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AI Podcasts

December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Pre-Training is the New Frontier: The next leap in AI capabilities, particularly for agentic systems, will come from fundamental advancements in pre-training, not just post-training tweaks.
  2. Builders & Investors: Focus on teams rethinking loss objectives, curating high-quality reasoning data, and developing dynamic benchmarks for agentic capabilities. Be wary of "agentic" claims that lack foundational pre-training innovation.
  3. The "So What?": Over the next 6-12 months, expect a push for new benchmarks and data strategies that explicitly train models for multi-step planning, long-form reasoning, and error recovery, moving beyond simple next-token prediction.
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December 16, 2025

What We Learned Deploying AI within Bloomberg’s Engineering Organization – Lei Zhang, Bloomberg

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: AI fundamentally changes the economics of software development. Organizations must re-evaluate what constitutes "high-quality" engineering and adapt their processes.
  2. Builder/Investor Note: Prioritize platforms that provide guardrails and guidance for AI tool usage, focusing on deterministic verification and robust testing. Uncontrolled AI deployment risks technical debt.
  3. The "So What?": The next 6-12 months will see a bifurcation: companies that strategically integrate AI into their engineering culture and platforms will gain significant efficiency, while those that don't will struggle with quality and adoption.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Workflow Automation is the New Frontier: The real value of AI in developer tools comes from orchestrating entire workflows, not just individual point solutions.
  2. Embed for Adoption: Tools must integrate seamlessly into existing workflows and IDEs (like Cursor) to achieve high usage.
  3. Support as a Code-Shipping Powerhouse: Empowering non-traditional roles with AI-driven code generation leverages their unique, real-time context, creating significant operational leverage.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Semantic Shift: The future of AI in code moves from text generation to deep semantic understanding and execution simulation.
  2. Builder Opportunity: Develop next-generation debugging tools and code agents that leverage internal simulation for faster, more efficient development cycles.
  3. Investor Focus: Prioritize models and platforms that demonstrate explicit execution modeling, as this capability will redefine software development and create new market leaders.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Infrastructure Shift: AI-driven kernel optimization addresses a critical bottleneck in scaling AI compute, enabling more efficient use of diverse hardware.
  2. Builder/Investor Note: Focus on solutions with robust, hardware-verified performance metrics and a clear human-in-the-loop strategy. AI is a powerful tool for automating optimization, not a magic bullet for novel algorithmic breakthroughs.
  3. The "So What?": This technology frees expert engineers from tedious optimization, allowing them to focus on higher-level research and truly innovative algorithmic design, accelerating the pace of AI development in the next 6-12 months.
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December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The era of "free money" inflated the number of perceived compounders; a return to positive real rates demands a sharper focus on businesses demonstrating genuine financial discipline and competitive advantage.
  2. Builder/Investor Note: Seek out "Act 2" entrepreneurs and companies that can leverage AI to transform existing physical or IP-based advantages, not just create new AI products. Be prepared to buy more when market sentiment turns negative on strong businesses.
  3. The "So What?": The next 6-12 months will differentiate companies that merely adopt AI from those that strategically integrate it to build durable, uncatchable cost and distribution advantages.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. The Future of Policing is Intelligent: Integrating AI, drones, and smart cameras creates a precise, accountable, and safer policing model for both officers and communities.
  2. Invest in the "How": Builders and investors should focus on technologies that enhance certainty of capture, streamline judicial processes, and support public-private partnerships to modernize urban safety infrastructure.
  3. Safety Fuels Mobility: Eliminating crime is not just about law enforcement; it's about restoring the fundamental safety required for economic mobility and a functional society.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade's value will accrue to those building foundational AI infrastructure and the "invisible layers" that connect intelligent systems.
  2. Builder/Investor Note: Focus capital and talent on core AI models, specialized domain intelligence, and the underlying computational fabric. Superficial applications risk rapid commoditization.
  3. The So What?: This is the defining period for the architecture of global intelligence. Participation now determines future influence and relevance.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Shift: AI security must move beyond superficial guardrails to a full-stack, offensive red-teaming approach that accounts for the expanding attack surface of AI agents and their tool access.
  2. Builder/Investor Note: Builders should prioritize integrating offensive security early in development. Investors should be wary of "security theater" and favor solutions that embrace open-source collaboration and address the entire AI application stack.
  3. The "So What?": The accelerating pace of AI development means static security solutions will quickly become obsolete. Proactive, community-driven, and full-stack security research is essential for navigating the next 6-12 months of AI evolution.
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Crypto Podcasts

