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AI Podcasts

May 30, 2025

SN17 - 404GEN :: Decentralized AI generated 3D assets

Opentensor Foundation

AI
Key Takeaways:
  1. Unlocking Creative Potential: 404GEN radically lowers barriers to 3D content creation, enabling faster iteration and new forms of interactive media previously unfeasible for smaller teams or individuals.
  2. Gaussian Splats are Ascendant: This representation is emerging as a powerful alternative for 3D AI, and 404GEN is at the forefront of its practical application and tooling.
  3. BitTensor's Competitive Edge Shines: The subnet's rapid quality improvement and the innovative ELO validation system highlight BitTensor's power to incentivize and coordinate decentralized intelligence towards state-of-the-art results.
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May 30, 2025

Hey Tech, Come to Healthcare

a16z

AI
Key Takeaways:
  1. **Build for Behavior Change:** The biggest wins will come from engaging consumers and enabling sustainable health behaviors, an area where tech excels.
  2. **AI is the Leapfrog:** Healthcare can jump directly to AI-driven solutions, bypassing clunky legacy software, especially for service-oriented tasks.
  3. **The Trillion-Dollar Prize is Real:** Whether through full-stack "payvider" models or horizontal platforms, the path to becoming the world's largest company runs through transforming the consumer healthcare experience.
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May 29, 2025

Building a DePIN-powered Shazam for Media with Rumi | Niko Cunningham and Mateusz Poreda

Proof of Coverage Media

AI
Key Takeaways:
  1. **Decentralized Analytics:** Rumi’s DePIN model democratizes media intelligence, offering far richer and more granular data than traditional players like Nielsen.
  2. **Context is King:** The "Shazam for media" capability will fuel a new generation of AI agents and interactive experiences, making media deeply engaging.
  3. **Investor Signal:** The $5M pre-seed (EV3, A16Z CSX) and early traction with industry players like Tivision validate Rumi's approach and market potential.
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May 29, 2025

Beyond Leaderboards: LMArena’s Mission to Make AI Reliable

a16z

AI
Key Takeaways:
  1. Reliability Demands Real-Time, Human-Centric Testing: Static benchmarks are dead. AI reliability for complex tasks requires continuous evaluation based on diverse, subjective human preferences in real-world scenarios.
  2. Crowd-Sourced Evaluation Outperforms Insular Expertise: The "wisdom of the crowd," as captured by LMArena, provides a more robust and representative measure of AI performance than siloed expert opinions, preventing narrow value-encoding.
  3. Personalized Evaluation is the Next Frontier: Technologies like "Prompt to Leaderboard" show the potential for highly granular, cost-effective, and personalized AI model selection, maximizing utility for individual users and specific tasks.
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May 28, 2025

Rick Rubin: Vibe Coding is the Punk Rock of Software

a16z

AI
Key Takeaways:
  1. Embrace AI as a Co-Creator: Leverage AI to democratize creation and rapidly iterate, but remember the unique human element—your distinct point of view and intuition—is irreplaceable.
  2. Authenticity Over Algorithm: Whether you're an artist or an entrepreneur, genuine connection comes from unwavering commitment to your core vision, not by chasing fleeting trends or assumed audience desires.
  3. Question Everything, Especially "Answers": Cultivate a mindset of curiosity and critical thinking. AI can provide answers, but true insight comes from deeply engaging with questions and understanding that knowledge is ever-evolving.
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May 27, 2025

7 More Healthy Years: What We Can Learn from Super Agers

a16z

AI
Key Takeaways:
  1. Embrace AI-Powered Prevention: AI's capacity to synthesize vast health data will redefine personalized risk assessment and early intervention, moving us beyond one-size-fits-all healthcare.
  2. Target the "Big Three" Early: Focus on preventing cancer, cardiovascular disease, and neurodegenerative conditions by leveraging their long incubation periods for proactive interventions.
  3. Leverage New Therapeutic Frontiers: Groundbreaking drug classes like GLP-1s and rapid advancements in immunotherapy offer unprecedented tools to combat and, crucially, prevent major diseases.
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May 27, 2025

TAOFU's Mikel & Mitch: Enabling Capital Formation for Subnets on Bittensors $10B+ Network

Delphi Digital

AI
Key Takeaways:
  1. Democratized Subnet Funding: TAOFU’s SNS model allows subnet creators to raise capital without diluting their core emission-earning potential, fostering more shots on goal for AI innovation on Bittensor.
  2. Investor Access & Liquidity: For investors, TAOFU provides a clear mechanism (SNS tokens and an integrated DEX) to invest in early-stage Bittensor subnets and gain liquidity, previously a closed-off and opaque process.
  3. Curated Quality: TAOFU’s permissioned approach and focus on sustainable value capture (with plans for a curator model) aim to filter for high-quality projects, protecting investors while nurturing promising AI ventures within Bittensor.
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May 26, 2025

