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AI Podcasts

December 4, 2025

Real On-Chain Agents? How Talus Solves What Crypto-AI Got Wrong

The DCo Podcast

AI
Key Takeaways:
  1. On-Chain Execution is Crucial: True crypto AI requires AI agents that operate entirely on-chain to maintain decentralization, verifiability, and auditability.
  2. Monetization is Key: For sustainable AI adoption, clear and viable business models are essential to drive value back to the creators and incentivize participation.
  3. Entertainment as a Catalyst: Leveraging entertainment through agent-versus-agent competitions can drive adoption and demonstrate the earning potential of AI agents, fostering a new AI entertainment economy.
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December 1, 2025

The $700 Billion AI Productivity Problem No One's Talking About

a16z

AI
Key Takeaways:
  1. Measure Usage, Not Just Spend. The biggest failure in enterprise AI is tracking software purchases as a proxy for progress. The focus must shift to measuring actual tool usage correlated with output.
  2. Solve for Fear, Not Features. Employee adoption hinges on psychological safety. The most powerful tools will fail if users are afraid of looking incompetent or getting fired for making a mistake.
  3. Competition Drives Augmentation, Not Unemployment. The "AI will take our jobs" narrative is a red herring. Companies will reinvest AI-driven productivity gains to crush competitors, not just to cut headcount.
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November 28, 2025

How OpenAI Builds for 800 Million Weekly Users: Model Specialization and Fine-Tuning

a16z

AI
Key Takeaways:
  1. **The "One Model" Thesis Is Dead.** The future belongs to a portfolio of specialized models. This creates distinct opportunities for both foundational labs and companies that can leverage proprietary data to build best-in-class models for niche applications.
  2. **Data Is the Ultimate Differentiator.** Reinforcement learning fine-tuning elevates proprietary data from a simple input for RAG systems to the core ingredient for building a defensible, state-of-the-art product.
  3. **Agents Will Specialize.** The agent ecosystem is bifurcating into two primary types: open-ended, creative agents for knowledge work and deterministic, procedural agents designed for enterprise automation where reliability and adherence to standard operating procedures are critical.
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November 27, 2025

The AI Economy Is Leaving Labor Behind | Weekly Roundup

Forward Guidance

AI
Key Takeaways:
  1. Politics Will Trump Tech. Expect a policy pivot ahead of the 2024 election. The administration’s singular focus on AI stimulus is creating populist backlash, forcing a shift toward policies that support the broader labor market to secure votes.
  2. The AI Trade Is Evolving. The "Mag 7" may soon become regulated utilities. The next wave of winners will be legacy companies that successfully integrate AI to boost margins and the overlooked players in the AI supply chain, such as power and commodity providers.
  3. Prepare for a New Monetary Regime. The era of "QE Infinity" is ending. A post-Powell Fed is expected to move credit creation from its own balance sheet back to commercial banks, using deep rate cuts and deregulation to stimulate the economy.
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November 26, 2025

AI Is Ushering in an Entirely New Economic Paradigm | Jordi Visser

Forward Guidance

AI
Key Takeaways:
  1. AI Demand Is Not Cyclical; It's Infinite. Forget boom-and-bust. The mission to solve humanity's greatest problems—from disease to space travel—creates limitless demand for intelligence, underpinning a durable, multi-decade investment cycle.
  2. Scrap GDP; Watch Profit Margins. The widening chasm between the astronomical profit margins of tech companies and the rest of the economy is the single most important macroeconomic signal today.
  3. Bitcoin Is the Apex Predator of Moats. In a world where AI can replicate any business model, the only defensible moats are those built on time-tested belief and mathematical scarcity. Bitcoin is the emerging winner for the digital age.
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November 26, 2025

Epoch AI webinar: Inside the Frontier Data Centers hub

Epoch AI

AI
Key Takeaways:
  1. AI's Physical Footprint is Astronomical: Individual AI data centers are now multi-billion dollar megaprojects, with construction timelines accelerating to as little as one year for a gigawatt-scale facility.
  2. Power is a Solvable Problem, Not a Hard Cap: AI firms will pay whatever it takes to secure electricity, making power costs a secondary concern to the price of GPUs. The real constraint is getting chips, not watts.
  3. Open-Source Intelligence Unveils All: By combining satellite imagery, public permits, and news reports, the physical expansion of the AI industry can be tracked in near real-time, providing unprecedented transparency.
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November 24, 2025

The 2045 Superintelligence Timeline: Epoch AI’s Data-Driven Forecast

a16z

AI
Key Takeaways:
  1. AI Isn't a Bubble; It's a Buildout. The market is rational. Massive spending is backed by real revenue from inference. The true bottleneck is the speed at which capital can be deployed to build city-sized data centers.
  2. Brace for Economic Whiplash. A sudden, AI-driven unemployment spike is the most likely trigger for massive government intervention. The political response will be swift, decisive, and potentially radical.
  3. Superintelligence is a Hardware Problem. The path to 2045 runs through physical infrastructure. Progress is gated by the brute-force economics of building data centers, not a quest for a magical algorithm.
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November 23, 2025

"I Invented the Transformer. Now I'm Replacing It."

