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AI Podcasts

December 11, 2025

No Priors Ep. 143 | With ElevenLabs Co-Founder Mati Staniszewski

No Priors: AI, Machine Learning, Tech, & Startups

AI
Key Takeaways:
  1. Strategic Shift: The future of human-computer interaction is voice-first, moving from static content to dynamic, personalized, and agentic experiences.
  2. Builder/Investor Note: Defensibility in AI is increasingly found in deep product layers, specialized architectural breakthroughs (especially in audio), and robust ecosystems, not just raw model scale.
  3. The "So What?": Over the next 6-12 months, expect to see significant advancements in proactive AI agents, immersive media, and personalized education, with voice as the core interface.
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December 10, 2025

The Unicorn Founder Who Delegated Everything.

a16z

AI
Key Takeaways:
  1. The AI-Delegation Revolution is Here: Start experimenting with AI tools like ChatGPT for delegation now. The future involves proactive machine assistants deeply integrated into your workflow.
  2. Builders & Investors: Focus on "How to Delegate": The biggest constraint isn't finding assistants, but teaching clients how to delegate effectively. Tools and services that educate delegators will win.
  3. Reclaim Your Ambition: By offloading the mundane, you free up mental bandwidth to think bigger, pursue more ambitious goals, and ultimately, control your most valuable asset: time.
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December 12, 2025

AI Eats the World: Benedict Evans on the Next Platform Shift

a16z

AI
Key Takeaways:
  1. Strategic Implication: The AI bubble is inevitable. Focus on defensible positions: deep product integration, proprietary data, and distribution, rather than just raw model performance.
  2. Builder/Investor Note: The opportunity lies in productizing AI for specific "jobs to be done" within niche industries, creating intuitive UIs, and building in validation, not just building another foundational model.
  3. The "So What?": We're about to figure out the true "job to be done" for many industries. AI will unbundle existing businesses by exposing their hidden inefficiencies or non-obvious defensibilities.
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December 13, 2025

The Mathematical Foundations of Intelligence [Professor Yi Ma]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Embrace Parsimony and Self-Consistency: Adopt these principles as guiding forces in AI design. Build models that not only compress data efficiently but also maintain a high degree of self-consistency to ensure accurate and reliable world models.
  2. Focus on Abstraction, Not Just Memorization: Prioritize developing systems that can abstract knowledge beyond mere memorization. Move beyond surface-level compression and aim for models that can discover and reason about the underlying principles of the world.
  3. Understand and Reproduce the Brain’s Mechanisms: Focus on understanding and reproducing the mechanisms in the human brain that enable deductive reasoning, logical thinking, and the creation of new scientific theories to truly push AI to the next level.
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December 10, 2025

Nav Kumar: Trishool, AI Alignment, Subnet 23, Mechanistic Interpretability, Rogue LLMs | Ep. 75

Ventura Labs

AI
Key Takeaways:
  1. **Prioritize AI Safety Research:** Invest aggressively in understanding and mitigating AI risks to safeguard humanity against potential rogue LLMs.
  2. **Support Decentralized AI Alignment:** Champion decentralized platforms like Bit Tensor and initiatives like Trishool that promote open and transparent AI alignment research.
  3. **Embrace Mechanistic Interpretability:** Drive the development of tools that enable us to understand and control the internal workings of AI models, ensuring alignment with human values.
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December 10, 2025

Everyone Needs an Assistant. Here’s Why.

a16z

AI
Key Takeaways:
  1. Embrace Delegation as a Foundational Skill: Whether you leverage AI or human support, mastering delegation is paramount for unlocking personal and professional potential.
  2. Prioritize Time Ownership: Recognize time as your most valuable asset and design your life and calendar around your highest goals.
  3. Start Small, Scale Intentionally: Begin with affordable AI tools and gradually incorporate human assistance as your budget and needs evolve, building trust and compounding leverage over time.
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December 8, 2025

Building The Chip That Could Unlock AGI | Naveen Rao

a16z

AI
Key Takeaways:
  1. **Embrace Analog:** Explore and invest in analog computing solutions to overcome the energy limitations of current digital AI systems.
  2. **Prioritize Causality:** Shift focus towards AI models that incorporate time and causality, potentially unlocking more advanced and human-like intelligence.
  3. **Support Hardware Innovation:** Invest in and foster startups like Unconventional AI that are tackling fundamental challenges in AI hardware.
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December 8, 2025

Why AI Will Have To Run On Blockchains

The DCo Podcast

AI
Key Takeaways:
  1. Blockchain is essential for AI to ensure censorship resistance and uninterrupted accessibility.
  2. Trustworthy AI agents require on-chain governance to manage assets securely and transparently.
  3. AI agents can drastically accelerate blockchain adoption and optimize corporate processes.
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December 7, 2025

