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AI Podcasts

November 17, 2025

Hash Rate - Ep 145 - TAO Subnets Templar (3), Basilica (39), Grail (81)

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. **A New Market is Born:** Templar isn't just cheaper; it enables something that was previously impossible for 99% of the world. Democratizing pre-training means anyone can build a truly custom, sovereign AI.
  2. **Productization is Underway:** Covenant is no longer just a research project. With enterprise sales in motion, the focus is now on revenue. The team has committed that 100% of fees from custom training will be used to buy back its tokens.
  3. **Economics are Being Rewritten:** Basilica’s incentive mechanism is a direct critique of unsustainable models on other compute subnets. Its focus on profitability and positive TAO flow sets a new standard for economic design on Bittensor.
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November 17, 2025

Bryan Johnson: Don’t Die, Beating Entropy, AI Alignment & The Two-Species Future

Bankless

AI
Key Takeaways:
  1. AI Forces a Moral Reboot. The emergence of superintelligence renders our current societal goals dangerously obsolete. Survival must become the new prime directive.
  2. Existence is a Team Sport. The "Don't Die" philosophy is a collective mission ("we don't die") to ensure species-wide survival, not a selfish quest for individual immortality.
  3. Prepare for the Biological Sandbox. Humanity is moving from manipulating physical atoms and digital bits to programming our own biology—a frontier with both unimaginable potential and catastrophic risk.
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November 17, 2025

Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering

a16z

AI
Key Takeaways:
  1. Stop Trying to “Steer” AGI. The control paradigm is a dead end. The goal isn’t a more obedient tool; it’s a trustworthy teammate. We must shift from engineering control to cultivating care.
  2. Alignment is a Process, Not a Product. True alignment isn't a fixed set of rules. It’s a dynamic process of moral learning, akin to raising a child. AIs that only follow rules are brittle and dangerous.
  3. Build for Cooperation, Not Command. The technical path forward involves training AIs in rich, multi-agent environments where they must learn cooperation and theory of mind—the foundational skills for becoming a good member of a group.
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November 16, 2025

Rawson Haverty presents "US & China AI: Lessons from Across the Pacific" | dAGI Summit 2025

Delphi Digital

AI
Key Takeaways:
  1. US Leads in Capital-Intensive Frontier AI; China Excels at Industrial Diffusion. The US leverages deep capital markets for its massive compute buildout and AGI research, while China uses state direction to embed AI into its vast industrial base via open-source models and hardware.
  2. Market Structure Dictates AI Strategy. The US "efficient oligopoly" model prioritizes global dominance and profit reinvestment by a few players. China's "subjugated swarm" model creates intense domestic competition, driving down prices and accelerating adoption at the cost of profitability.
  3. Geopolitical Tension May Be a Necessary Stabilizer. The competition between the US's freedom-oriented, frontier-pushing approach and China's stability-focused, diffusion-driven model creates a complementary tension that could be essential for navigating the "narrow corridor" between AI-driven totalitarianism and uncontrollable chaos.
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November 13, 2025

How Will AI Change Gaming Development? (A Dev’s Take)

The DCo Podcast

AI
Key Takeaways:
  1. Development timelines are collapsing from months to days. AI allows developers to swap entire asset libraries or generate new game concepts at unprecedented speed, turning a two-month art project into a day's work.
  2. The lifespan of any single game is shrinking. Prepare for a world of disposable entertainment. As AI floods the market with content, the strategy will pivot from creating one long-lasting hit to deploying a rapid succession of engaging experiences.
  3. Games are the next evolution of the attention economy. Just as memes became a core tool for community-building around tokens, easily created games will be the next engine for capturing and directing user attention in a hyper-competitive digital world.
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November 11, 2025

AI Nerves, Crypto Realism, Privacy Coins, & Lessons From Trading

1000x Podcast

AI
Key Takeaways:
  1. Adopt a Stock Picker's Mentality. The crypto market is no longer a monolith where a rising tide lifts all boats. Focus on assets with real products, user growth, and cash flow, as the gap between winners and losers will only widen.
  2. Shorting is a Tactical Assault, Not a Siege. Don't "invest" in a short. The only viable short strategies are tactical, targeting specific events like VC unlocks or news-driven spikes. Otherwise, even "total scams" can 5x against you.
  3. Cultivate a Goldfish's Memory. The most critical trading skill is learning how to change your mind. Cut losing trades, forget the loss (but remember the lesson), and redeploy capital without emotional baggage. Stubbornness is a portfolio killer.
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November 11, 2025

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

a16z

AI
Key Takeaways:
  1. Word-of-mouth isn't a feature; it's the engine. Before spending a dime on marketing, obsess over the first 30 seconds of the user experience until people can't help but share it.
  2. Being different is better than being better. Don't build incrementally better slideware. Redefine the core primitives of your category, as Gamma did by moving beyond the 16x9 slide.
  3. Hire painfully slowly to protect your DNA. Resisting the temptation to scale headcount with user growth is a superpower. The goal isn't to hit a hiring target; it's to hire the best people.
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November 7, 2025

