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AI Podcasts

December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Pre-Training is the New Frontier: The next leap in AI capabilities, particularly for agentic systems, will come from fundamental advancements in pre-training, not just post-training tweaks.
  2. Builders & Investors: Focus on teams rethinking loss objectives, curating high-quality reasoning data, and developing dynamic benchmarks for agentic capabilities. Be wary of "agentic" claims that lack foundational pre-training innovation.
  3. The "So What?": Over the next 6-12 months, expect a push for new benchmarks and data strategies that explicitly train models for multi-step planning, long-form reasoning, and error recovery, moving beyond simple next-token prediction.
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December 16, 2025

What We Learned Deploying AI within Bloomberg’s Engineering Organization – Lei Zhang, Bloomberg

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: AI fundamentally changes the economics of software development. Organizations must re-evaluate what constitutes "high-quality" engineering and adapt their processes.
  2. Builder/Investor Note: Prioritize platforms that provide guardrails and guidance for AI tool usage, focusing on deterministic verification and robust testing. Uncontrolled AI deployment risks technical debt.
  3. The "So What?": The next 6-12 months will see a bifurcation: companies that strategically integrate AI into their engineering culture and platforms will gain significant efficiency, while those that don't will struggle with quality and adoption.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Workflow Automation is the New Frontier: The real value of AI in developer tools comes from orchestrating entire workflows, not just individual point solutions.
  2. Embed for Adoption: Tools must integrate seamlessly into existing workflows and IDEs (like Cursor) to achieve high usage.
  3. Support as a Code-Shipping Powerhouse: Empowering non-traditional roles with AI-driven code generation leverages their unique, real-time context, creating significant operational leverage.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Semantic Shift: The future of AI in code moves from text generation to deep semantic understanding and execution simulation.
  2. Builder Opportunity: Develop next-generation debugging tools and code agents that leverage internal simulation for faster, more efficient development cycles.
  3. Investor Focus: Prioritize models and platforms that demonstrate explicit execution modeling, as this capability will redefine software development and create new market leaders.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Infrastructure Shift: AI-driven kernel optimization addresses a critical bottleneck in scaling AI compute, enabling more efficient use of diverse hardware.
  2. Builder/Investor Note: Focus on solutions with robust, hardware-verified performance metrics and a clear human-in-the-loop strategy. AI is a powerful tool for automating optimization, not a magic bullet for novel algorithmic breakthroughs.
  3. The "So What?": This technology frees expert engineers from tedious optimization, allowing them to focus on higher-level research and truly innovative algorithmic design, accelerating the pace of AI development in the next 6-12 months.
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December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The era of "free money" inflated the number of perceived compounders; a return to positive real rates demands a sharper focus on businesses demonstrating genuine financial discipline and competitive advantage.
  2. Builder/Investor Note: Seek out "Act 2" entrepreneurs and companies that can leverage AI to transform existing physical or IP-based advantages, not just create new AI products. Be prepared to buy more when market sentiment turns negative on strong businesses.
  3. The "So What?": The next 6-12 months will differentiate companies that merely adopt AI from those that strategically integrate it to build durable, uncatchable cost and distribution advantages.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. The Future of Policing is Intelligent: Integrating AI, drones, and smart cameras creates a precise, accountable, and safer policing model for both officers and communities.
  2. Invest in the "How": Builders and investors should focus on technologies that enhance certainty of capture, streamline judicial processes, and support public-private partnerships to modernize urban safety infrastructure.
  3. Safety Fuels Mobility: Eliminating crime is not just about law enforcement; it's about restoring the fundamental safety required for economic mobility and a functional society.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade's value will accrue to those building foundational AI infrastructure and the "invisible layers" that connect intelligent systems.
  2. Builder/Investor Note: Focus capital and talent on core AI models, specialized domain intelligence, and the underlying computational fabric. Superficial applications risk rapid commoditization.
  3. The So What?: This is the defining period for the architecture of global intelligence. Participation now determines future influence and relevance.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Shift: AI security must move beyond superficial guardrails to a full-stack, offensive red-teaming approach that accounts for the expanding attack surface of AI agents and their tool access.
  2. Builder/Investor Note: Builders should prioritize integrating offensive security early in development. Investors should be wary of "security theater" and favor solutions that embrace open-source collaboration and address the entire AI application stack.
  3. The "So What?": The accelerating pace of AI development means static security solutions will quickly become obsolete. Proactive, community-driven, and full-stack security research is essential for navigating the next 6-12 months of AI evolution.
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Crypto Podcasts

May 27, 2025

Is Bitcoin Heading To $150k?

