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AI Podcasts

November 17, 2025

Hash Rate - Ep 145 - TAO Subnets Templar (3), Basilica (39), Grail (81)

Hash Rate pod - Bittensor $TAO & Subnets

AI
Key Takeaways:
  1. **A New Market is Born:** Templar isn't just cheaper; it enables something that was previously impossible for 99% of the world. Democratizing pre-training means anyone can build a truly custom, sovereign AI.
  2. **Productization is Underway:** Covenant is no longer just a research project. With enterprise sales in motion, the focus is now on revenue. The team has committed that 100% of fees from custom training will be used to buy back its tokens.
  3. **Economics are Being Rewritten:** Basilica’s incentive mechanism is a direct critique of unsustainable models on other compute subnets. Its focus on profitability and positive TAO flow sets a new standard for economic design on Bittensor.
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November 17, 2025

Bryan Johnson: Don’t Die, Beating Entropy, AI Alignment & The Two-Species Future

Bankless

AI
Key Takeaways:
  1. AI Forces a Moral Reboot. The emergence of superintelligence renders our current societal goals dangerously obsolete. Survival must become the new prime directive.
  2. Existence is a Team Sport. The "Don't Die" philosophy is a collective mission ("we don't die") to ensure species-wide survival, not a selfish quest for individual immortality.
  3. Prepare for the Biological Sandbox. Humanity is moving from manipulating physical atoms and digital bits to programming our own biology—a frontier with both unimaginable potential and catastrophic risk.
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November 17, 2025

Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering

a16z

AI
Key Takeaways:
  1. Stop Trying to “Steer” AGI. The control paradigm is a dead end. The goal isn’t a more obedient tool; it’s a trustworthy teammate. We must shift from engineering control to cultivating care.
  2. Alignment is a Process, Not a Product. True alignment isn't a fixed set of rules. It’s a dynamic process of moral learning, akin to raising a child. AIs that only follow rules are brittle and dangerous.
  3. Build for Cooperation, Not Command. The technical path forward involves training AIs in rich, multi-agent environments where they must learn cooperation and theory of mind—the foundational skills for becoming a good member of a group.
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November 16, 2025

Rawson Haverty presents "US & China AI: Lessons from Across the Pacific" | dAGI Summit 2025

Delphi Digital

AI
Key Takeaways:
  1. US Leads in Capital-Intensive Frontier AI; China Excels at Industrial Diffusion. The US leverages deep capital markets for its massive compute buildout and AGI research, while China uses state direction to embed AI into its vast industrial base via open-source models and hardware.
  2. Market Structure Dictates AI Strategy. The US "efficient oligopoly" model prioritizes global dominance and profit reinvestment by a few players. China's "subjugated swarm" model creates intense domestic competition, driving down prices and accelerating adoption at the cost of profitability.
  3. Geopolitical Tension May Be a Necessary Stabilizer. The competition between the US's freedom-oriented, frontier-pushing approach and China's stability-focused, diffusion-driven model creates a complementary tension that could be essential for navigating the "narrow corridor" between AI-driven totalitarianism and uncontrollable chaos.
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November 13, 2025

How Will AI Change Gaming Development? (A Dev’s Take)

The DCo Podcast

AI
Key Takeaways:
  1. Development timelines are collapsing from months to days. AI allows developers to swap entire asset libraries or generate new game concepts at unprecedented speed, turning a two-month art project into a day's work.
  2. The lifespan of any single game is shrinking. Prepare for a world of disposable entertainment. As AI floods the market with content, the strategy will pivot from creating one long-lasting hit to deploying a rapid succession of engaging experiences.
  3. Games are the next evolution of the attention economy. Just as memes became a core tool for community-building around tokens, easily created games will be the next engine for capturing and directing user attention in a hyper-competitive digital world.
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November 11, 2025

AI Nerves, Crypto Realism, Privacy Coins, & Lessons From Trading

1000x Podcast

AI
Key Takeaways:
  1. Adopt a Stock Picker's Mentality. The crypto market is no longer a monolith where a rising tide lifts all boats. Focus on assets with real products, user growth, and cash flow, as the gap between winners and losers will only widen.
  2. Shorting is a Tactical Assault, Not a Siege. Don't "invest" in a short. The only viable short strategies are tactical, targeting specific events like VC unlocks or news-driven spikes. Otherwise, even "total scams" can 5x against you.
  3. Cultivate a Goldfish's Memory. The most critical trading skill is learning how to change your mind. Cut losing trades, forget the loss (but remember the lesson), and redeploy capital without emotional baggage. Stubbornness is a portfolio killer.
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November 11, 2025

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

a16z

AI
Key Takeaways:
  1. Word-of-mouth isn't a feature; it's the engine. Before spending a dime on marketing, obsess over the first 30 seconds of the user experience until people can't help but share it.
  2. Being different is better than being better. Don't build incrementally better slideware. Redefine the core primitives of your category, as Gamma did by moving beyond the 16x9 slide.
  3. Hire painfully slowly to protect your DNA. Resisting the temptation to scale headcount with user growth is a superpower. The goal isn't to hit a hiring target; it's to hire the best people.
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November 7, 2025

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

a16z

AI
Key Takeaways:
  1. AGI Is a Definitional Debate. Progress toward an AI that can replace a remote worker is happening fast. However, achieving "true" human-like learning efficiency may require an entirely new paradigm beyond scaling current LLMs.
  2. The New Creator Economy Is Code. AI is turning software development into a mainstream creative pursuit, empowering a new class of solo entrepreneurs who can build what previously required entire teams.
  3. Incumbents Learned Their Lesson. Unlike past tech shifts, today's giants are aggressively adopting AI, making it both a sustaining *and* disruptive force. The market is large enough for both incumbents and startups to create massive value.
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November 6, 2025

