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AI Podcasts

May 30, 2025

Novelty Search May 29, 2025

taostats

AI
Key Takeaways:
  1. Democratization Unleashed: Subnet 17 radically lowers barriers to 3D content creation, empowering indie developers and non-artists.
  2. Gaussian Splats are Hot: This representation is emerging as a key technology for fast, high-fidelity 3D AI, and Subnet 17 is at the forefront.
  3. Web2 Validation is Key: Partnerships like the Unity "verified solution" status signal BitTensor's growing real-world utility and credibility, presenting opportunities for miners and the TAO ecosystem.
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May 30, 2025

SN17 - 404GEN :: Decentralized AI generated 3D assets

Opentensor Foundation

AI
Key Takeaways:
  1. Unlocking Creative Potential: 404GEN radically lowers barriers to 3D content creation, enabling faster iteration and new forms of interactive media previously unfeasible for smaller teams or individuals.
  2. Gaussian Splats are Ascendant: This representation is emerging as a powerful alternative for 3D AI, and 404GEN is at the forefront of its practical application and tooling.
  3. BitTensor's Competitive Edge Shines: The subnet's rapid quality improvement and the innovative ELO validation system highlight BitTensor's power to incentivize and coordinate decentralized intelligence towards state-of-the-art results.
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May 30, 2025

Hey Tech, Come to Healthcare

a16z

AI
Key Takeaways:
  1. **Build for Behavior Change:** The biggest wins will come from engaging consumers and enabling sustainable health behaviors, an area where tech excels.
  2. **AI is the Leapfrog:** Healthcare can jump directly to AI-driven solutions, bypassing clunky legacy software, especially for service-oriented tasks.
  3. **The Trillion-Dollar Prize is Real:** Whether through full-stack "payvider" models or horizontal platforms, the path to becoming the world's largest company runs through transforming the consumer healthcare experience.
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May 29, 2025

Building a DePIN-powered Shazam for Media with Rumi | Niko Cunningham and Mateusz Poreda

Proof of Coverage Media

AI
Key Takeaways:
  1. **Decentralized Analytics:** Rumi’s DePIN model democratizes media intelligence, offering far richer and more granular data than traditional players like Nielsen.
  2. **Context is King:** The "Shazam for media" capability will fuel a new generation of AI agents and interactive experiences, making media deeply engaging.
  3. **Investor Signal:** The $5M pre-seed (EV3, A16Z CSX) and early traction with industry players like Tivision validate Rumi's approach and market potential.
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May 29, 2025

Beyond Leaderboards: LMArena’s Mission to Make AI Reliable

a16z

AI
Key Takeaways:
  1. Reliability Demands Real-Time, Human-Centric Testing: Static benchmarks are dead. AI reliability for complex tasks requires continuous evaluation based on diverse, subjective human preferences in real-world scenarios.
  2. Crowd-Sourced Evaluation Outperforms Insular Expertise: The "wisdom of the crowd," as captured by LMArena, provides a more robust and representative measure of AI performance than siloed expert opinions, preventing narrow value-encoding.
  3. Personalized Evaluation is the Next Frontier: Technologies like "Prompt to Leaderboard" show the potential for highly granular, cost-effective, and personalized AI model selection, maximizing utility for individual users and specific tasks.
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May 28, 2025

Rick Rubin: Vibe Coding is the Punk Rock of Software

a16z

AI
Key Takeaways:
  1. Embrace AI as a Co-Creator: Leverage AI to democratize creation and rapidly iterate, but remember the unique human element—your distinct point of view and intuition—is irreplaceable.
  2. Authenticity Over Algorithm: Whether you're an artist or an entrepreneur, genuine connection comes from unwavering commitment to your core vision, not by chasing fleeting trends or assumed audience desires.
  3. Question Everything, Especially "Answers": Cultivate a mindset of curiosity and critical thinking. AI can provide answers, but true insight comes from deeply engaging with questions and understanding that knowledge is ever-evolving.
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May 27, 2025

7 More Healthy Years: What We Can Learn from Super Agers

a16z

AI
Key Takeaways:
  1. Embrace AI-Powered Prevention: AI's capacity to synthesize vast health data will redefine personalized risk assessment and early intervention, moving us beyond one-size-fits-all healthcare.
  2. Target the "Big Three" Early: Focus on preventing cancer, cardiovascular disease, and neurodegenerative conditions by leveraging their long incubation periods for proactive interventions.
  3. Leverage New Therapeutic Frontiers: Groundbreaking drug classes like GLP-1s and rapid advancements in immunotherapy offer unprecedented tools to combat and, crucially, prevent major diseases.
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May 27, 2025

TAOFU's Mikel & Mitch: Enabling Capital Formation for Subnets on Bittensors $10B+ Network

