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AI Podcasts

February 3, 2026

Why The Laws of Startup Physics Have Changed | Ben Horowitz Interview

Invest Like The Best

AI
Key Takeaways:
  1. The Macro Shift: AI is collapsing the time horizon for technological deployment and market dominance, shifting the competitive advantage from pure innovation to a combination of innovation, capital, and rapid infrastructure deployment.
  2. The Tactical Edge: Invest in companies that are not just building AI, but are fundamentally rethinking existing industries with AI-first principles, recognizing that traditional software moats are eroding.
  3. The Bottom Line: The next 12-24 months will see AI's broad impact kick in, creating unprecedented opportunities for those who understand its new "laws of physics" and the critical role of policy in shaping its trajectory.
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February 4, 2026

Ozempic Won't Solve America's Obesity Problem

a16z

AI
Key Takeaways:
  1. The healthcare system is moving from reactive, acute care to proactive, preventative interventions, driven by the unsustainable costs of chronic disease and a growing understanding of environmental health.
  2. Build infrastructure that financially incentivizes lifestyle interventions, such as TrueMed's HSA/FSA payment rails for health-promoting products and services.
  3. The next decade will see hundreds of billions of dollars redirected towards preventative health. Companies that bridge the gap between lifestyle choices and healthcare financing will capture significant market share.
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February 3, 2026

SpaceX Engineer Explains America's Biggest Energy Mistake | Scott Nolan, CEO of General Matter

The Generalist

AI
Key Takeaways:
  1. The Macro Shift: Global energy demand, driven by AI, forces a strategic re-evaluation of nuclear power. This creates a window for nations to re-shore critical energy infrastructure, moving from reliance on adversaries to domestic, cost-competitive solutions.
  2. The Tactical Edge: Investigate companies addressing foundational supply chain gaps in critical industries like energy. Look for teams with a "first principles" engineering approach and a track record of commercializing hard tech.
  3. The Bottom Line: America's energy independence and its ability to power future technological growth, like AI, hinge on rebuilding domestic nuclear fuel enrichment. This is not just an industrial opportunity; it is a national security imperative.
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February 4, 2026

The Economic Singularity Will Make Today’s Economy Unrecognizable w/ Dr. Alexander Wissner-Gross

Milk Road AI

AI
Key Takeaways:
  1. The Macro Shift: AI-driven hyperdeflation is colliding with the technical reality of autonomous AI agents creating their own crypto-backed economies, threatening a decoupling from human fiat systems.
  2. The Tactical Edge: Investigate and build infrastructure that bridges human and AI economies, focusing on fiat-to-crypto rails that can accommodate agent-driven transactions to prevent a complete split.
  3. The Bottom Line: The next 5-10 years will see an unprecedented economic transformation. Understanding AI's deflationary power and the emerging AI agent economy is critical for navigating a world where traditional economic models may no longer apply.
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February 3, 2026

OpenClaw Makes AI Agents and CPUs Get Real

Semi Doped

AI
Key Takeaways:
  1. The time of practical AI agents is here, moving compute demand beyond pure GPU inference to a significant reliance on CPUs for coordination, data handling, and security.
  2. Evaluate your agent deployment strategy now, prioritizing sandboxed environments (VPS, dedicated local servers) and exploring cost-optimized model routing to manage API expenses.
  3. Prepare for a future where AI agents become integral to workflows, but recognize the hidden infrastructure costs and security implications, particularly the growing importance of CPU capacity and robust access controls.
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February 4, 2026

⚡️ Context graphs: AI’s trillion-dollar opportunity — Jaya Gupta, Ashu Garg, Foundation Capital

Latent Space

AI
Key Takeaways:
  1. The shift from "how" to "why" in AI agent capabilities creates a new, multi-trillion-dollar market for companies that can capture institutional decision logic.
  2. Invest in or build agentic systems that are in the "right path" of business processes, actively capturing decision traces from unstructured data.
  3. Hundreds of context graphs will be in production at scale within a year, defining a new "context graph stack." The winning companies will be those that master this flywheel, extracting value to accelerate automation and build deep, defensible moats.
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February 2, 2026

We Entered an Era Where No One Knows What Comes Next

Turing Post

AI
Key Takeaways:
  1. The shift from linear, bottleneck-driven technological progress to a multi-layered, interconnected advancement model in AI has rendered traditional forecasting obsolete, forcing a re-evaluation of what "singularity" truly represents.
  2. Prioritize adaptability: Invest in modular, composable AI infrastructure and tools that thrive in multi-layered, unpredictable environments, rather than betting on single-bottleneck solutions.
  3. The inability to narrate AI's future means traditional roadmaps are obsolete; success hinges on navigating simultaneous, interconnected advancements and embracing the emergent.
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February 3, 2026

Why The Laws of Startup Physics Have Changed | Ben Horowitz Interview

Invest Like The Best

AI
Key Takeaways:
  1. The era of infrastructure-heavy tech deployment is over; AI's internet-native nature means immediate, widespread application. This shifts the competitive advantage from capital-intensive builds to rapid iteration and data leverage.
  2. Invest in companies that are not just using AI, but are fundamentally rethinking their business models around AI's ability to collapse traditional cost structures and accelerate product development.
  3. AI is a force multiplier for both individual opportunity and national power. Understanding its immediate deployability and the new rules of company building is crucial for investors and builders aiming to lead in the next wave of innovation over the next 12-24 months.
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February 2, 2026

Ben Horowitz and David Solomon: The Sweetest Macro Spot in 40 Years

a16z

AI
Key Takeaways:
  1. Unprecedented fiscal and monetary stimulus, coupled with a deregulatory environment, creates a powerful tailwind for financial assets and tech, driving a capital investment super cycle.
  2. Investors should prioritize companies with proprietary data and GPU access, as these are the new moats in an AI-driven world where traditional software leads are eroding.
  3. The convergence of a stimulative macro environment and AI's disruptive force means capital will flow to those who can scale, innovate, and navigate complex policy landscapes, making strategic positioning now critical for future relevance.
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Crypto Podcasts

August 4, 2025

What To Own This Cycle?

