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AI Podcasts

December 16, 2025

Nvidia's Generative AI ecosystem supporting Japan's sovereign AI

Weights & Biases

AI
Key Takeaways:
  1. Ecosystem Dominance: NVIDIA's strategy extends beyond hardware; they are building an end-to-end ecosystem of software, open-source models, and direct support, making them indispensable for national AI initiatives.
  2. Builder Opportunity: Leverage NVIDIA's open-source Blueprints for agentic AI and Nemotron models for high-performance, customizable solutions. Prioritize local context in model training and data.
  3. Strategic Imperative: Sovereign AI is a growing global trend. Nations and companies that can build and control AI tailored to their specific cultural, linguistic, and regulatory environments will gain a significant advantage in the coming years.
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December 16, 2025

Build reliable AI agents using W&B Training

Weights & Biases

AI
Key Takeaways:
  1. The democratization of RL fine-tuning will accelerate the development and deployment of more reliable and sophisticated AI agents across industries.
  2. Builders should explore open-source LLMs combined with RL fine-tuning as a cost-effective strategy to achieve specific performance benchmarks, especially where latency and cost are critical.
  3. Platforms abstracting infrastructure complexity and providing integrated tooling for the entire AI development lifecycle are crucial for the next phase of AI agent deployment.
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December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Pre-Training is the New Frontier: The next leap in AI capabilities, particularly for agentic systems, will come from fundamental advancements in pre-training, not just post-training tweaks.
  2. Builders & Investors: Focus on teams rethinking loss objectives, curating high-quality reasoning data, and developing dynamic benchmarks for agentic capabilities. Be wary of "agentic" claims that lack foundational pre-training innovation.
  3. The "So What?": Over the next 6-12 months, expect a push for new benchmarks and data strategies that explicitly train models for multi-step planning, long-form reasoning, and error recovery, moving beyond simple next-token prediction.
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December 16, 2025

What We Learned Deploying AI within Bloomberg’s Engineering Organization – Lei Zhang, Bloomberg

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: AI fundamentally changes the economics of software development. Organizations must re-evaluate what constitutes "high-quality" engineering and adapt their processes.
  2. Builder/Investor Note: Prioritize platforms that provide guardrails and guidance for AI tool usage, focusing on deterministic verification and robust testing. Uncontrolled AI deployment risks technical debt.
  3. The "So What?": The next 6-12 months will see a bifurcation: companies that strategically integrate AI into their engineering culture and platforms will gain significant efficiency, while those that don't will struggle with quality and adoption.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Workflow Automation is the New Frontier: The real value of AI in developer tools comes from orchestrating entire workflows, not just individual point solutions.
  2. Embed for Adoption: Tools must integrate seamlessly into existing workflows and IDEs (like Cursor) to achieve high usage.
  3. Support as a Code-Shipping Powerhouse: Empowering non-traditional roles with AI-driven code generation leverages their unique, real-time context, creating significant operational leverage.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Semantic Shift: The future of AI in code moves from text generation to deep semantic understanding and execution simulation.
  2. Builder Opportunity: Develop next-generation debugging tools and code agents that leverage internal simulation for faster, more efficient development cycles.
  3. Investor Focus: Prioritize models and platforms that demonstrate explicit execution modeling, as this capability will redefine software development and create new market leaders.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Infrastructure Shift: AI-driven kernel optimization addresses a critical bottleneck in scaling AI compute, enabling more efficient use of diverse hardware.
  2. Builder/Investor Note: Focus on solutions with robust, hardware-verified performance metrics and a clear human-in-the-loop strategy. AI is a powerful tool for automating optimization, not a magic bullet for novel algorithmic breakthroughs.
  3. The "So What?": This technology frees expert engineers from tedious optimization, allowing them to focus on higher-level research and truly innovative algorithmic design, accelerating the pace of AI development in the next 6-12 months.
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December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The era of "free money" inflated the number of perceived compounders; a return to positive real rates demands a sharper focus on businesses demonstrating genuine financial discipline and competitive advantage.
  2. Builder/Investor Note: Seek out "Act 2" entrepreneurs and companies that can leverage AI to transform existing physical or IP-based advantages, not just create new AI products. Be prepared to buy more when market sentiment turns negative on strong businesses.
  3. The "So What?": The next 6-12 months will differentiate companies that merely adopt AI from those that strategically integrate it to build durable, uncatchable cost and distribution advantages.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. The Future of Policing is Intelligent: Integrating AI, drones, and smart cameras creates a precise, accountable, and safer policing model for both officers and communities.
  2. Invest in the "How": Builders and investors should focus on technologies that enhance certainty of capture, streamline judicial processes, and support public-private partnerships to modernize urban safety infrastructure.
  3. Safety Fuels Mobility: Eliminating crime is not just about law enforcement; it's about restoring the fundamental safety required for economic mobility and a functional society.
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Crypto Podcasts