1000x Podcast

Crypto
Key Takeaways:
  1. Bitcoin's Bullish Trajectory: Bitcoin is on a path to potentially reach $150k-$200k, supported by a low-hype, strong-setup environment and a more sophisticated investor base.
  2. Strategic Altcoin Hunting: Focus on revenue-generating altcoins with solid fundamentals (check DeFiLlama) and consider measured exposure to the burgeoning AI crypto sector.
  3. Prioritize Self-Custody: Given exchange vulnerabilities, holding your assets offline in cold storage is more critical than ever.
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May 27, 2025

Empire Cross-Post: The Bull Case For Ethereum | Tom Dunleavy & Ryan Berckmans

Bell Curve

Crypto
Key Takeaways:
  1. L1 is HQ: Ethereum's "pivot" reasserts the L1's central role, supported by L2s that offer crucial business model diversity and customization for the world coming on-chain.
  2. Value Accrual via Security & Confidence: ETH's valuation is increasingly tied to the total economic value it secures and the market's confidence in its future, not just direct fee revenue.
  3. Business Development is Crucial: To compete and grow, Ethereum requires a significantly more robust and proactive go-to-market strategy to attract users, institutions, and developers.
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May 27, 2025

The Altseason Rotation Has Begun! Here's The Data Behind the Next Rotation

Bankless

Crypto
Key Takeaways:
  1. Rotation Imminent: Data suggests Bitcoin's strength is setting the stage for capital to flow into altcoins, particularly Ether, which is seen as "hated" and due for a rebound against Bitcoin.
  2. Macro is Bullish (For Now): Continued fiscal spending and an anticipated stablecoin bill are significant tailwinds, though summer may bring some turbulence.
  3. Strategic Allocation is Key: Focus on assets with strong fundamentals or high attention. Consider beta plays like "blue-chip" meme coins (Pepe for ETH, Bonk for SOL) for higher-risk, higher-reward exposure, but plan exits for speculative positions.
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May 27, 2025

Travis Millott: Tao Templar, Bittensor Subnets, Dynamic Tao, Mining, Crypto Education | Ep. 44

Ventura Labs

Crypto
Key Takeaways:
  1. Dynamic Tao is High-Risk: Approach investments with extreme caution; the market is volatile, and significant capital loss is a tangible risk.
  2. Embrace Unpredictable Innovation: Bittensor's core value lies in its capacity to generate unforeseen, groundbreaking solutions from a global, permissionless, and competitive talent pool.
  3. Substrate Chain Decentralization is Critical: The successful decentralization of Bittensor's foundational layer is a paramount upcoming milestone for its long-term viability, security, and censorship resistance.
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May 26, 2025

The Bitcoin Treasury Playbook With Tyler Evans & Josh Solesbury

Empire

Crypto
Key Takeaways:
  1. Global Takeover: Bitcoin treasury strategies are rapidly globalizing, creating new Bitcoin-proxy investment vehicles in numerous capital markets.
  2. Investor Vigilance: While "Bitcoin plus" returns are alluring, investors must critically assess MNAV multiples and beware of highly leveraged companies lacking strong, transparent leadership.
  3. Reverse Tokenization is Real: Crypto assets are increasingly entering traditional finance via these public companies, fundamentally changing institutional access and perception.
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May 26, 2025

Why Analysts Are Valuing ETH All Wrong

Bankless

Crypto
Key Takeaways:
  1. **L1s are Money, Not Stocks:** Stop trying to fit square pegs (L1s) into round holes (DCF models for companies). Their value accrues like money, through network effects and demand for their monetary properties.
  2. **RSOV is Your New Lens:** Use RSOV to gauge the "stickiness" of capital in an L1 ecosystem. A growing RSOV suggests a strengthening monetary base and potentially a rising valuation floor.
  3. **ETH's RSOV Story:** ETH, when viewed through the RSOV lens, appears undervalued relative to assets like Bitcoin, especially considering catalysts like EIP-4844 ("proto-danksharding") and the growth of its L2 ecosystem, which drives ETH's use as a store of value.
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