Delphi Digital

AI
Key Takeaways:
  1. Democratized Subnet Funding: TAOFU’s SNS model allows subnet creators to raise capital without diluting their core emission-earning potential, fostering more shots on goal for AI innovation on Bittensor.
  2. Investor Access & Liquidity: For investors, TAOFU provides a clear mechanism (SNS tokens and an integrated DEX) to invest in early-stage Bittensor subnets and gain liquidity, previously a closed-off and opaque process.
  3. Curated Quality: TAOFU’s permissioned approach and focus on sustainable value capture (with plans for a curator model) aim to filter for high-quality projects, protecting investors while nurturing promising AI ventures within Bittensor.
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May 26, 2025

Has AI Revived the DePIN Sector? | Dmitriy Berenzon

0xResearch

AI
Key Takeaways:
  1. AI is DePIN's Demand Catalyst: The need for affordable AI compute is breathing new life and tangible demand into decentralized infrastructure.
  2. Value Accrual & Revenue are King: For DePIN tokens to thrive in liquid markets, clear mechanisms for value flow-through from opco revenue to the token are non-negotiable; "ARR is the new TVL."
  3. Distribution Trumps Decentralization (for now): Crypto-native solutions, especially in payments, must crack the distribution code or risk being outmaneuvered by Web2 incumbents leveraging their massive user bases.
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Crypto Podcasts

May 19, 2025

The State of Venture Today | Roundup Clip

Bell Curve

Crypto
Key Takeaways:
  1. LP Scrutiny Intensifies: Expect smaller fundraises for many VCs, especially in crypto, as LPs demand real returns (DPI) and, for crypto, regulatory certainty.
  2. Endowment Exodus Looms: Yale's $6B private equity sale signals a potential LP supply shock as other endowments may follow suit due to tax changes and liquidity needs.
  3. Elite VCs Consolidate Power: Capital will increasingly flow to the top 5-10 VC firms, particularly those with AI expertise, hastening the decline of underperformers.
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May 19, 2025

The Bull Case For Ethereum | Ryan Berckmans & Tom Dunleavy

Empire

Crypto
Key Takeaways:
  1. ETH's Valuation Paradigm Shift: Value ETH based on Total Value Secured (TVS), not diminishing transaction fees, as it aims to secure trillions in global assets.
  2. L1+L2 is the Winning Formula: Ethereum's strategy of scaling L1 alongside a diverse L2 ecosystem (offering political/business model diversity) is designed to onboard the world.
  3. Coordination & BD are Crucial: Renewed focus on cohesive narrative, business development (like Etherealize), and community alignment are vital to executing Ethereum's ambitious roadmap.
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May 19, 2025

The Genius Behind the Biggest Crypto Exchange in the Sonic Ecosystem

blocmates.

Crypto
Key Takeaways:
  1. Performance is Paramount: Sonic's best-in-class EVM performance is a non-negotiable foundation for ambitious DeFi protocols.
  2. Organic Traction Trumps Hype: Sonic's user-driven ecosystem is cultivating genuine DeFi engagement and sustainable innovation.
  3. AI Will Onboard the Masses: Natural language AI interfaces are set to revolutionize crypto accessibility, making it usable for everyone.
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May 19, 2025

Arthur Hayes: Money Printing & The Crypto Bet

Bankless

Crypto
Key Takeaways:
  1. Brace for Capital Controls: The US is likely to implement capital controls over politically unpalatable tariffs to rebalance its economy, fundamentally changing global capital flows.
  2. Money Printing is Non-Negotiable: Regardless of political rhetoric, the US will print money to manage the fallout from capital flight and fund government spending, massively benefiting hard assets.
  3. Bitcoin & Gold are Your Life Rafts: In an era of devaluing fiat and financial repression, Bitcoin and gold are critical for wealth preservation and growth. Ditch long-term bonds.
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May 19, 2025

Logan Allen: Nockchain's Global Competition for Useful ZK Proof of Work Miners Kicks Off

Delphi Digital

Crypto
Key Takeaways:
  1. ZKPoW is a Novel Force: Nockchain's ZK Proof of Work directly builds valuable ZK proving capacity, turning mining into a productive, network-enhancing activity.
  2. Hardware Revolution Looms: The mining competition will drive innovation in ZK-specific hardware (FPGAs, ASICs for polynomial math), creating a new hardware market distinct from Bitcoin's.
  3. Intent-Driven Future: Nockchain's architecture points towards a future of composable "micro-apps" and verifiable services, where on-chain logic focuses on proof verification, potentially enabling new decentralized AI/ML applications and "computational commodities."
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May 18, 2025

Weimar America: The Inflation Spiral Has Begun

Forward Guidance

Crypto
Key Takeaways:
  1. **Fiscal Dominance is Here:** Government spending, not just Fed policy, is the primary driver of the current inflationary pressures and will likely lead to an 8% GDP deficit.
  2. **Prepare for Intervention:** Expect capital controls (like remittance taxes) and yield curve control as governments grapple with the consequences of their spending.
  3. **Store-of-Value is King:** In an environment where traditional savings (e.g., 4% on bonds) can't match 15% inflation in essential costs, assets like tech stocks and Bitcoin become non-negotiable for wealth preservation.
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