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AI Podcasts

September 10, 2025

Karl Friston - Why Intelligence Can't Get Too Large (Goldilocks principle)

Machine Learning Street Talk

AI
Key Takeaways:
  1. Intelligence Has a Size Limit: Forget galaxy-spanning superintelligences. The physics of self-organizing systems suggest intelligence thrives at a specific scale, unable to exist when systems become too large or too small.
  2. True Agency is Self-Inference: The crucial leap to higher intelligence is not just modeling the world, but modeling yourself as a cause within it. This recursive "strange loop" is the foundation of planning and agentic behavior.
  3. Hardware is the Software: Consciousness is not an algorithm you can run on any machine. It likely requires a specific physical substrate where memory and processing are unified, making the body and brain inseparable from the mind.
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September 10, 2025

Chris Dixon on How to Build Networks, Movements, and AI-Native Products

a16z

AI
Key Takeaways:
  1. **Ride the Wave, Don't Fight It.** Exponential forces like Moore's Law and network effects will overwhelm any product tactic. Your first job is to identify the fundamental technological or social current you're riding.
  2. **Build a Tool, Then a Network.** Defensibility in consumer tech often comes from network effects, but you can’t start there. Solve a user’s problem in single-player mode first to build the critical mass needed for an unbeatable network.
  3. **Explore the Fringe.** The future is being prototyped in niche subreddits and hobbyist communities. To find the next big thing, look for small groups of hyper-enthusiastic people working on things that seem like toys today.
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September 9, 2025

Mark Cuban on the NBA, Cost Plus Drugs, and How to Fix Politics

a16z

AI
Key Takeaways:
  1. Find the "Death War." Cuban's biggest wins come from identifying industries where competitors are forced to spend billions to survive (like AI today or streaming media rights a decade ago). These moments create massive opportunities for suppliers and disruptors.
  2. Sell a Better Life, Not an Ideology. Whether in politics or business, success comes from solving people’s immediate, tangible problems. Abstract goals and ideological purity don't sell.
  3. The Real Moat is Domain Expertise + AI. The next generation of billion-dollar companies will be built by founders who can apply AI to specific, overlooked business processes, creating hyper-efficient, customized SaaS solutions.
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September 8, 2025

The Little Tech Agenda for AI

a16z

AI
Key Takeaways:
  1. Stop Regulating Ghosts. Policy should target concrete, illegal uses of AI under existing laws, not hypothetical future harms that require licensing regimes and kill startups before they can compete.
  2. Compliance is a Competitive Moat. Regulations designed for trillion-dollar companies are a death sentence for startups. A 50-state patchwork of rules would be the final nail in the coffin for a competitive AI ecosystem.
  3. Innovation Needs a Political War Chest. The pro-innovation camp has been outmaneuvered by well-organized "safetyism" advocates. Building political gravity through organized efforts like PACs is now essential to ensure America wins the AI race.
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September 5, 2025

Shakeel Hussein: Ridges Subnet 62, AI Agents Coding, Alpha to Equity, Future of Software | Ep. 61

Ventura Labs

AI
Key Takeaways:
  1. **The Agent is the Moat.** Ridges’ success with cheaper models demonstrates that the true differentiator in AI coding is the agent architecture, not just the underlying LLM. This focus on efficiency creates a sustainable business model where competitors burn cash.
  2. **Alpha-to-Equity Creates a Capital Bridge.** This model directly ties the token's value to profit-sharing equity, creating an arbitrage loop for crypto and traditional funds. It offers a powerful alternative to typical tokenomics by capturing the value of the underlying business.
  3. **The Future of Software is Supervisory.** The ultimate goal is not just a better coding autocomplete, but a tool that elevates developers and product managers to supervisors of AI engineering teams, fundamentally changing how software is created.
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September 4, 2025

The Stock Market Is The Economy Now

Forward Guidance

AI
Key Takeaways:
  1. The Market is the Economy. The old wall between Wall Street and Main Street has crumbled. The high degree of financialization means they are now a single, symbiotic entity.
  2. Your Portfolio is a Utility. The stock market is becoming a public utility for distributing national wealth, with ownership becoming nearly universal. This trend is set to accelerate.
  3. Capital is the New Labor. This system provides the foundation for an AI economy by creating a mechanism to pay people from capital returns, solving the problem of mass unemployment before it begins.
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September 4, 2025

The Day AI Solves My Puzzles Is The Day I Worry (Prof. Cristopher Moore)

Machine Learning Street Talk

AI
Key Takeaways:
  1. **Stop Confusing Hardness with Reality.** Theoretical computer science focuses on worst-case scenarios. Real-world success hinges on exploiting messy, latent structure that we can’t even formally define yet.
  2. **Intelligence is Tool-Making.** Humans aren't just powerful processors; we're tool-users who extend our cognitive workspace. AI will remain limited until it can recognize its own limitations and build the tools it needs to overcome them.
  3. **Demand Transparency Over Explainability.** For high-stakes decisions like criminal justice or medical diagnoses, proprietary black boxes are unacceptable. The right to confront your accuser extends to the algorithms that judge you.
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September 2, 2025

COVENANT :: The Holy Grail of Decentralized AI Training on Bittensor SN3 +SN39 Basilica +SN81 Grail