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

a16z

AI
Key Takeaways:
  1. AGI Is a Definitional Debate. Progress toward an AI that can replace a remote worker is happening fast. However, achieving "true" human-like learning efficiency may require an entirely new paradigm beyond scaling current LLMs.
  2. The New Creator Economy Is Code. AI is turning software development into a mainstream creative pursuit, empowering a new class of solo entrepreneurs who can build what previously required entire teams.
  3. Incumbents Learned Their Lesson. Unlike past tech shifts, today's giants are aggressively adopting AI, making it both a sustaining *and* disruptive force. The market is large enough for both incumbents and startups to create massive value.
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November 6, 2025

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

a16z

AI
Key Takeaways:
  1. Build the Tools, Not Just the House: CZI’s greatest leverage comes from creating open-source tools and datasets. By building the fundamental infrastructure, they empower the entire scientific community—from academic labs to startups—to accelerate discovery.
  2. Data Is the New Microscope: The future of biology hinges on a tight feedback loop between generating novel, purpose-built datasets and training domain-specific AI models on them. This synergy is unlocking insights that were previously impossible.
  3. Virtual Biology Is the Next Frontier: Simulating biology computationally with "virtual cells" will become the new standard for research, enabling scientists to test riskier hypotheses faster and cheaper, dramatically compressing the timeline for major breakthroughs.
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Crypto Podcasts

December 31, 2025

2026 Predictions: BTC & ETH Hit Record Highs, TradFi Uses Solana: Bits + Bips

Unchained

Crypto
Key Takeaways:
  1. Capital is migrating from offshore exchanges to regulated US derivatives markets as the CME faces competition from Coinbase.
  2. Prioritize stablecoins with transparent reserve locations to avoid contagion where a bank failure triggers a crypto de-peg.
  3. Success depends on building utility-first infrastructure rather than chasing the ghost of 2021-style token launches.
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December 30, 2025

How Canton Network Was Built for Institutional Use in Crypto

The DCo Podcast

Crypto
Key Takeaways:
  1. The transition from speculation to utility. Capital is moving from crypto native games to real world efficiency gains.
  2. Prioritize infrastructure. Build or invest in protocols that prioritize liquidity and institutional compliance over short term retail hype.
  3. The next year will see the crypto casino fade as institutional rails like Canton Network enable the migration of trillions in traditional assets.
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December 30, 2025

What's The Trade For 2026?

1000x Podcast

Crypto
Key Takeaways:
  1. Geopolitical fracturing is replacing the single-hedge-fund-world. Capital is migrating from speculative "paper" assets to hard-capped commodities and privacy-preserving tech.
  2. Short the "zombie" alts. Create a basket of low-utility, high-FDV tokens from the previous cycle and pair them against long positions in Bitcoin and Monero.
  3. The market is punishing momentum-chasing and rewarding structural alignment. If you aren't positioned for a multipolar, high-inflation environment, you are exit liquidity for the sovereigns.
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December 30, 2025

What's Next For Crypto In 2026 | Kairos Research

Lightspeed

Crypto
Key Takeaways:
  1. The migration from subsidized security to fee-based sustainability. Capital is fleeing "fake money" inflation for real yield.
  2. Monitor Solana's BAM plugins for maker prioritization. This allows perps to offer tighter spreads than centralized exchanges.
  3. 2026 is the year of the "Real" app. The winners will be those who stop hoarding interest and start sharing it with their users.
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December 30, 2025

Landmark Regulation, ICOs, Downtober & Privacy: 2025 Crypto Year in Review (Part 2)

Unchained

Crypto
Key Takeaways:
  1. The Macro Shift: Regulatory moats are being built around stablecoins to protect bank deposits. This forces a migration toward "consortium" models like Stripe’s Tempo.
  2. The Tactical Edge: Audit market maker agreements to ensure protection against exchange API failures. Reliability is now a competitive advantage.
  3. 2026 looks like a liquidity-driven recovery. The "easy road" is over, but the infrastructure for the next cycle is finally being built by adults.
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December 29, 2025

HIP-3 and Markets by Kinetiq with Omnia | Livestream

0xResearch

Crypto
Key Takeaways:
  1. The Macro Trend: Vertical Integration. Protocols are moving from single-utility tools to full-stack financial ecosystems that own both the liquidity and the application layer.
  2. The Tactical Edge: Monitor HIP-3 auctions. Watch how new exchanges utilize Kinetic's infrastructure to bootstrap liquidity without issuing predatory new tokens.
  3. The Bottom Line: Kinetic is building the infrastructure for a post-Binance world where users own the venues they trade on. This matters for your roadmap because user-owned liquidity is the next major phase of DeFi growth.
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