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AI Podcasts

February 2, 2026

Ben Horowitz and David Solomon: The Sweetest Macro Spot in 40 Years

a16z

AI
Key Takeaways:
  1. Unprecedented fiscal and monetary stimulus, coupled with a deregulatory environment, creates a powerful tailwind for financial assets and tech, driving a capital investment super cycle.
  2. Investors should prioritize companies with proprietary data and GPU access, as these are the new moats in an AI-driven world where traditional software leads are eroding.
  3. The convergence of a stimulative macro environment and AI's disruptive force means capital will flow to those who can scale, innovate, and navigate complex policy landscapes, making strategic positioning now critical for future relevance.
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February 3, 2026

Inside The Biggest Uranium Deal In 50 Years | Scott Nolan, CEO of General Matter

The Generalist

AI
Key Takeaways:
  1. Geopolitical tensions and the insatiable energy demands of the AI revolution are forcing a re-evaluation of national energy security.
  2. Invest in companies applying "first principles" engineering and a commercial cost-reduction mindset to foundational, capital-intensive industries.
  3. The US nuclear fuel supply chain is undergoing a rapid, government-backed revitalization.
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February 3, 2026

OpenClaw Makes AI Agents and CPUs Get Real

Semi Doped

AI
Key Takeaways:
  1. The macro trend of autonomous AI agents is shifting compute demand beyond GPUs, creating an unexpected CPU crunch and forcing a re-evaluation of on-premise inference and cost-optimized model routing for security and efficiency.
  2. Investigate hybrid compute strategies, combining secure local environments (Mac Minis, home servers) with cloud-based LLMs, and explore multi-model API gateways like OpenRouter to optimize agent costs and performance.
  3. AI agents are here, demanding a rethink of your compute stack and security protocols. Prepare for a future where CPU capacity, not just GPU, becomes a critical bottleneck, and strategic cost management for diverse AI models is non-negotiable for competitive advantage.
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February 4, 2026

⚡️ Context graphs: AI’s trillion-dollar opportunity — Jaya Gupta, Ashu Garg, Foundation Capital

Latent Space

AI
Key Takeaways:
  1. The move from general-purpose LLMs to specialized AI agents demands a new data architecture that captures the *why* of decisions, not just the *what*. This creates a new, defensible layer of institutional memory, moving value from raw model IP to proprietary decision intelligence.
  2. Invest in or build agentic systems that are in the *orchestration path* of specific business processes. This allows for the organic capture of decision traces, forming a proprietary context graph that incumbents cannot easily replicate.
  3. Over the next 12 months, the ability to build and extract value from context graphs will define the winners in the enterprise AI space, creating a new "context graph stack" that will be 10x more valuable than the modern data stack.
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February 2, 2026

We Entered an Era Where No One Knows What Comes Next

Turing Post

AI
Key Takeaways:
  1. AI's progress has transitioned from a linear, bottleneck-driven model to a multi-layered, interconnected explosion of advancements. This makes traditional long-term forecasting obsolete.
  2. Prioritize building and investing in adaptable systems and teams that can rapidly respond to emergent opportunities across diverse AI layers. Focus on robust interfaces and composability rather than betting on a single "next frontier."
  3. The next 6-12 months will test our ability to operate in an environment where the future is increasingly opaque. Success will come from embracing this unpredictability, focusing on present opportunities, and building for resilience against an unknowable future.
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February 2, 2026

Ben Horowitz & David Solomon on Why Scale Is The Only Thing That Matters

a16z

AI
Key Takeaways:
  1. The Macro Shift: Unprecedented fiscal and monetary stimulus, combined with an AI-driven capital investment super cycle, creates a "sweet spot" for financial assets and growth technology. This favors institutions with scale and adaptability.
  2. The Tactical Edge: Prioritize investments in companies with proprietary data and significant GPU access, as these are new competitive moats in the AI era. For founders, secure capital to compete against well-funded incumbents.
  3. The Bottom Line: Scale and strategic capital deployment are paramount. Whether a financial giant or tech insurgent, the ability to grow, adapt to AI's new rules, and handle regulatory currents will determine relevance and success.
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February 1, 2026

Google’s AI Stack Is Unmatched (No One Else Is Even Close) w/ Ejaaz

Milk Road AI

AI
Key Takeaways:
  1. The AI industry is consolidating around players with deep, proprietary data and infrastructure, transforming general LLMs into personalized, transactional agents. This means value accrues to those who can not only build powerful models but also distribute them at scale and integrate them into daily life.
  2. Investigate companies building on top of Google's AI ecosystem or those creating niche applications that use personalized AI. Focus on solutions that move beyond simple chatbots to actual task execution and intent capture.
  3. Google's strategic moves, particularly with Apple and in e-commerce, signal a future where AI is deeply embedded in every digital interaction. Understanding this shift is crucial for identifying where value will be created and captured.
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January 31, 2026

State of AI in 2026: LLMs, Coding, Scaling Laws, China, Agents, GPUs, AGI | Lex Fridman Podcast #490

Lex Fridman

AI
Key Takeaways:
  1. The AI industry is pivoting from a singular AGI pursuit to a multi-pronged approach, where specialized models, advanced post-training, and geopolitical open-source competition redefine competitive advantage and talent acquisition.
  2. Invest in infrastructure and expertise for advanced post-training techniques like RLVR and inference-time scaling, as these are the primary drivers of capability gains and cost efficiency in current LLM deployments.
  3. The next 6-12 months will see continued rapid iteration in AI, driven by compute scale and algorithmic refinement rather than architectural overhauls. Builders and investors should focus on specialized applications, human-in-the-loop systems, and the strategic implications of open-weight models to capture value in this evolving landscape.
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January 31, 2026

