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AI Podcasts

December 20, 2025

Are AI Benchmarks Telling The Full Story? [SPONSORED]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Strategic Shift: The market will increasingly demand AI models evaluated on human-centric metrics, not just technical benchmarks. Companies prioritizing user experience and safety will gain a competitive edge.
  2. Builder/Investor Note: Investigate companies developing or utilizing advanced, demographically representative human evaluation frameworks. These are crucial for building defensible, user-aligned AI products.
  3. The "So What?": Over the next 6-12 months, expect a growing focus on AI safety, ethical alignment, and nuanced human preference data. The "Wild West" of AI evaluation is ending, paving the way for more robust, trustworthy systems.
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December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Strategic Implication: The next frontier in AI is agentic, and progress hinges on fundamental pre-training innovation, not just post-training optimizations.
  2. Builder/Investor Note: Focus on teams with deep experience in scaling and debugging large models, as this is a high-capital, high-risk endeavor. Builders should prioritize developing new benchmarks for agentic capabilities.
  3. The "So What?": The industry needs to move beyond next-token prediction and static benchmarks to unlock truly capable, self-correcting AI agents in the next 6-12 months.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Shift in AI Development: The focus moves from syntax-aware code generation to execution-aware reasoning, enabling more robust and intelligent code agents.
  2. Builder/Investor Note: Prioritize tools and platforms that support explicit execution modeling and highly asynchronous, high-throughput RL training for agentic systems.
  3. The "So What?": AI that can simulate complex systems internally will drastically reduce development and testing costs, accelerating innovation in software and distributed systems over the next 6-12 months.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Strategic Shift: AI-driven kernel generation is not replacing human genius but augmenting it, allowing experts to focus on novel breakthroughs while AI automates the application of known optimizations across a complex hardware landscape.
  2. Builder/Investor Note: Focus on robust validation and hardware-in-the-loop systems. Claims of "AI inventing new algorithms" in this domain are premature. The real value is in automating the "bag of tricks" for heterogeneous compute.
  3. The "So What?": This technology is critical for scaling agentic AI workloads. Expect significant investment in tools that abstract hardware complexity and enable efficient, automated optimization, driving down the cost of AI inference in the next 6-12 months.
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December 18, 2025

AI Consulting in Practice – NLW, Super ai

AI Engineer

AI
Key Takeaways:
  1. The Agent Economy is Here: Enterprises are moving past pilots with AI agents. Builders should focus on orchestration layers and human-agent interaction design.
  2. ROI Measurement is the Next Frontier: Investors should look for solutions that help organizations accurately track and attribute AI value beyond traditional metrics.
  3. Strategic AI, Not Spot Solutions: The biggest wins come from systematic, cross-organizational AI strategies that target new capabilities and revenue growth, not just incremental time savings.
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December 18, 2025

How to build an AI native company (even if your company is 50 years old) – Dan Shipper, Every

AI Engineer

AI
Key Takeaways:
  1. The 100% AI adoption threshold is a step-function change, not incremental. Companies that commit fully will outpace those with partial integration.
  2. Builders should prioritize "compounding engineering" by codifying knowledge into reusable prompts. This builds an organizational memory that accelerates future development exponentially.
  3. Re-evaluate team structures and roles. Single engineers can own complex products, and even technical managers can contribute code, shifting how organizations operate.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. Effective crime reduction requires a shift from reactive punishment to proactive, intelligence-driven deterrence, making it highly probable for criminals to be caught.
  2. The market for AI-powered public safety technology, particularly solutions that integrate data for precision and accountability, presents a significant opportunity. Public-private partnerships are a key funding mechanism.
  3. Over the next 6-12 months, expect to see more cities adopt advanced surveillance and AI tools, driven by private funding, as they seek to improve safety and address staffing shortages without resorting to ineffective, broad-stroke policies.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade will be defined by who builds the core infrastructure for intelligence. This is where the most significant value and influence will accrue.
  2. Builder/Investor Note: Direct capital and talent towards foundational AI components—chips, models, and interoperable systems. Avoid the temptation to only build at the application layer.
  3. The So What?: The window for shaping the future of intelligence is now. Engage in the deepest, most complex challenges to secure a footprint in this new era.
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December 18, 2025

The EU and the not-so-simple macroeconomics of AI – Luis Garicano

Epoch AI

AI
Key Takeaways:
  1. Strategic Implication: The global AI race is a zero-sum game for foundational models. Europe's best strategy is a "smart second mover" approach, focusing on the implementation layer by ensuring interoperability and data portability.
  2. Builder/Investor Note: Invest in AI that achieves true autonomy and enhances expert productivity. Be wary of markets stifled by over-regulation, which can impede AI adoption and growth.
  3. The "So What?": Europe faces a critical juncture. Without embracing AI-driven growth, its demographic and debt problems will worsen, leading to higher interest rates without the corresponding economic expansion.
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Crypto Podcasts

