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AI Podcasts

August 21, 2025

Can AI Fix Housing and Healthcare Affordability?

a16z

AI
Key Takeaways:
  1. AI is the deflationary force for stagnant sectors. While software ate the world, it skipped housing and healthcare. AI is finally tackling the operational drag that has caused costs to balloon for decades.
  2. To solve the housing crisis, make it profitable. The path to more housing supply runs through better returns. By making property operations radically more efficient, AI attracts the capital required to build.
  3. The future of work is human + AI. Automation won't eliminate jobs; it will transform them. As AI handles the administrative grind, human roles will shift to higher-value work like community engagement and complex problem-solving.
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August 19, 2025

Hash Rate - Ep 129 - Macrocosmos IOTA (sn9) and DataUniverse (sn13)

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI
Key Takeaways:
  1. DTO Means Business: Dynamic TAO has forced a Darwinian shift. Subnets must now achieve product-market fit and generate real revenue to survive, transforming from research projects into self-sustaining businesses.
  2. IOTA’s Grand Ambition: IOTA (SN9) isn't just another model trainer; its architecture aims to train trillion-parameter models on decentralized, consumer-grade hardware, directly challenging the dominance of centralized AI labs.
  3. Time to Garden: The protocol's long-term health hinges on active governance. A strong sentiment is emerging to prune low-effort or malicious subnets to focus emissions on projects capable of creating real, lasting value.
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August 19, 2025

Hash Rate - Ep 128 - Ridges ($TAO Subnet 62)

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

AI
Key Takeaways:
  1. AI Is Moving from Copilot to Pilot. Ridges is betting that the future isn't AI assisting humans, but AI replacing them for specific tasks. Their goal is to make hiring a software engineer as simple as subscribing to a service.
  2. Decentralized Economics Are a Moat. By leveraging Bittensor's incentive layer, Ridges outsources a $15M/year R&D budget to a global pool of competing developers, achieving a cost structure and innovation velocity that centralized players cannot match.
  3. The Breakout Subnet Is Coming. Ridges showcases how a Bittensor subnet can solve real-world business problems—privacy, cost, and quality degradation—to build a product that is not just cheaper, but fundamentally better than its centralized counterparts.
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August 18, 2025

Dylan Patel on GPT-5’s Router Moment, GPUs vs TPUs, Monetization

a16z

AI
Key Takeaways:
  1. From Performance to Profit: The AI industry is pivoting from a war of benchmarks to a game of unit economics. Features like GPT-5’s router signal that cost management and monetization are now as important as model capabilities.
  2. Hardware is a Supply Chain Game: Nvidia’s true moat is its end-to-end control of the supply chain. Competitors aren't just fighting a chip architecture; they're fighting a logistical behemoth that consistently out-executes on everything from memory procurement to time-to-market.
  3. The Grid is the Limit: The biggest check on AI’s expansion is the physical world. The speed at which new power infrastructure and data centers can be built will dictate the pace of AI deployment in the US, creating a major advantage for those who can build faster.
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August 18, 2025

Subnet 56 :: Gradients :: Bittensor End-to-end AI Model Training Suite

Opentensor Foundation

AI
Key Takeaways:
  1. Performance is Proven, Not Promised. Gradients isn't just making claims; it’s delivering benchmark-crushing results, consistently outperforming centralized incumbents and producing state-of-the-art models.
  2. Open Source Unlocks the Enterprise. The shift to verifiable, open-source training scripts is a direct solution to customer data privacy concerns, turning a critical vulnerability into a competitive advantage.
  3. The AutoML Flywheel is Spinning. The network's competitive, tournament-style mechanism creates a self-optimizing system that continuously aggregates the best training techniques, ensuring it remains at the cutting edge.
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August 16, 2025

Google DeepMind Lead Researchers on Genie 3 & the Future of World-Building

a16z

AI
Key Takeaways:
  1. **World Models Are a New Modality.** Genie 3 is not just better video; it's an interactive environment generator. This divergence from passive, cinematic models like Veo signals a new frontier focused on agency and simulation, creating a distinct discipline within generative AI.
  2. **Simulation Is the Key to Embodied AI.** The biggest hurdle for robotics is the lack of realistic training environments. Genie 3 tackles this "sim-to-real" gap head-on, providing a scalable way to train agents on infinite experiences before they ever touch physical hardware.
  3. **Emergent Properties Will Drive the Future.** Key features like spatial memory and nuanced physics weren't explicitly coded but emerged from scaling. The next breakthroughs in world models will come from discovering these unexpected capabilities, not just refining existing ones.
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August 15, 2025

Greg Brockman on OpenAI's Road to AGI

Latent Space

AI
Key Takeaways:
  1. AGI is a Compute Game. The primary bottleneck is compute. The process is one of "crystallizing" energy into compute, then into the potential energy of a trained model. More compute means more intelligence.
  2. The Future is a "Manager of Models." AGI won't be a single entity. It will be an orchestrator that delegates tasks to a fleet of specialized models, from fast local agents to powerful cloud reasoners.
  3. Build for Your AI Coworker. To maximize leverage, structure codebases for AI. This means self-contained modules, robust unit tests, and clear documentation—treating the AI as a team member, not just a tool.
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August 15, 2025