Inside a Chinese AI Lab: How MiniMax Builds Open Models

Turing Post

AI
Key Takeaways:
  1. The open-source AI movement is democratizing access to powerful models, but this decentralization shifts the burden of safety and robust environmental adaptation from central labs to individual builders.
  2. Prioritize investing in or building tools that provide robust, scalable evaluation and alignment frameworks for open-weight models.
  3. The next 6-12 months will see a race to solve environmental adaptability and human alignment in open-weight agentic AI. Success here will define the practical utility and safety of the next generation of AI applications.
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Crypto Podcasts

July 22, 2025

Trading Bitcoin Cycles With Willy Woo

1000x Podcast

Crypto
Key Takeaways:
  1. Don't Get Sidelined. Most of the cycle's gains happen in a handful of days. Trying to trade in and out of a bull market is a high-risk strategy that can easily leave you behind.
  2. Watch the Macro Clock. The Bitcoin cycle top will be dictated by the timing of the global business downturn. This, not internal metrics, is the primary indicator to watch.
  3. Use Price Levels as Triggers, Not Targets. If the macro downturn hits this year, a cycle top in the $140k-$160k range is plausible. Use these levels to re-evaluate risk rather than trying to perfectly time an unknowable peak.
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July 23, 2025

CRYPTOCURRENCY TALK: TALOS, PUMP, ETHENA, HYPERLIQUID - 0xResearch and Friends

0xResearch

Crypto
Key Takeaways:
  1. Product Is King. The market consistently rewards applications that prioritize a simple, effective user experience. Hyperliquid’s mobile integration and the rise of intents-based bridging show that abstract infrastructure plays are losing ground to products that just work.
  2. Incentives Need a Narrative. Pump.fun’s gigantic treasury is a powerful tool, but without a clear strategy and strong communication from the team, it's not enough to prevent a massive loss of market share and investor confidence.
  3. De-Risking Is the New Black. Mature protocols like Ethena are actively moving to reduce complexity and risk, even at the cost of marginal yield. This signals a broader shift towards sustainability and resilience over chasing every last basis point.
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July 22, 2025

Empire Cross-Post: DC Crypto Week Takeaways With Rebecca Rettig & Alexander Grieve

Bell Curve

Crypto
Key Takeaways:
  1. Stablecoins are Mainstream Infrastructure. The Genius Act solidifies stablecoins as a key pillar of the future financial system. For founders and investors, the largest immediate opportunities are in building white-label issuance platforms and other ancillary services for traditional companies.
  2. ICOs Are Back, But With Guardrails. The Clarity Act paves the way for a resurgence in token pre-sales by creating a compliant fundraising path. Founders gain a new capital formation tool, while investors get a clearer framework, albeit with longer lockups for insiders.
  3. The Next Battle is Taxes. With stablecoin and market structure frameworks advancing, the next major regulatory hurdle is tax. Expect a significant push to clarify the tax treatment of staking rewards and other on-chain activities, which will be critical for integration into products like ETFs.
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July 22, 2025

The Truth Behind Crypto Market Makers | Matt Jobbé-Duval

Lightspeed

Crypto
Key Takeaways:
  1. The Call Option's Double Edge: The standard call-option deal is an elegant solution to crypto's volatility, but it becomes toxic when the loan is too large. An oversized option creates a "magnet effect" where the price gets pinned to the strike, killing healthy price discovery.
  2. "Active Market Making" Is a Trap: Selling the future to pump the present is a fool's game. This structure leverages a project’s future token supply for a short-term price pump that almost always ends in a perp-driven death spiral, destroying credibility.
  3. Launch Price Is Vanity, Momentum Is Sanity: The initial TGE price is an illusion driven by retail FOMO. Projects should focus on establishing a fair pre-launch price and using stabilization mechanisms to build sustained momentum, rather than chasing a fleeting, sky-high valuation on day one.
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July 22, 2025

Bits and Bips LIVE: July 21

Unchained

Crypto
Key Takeaways:
  1. Stablecoin Infrastructure is the New Gold Rush: The Genius Act fired the starting gun. The most significant opportunities lie not in issuing stablecoins, but in building the ecosystem around them—from payment rails to wallet design and tokenized money market funds.
  2. Narrative is the Ultimate Catalyst: ETH’s rally wasn’t driven by a tech breakthrough but by a potent cocktail of treasury-driven demand and a leadership refresh. In crypto, momentum creates its own demand.
  3. The Great Convergence is Accelerating: With Coinbase in the S&P 500 and a wave of crypto IPOs, traditional capital can no longer sit on the sidelines. The primary battleground is now for public market mindshare.
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July 21, 2025

Where Are We In The Cycle? | Willy Woo

1000x Podcast

Crypto
Key Takeaways:
  1. We are in a high-risk, high-reward phase where liquidity is the primary driver. The cycle's ultimate peak remains uncertain and heavily dependent on macro-economic policy.
  2. Brace for the Parabola. This is the late-stage bull market, where the most significant gains historically occur in short, violent bursts. Being out of the market means risking missing the entire cycle's payoff.
  3. Rotation Is in Motion. Capital has started flowing from Bitcoin to Ethereum. The next domino to watch for is a pop in large-cap alts, which would confirm a full-blown alt season is underway.
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