1000x Podcast

Crypto
Key Takeaways:
  1. Own What Institutions Buy. This is not a crypto-native cycle. The winning strategy is to hold the assets institutions are buying: Bitcoin, Ethereum, and potentially Ripple as a speculative trade on its IPO.
  2. Trade Crypto Stocks Like Memes. Public companies like Galaxy are being driven by retail hype, not fundamentals. This creates high-volatility trading opportunities for those who can ride the narrative waves.
  3. Hold Your Conviction. The macro backdrop is incredibly bullish. Don't let healthy, short-term corrections driven by "amateur hour" traders shake you out of your positions before the real move happens.
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August 4, 2025

Lightspeed Cross-Post: The State Of Solana With Carlos Gonzalez Campo

0xResearch

Crypto
Key Takeaways
  1. The Narrative Gap: Solana is shipping game-changing tech like Jito’s BAM, but it’s losing market momentum to Ethereum’s simpler, more digestible "digital treasury" narrative. This highlights a critical disconnect between engineering reality and market perception.
  2. BAM is an Ecosystem Reset: Jito’s BAM isn’t a simple patch; it's a foundational redesign of Solana's value pipeline. By internalizing MEV and enabling custom sequencing, it directly challenges the business model of SVM appchains and unlocks a new design space for DeFi on the L1.
  3. Decentralization is a Means, Not an End: The push for higher block limits signals a pragmatic shift. The ecosystem is increasingly willing to trade some degree of validator decentralization for the massive performance gains needed to onboard real-world finance, prioritizing the network's ultimate utility over ideological purity.
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August 4, 2025

The Bull Case For GLXY

Empire

Crypto
Key Takeaways:
  1. A Sum-of-the-Parts Discount: The market is failing to properly value Galaxy’s three distinct segments. The existing data center deal with CoreWeave alone is arguably worth more than the current stock price, meaning investors get the robust crypto business and a multi-billion dollar balance sheet for free.
  2. Unmatched Credibility in AI Pivot: Galaxy’s multi-billion dollar balance sheet is its trump card. It provides the financial muscle and credibility to secure financing and execute massive data center projects, a feat cash-burning Bitcoin miners can only talk about.
  3. An Execution-Driven Rocket Ship: The current valuation offers a significant margin of safety. If management successfully executes the full buildout of Helios and secures new tenants for its massive power pipeline, the upside is astronomical.
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August 1, 2025

Inside Crypto’s Credit Revival With Sid Powell | Roundup

Bell Curve

Crypto
Key Takeaways
  1. The US is Back in the Game: The regulatory climate has shifted from a headwind to a tailwind. The new clarity allows builders to focus on product, not legal acrobatics, and gives institutions the green light to engage.
  2. Leverage is Transparent, Not Gone: The system is deleveraged, but more importantly, its risk profile has improved dramatically. Leverage now lives in safer, productized, and on-chain formats built on verifiable custody rather than handshake deals.
  3. Bitcoin is Becoming Core Collateral: Look beyond Bitcoin as just "digital gold." Its true institutional power is emerging as a pristine collateral asset, set to anchor a multi-hundred-billion-dollar lending market packaged for TradFi consumption.
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August 1, 2025

SEC Announces "Project Crypto." This Changes Everything.

Bankless

Crypto
Key Takeaways:
  1. The On-Chain Mandate is Here. The SEC is no longer an obstacle but a proponent of moving U.S. capital markets onto blockchains. This signals a green light for builders and investors focused on tokenization and on-chain financial infrastructure.
  2. The "Pretend" Game is Over. With the SEC lead declaring "most tokens are not securities," the industry can move past the convoluted narratives used to avoid regulatory scrutiny. Projects can now be more direct about value accrual and business models.
  3. The Roman Storm Verdict is Crypto's Next Big Catalyst. The outcome of this trial will have profound implications. An acquittal would be a massive win for open-source developers and privacy, while a conviction could set a chilling precedent for years to come.
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July 30, 2025

How The U.S. Controls The Global Economy

Bankless

Crypto
Key Takeaways:
  1. Crypto Is America's Counter-Offensive. The U.S. is betting on privately-issued, regulated stablecoins—not a government-backed digital dollar—to maintain its edge in global payments. This strategy mirrors how it co-opted the offshore Eurodollar market in the 1970s to expand the dollar’s influence.
  2. The Rise of Parallel Systems. The weaponization of the dollar is forcing countries like China to build their own financial infrastructure (e.g., the M-Bridge platform). This guarantees a future where nations have multiple payment networks to choose from, eroding the U.S.’s unique leverage.
  3. Sanctions Are Not a Free Lunch. While a powerful alternative to military conflict, economic sanctions must be used judiciously. Overusing them risks dulling their impact and ultimately dismantling the very system that grants the U.S. its power.
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