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AI Podcasts

December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Pre-Training is the New Frontier: The next leap in AI capabilities, particularly for agentic systems, will come from fundamental advancements in pre-training, not just post-training tweaks.
  2. Builders & Investors: Focus on teams rethinking loss objectives, curating high-quality reasoning data, and developing dynamic benchmarks for agentic capabilities. Be wary of "agentic" claims that lack foundational pre-training innovation.
  3. The "So What?": Over the next 6-12 months, expect a push for new benchmarks and data strategies that explicitly train models for multi-step planning, long-form reasoning, and error recovery, moving beyond simple next-token prediction.
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December 16, 2025

What We Learned Deploying AI within Bloomberg’s Engineering Organization – Lei Zhang, Bloomberg

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: AI fundamentally changes the economics of software development. Organizations must re-evaluate what constitutes "high-quality" engineering and adapt their processes.
  2. Builder/Investor Note: Prioritize platforms that provide guardrails and guidance for AI tool usage, focusing on deterministic verification and robust testing. Uncontrolled AI deployment risks technical debt.
  3. The "So What?": The next 6-12 months will see a bifurcation: companies that strategically integrate AI into their engineering culture and platforms will gain significant efficiency, while those that don't will struggle with quality and adoption.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Workflow Automation is the New Frontier: The real value of AI in developer tools comes from orchestrating entire workflows, not just individual point solutions.
  2. Embed for Adoption: Tools must integrate seamlessly into existing workflows and IDEs (like Cursor) to achieve high usage.
  3. Support as a Code-Shipping Powerhouse: Empowering non-traditional roles with AI-driven code generation leverages their unique, real-time context, creating significant operational leverage.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Semantic Shift: The future of AI in code moves from text generation to deep semantic understanding and execution simulation.
  2. Builder Opportunity: Develop next-generation debugging tools and code agents that leverage internal simulation for faster, more efficient development cycles.
  3. Investor Focus: Prioritize models and platforms that demonstrate explicit execution modeling, as this capability will redefine software development and create new market leaders.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Infrastructure Shift: AI-driven kernel optimization addresses a critical bottleneck in scaling AI compute, enabling more efficient use of diverse hardware.
  2. Builder/Investor Note: Focus on solutions with robust, hardware-verified performance metrics and a clear human-in-the-loop strategy. AI is a powerful tool for automating optimization, not a magic bullet for novel algorithmic breakthroughs.
  3. The "So What?": This technology frees expert engineers from tedious optimization, allowing them to focus on higher-level research and truly innovative algorithmic design, accelerating the pace of AI development in the next 6-12 months.
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December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The era of "free money" inflated the number of perceived compounders; a return to positive real rates demands a sharper focus on businesses demonstrating genuine financial discipline and competitive advantage.
  2. Builder/Investor Note: Seek out "Act 2" entrepreneurs and companies that can leverage AI to transform existing physical or IP-based advantages, not just create new AI products. Be prepared to buy more when market sentiment turns negative on strong businesses.
  3. The "So What?": The next 6-12 months will differentiate companies that merely adopt AI from those that strategically integrate it to build durable, uncatchable cost and distribution advantages.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. The Future of Policing is Intelligent: Integrating AI, drones, and smart cameras creates a precise, accountable, and safer policing model for both officers and communities.
  2. Invest in the "How": Builders and investors should focus on technologies that enhance certainty of capture, streamline judicial processes, and support public-private partnerships to modernize urban safety infrastructure.
  3. Safety Fuels Mobility: Eliminating crime is not just about law enforcement; it's about restoring the fundamental safety required for economic mobility and a functional society.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade's value will accrue to those building foundational AI infrastructure and the "invisible layers" that connect intelligent systems.
  2. Builder/Investor Note: Focus capital and talent on core AI models, specialized domain intelligence, and the underlying computational fabric. Superficial applications risk rapid commoditization.
  3. The So What?: This is the defining period for the architecture of global intelligence. Participation now determines future influence and relevance.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Shift: AI security must move beyond superficial guardrails to a full-stack, offensive red-teaming approach that accounts for the expanding attack surface of AI agents and their tool access.
  2. Builder/Investor Note: Builders should prioritize integrating offensive security early in development. Investors should be wary of "security theater" and favor solutions that embrace open-source collaboration and address the entire AI application stack.
  3. The "So What?": The accelerating pace of AI development means static security solutions will quickly become obsolete. Proactive, community-driven, and full-stack security research is essential for navigating the next 6-12 months of AI evolution.
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Crypto Podcasts

May 19, 2025

The Genius Behind the Biggest Crypto Exchange in the Sonic Ecosystem

blocmates.