August 4, 2025

Lightspeed Cross-Post: The State Of Solana With Carlos Gonzalez Campo

0xResearch

Crypto
Key Takeaways
  1. The Narrative Gap: Solana is shipping game-changing tech like Jito’s BAM, but it’s losing market momentum to Ethereum’s simpler, more digestible "digital treasury" narrative. This highlights a critical disconnect between engineering reality and market perception.
  2. BAM is an Ecosystem Reset: Jito’s BAM isn’t a simple patch; it's a foundational redesign of Solana's value pipeline. By internalizing MEV and enabling custom sequencing, it directly challenges the business model of SVM appchains and unlocks a new design space for DeFi on the L1.
  3. Decentralization is a Means, Not an End: The push for higher block limits signals a pragmatic shift. The ecosystem is increasingly willing to trade some degree of validator decentralization for the massive performance gains needed to onboard real-world finance, prioritizing the network's ultimate utility over ideological purity.
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August 4, 2025

The Bull Case For GLXY

Empire

Crypto
Key Takeaways:
  1. A Sum-of-the-Parts Discount: The market is failing to properly value Galaxy’s three distinct segments. The existing data center deal with CoreWeave alone is arguably worth more than the current stock price, meaning investors get the robust crypto business and a multi-billion dollar balance sheet for free.
  2. Unmatched Credibility in AI Pivot: Galaxy’s multi-billion dollar balance sheet is its trump card. It provides the financial muscle and credibility to secure financing and execute massive data center projects, a feat cash-burning Bitcoin miners can only talk about.
  3. An Execution-Driven Rocket Ship: The current valuation offers a significant margin of safety. If management successfully executes the full buildout of Helios and secures new tenants for its massive power pipeline, the upside is astronomical.
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August 1, 2025

Inside Crypto’s Credit Revival With Sid Powell | Roundup

Bell Curve

Crypto
Key Takeaways
  1. The US is Back in the Game: The regulatory climate has shifted from a headwind to a tailwind. The new clarity allows builders to focus on product, not legal acrobatics, and gives institutions the green light to engage.
  2. Leverage is Transparent, Not Gone: The system is deleveraged, but more importantly, its risk profile has improved dramatically. Leverage now lives in safer, productized, and on-chain formats built on verifiable custody rather than handshake deals.
  3. Bitcoin is Becoming Core Collateral: Look beyond Bitcoin as just "digital gold." Its true institutional power is emerging as a pristine collateral asset, set to anchor a multi-hundred-billion-dollar lending market packaged for TradFi consumption.
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August 1, 2025

SEC Announces "Project Crypto." This Changes Everything.

Bankless

Crypto
Key Takeaways:
  1. The On-Chain Mandate is Here. The SEC is no longer an obstacle but a proponent of moving U.S. capital markets onto blockchains. This signals a green light for builders and investors focused on tokenization and on-chain financial infrastructure.
  2. The "Pretend" Game is Over. With the SEC lead declaring "most tokens are not securities," the industry can move past the convoluted narratives used to avoid regulatory scrutiny. Projects can now be more direct about value accrual and business models.
  3. The Roman Storm Verdict is Crypto's Next Big Catalyst. The outcome of this trial will have profound implications. An acquittal would be a massive win for open-source developers and privacy, while a conviction could set a chilling precedent for years to come.
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July 30, 2025

How The U.S. Controls The Global Economy

Bankless

Crypto
Key Takeaways:
  1. Crypto Is America's Counter-Offensive. The U.S. is betting on privately-issued, regulated stablecoins—not a government-backed digital dollar—to maintain its edge in global payments. This strategy mirrors how it co-opted the offshore Eurodollar market in the 1970s to expand the dollar’s influence.
  2. The Rise of Parallel Systems. The weaponization of the dollar is forcing countries like China to build their own financial infrastructure (e.g., the M-Bridge platform). This guarantees a future where nations have multiple payment networks to choose from, eroding the U.S.’s unique leverage.
  3. Sanctions Are Not a Free Lunch. While a powerful alternative to military conflict, economic sanctions must be used judiciously. Overusing them risks dulling their impact and ultimately dismantling the very system that grants the U.S. its power.
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July 30, 2025

Can ETH Outperform SOL In 2025?

Lightspeed

Crypto
Key Takeaways:
  1. ETH's Narrative Is Its Near-Term Weapon. ETH's strength lies in a story simple enough for a "dumb banker": massive market cap, 80%+ stablecoin dominance, and the perceived success of its L2s. This makes it an easier buy for TradFi, even if the value accrual thesis is murky.
  2. Solana Is Playing The Long Game. Solana is betting that superior tech will ultimately win. Its focus isn't on the current TradFi narrative but on building the infrastructure for future "internet capital markets," a strategy that requires patience.
  3. Stablecoin Liquidity Is a Vanity Metric. Billions in stablecoins on platforms like Aave don't automatically translate to productive economic activity. The primary use case remains on-chain speculation, challenging the idea that massive liquidity is an end in itself.
See full notes