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AI Podcasts

December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The AI era will disproportionately reward existing businesses that deeply integrate AI to create unassailable cost structures, not just new AI-native ventures.
  2. Builder/Investor Note: Seek out resilient "Act II" leaders who embrace the "and" business—growth, innovation, and profitability—and are willing to navigate public market scrutiny for long-term alignment.
  3. The "So What?": Over the next 6-12 months, expect market volatility to create opportunities to invest in disciplined companies leveraging AI for fundamental operational shifts, rather than just hype.
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December 15, 2025

The Renaissance of the American Factory | a16z 2026 Big Ideas

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next wave of industrial growth will come from applying manufacturing principles to large-scale infrastructure, not just consumer goods.
  2. Builder/Investor Note: Focus on companies that are standardizing designs and processes for physical assets, particularly those leveraging AI to navigate regulatory complexity and accelerate deployment.
  3. The "So What?": The rapid build-out of data centers is a live experiment for a broader industrial renaissance, providing a blueprint for how America can rebuild its capacity to build at scale over the next 6-12 months.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Implication: The "AI safety" narrative is shifting from content moderation to systemic security. Focus on hardening the entire AI ecosystem, not just restricting model outputs.
  2. Builder/Investor Note: Be wary of "AI security" products that claim to "secure the model" through guardrails. These are likely security theater. Invest in full-stack AI security solutions, red teaming services, and platforms that facilitate open-source adversarial research.
  3. The "So What?": The future of AI security is not about building higher walls around models, but about understanding and hardening the entire ecosystem in which they operate. Open collaboration and adversarial testing are the fastest paths to robust AI.
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December 15, 2025

Evolving Large Language Model Evaluation: Practices and Insights from the Swallow Project

Weights & Biases

AI
Key Takeaways:
  1. Strategic Implication: The quality and sophistication of LLM evaluation frameworks are now as critical as the models themselves. This is a foundational layer for AI progress.
  2. Builder/Investor Note: Builders must adopt adaptive evaluation. Investors should scrutinize how LLM performance is measured, not just the headline numbers.
  3. The "So What?": As LLMs gain complex reasoning and instruction-following abilities, evaluation frameworks that can accurately measure these capabilities will be essential for identifying true innovation and avoiding misallocated resources in the next 6-12 months.
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December 15, 2025

LLM Research and Development Initiatives at the National Institute of Informatics

Weights & Biases

AI
Key Takeaways:
  1. Sovereign AI is Real: Nations are investing in domestic AI capabilities to counter linguistic bias and ensure data control. This creates opportunities for specialized models and infrastructure.
  2. Builder's Edge: Meticulous parameter tuning, high-quality data curation, and innovative architectures like MoE are crucial for achieving top-tier LLM performance.
  3. The Agentic Future: AI agents are rapidly becoming indispensable tools in research and education, demanding robust, reliable, and culturally relevant LLM backbones.
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December 15, 2025

Coding Evals: From Code Snippets to Codebases – Naman Jain, Cursor

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: The future of AI code generation hinges on dynamic, robust evaluation systems that adapt to evolving model capabilities and detect sophisticated exploitation.
  2. Builder/Investor Note: Invest in or build evaluation infrastructure that incorporates dynamic problem sets, LLM-driven hack detection, and granular, human-centric metrics.
  3. The "So What?": Relying on static benchmarks is a losing game. The next 6-12 months will see a push towards more sophisticated, real-world-aligned evaluation methods, separating genuinely capable models from those that merely game the system.
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December 15, 2025

Building in the Gemini Era – Kat Kampf & Ammaar Reshi, Google DeepMind

AI Engineer

AI
Key Takeaways:
  1. Intent Over Implementation: The value in software creation shifts from low-level coding to clearly defining intent and design, with AI handling the technical execution.
  2. Rapid Prototyping: Builders can now rapidly prototype and deploy complex, full-stack applications, significantly compressing development cycles and lowering entry barriers.
  3. New Creator Economy: Expect a surge in non-technical creators building sophisticated applications, driving innovation in UI/UX and personalized content.
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December 15, 2025

The Renaissance of the American Factory | a16z 2026 Big Ideas

a16z

AI
Key Takeaways:
  1. Strategic Shift: The "factory-first" mindset is a strategic reorientation towards physical production, enabled by AI, extending beyond traditional manufacturing to all large-scale infrastructure.
  2. Builder/Investor Note: Focus on companies applying modular design, AI-driven process optimization, and automation to sectors like housing, energy, and mining. Data centers are a leading indicator for these trends.
  3. The "So What?": Rebuilding America's industrial capacity through these methods offers a competitive advantage, impacting defense, consumer goods, and commercial sectors in the next 6-12 months.
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December 13, 2025