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

a16z

AI
Key Takeaways:
  1. Build the Tools, Not Just the House: CZI’s greatest leverage comes from creating open-source tools and datasets. By building the fundamental infrastructure, they empower the entire scientific community—from academic labs to startups—to accelerate discovery.
  2. Data Is the New Microscope: The future of biology hinges on a tight feedback loop between generating novel, purpose-built datasets and training domain-specific AI models on them. This synergy is unlocking insights that were previously impossible.
  3. Virtual Biology Is the Next Frontier: Simulating biology computationally with "virtual cells" will become the new standard for research, enabling scientists to test riskier hypotheses faster and cheaper, dramatically compressing the timeline for major breakthroughs.
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Crypto Podcasts

August 31, 2025

Hash Rate - Ep 130 - What IS Bittensor -- Actually? The Latest Thinking

Hash Rate pod - Bitcoin, AI, DePIN, DeFi

Crypto
Key Takeaways:
  1. A New Economic Primitive: Bittensor is pioneering "Incentivism," a model that replaces traditional companies with a decentralized network of goals and globally competing workers, creating a system that is described as "capitalism squared.
  2. TAO is an Index on Innovation: The network is designed so all value accrues back to the base TAO token through staking mechanisms. Investing in TAO is effectively an index bet on the entire ecosystem’s innovation.
  3. An Unbeatable Cost Structure: The "Law of Subnet Stacking" enables exponential cost reductions, giving the Bittensor ecosystem a potentially insurmountable competitive advantage over centralized incumbents.
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August 30, 2025

Is Hyperliquid The Wild West? Has The Market Topped?! w/ Dim Selk

Steady Lads Podcast

Crypto
Key Takeaways:
  1. **The Market Is Cooked.** With momentum buyers exhausted and value buyers absent, the risk/reward on majors like BTC and ETH is heavily skewed to the downside. The party may not be over, but it's time to find the exit.
  2. **DEXs Are Not CEXs.** Decentralized perpetual exchanges like Hyperliquid offer unparalleled access but lack the circuit breakers and centralized oversight of a Binance. In these venues, you are the risk manager, and there is no sheriff coming to save you.
  3. **Beware OG Whales.** The market is still heavily influenced by a small number of early crypto holders operating with immense capital and unsophisticated "ape first, research later" strategies. Their unpredictable actions can and will create violent dislocations.
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August 29, 2025

ETH Hits New ATH! Powell Hints at Rate Cuts & BTC Whales Rotate to ETH

Bankless

Crypto
Key Takeaways:
  1. **The Fed's dovish turn is the primary market catalyst.** Powell's signals of impending rate cuts have injected massive optimism, driving ETH to a new all-time high and confirming that macro now dictates crypto's direction.
  2. **Capital is aggressively rotating from Bitcoin to Ether.** This classic cycle rotation, amplified by whale activity and trader expectations, is a self-fulfilling prophecy, positioning ETH as the next dominant asset to watch.
  3. **The Solana treasury narrative is the next frontier.** With the window closing for new Bitcoin and ETH treasury vehicles, a fierce competition is underway to establish the dominant, "Saylor-like" figurehead for Solana, creating a new focal point for institutional capital.
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August 29, 2025

NFTs As Top Signals

Empire

Crypto
Key Takeaways:
  1. **Track NFT Blue-Chips as a Signal.** The price action of collections like CryptoPunks acts as a potent gauge for the "wealth effect" and overall risk appetite within the crypto ecosystem. Their peaks often correlate with broader market tops.
  2. **Separate Collecting from Investing.** Frame high-end NFT acquisitions as an "expense" for art you genuinely love, not a financial investment. This strategy decouples your emotional well-being from market volatility.
  3. **Embrace Your Top-Signal Buys.** An expensive purchase at a market peak isn't just a loss; it's a powerful lesson in humility. Use it as a constant reminder that no one is immune to market psychology.
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August 27, 2025

How to Make it This Cycle w/ CryptoMessi

Taiki Maeda

Crypto
Key Takeaways:
  1. Ditch the Rotator Playbook. This isn't 2021. Stop chasing every pump. Success this cycle requires picking a few narratives, believing in them, and holding with conviction.
  2. Make On-Chain Money Real. Stablecoins encourage bad habits. Cash out profits to a real bank account to create a psychological barrier against recklessly aping your gains back into the market.
  3. Plan for Post-Win Depression. The dopamine crash after a massive score is inevitable. Resist the urge to chase that high; prioritize building sustainable, real-world income instead of buying status symbols.
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August 27, 2025

Trump’s Tariffs Could Stall Growth Before 2026 Surge | Alfonso Peccatiello

Forward Guidance

Crypto
Key Takeaways:
  1. A Politicized Fed is the Baseline. Assume the Federal Reserve will be pressured to cut rates to neutral (~3%) by 2026, creating an unusually loose policy backdrop relative to strong nominal growth.
  2. Mind the Fiscal Cliff, Then the Rocket Ship. Brace for a temporary growth slowdown as tariffs bite over the next few months, but prepare for a sharp re-acceleration in 2026 if and when new stimulus kicks in.
  3. Ditch Old Hedges, Buy Protest Assets. Your portfolio's traditional diversifiers (long bonds, USD) are broken. Shift allocation toward assets that benefit from inflation risk and high nominal growth: commodities, crypto, and undervalued international equities.
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