Machine Learning Street Talk

AI
Key Takeaways:
  1. **Escape the Architecture Lottery.** The inertia behind Transformers is immense. A new model must be demonstrably superior across the board to justify a paradigm shift.
  2. **Nature's Algorithms are the Next Frontier.** The CTM proves that biologically-inspired principles like neuron synchronization can unlock powerful capabilities like adaptive computation and better calibration naturally.
  3. **Reasoning is Deeper Than Scaling.** The Sudoku Bench benchmark shows that current SOTA models cannot perform the creative, nuanced reasoning humans do. Brute-force scaling has hit a wall against truly complex problems.
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November 20, 2025

AI Is Eating Your Data: NYT vs OpenAI, Smart Home Surveillance, and Digital Feudalism

The People's AI

AI
Key Takeaways:
  1. Your Data is the New Oil, and You're Giving It Away. Every smart device, social media post, and email you create is a valuable asset used to build multi-billion dollar AI empires, yet you receive no compensation.
  2. The Creator Economy is Facing an Existential Threat. The outcome of lawsuits like *NYT vs. OpenAI* will determine whether creative work remains intellectual property or becomes free raw material for AI, potentially decimating entire professions.
  3. Reclaim Your Digital Sovereignty. Losing control of your data isn't just a privacy issue; it's a slide into "digital feudalism." The podcast champions decentralized technologies as a tool to break these data monopolies and reassert individual ownership.
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Crypto Podcasts

March 6, 2025

Beyond Bitcoin: What Tokens Should Be in the U.S. Crypto Reserve?

Unchained

Crypto

Key Takeaways:

  • 1. Bitcoin and Ethereum are prime candidates for a U.S. crypto reserve due to their size and decentralization.
  • 2. The U.S. must address regulatory clarity to retain and attract top crypto talent.
  • 3. Prioritizing U.S.-made crypto assets can bolster domestic innovation and maintain technological leadership.
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March 5, 2025

Bits + Bips: Why a US Strategic Crypto Reserve Doesn’t Even Make Sense

Unchained

Crypto

Key Takeaways:

  • 1. Trump's crypto reserve proposal has united the crypto community in skepticism, questioning its strategic and economic rationale.
  • 2. Economic indicators point to a potential slowdown, with geopolitical tensions further complicating market outlooks.
  • 3. Stablecoins and institutional adoption are pivotal in the evolving crypto landscape, offering both opportunities and challenges.
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March 5, 2025

Jim Bianco: Is Trump Trying to Wreck the Economy?

Bankless

Crypto

Key Takeaways:

  • 1. Trump's policies are reshaping the economic landscape, with significant implications for both traditional and crypto markets.
  • 2. The creation of a crypto strategic reserve introduces new dynamics, but also risks undermining the decentralized ethos of crypto.
  • 3. Tariffs are a double-edged sword, offering potential benefits in trade negotiations but posing risks to economic stability.
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March 5, 2025

Yat Siu on East vs. West Culture, Neo-Capitalism, and Onchain Property Rights

The Rollup

Crypto

Key Takeaways:

  • 1. The cultural divide between East and West impacts the adoption and perception of crypto and digital ownership.
  • 2. Institutional involvement is reshaping the crypto landscape, offering new opportunities for growth and stability.
  • 3. The gaming industry is poised for a resurgence, driven by major releases and the integration of blockchain technology.
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March 4, 2025

How Berachain Became One of the Most Popular Blockchains

Unchained

Crypto

Key Takeaways:

  • 1. Berachain's innovative Proof of Liquidity model aligns incentives for liquidity and security, driving ecosystem growth.
  • 2. The blockchain's culture and community engagement are central to its success, creating a unique and appealing environment.
  • 3. Despite initial criticisms, Berachain's focus on long-term value and community-driven growth positions it for continued success.
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March 4, 2025

The Evolution of Alt Seasons | Tolks & zkMike

0xResearch

Crypto

Key Takeaways:

  • 1. The crypto market is heavily influenced by macroeconomic factors, making it crucial for investors to stay informed about broader economic trends.
  • 2. Alt seasons have transformed, with opportunities now more nuanced and often tied to on-chain activities.
  • 3. AI-driven tokens like Grass offer promising investment opportunities due to their robust business models and the increasing demand for real-time data.
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