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AI Podcasts

December 31, 2025

[State of Research Funding] Beyond NSF, Slingshots, Open Frontiers — Andy Konwinski, Laude Institute

Latent Space

AI
Key Takeaways:
  1. The transition from monolithic models to compound systems means the value is migrating to the orchestration and context layer.
  2. Prioritize tools like DSPy and context management frameworks to build high-leverage applications that do not depend on proprietary model updates.
  3. Open research is the only way to maintain a competitive edge. If the US stops publishing, it stops leading.
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December 31, 2025

Infinity, Paradoxes, Gödel Incompleteness & the Mathematical Multiverse | Lex Fridman Podcast #488

Lex Fridman

AI
Key Takeaways:
  1. From Singular Logic to Pluralistic Systems. As we build complex AI, we must move from seeking one "correct" model to managing a multiverse of conflicting but internally consistent logical frameworks.
  2. Audit for Incompleteness. When designing protocols, identify the "independent" variables that your system cannot prove or settle internally.
  3. Truth is bigger than code. Over the next year, the winners will be those who stop trying to "solve" the universe and start navigating the multiverse of possible truths.
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December 31, 2025

AI in 2026: 3 Predictions For What’s To Come (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. Outcome-Based Intelligence. We are moving from AI as a Service to AI as an Outcome where value is tied to results rather than usage.
  2. Target Non-Public Data. Build applications in sectors like law or lending where the most valuable data is private and un-crawlable.
  3. The next two years will separate companies that use AI to save pennies from those that use AI to capture entire markets through autonomous systems and proprietary data loops.
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December 30, 2025

Your Brain Doesn't Command Your Body. It Predicts It. [Max Bennett]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The macro pivot: The transition from static data training to interactive world models that perform active inference.
  2. The tactical edge: Prioritize AI architectures that incorporate continual learning and hypothesis testing rather than just scaling parameters.
  3. The next decade belongs to those who replicate the biological transition from observation to interactive simulation.
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December 31, 2025

The Algorithm That IS The Scientific Method [Dr. Jeff Beck]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The Macro Transition: Move from Big Data mimicry to Small Data causal reasoning.
  2. The Tactical Edge: Prioritize Active Inference frameworks that track uncertainty.
  3. AGI won't come from bigger LLMs; it will come from agents that possess a physics-grounded world model.
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December 30, 2025

[State of AI Startups] Memory/Learning, RL Envs & DBT-Fivetran — Sarah Catanzaro, Amplify

Latent Space

AI
Key Takeaways:
  1. The transition from stateless chat interfaces to stateful, personalized agents that learn from every interaction.
  2. Prioritize memory. If you are building an application, treat state management and continual learning as your core technical moat to prevent user churn.
  3. Stop chasing clones of existing apps for reinforcement learning. Use real-world logs and traces to build models that solve actual engineering friction.
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December 30, 2025

[State of RL/Reasoning] IMO/IOI Gold, OpenAI o3/GPT-5, and Cursor Composer — Ashvin Nair, Cursor

Latent Space

AI
Key Takeaways:
  1. The transition from internet-scale imitation to environment-scale RL.
  2. Build products that capture the full context of a professional's workflow to make them RL-ready.
  3. Intelligence is no longer the bottleneck. The winner will be whoever builds the best hard drive for professional context.
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December 31, 2025

[State of Post-Training] From GPT-4.1 to 5.1: RLVR, Agent & Token Efficiency — Josh McGrath, OpenAI

Latent Space

AI
Key Takeaways:
  1. The Macro Pivot: Intelligence is moving from a scarce resource to a commodity where the primary differentiator is the cost per task rather than raw model size.
  2. The Tactical Edge: Prioritize building on models that demonstrate high token efficiency to ensure your agentic workflows remain profitable as complexity grows.
  3. The Bottom Line: The next year will be defined by the systems vs. models tension. Success belongs to those who can engineer the environment as effectively as the algorithm.
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December 31, 2025

[State of Evals] LMArena's $100M Vision — Anastasios Angelopoulos, LMArena

Latent Space

AI
Key Takeaways:
  1. The transition from static benchmarks to "Vibe-as-a-Service" means model labs must optimize for human delight rather than just loss curves.
  2. Use Arena’s open-source data releases to fine-tune models on real-world prompt distributions.
  3. In a world of synthetic data and benchmark saturation, human preference is the only remaining scarce resource for validating frontier capabilities.
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Crypto Podcasts