Tensor Logic "Unifies" AI Paradigms [Pedro Domingos]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Tensor Logic provides a unified framework for AI, bridging the gap between symbolic AI and deep learning, offering improved reasoning, transparency, and efficiency.
  2. The language addresses the limitations of current AI systems, enabling reliable deduction and facilitating structure learning through gradient descent, paving the way for more interpretable and controllable AI.
  3. Tensor Logic has the potential to advance AI education by providing a single language for teaching the entire gamut of AI. Its gradual adoption path allows developers to integrate it into existing workflows.
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Crypto Podcasts

June 30, 2025

Becoming a Crypto Millionaire with Sam Dogen

Bankless

Crypto
Key Takeaways:
  1. Stop Treating Crypto Like a Lotto Ticket. Apply fundamental personal finance rules. Your crypto portfolio needs a plan built on consistent saving and a clear understanding of your risk tolerance.
  2. Buy Your Slice of America. Don’t short the real estate market by renting long-term. Owning your primary residence is a forced savings and investment vehicle that historically outpaces inflation.
  3. Government Adoption is the Ultimate Bull Case. The most powerful tailwind for any asset class, including crypto, is government support. Regulatory clarity and institutional products (like ETFs) are signals that the asset is here to stay.
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June 30, 2025

Macro Updates, Industry Narratives & Big Tech Coming For Crypto | Permissionless IV Recap

Lightspeed

Crypto
Key Takeaways:
  1. **TradFi Is the New DeFi.** The most compelling crypto plays are now publicly traded companies acquiring Bitcoin. These “treasury companies” are the new tokens, using traditional stock markets for distribution that on-chain protocols can only dream of.
  2. **Brace for Big Tech's Invasion.** Robinhood and Stripe are coming for DeFi's profit margins. They are poised to dominate with superior UX and distribution, challenging the very premise of many decentralized applications.
  3. **Capital Follows Boomers, Not the Blockchain.** Don't expect government money printing to pump your altcoin bags. New capital is flowing into equities via money market funds. The only crypto assets benefiting are those packaged for TradFi consumption, like Bitcoin ETFs and treasury stocks.
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June 29, 2025

Building Web3 Businesses Comparison (2021 vs 2025) With Sandeep Nailwal

Empire

Crypto
Key Takeaways:
  1. Tokens Are a Liability, Not an Asset: A public token is a "net negative" that subjects founders to constant market ridicule. It's a 24/7 public referendum on your work, unlike the comparatively insulated world of traditional startups.
  2. The Era of Easy Capital Is Over: The days of raising $100M on a whitepaper are gone. Crypto fundraising now requires a level of traction and proof that is rapidly converging with the standards of traditional venture capital.
  3. Founder Liquidity Is No Longer a Guarantee: The promise of quick financial freedom for founders is fading. The extreme volatility of crypto markets means paper wealth can disappear before it ever becomes life-changing.
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June 27, 2025

Bell Curve x Empire: Prediction Markets, Crypto’s Magnificent 7, and Stablecoin Growth | Roundup

Bell Curve

Crypto
Key Takeaways:
  1. Business Models Over Memes: The new meta is clear: tokens must generate revenue. The most valuable assets will be those with defensible, on-chain business models, not just compelling narratives.
  2. The 4-Year Cycle is Dead: Forget halving-driven bull runs. We are in the first inning of a multi-year institutional adoption cycle, creating a sustained "global buy order" for legitimate crypto assets and related equities.
  3. Pick a Side (Token vs. Equity): The most critical question for any project is where value accrues. Investors must demand clarity on whether they are backing a decentralized network or a traditional company leveraging crypto rails.
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June 27, 2025

Bell Curve X Empire | Prediction Markets, Crypto’s Mag 7 & Stablecoin Growth | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Demand Cash Flow: The next crypto "Mag 7" will be defined by protocols with real, on-chain revenue and clear business models, not just speculative narratives.
  2. Bet on Yield: The predicted $3.7 trillion influx into stablecoins will disproportionately benefit yield-generating protocols, offering a prime opportunity as they re-rate to reflect their cash-generating power.
  3. The 4-Year Cycle is Dead: Forget the halving. Institutional capital entering via ETFs and public equities is transforming crypto into a multi-year bull market, fueled by a slow, steady global "T-WAP" of capital.
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June 27, 2025

Is Crypto’s Next Meta About to Make Markets Explode?

Bankless

Crypto
Key Takeaways
  1. The IPO Pipeline is Live: Circle's 10x IPO created a clear playbook. Watch private crypto leaders like Kraken and Fireblocks. Their public listings will be a crucial bellwether for the industry's mainstream acceptance.
  2. Watch Bitcoin Dominance, Not the Noise: A high and rising Bitcoin dominance is a coiled spring. When it finally breaks, it will likely break fast, signaling the true, explosive start of the next altcoin season.
  3. Crypto is Now a Political Asset: A directive ordering Fannie Mae and Freddie Mac to prepare for crypto-backed mortgages shows that digital assets have officially entered the political arena. This top-down push for legitimacy is a powerful tailwind, even if bottom-up bank adoption lags.
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