January 31, 2026

LIVE: Gold vs. Bitcoin & MoltBook | 0xResearch

0xResearch

Crypto
Key Takeaways:
  1. The Macro Shift: Geopolitical tensions and economic uncertainty are driving a global re-allocation of capital, with Eastern wealth increasingly favoring hard assets and localized crypto rails. This challenges Western-centric market analysis and demands a broader, more nuanced view of global finance.
  2. The Tactical Edge: Cultivate deep domain expertise and critical thinking, using AI as an amplification tool, not a replacement for learning. Focus on areas where human judgment, taste, and the ability to translate AI insights into real-world value remain irreplaceable.
  3. The Bottom Line: The next 6-12 months will see continued divergence in global capital flows and accelerating AI integration. Investors must track opaque Eastern market signals, while builders should prioritize AI applications that augment human capability rather than simply automate, ensuring their skills remain relevant in an increasingly AI-driven world.
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January 30, 2026

The Fed Is Background Noise While Markets Reprice Reality | Weekly Roundup

Forward Guidance

Crypto
Key Takeaways:
  1. The Macro Shift: Monetary Escapism: As fiat debases and geopolitical tensions rise, capital is rotating from traditional tech to hard-capped assets and AI infrastructure.
  2. The Tactical Edge: Reallocate Capital: Prioritize real assets and cyclical commodities (gold, silver, oil, copper) while selectively shorting overvalued software companies facing AI disruption and increasing capital expenditures.
  3. The Bottom Line: The market is re-pricing value based on true scarcity and capital intensity. Position for a volatile environment where traditional narratives fail, and tangible assets or essential AI infrastructure dictate returns.
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January 29, 2026

The Most Underrated Chain: Celo’s Surprising Traction Around the World

Bankless

Crypto
Key Takeaways:
  1. The migration of the $3.2 quadrillion FX market to transparent, 24/7 blockchain rails.
  2. Build consumer-facing apps that utilize the phone-number-as-identity standard to capture the next 100 million users.
  3. Celo is the leading laboratory for real-world crypto adoption, proving that the Global Venmo dream is finally scaling.
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January 29, 2026

What If DOGE Actually Becomes Real Money?

The DCo Podcast

Crypto
Key Takeaways:
  1. The transition from speculative assets to utility-based currencies.
  2. Integrate low-fee payment rails like the Dogecoin GigaWallet to capture micro-transaction volume.
  3. Dogecoin is the dark horse of the next financial era because it prioritizes being used over being hoarded.
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January 28, 2026

LIVE: BITGO IPO, HIP-3, KNTQ | 0xResearch

0xResearch

Crypto
Key Takeaways:
  1. Capital no longer distinguishes between AI stocks and rare metals. Investors treat these as a single risk-on bucket settled on-chain.
  2. Monitor Hyperliquid deployers. Identify protocols moving from passive yield to active market-making to capture the next commodity rotation.
  3. The next year will favor platforms providing access to diverse asset classes. Pure crypto protocols must adapt or lose mindshare to trade everything venues.
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January 26, 2026

Metals Alt Season, Catchup Trades, Bitcoin vs Gold, Crypto Is Dead

1000x Podcast

Crypto
Key Takeaways:
  1. The Macro Transition: Hard Asset Migration. As fiat currencies lose purchasing power, capital moves into finite assets, starting with Gold and Bitcoin before trickling down to Silver and Ethereum.
  2. The Tactical Edge: Buy the Laggard. Identify assets with strong fundamentals that have underperformed the market leader by more than 30%.
  3. The Bottom Line: The catchup trade is the most profitable strategy when the primary leaders are consolidating.
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