Minimax M2 – Olive Song, MiniMax

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: The future of AI agents hinges on practical utility and adaptive reasoning, not just raw scale. Models that integrate expert feedback and iterative thinking will outperform those focused solely on benchmarks.
  2. Builder/Investor Note: Builders should prioritize robust generalization through diverse training perturbations. Investors should seek models that demonstrate real-world adoption and cost-effective scalability for multi-agent architectures.
  3. The So What?: The next 6-12 months will see a shift towards smaller, highly specialized, and deeply integrated AI models that function as reliable co-workers, driving efficiency in developer workflows and complex agentic tasks.
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Crypto Podcasts

December 19, 2025

Crypto 'Is Dead' - DATs: A Buying Opportunity? Plus: Figure's IPO & Trump's WLFI in Trouble

Unchained

Crypto
Key Takeaways:
  1. Strategic Implication: The crypto industry is moving beyond speculative cycles, driven by the integration of real-world assets and the pursuit of tangible efficiencies by both startups and traditional financial giants.
  2. Builder/Investor Note: Builders should prioritize utility and cost reduction for mainstream users, while investors must scrutinize projects for sustainable business models and genuine decentralization, rather than relying on hype or incentive schemes.
  3. The "So What?": Regulatory clarity, particularly around DeFi and asset classification, will shape the next 6-12 months, determining which projects thrive by truly delivering value and which struggle under increased scrutiny.
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December 18, 2025

If Ethereum and Solana Had a Baby, It Would Be Monad

The DCo Podcast

Crypto
Key Takeaways:
  1. Strategic Implication: Monad represents a significant bet on vertical scaling of Layer 1s, aiming to unlock a new class of high-performance DeFi applications by directly addressing core execution bottlenecks.
  2. Builder/Investor Note: Full EVM bytecode compatibility means existing Ethereum dApps can migrate with minimal changes, immediately benefiting from 10,000+ TPS and 1-second finality. This opens doors for high-frequency DeFi, on-chain order books, and complex AI/ML applications.
  3. The "So What?": If Monad delivers on its promises, it could validate a powerful alternative scaling path for crypto, shifting focus back to base-layer innovation and enabling decentralized finance to truly compete with centralized exchanges in performance and cost within the next 6-12 months.
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December 18, 2025

Hivemind: Crypto Is Dead with Dougie DeLuca

Empire

Crypto
Key Takeaways:
  1. Strategic Implication: The industry's future lies in seamless integration with the broader economy, making blockchain an invisible, value-adding layer for everyday products.
  2. Builder/Investor Note: Focus on projects solving real problems, demonstrating product-market fit in proven sectors (stablecoins, perps, token issuance), and prioritizing user experience over maximalist decentralization.
  3. The "So What?": The next 6-12 months will reward deep research and conviction in quality assets, as the market shifts from speculative narratives to tangible utility and real-world adoption.
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December 18, 2025

Why Gen Z Will Turn Everything Into a Market | Threadguy

Bankless

Crypto
Key Takeaways:
  1. Strategic Implication: The lines between traditional finance, crypto, and cultural markets will blur. "Internet markets" will encompass everything, driven by attention and mimetics.
  2. Builder/Investor Note: Focus on platforms that facilitate permissionless market creation and enhance the "spectacle" of trading. User experience that feels as native as social media will capture Gen Z's capital.
  3. The "So What?": Crypto's open, liquid, and attention-driven nature makes it the ultimate infrastructure for this new financial paradigm. The next decade will see an explosion of internet asset trading, with crypto at its core.
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December 18, 2025

Solana's Biggest Opportunity In 2026 | Dan Smith

Lightspeed

Crypto
Key Takeaways:
  1. Strategic Implication: Solana's focus on PropAMMs and perpetuals is a foundational shift, positioning it as a global financial hub rather than just a speculative playground. This creates a more sustainable revenue model for the chain.
  2. Builder/Investor Note: Builders should leverage Solana's market structure for innovative financial primitives. Investors must scrutinize tokenomics, especially the "two-asset model," and prioritize projects with transparent investor relations.
  3. The "So What?": The next 6-12 months will see a significant increase in onchain trading sophistication and volume on Solana, driven by PropAMMs and the expansion into perpetuals. This will attract more institutional capital and solidify Solana's role in global finance.
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December 18, 2025

🟦 Base Eco & Coinbase System Update Mega Stream

The Rollup

Crypto
Key Takeaways:
  1. Market Bifurcation: The crypto market is splitting. Protocols with strong FinTech distribution partnerships (the "DeFi mullets") will outpace those relying solely on crypto-native power users.
  2. Builder/Investor Note: Builders should prioritize Base App integration and AI-driven simplification. Investors should identify DeFi protocols securing these large-scale distribution deals and those building in tokenized RWAs and prediction markets.
  3. The "So What?": Coinbase's aggressive expansion into traditional assets, combined with Base App's creator-first, self-custodial "everything app" vision, signals a significant push for mainstream adoption. The next 6-12 months will see a race to onboard millions of new users and creators, fundamentally reshaping how we interact with finance and digital ownership.
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