July 24, 2025

Why I Ditched Bitcoin Mining for Ethereum

Bankless

Crypto
Key Takeaways:
  1. **The Bitcoin Mining Business is Broken.** The model of guaranteed profit-halving and a relentless hardware arms race is unsustainable, forcing miners to pivot to more viable ventures like AI infrastructure or ETH staking.
  2. **Ethereum's Target is 10x Bigger Than Bitcoin's.** Ethereum isn't competing with Bitcoin; it's competing with the multi-trillion-dollar traditional finance industry. Its utility in powering stablecoins and DeFi makes its total addressable market exponentially larger.
  3. **A New "Race to a Billion" in ETH Has Begun.** The new competitive arena for public crypto companies is the ETH treasury. Success hinges on aggressive acquisition, capturing investor mindshare, and—critically—generating superior, risk-adjusted yield through staking.
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July 23, 2025

Exposing Crypto Market Makers With Matt Jobbé-Duval

Lightspeed

Crypto
Key Takeaways:
  1. **The Playbook is a Trap.** So-called "active market making" is a destructive financing loop. Projects trade their future for a brief, artificial price pump fueled by selling locked tokens at catastrophic discounts.
  2. **Perps Are the Canary in the Coal Mine.** A sudden, plummeting perpetual futures funding rate is a massive red flag. It often signals that insiders are rushing to hedge their positions before an imminent and devastating spot price collapse.
  3. **Your Chart Is Your Reputation.** Once a token's chart is destroyed by one of these schemes, it becomes incredibly difficult to be taken seriously by the community, investors, or builders, leaving a permanent stain on the project's credibility.
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July 22, 2025

Trading Bitcoin Cycles With Willy Woo

1000x Podcast

Crypto
Key Takeaways:
  1. Don't Get Sidelined. Most of the cycle's gains happen in a handful of days. Trying to trade in and out of a bull market is a high-risk strategy that can easily leave you behind.
  2. Watch the Macro Clock. The Bitcoin cycle top will be dictated by the timing of the global business downturn. This, not internal metrics, is the primary indicator to watch.
  3. Use Price Levels as Triggers, Not Targets. If the macro downturn hits this year, a cycle top in the $140k-$160k range is plausible. Use these levels to re-evaluate risk rather than trying to perfectly time an unknowable peak.
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July 23, 2025

CRYPTOCURRENCY TALK: TALOS, PUMP, ETHENA, HYPERLIQUID - 0xResearch and Friends

0xResearch

Crypto
Key Takeaways:
  1. Product Is King. The market consistently rewards applications that prioritize a simple, effective user experience. Hyperliquid’s mobile integration and the rise of intents-based bridging show that abstract infrastructure plays are losing ground to products that just work.
  2. Incentives Need a Narrative. Pump.fun’s gigantic treasury is a powerful tool, but without a clear strategy and strong communication from the team, it's not enough to prevent a massive loss of market share and investor confidence.
  3. De-Risking Is the New Black. Mature protocols like Ethena are actively moving to reduce complexity and risk, even at the cost of marginal yield. This signals a broader shift towards sustainability and resilience over chasing every last basis point.
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July 22, 2025

Empire Cross-Post: DC Crypto Week Takeaways With Rebecca Rettig & Alexander Grieve

Bell Curve

Crypto
Key Takeaways:
  1. Stablecoins are Mainstream Infrastructure. The Genius Act solidifies stablecoins as a key pillar of the future financial system. For founders and investors, the largest immediate opportunities are in building white-label issuance platforms and other ancillary services for traditional companies.
  2. ICOs Are Back, But With Guardrails. The Clarity Act paves the way for a resurgence in token pre-sales by creating a compliant fundraising path. Founders gain a new capital formation tool, while investors get a clearer framework, albeit with longer lockups for insiders.
  3. The Next Battle is Taxes. With stablecoin and market structure frameworks advancing, the next major regulatory hurdle is tax. Expect a significant push to clarify the tax treatment of staking rewards and other on-chain activities, which will be critical for integration into products like ETFs.
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July 22, 2025

The Truth Behind Crypto Market Makers | Matt Jobbé-Duval

Lightspeed

Crypto
Key Takeaways:
  1. The Call Option's Double Edge: The standard call-option deal is an elegant solution to crypto's volatility, but it becomes toxic when the loan is too large. An oversized option creates a "magnet effect" where the price gets pinned to the strike, killing healthy price discovery.
  2. "Active Market Making" Is a Trap: Selling the future to pump the present is a fool's game. This structure leverages a project’s future token supply for a short-term price pump that almost always ends in a perp-driven death spiral, destroying credibility.
  3. Launch Price Is Vanity, Momentum Is Sanity: The initial TGE price is an illusion driven by retail FOMO. Projects should focus on establishing a fair pre-launch price and using stabilization mechanisms to build sustained momentum, rather than chasing a fleeting, sky-high valuation on day one.
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