The Opentensor Foundation | Bittensor TAO

AI
Key Takeaways:
  1. Decentralized Training is Unlocked. The SparseLoCo optimizer makes training massive (70B+ parameter) models over the internet practical. This is Bittensor’s direct answer to the centralized AI training monopoly.
  2. The Future is Value-Added Compute. Raw decentralized compute is a commodity game. Covenant’s strategy with Basilica is to win by building unique, high-margin services on top, like verifiable inference and hardware efficiency amplification.
  3. The Full Stack is the Moat. By integrating pre-training (Templar), intelligent compute (Basilica), and post-training (Grail), Covenant is building a flywheel. This synergy creates an end-to-end pipeline that is more than the sum of its parts.
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September 2, 2025

Substack Cofounder on AI Slop Content & the Decline of Social Media

a16z

AI
Key Takeaways:
  1. **The Media War is Attention vs. Intention.** The future isn't about more content; it's a battle between algorithmically-generated "slop" designed to hijack your attention and curated culture that serves your long-term interests.
  2. **True Platform Power is Granting Freedom.** Substack's most defensible moat is counterintuitive: giving creators the power to leave. This forces the platform to innovate and earn its keep, fostering genuine loyalty over lock-in.
  3. **Creators Are the New Founders.** The unbundling of talent from media institutions mirrors VC's impact on tech. Independent creators are becoming "ambitious media founders," building new ventures on platforms that align value creation with value capture.
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Crypto Podcasts

April 10, 2025

Can Blockchain Fix AI's "IP Problem"? With Story Protocol co-founder Jason Zhao

The People's AI

Crypto
Key Takeaways:
  1. Fix IP's Plumbing: Today's IP system is archaic; Story Protocol leverages blockchain for a transparent, programmable, global alternative.
  2. Monetize AI Training: Instead of fighting AI, creators can use Story to set terms and get paid for allowing their IP to be used in AI training or outputs.
  3. Tokenize Everything: IP is a $61T+ asset class (songs, data, brands); protocols like Story unlock its value through tokenization (IPRWAs) and new licensing models.
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April 9, 2025

Are We In A Bear Market? | Carlos Gonzalez Campo

Lightspeed

Crypto
Key Takeaways:
  1. Fundamental Disconnect: Solana's network activity (DEX volume, stablecoins) is stronger now than when SOL last traded below $100, despite the recent price plunge.
  2. Diverging Narratives: Bitcoin is trading like non-sovereign money, reacting to macro news, while Solana's price is more closely tied to its Layer 1 competition with Ethereum.
  3. Leverage Alert: Near-record high Solana open interest (in SOL terms) indicates significant leverage, suggesting amplified volatility potential ahead.
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April 9, 2025

Trump Is “Kitchen Sinking” The US Economy | Darius Dale

Forward Guidance

Crypto
Key Takeaways:
  1. Expect Pain Before Gain: The transition requires near-term economic disruption and market volatility ("go down to go up") before potential long-term benefits materialize. Markets haven't fully priced this in.
  2. Fed Will Be Forced to Act: Ignore Fed rhetoric; expect QE driven by financial stability needs and the debt cycle, regardless of stated intentions about rate levels. Structural inflation near 3% makes the 2% target a source of policy error.
  3. Ditch Long Bonds, Embrace Systems: Structural inflation and fiscal risks make long-term bonds unattractive. Navigate the volatile "Fourth Turning" environment with systematic, rules-based strategies dynamically allocating across assets like stocks, gold, and Bitcoin, prioritizing risk management over prediction.
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April 8, 2025

Why Is Trump Nuking Markets? | Felix Jauvin

1000x Podcast

Crypto
Key Takeaways:
  1. Buy the Dip (Carefully): In times of extreme fear (VIX 50+, Equities -20%), layer into positions incrementally; don't try to perfectly time the bottom or get trapped holding losers.
  2. Bitcoin's Moment?: Deglobalization, capital controls, and foreign stimulus could provide short-to-medium term tailwinds for Bitcoin, potentially decoupling it from traditional risk assets.
  3. Inflation Is Likely Toast: Barring a hot war, the economic slowdown from tariffs likely outweighs direct price impacts, paving the way for eventual Fed easing, even if Powell plays coy for now.
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April 8, 2025

The State Of Solana With Carlos Gonzalez Campo

Lightspeed

Crypto
Key Takeaways:
  1. Apps Outearn the Chain: Solana apps are generating nearly twice the revenue ($1.84) per dollar compared to the network itself, proving strong economic viability on the platform.
  2. Fundamentals Over Price: Despite SOL's price drop, core network health indicators like stablecoin supply and DEX activity remain robust, suggesting the sell-off may be detached from on-chain reality.
  3. L1 Scaling is Priority: Solana is doubling down on enhancing the L1 directly via upgrades (like TPU feedback) and app-level innovation (off-chain elements), rejecting Ethereum's L2 path to keep liquidity unified.
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April 8, 2025

Grifters, Meme Coins & the Solana Comeback

The Rollup

Crypto
Key Takeaways:
  1. Grifters Follow the Heat: Speculative actors migrate to blockchains with the highest activity and potential returns, currently favouring Solana's meme coin ecosystem.
  2. Meme Coins Drive Cycles: Love them or hate them, meme coins are a powerful catalyst for user activity, price appreciation, and ecosystem attention, replicating patterns seen in Ethereum's growth.
  3. Underdog Narratives Fuel Growth: Facing adversity can forge strong, defiant communities (like Solana post-FTX) that focus inward and drive significant comebacks, echoing Ethereum's own path to dominance.
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