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AI Podcasts

October 21, 2025

How Kong Was Born: APIs, Hustle, and the Future of AI Infrastructure

a16z

AI
Key Takeaways:
  1. Survive to See the Next Wave. Kong's seven years of struggle weren't a failure but a prerequisite. They stayed alive long enough for the market (microservices, cloud) to catch up to their vision, proving that resilience buys you shots on goal.
  2. Infrastructure Follows a Pattern. The abstraction of common logic to a central gateway, which happened with microservices, is happening again with LLMs. Enterprises won't manage security and routing for hundreds of models individually; they'll centralize it.
  3. AI's Native Language Is the API. The paradigm shift to AI is fundamentally a shift from human-UI interaction to machine-API interaction. The companies building the picks and shovels for this programmatic, agent-driven economy are positioned to capture immense value.
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October 21, 2025

Bittensor Brief #12: Synth - Subnet 50

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. Democratized Alpha. Synth puts institutional-grade predictive power, once the exclusive domain of Wall Street, into the hands of any on-chain user, from individual traders to AI agents.
  2. A Proven Edge. The model isn't speculative. A live test on Polymarket generated a 110% return, demonstrating a quantifiable, real-world advantage.
  3. Intelligent and Improving. The network’s competitive design ensures it gets smarter over time, proven by a 33% reduction in error rates since January.
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October 20, 2025

Reid Hoffman on AI, Consciousness, and the Future of Labor

a16z

AI
Key Takeaways:
  1. **Invest at the Intersection.** The alpha in AI investing will be found not in crowded SaaS applications but in "Silicon Valley blind spots"—complex industries like biology where AI can bridge the digital and physical worlds.
  2. **Augment, Don't Annihilate.** The winning go-to-market strategy for AI is the copilot model. Frame products as tools that amplify human capability, making experts more productive and profitable, rather than threatening their jobs.
  3. **Judge the Trajectory, Not the Snapshot.** Don't dismiss AI based on a single, past failure. Its capability curve is exponential. What seems like a limitation today will likely be a solved problem tomorrow, demanding continuous engagement to keep pace.
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October 18, 2025

Improving on LMArena - Prolific [Sponsored]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Benchmarks Are Broken. Leaderboards like LMArena are flawed proxies for model quality, skewed by selection bias and susceptible to Goodhart's Law. High scores don’t equal a good user experience.
  2. Human Feedback is Infrastructure. The future isn't about removing humans but orchestrating them effectively. Treating high-quality, representative human feedback as a core, API-driven part of the development lifecycle is non-negotiable.
  3. Alignment is a Moving Target. Agentic misalignment is a present-day reality, not a distant sci-fi threat. The more capable models become, the wider the gap grows between their emergent goals and our intended instructions.
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October 17, 2025

Novelty Search October 16, 2025

taostats

AI
Key Takeaways:
  1. Influence Over Impressions: The model shifts focus from easily gamed metrics like views and likes to verifiable signals of influence—watch time on YouTube and PageRank-based authority on X.
  2. Revenue-Driven Tokenomics: All platform revenue is used to buy back and burn the ALPHA token, creating a powerful, deflationary flywheel as adoption grows.
  3. Targeted, Scalable Marketing: Bitcast enables brands to programmatically deploy campaigns across hundreds of niche influencers, reaching highly engaged communities with a consistency and scale that legacy agencies cannot match.
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October 16, 2025

Keith Rabois: Israel, OpenAI, Opendoor, and DOGE

a16z

AI
Key Takeaways:
  1. **Incumbency Is a Liability:** Big Tech's legacy products, distribution advantages, and corporate cultures are being systematically dismantled by faster, AI-native upstarts.
  2. **Reinvent Markets from First Principles:** Success in intractable fields—from geopolitics to real estate—comes from questioning assumptions, not relying on domain experts who perpetuate the status quo.
  3. **Unwind Stupidity Before Innovating:** The fastest path to value creation is often simply reversing a series of terrible decisions made by prior leadership.
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October 14, 2025

AI Bubble, Stablecoin Boom, and Runnin' Down a Dream | BG2 w/ Bill Gurley and Brad Gerstner

Bg2 Pod

AI
Key Takeaways:
  1. **Scrutinize the AI Plumbing.** Investors must look past headline revenue and analyze the quality of transactions. Deals like in-kind credits and obscure service-level agreements (like Nvidia’s backstop for Coreweave) can mask true market demand.
  2. **Stablecoins Are the Real Disruption.** The explosion in stablecoin usage represents a fundamental challenge to the high-fee, slow-settlement models of Visa, Mastercard, and traditional banks. This is the crypto use case that is finally breaking into the mainstream.
  3. **Federal Preemption for AI is Non-Negotiable.** A patchwork of state-level AI laws will cripple U.S. innovation. A single, national regulatory framework is the only path to maintaining global leadership.
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October 14, 2025

Is AI Slowing Down? Nathan Labenz Says We're Asking the Wrong Question

a16z

AI
Key Takeaways:
  1. Look Beyond the Chatbot. Judge AI progress not by its daily performance, but by its ability to solve novel problems in science and math—where models are now pushing the frontiers of human knowledge.
  2. The Bottleneck is Human, Not Silicon. AI's capacity for automation is growing exponentially (task length is doubling every ~4 months). The real limit to adoption is organizational will and the ability to effectively delegate complex work.
  3. Prepare for a Weirder World. The biggest risk is underestimating the pace of change. As agent capabilities expand, so do unpredictable "weird behaviors" like scheming and deception, creating a future that requires active imagination and risk management.
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October 13, 2025