Crypto
Key Takeaways:
  1. Performance is Paramount: Sonic's best-in-class EVM performance is a non-negotiable foundation for ambitious DeFi protocols.
  2. Organic Traction Trumps Hype: Sonic's user-driven ecosystem is cultivating genuine DeFi engagement and sustainable innovation.
  3. AI Will Onboard the Masses: Natural language AI interfaces are set to revolutionize crypto accessibility, making it usable for everyone.
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May 19, 2025

Arthur Hayes: Money Printing & The Crypto Bet

Bankless

Crypto
Key Takeaways:
  1. Brace for Capital Controls: The US is likely to implement capital controls over politically unpalatable tariffs to rebalance its economy, fundamentally changing global capital flows.
  2. Money Printing is Non-Negotiable: Regardless of political rhetoric, the US will print money to manage the fallout from capital flight and fund government spending, massively benefiting hard assets.
  3. Bitcoin & Gold are Your Life Rafts: In an era of devaluing fiat and financial repression, Bitcoin and gold are critical for wealth preservation and growth. Ditch long-term bonds.
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May 19, 2025

Logan Allen: Nockchain's Global Competition for Useful ZK Proof of Work Miners Kicks Off

Delphi Digital

Crypto
Key Takeaways:
  1. ZKPoW is a Novel Force: Nockchain's ZK Proof of Work directly builds valuable ZK proving capacity, turning mining into a productive, network-enhancing activity.
  2. Hardware Revolution Looms: The mining competition will drive innovation in ZK-specific hardware (FPGAs, ASICs for polynomial math), creating a new hardware market distinct from Bitcoin's.
  3. Intent-Driven Future: Nockchain's architecture points towards a future of composable "micro-apps" and verifiable services, where on-chain logic focuses on proof verification, potentially enabling new decentralized AI/ML applications and "computational commodities."
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May 18, 2025

Weimar America: The Inflation Spiral Has Begun

Forward Guidance

Crypto
Key Takeaways:
  1. **Fiscal Dominance is Here:** Government spending, not just Fed policy, is the primary driver of the current inflationary pressures and will likely lead to an 8% GDP deficit.
  2. **Prepare for Intervention:** Expect capital controls (like remittance taxes) and yield curve control as governments grapple with the consequences of their spending.
  3. **Store-of-Value is King:** In an environment where traditional savings (e.g., 4% on bonds) can't match 15% inflation in essential costs, assets like tech stocks and Bitcoin become non-negotiable for wealth preservation.
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May 17, 2025

The Fiscal Spiral Has No Off Switch | Weekly Roundup

Forward Guidance

Crypto
Key Takeaways:
  1. Fiscal Doom Loop: The US is locked in a fiscal spiral of growing deficits and debt that it seems unwilling or unable to escape, making dollar debasement a significant long-term risk.
  2. Macro is King: Geopolitical trends, capital flows, and policy decisions (like buybacks and potential yield curve control) are now more critical drivers of asset prices than individual company fundamentals.
  3. Bitcoin's Ascent: In a world of "Ponzi schemes," Bitcoin stands out as a rational hedge and potentially the "generational trade" against failing monetary and fiscal policies.
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May 16, 2025

The Next Phase of the Bull Market | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. **Memecoin Rebound Signals Risk-On:** The sharp recovery in memecoins highlights the market's speculative appetite; treat them as high-octane, ecosystem-specific bets.
  2. **Strategic M&A is Reshaping Access:** Companies are buying their way into regulated markets and building out institutional-grade services, with "Crypto as a Service" set to grow.
  3. **Institutional Rails Getting Stronger:** Coinbase’s S&P 500 debut and EToro’s IPO are landmark events, cementing crypto's place in mainstream finance and improving market transparency.
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