October 24, 2025

Live Weekly Roundup With Kevin Ricoy

Lightspeed

Crypto
Key Takeaways:
  1. Sell the News, Buy the Self-Own. Eclipse’s price action demonstrates that in crypto, counter-narrative marketing can be more effective than traditional hype. When a project publicly acknowledges its own failures, it can signal a market bottom.
  2. Culture is Strategy. The contrast between Ethereum’s perceived complacency and Solana’s hungry underdog ethos directly impacts developer incentives and innovation speed. Ecosystems with a clear, aggressive mission attract and retain talent differently.
  3. Watch the SKR Token. As only the second token from Solana Labs, the SKR launch carries significant reputational weight. Investors should monitor its mechanics, as it will likely set a new standard for ecosystem projects launched by a parent company.
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October 22, 2025

Is the Cycle Over, Portfolio Psychology, & Prediction Market Alpha

1000x Podcast

Crypto
Key Takeaways:
  1. Fade the Cycle Narrative: The influx of new, cycle-agnostic capital via ETFs means the market's rhythm has changed. Sideways price action is the new up, signaling strong demand is absorbing OG selling.
  2. Buy Picks, Shovels, and Yield: The era of riding hyped, valueless memecoins is over. The durable strategy is to own the infrastructure (Robin Hood) or assets that generate and return real fees to holders (Shuffle, Aerodrome).
  3. Arbitrage Information Gaps: Find your edge in niche markets. Exploitable alpha exists in prediction markets, whether through contrarian betting, language advantages, or AI-powered analysis.
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October 22, 2025

State Of Crypto 2025 | a16z Crypto — Eddy Lazzarin & Daren Matsuoka

Bankless

Crypto
Key Takeaways:
  1. Stablecoins Are The Trojan Horse. They have achieved undeniable product-market fit, rivaling legacy payment rails and becoming a key tool for U.S. dollar dominance. They are the gateway for both institutional players and everyday users in emerging markets.
  2. Usage is Divorced From Speculation. For the first time, practical on-chain activity is being driven by users in developing nations who *need* crypto, while speculation is led by those in developed nations who *want* it. The next bull run will be driven by products that bridge this divide.
  3. The Bottleneck is No Longer Technology. With scalability largely solved (blockchains now process over 3,400 TPS), the primary barriers to adoption have shifted from infrastructure to product design, user experience, and regulatory clarity.
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October 22, 2025

MegaETH Co-Founder: How We Rebuilt Ethereum From the Ground Up

The DCo Podcast

Crypto
Key Takeaways:
  1. Question Sacred Cows: The path to breakthrough performance lies in challenging foundational assumptions. For Layer 2s, this means recognizing that sequencer decentralization may be a solution in search of a problem.
  2. Focus and Outsource: MegaETH’s strategy is simple: be the best at performance by outsourcing the hardest part—consensus—to Ethereum. This allows them to build a hyper-optimized execution environment without compromising on security.
  3. Hire Outside the Echo Chamber: The next major blockchain innovation may not come from a crypto veteran. Expertise from adjacent fields like low-latency computing can provide the first-principles thinking needed to solve the industry’s most entrenched problems.
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October 22, 2025

Institutional Demand for Crypto is Accelerating | Matt Hougan

Forward Guidance

Crypto
Key Takeaways:
  1. **Allocations Are Multiplying:** The standard institutional crypto allocation is moving from a timid 1% to a more confident 3-5%, driven by crypto's declining volatility and the fading fear of a "go-to-zero" event.
  2. **The ETF Universe is Exploding:** New SEC guidelines will unleash a wave of crypto ETFs, from single assets to index funds. This will reshape market structure and provide traditional investors with simple on-ramps to the entire ecosystem.
  3. **Stablecoins are the Real Trojan Horse:** Beyond Bitcoin, institutional demand for stablecoins is immense. They aren't just an asset; they are recognized as the critical settlement layer for a tokenized, 24/7 global market.
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October 21, 2025

Inside Coinbase’s $375m Acquisition of Echo | Shan Aggarwal

Empire

Crypto
Key Takeaways:
  1. Becoming the Capital Stack: Coinbase's endgame is not just being a crypto exchange but providing the full, end-to-end infrastructure for any company—crypto or traditional—to issue, manage, and raise capital on-chain.
  2. Acquire Missionaries, Not Mercenaries: Their M&A success hinges on a proactive, culture-first approach. They identify strategic needs, hunt for the best teams, and integrate them deeply, ensuring founders stay long after their earnouts expire.
  3. Prediction Markets are the Next Trojan Horse: Coinbase is betting big on prediction markets to onboard the next wave of mainstream users, using familiar activities like sports betting as an accessible entry point into the crypto ecosystem.
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