.
  2. From HODL to Tactical Alpha. The days of 100x returns on random tokens are gone. Generating alpha now requires sophisticated strategies like pairs trading, selling options volatility against spot holdings, and capitalizing on short-term macro events.
  3. S&P is the New Dollar, Bitcoin is the New S&P. As the dollar loses its luster, the S&P 500 has become the default savings vehicle. Bitcoin has cemented its role as the premier risk-on asset within that new paradigm—a bet that “probably won’t” fail.
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July 7, 2025

Permissionless: The Next Generation of Consumer Crypto Apps

0xResearch

Crypto
Key Takeaways:
  1. Wallets are Dead, Long Live Wallets: The future isn't a separate wallet app. It's an embedded, invisible experience inside the consumer apps themselves, just like friend.tech demonstrated.
  2. From Gatekeepers to Curators: Centralized exchanges are becoming obsolete as gatekeepers. The new frontier is building sophisticated curation engines to help users discover signal in a sea of noise.
  3. AI Agents are the Next Big User Base: The most forward-thinking founders aren't just building for humans; they're building for a future where AI agents drive the majority of on-chain trading volume.
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July 5, 2025

How To Improve Solana's Market Structure | Eugene Chen

Lightspeed

Crypto
Key Takeaways:
  1. **Stop Chasing Max Decentralization.** The market has voted with its volume. Users prioritize performance over ideological purity. "Verifiable Finance"—with centralized sequencers but guaranteed withdrawals—is the pragmatic path forward.
  2. **Market Structure Is Destiny.** Inefficient L1s with toxic MEV force sophisticated teams to build workarounds (like the proprietary AMM Sulfi) or entirely new, controlled environments (like Atlas). The base layer's design dictates the quality of applications built on top.
  3. **The Real Game Is Efficient Markets, Not Memecoins.** The long-term vision for crypto finance depends on building infrastructure that can attract institutional capital with fair, reliable, and highly efficient execution. The current system that incentivizes "bad fills" is a dead end.
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July 4, 2025

0xResearch Cross-Post: Crypto Regulation, Breakout Apps, and TradFi’s Impact | Jon Charbonneau

Bell Curve

Crypto
Key Takeaways:
  1. Go-to-Market > Tech Specs: In the race between new chains, attracting a single breakout app is more critical than marginal performance gains. Value accrues to whoever owns the user relationship.
  2. Bet on Improvable Niches: The biggest startup opportunities are in high-demand but clunky sectors like prediction markets and memecoin launchpads, where superior UX can create a dominant new player.
  3. Look Forward, Not Sideways: Don't get trapped by the "revenue meta." Successful investing requires a forward-looking view of a project’s potential to capture future value, a lesson exemplified by the early thesis for Solana.
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