Has AI Revived the DePIN Sector? | Dmitriy Berenzon

0xResearch

AI
Key Takeaways:
  1. AI is DePIN's Demand Catalyst: The need for affordable AI compute is breathing new life and tangible demand into decentralized infrastructure.
  2. Value Accrual & Revenue are King: For DePIN tokens to thrive in liquid markets, clear mechanisms for value flow-through from opco revenue to the token are non-negotiable; "ARR is the new TVL."
  3. Distribution Trumps Decentralization (for now): Crypto-native solutions, especially in payments, must crack the distribution code or risk being outmaneuvered by Web2 incumbents leveraging their massive user bases.
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May 26, 2025

Chatbot platforms might replace social media

Machine Learning Street Talk

AI
Key Takeaways:
  1. AI Companionship is Exploding: Millions are already deeply engaged with AI for emotional connection, and this is just the beginning as technology like GPT-4o normalizes it.
  2. Lean Engineering Can Win: Chai's success with a tiny, hyper-talented team and innovative techniques like model blending proves that massive VC-backed operations aren't the only path to scale in AI.
  3. The Next Social Platform Might Be AI: As AI offers more active, personalized, and consequence-free social interaction, it could very well become the dominant way people connect, potentially supplanting traditional social media.
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Crypto Podcasts

March 17, 2025

How Arbitrum is Pushing the Limits | Steven Goldfeder

0xResearch

Crypto

Key Takeaways:

  • 1. Timeboost could reshape the MEV landscape on Arbitrum, benefiting both regular users and the chain itself.
  • 2. Interoperability hinges on improving user experience, not just on developing complex technical solutions.
  • 3. Arbitrum’s long-term vision and commitment to ecosystem neutrality are key differentiators in the competitive L2 market.
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March 17, 2025

The State Of Crypto Lending | Membrane Labs

Empire

Crypto

Key Takeaways:

  • 1. While the crypto lending landscape has evolved since 2022, with improved risk management and new players, systemic risks remain.
  • 2. The convergence of centralized and decentralized finance creates new opportunities but also introduces novel challenges and potential vulnerabilities.
  • 3. Custodians stepping into lending services, coupled with increased regulatory clarity, could unlock significant growth in the crypto lending market.
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March 17, 2025

How Mode Network is the Ultimate Breeding Ground for the Cross Section of Crypto and AI | Explained

blocmates.

Crypto

Key Takeaways:

  • 1. Mode Network's focus on user experience, AI integration, and robust data infrastructure positions it as a promising platform for DeFi mass adoption.
  • 2. The innovative veTokenomics model aligns incentives and empowers community governance, fostering a thriving ecosystem.
  • 3. The convergence of DeFi and AI has the potential to unlock new financial opportunities and reshape the way users interact with blockchain technology.
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March 14, 2025

Crypto’s Next Chapter: Who Thrives and Who Folds? | Roundup

Bell Curve

Crypto

Key Takeaways:

  • 1. The crypto market is transitioning from speculative gains to sustainable growth, demanding real value creation.
  • 2. Macroeconomic trends and interest rates significantly influence crypto dynamics, with stablecoins set to benefit from yield discrepancies.
  • 3. Regulatory clarity is essential for the industry's future, with active engagement needed to ensure favorable legislation.
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March 14, 2025

Why Is This Cycle Different? | Weekly Roundup

Empire

Crypto

Key Takeaways:

  • 1. Institutional interest in crypto is growing, focusing on stablecoins and Bitcoin as digital gold, despite current market volatility.
  • 2. Meme coins, while speculative, are essential for testing blockchain infrastructure and driving short-term market activity.
  • 3. Regulatory clarity is crucial for institutional adoption, with major financial institutions quietly expanding their crypto capabilities.
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March 14, 2025

CZ enters TAO arena, Kaito x Bittensor, exploits & more | TAO Talk

blocmates.

Crypto

Key Takeaways:

  • 1. CZ's investment in Tensorplex underscores the importance of influential backers in driving subnet success and innovation.
  • 2. The subnet 73 exploit highlights the need for robust security measures and transparent management practices in the Bittensor ecosystem.
  • 3. Kaito's integration with Bittensor demonstrates the potential for subnets to solve niche problems and enhance existing products.
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