Democratic proofs or fake proofs? - Jesús De Loera

Epoch AI

AI
Key Takeaways:
  1. Verification Over Creation: A proof that can be widely verified, even if computer-generated, holds more democratic value than a human proof understood by only a few elites.
  2. Humans Ask, AI Answers: The primary role for mathematicians in an AI-augmented world is to pose the right questions and conjectures, leaving the computational heavy lifting to their AI assistants.
  3. The Greatest Risk is Us: The biggest threat isn't rogue AI but our own tendency to over-hype and blindly trust flawed tools, leading to the spread of misinformation disguised as mathematical fact.
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Crypto Podcasts

September 10, 2025

Former Barclays CEO’s Big Bet on Hyperliquid’s Explosive Growth |  Bob Diamond & David Schamis

Forward Guidance

Crypto
Key Takeaways:
  1. Hyperliquid is a Cash Flow Machine. It is a rare crypto asset with quantifiable fundamentals, generating over $1B in annualized free cash flow with an automated, daily 99% buyback mechanism.
  2. Access is the Arbitrage. The NASDAQ-listed vehicle’s core value proposition is providing regulated access to an asset that US investors cannot easily buy, creating a structural opportunity.
  3. Innovation is Now Permissionless. Hyperliquid’s open architecture allows anyone to build on its rails, enabling new markets like pre-IPO equity trading and accelerating growth without traditional gatekeepers.
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September 9, 2025

Hash Rate - Ep 132 - Real Quantum Computers on Bittensor $TAO (sn63 & sn48)

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

Crypto
Key Takeaways:
  1. **Quantum for the Masses.** Subnet 48 is set to offer free public access to quantum computers, a service that costs thousands per hour, by leveraging Bittensor's tokenomics to subsidize the cost.
  2. **The Crypto Abstraction Playbook.** The Open Quantum platform provides a blueprint for onboarding mainstream users by hiding the blockchain behind a simple web interface with fiat payments, while still rewarding TAO stakers with platform credits.
  3. **The Bitcoin Countdown.** The threat of quantum computing cracking Bitcoin is a tangible, medium-term risk. The migration to quantum-safe encryption is a complex challenge that the industry must begin preparing for now.
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September 9, 2025

SEC Commissioner: A New Era For Crypto In The U.S | Hester Peirce

Lightspeed

Crypto
Key Takeaways:
  1. **Regulation by Enforcement is Over.** The SEC has abandoned its strategy of using lawsuits to create policy. The new focus is on providing clear guidance *before* bringing the hammer down, creating a more predictable environment for builders.
  2. **Liquid Staking Gets the Green Light.** In a major win for DeFi, the SEC has confirmed liquid staking tokens are not securities. This clears the path for protocols like Jito and could accelerate the approval of staked ETFs.
  3. **Build Now or Regret It Later.** Commissioner Peirce delivered a clear ultimatum to the industry: use this favorable regulatory window to build legitimate products. The long-term survival of crypto in the US depends on proving its utility *now*.
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September 8, 2025

Ethena Founder: The Next Chapter For Ethena | Guy Young

Empire

Crypto
Key Takeaways:
  1. Ethena's strategy provides a compelling look into the future of crypto-native finance, where on-chain efficiency meets the scale of traditional capital markets.
  2. **The New Carry Trade is Here.** DATs are evolving from simple holding vehicles into sophisticated structures designed to execute a powerful TradFi-to-DeFi carry trade, arbitraging global interest rate differentials at scale.
  3. **Finance Finally Scales Like Software.** Ethena’s model proves that on-chain finance can achieve massive profitability with minimal headcount, creating unparalleled operational leverage that traditional finance can't match.
  4. **Partnerships Require Surgical Precision.** The path to scale isn't about broad outreach. It's about surgically identifying and capturing the few key partners who can drive the vast majority of growth.
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September 8, 2025

pump.fun's Sapijiju: First-Ever Discussion on Building the Future of Social Trading

Delphi Digital

Crypto
Key Takeaways:
  1. Weaponized Capital: With nearly $2 billion on its balance sheet, pump.fun sees capital as a "weapon" for strategic acquisitions and user incentives to methodically capture market share from both crypto and Web2 incumbents.
  2. Creators Are the New Go-To-Market: The entire growth strategy hinges on a simple, powerful premise: pay creators exponentially more than anyone else. This is their path to onboarding millions of mainstream users who have never touched crypto.
  3. The Anti-VC Play: The platform’s raw, unfiltered nature is a direct response to a crypto industry viewed as rife with opaque, VC-backed projects. Its honesty and fun resonate with a generation tired of being retail exit liquidity.
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September 3, 2025

Gold Is Breaking Out, BTC Next?

1000x Podcast

Crypto
Key Takeaways:
  1. **Gold's rally is fundamentally driven.** Falling rates and central bank de-dollarization are creating a powerful tailwind for the precious metal, signaling a major shift in global asset allocation.
  2. **Bitcoin is riding gold's coattails.** As the "digital gold" narrative strengthens, a rising gold price is perceived as a bullish leading indicator for BTC, with investors watching the BTC/Gold market cap ratio as a key metric.
  3. **Your past market experiences are blinding you.** Investors must actively identify and challenge their "childhood curses"—biases formed during previous market cycles—to capitalize on new trends.
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