Novelty Search August 14, 2025

taostats

AI
Key Takeaways:
  1. Performance is a Solved Problem. For post-training tasks, Gradients has established itself as the best in the world. Developers should stop writing custom training loops and leverage the platform to achieve superior results faster and cheaper.
  2. Open Source Unlocks Trust and Revenue. The pivot to open source directly addresses the biggest enterprise adoption hurdle—data privacy. This move positions Gradients to capture significant market share and drive real revenue to the subnet.
  3. The Bittensor Flywheel is Real. Gradients didn't just beat a major AI lab; its incentive mechanism ensures it will continue to improve at a pace traditional companies cannot match. Miners who don’t innovate are automatically replaced, creating a relentless drive toward optimization.
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August 15, 2025

Subnet 56 :: Gradients :: Bittensor End-to-end AI Model Training Suite

Opentensor Foundation

AI
Key Takeaways:
  1. **Training is a Solved Problem.** For users and developers, the message is clear: stop building custom training loops. Gradients offers superior performance out-of-the-box, turning the complex art of model training into a simple API call.
  2. **Open Source is the Ultimate Competitive Moat.** By making top training scripts public, Gradients accelerates its own innovation flywheel, creating a continuously compounding advantage that closed-source competitors cannot replicate.
  3. **The Best 8B Model is Now from Bittensor.** Gradients has moved beyond theoretical benchmarks to produce a state-of-the-art model that beats a leading industry player. This is a powerful proof-of-concept for the entire Bittensor ecosystem.
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Crypto Podcasts

December 19, 2025

Stablecoins in 2025: The Breakout Year In Review (And What Comes Next...)

The Rollup

Crypto
Key Takeaways:
  1. Strategic Implication: The YBS market is shifting from speculative yield farming to a foundational layer for tokenized finance, driven by institutional interest and RWA integration.
  2. Builder/Investor Note: Prioritize YBS protocols with diversified yield strategies and robust risk management (e.g., first-loss tranches). Builders should focus on RWA infrastructure and sustainable, real-world yield mechanisms.
  3. The "So What?": The convergence of declining traditional rates and maturing RWA tokenization will funnel significant capital into diversified, transparent YBS. Protocols prioritizing these elements will capture the lion's share of the projected $100 billion TVL.
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December 20, 2025

2025 Year In Review Special: AI & Tokenization

The Rollup

Crypto
Key Takeaways:
  1. RWA as a Macro Trend: The tokenization of real-world assets is not a niche but a fundamental shift, attracting significant institutional capital and driving a search for yield beyond traditional instruments.
  2. AI Integration is the Moat: For builders, success in AI hinges on deep integration into existing platforms and workflows, coupled with robust trust and safety mechanisms for autonomous agents.
  3. The Hybrid Future: The market is moving towards centralized frontends (banks, exchanges) offering decentralized, on-chain products. This model bridges user familiarity with crypto-native efficiency, unlocking massive adoption in the next 6-12 months.
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December 20, 2025

How AI Agents Are Replacing Hedge Fund Managers with Pei Chen of Theoriq

The Rollup

Crypto
Key Takeaways:
  1. Agentic Finance is Here: Autonomous AI agents will manage significant capital, requiring robust guardrails and verifiable security.
  2. Distribution Wins: For AI models, deep integration into existing user ecosystems and multi-platform functionality will drive adoption and performance.
  3. Human Roles Evolve: Builders must design for human-AI collaboration, focusing on AI as an accelerator for specialized human expertise, not a full replacement.
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December 19, 2025

Think You Have Token Holder Rights? Think Again - Uneasy Money

Unchained

Crypto
Key Takeaways:
  1. Strategic Implication: The current DeFi landscape is unsustainable without clearer definitions of token holder rights and founder accountability. Expect continued "DAO warfare" and founder exits until these structural issues are addressed.
  2. Builder/Investor Note: For builders, prioritize explicit, transparent legal and technical structures from day one. For investors, assume tokens offer no inherent rights beyond what is explicitly stated and legally enforceable.
  3. The "So What?": The industry needs "light-form" regulatory clarity and standardized norms, potentially driven by centralized exchanges, to foster trust and enable sustainable innovation beyond pure speculation in the next 6-12 months.
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December 19, 2025

Why Crypto as a Subculture Is Dying, but Why That's a Good Thing

Unchained

Crypto
Key Takeaways:
  1. Strategic Implication: The "four-year cycle" driven by speculative behavior is likely dead. The industry's maturation will be marked by sustainable business models, not just macro-driven asset prices.
  2. Builder/Investor Note: Prioritize utility and user experience over tokenomics and crypto-native branding. Invest in projects solving real-world problems for a broad audience, not just those chasing the next airdrop.
  3. The "So What?": The next 6-12 months will see a continued shift towards applications that abstract away blockchain complexity, making crypto an invisible, powerful backend for mainstream products.
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December 20, 2025

Crypto Treasury Stocks Trade Far Below Their Holdings. Is It Time to Buy?

Unchained

Crypto
Key Takeaways:
  1. Strategic Implication: The market is re-evaluating crypto-holding companies, punishing those without clear value-add beyond asset accumulation. The "MNAV of 1" is the expected long-term anchor.
  2. Builder/Investor Note: This is a high-conviction, long-term play, not a quick arbitrage. Investors must conduct deep due diligence on each company's balance sheet, share structure, and operational strategy.
  3. The "So What?": For the next 6-12 months, expect continued volatility and company-specific challenges. The path to MNAV parity will be bumpy, driven by broader market recovery, potential M&A, and individual company execution, not a simple market mechanism.
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