**Invest at the Intersection.** The alpha in AI investing will be found not in crowded SaaS applications but in "Silicon Valley blind spots"—complex industries like biology where AI can bridge the digital and physical worlds.
**Augment, Don't Annihilate.** The winning go-to-market strategy for AI is the copilot model. Frame products as tools that amplify human capability, making experts more productive and profitable, rather than threatening their jobs.
**Judge the Trajectory, Not the Snapshot.** Don't dismiss AI based on a single, past failure. Its capability curve is exponential. What seems like a limitation today will likely be a solved problem tomorrow, demanding continuous engagement to keep pace.
Benchmarks Are Broken. Leaderboards like LMArena are flawed proxies for model quality, skewed by selection bias and susceptible to Goodhart's Law. High scores don’t equal a good user experience.
Human Feedback is Infrastructure. The future isn't about removing humans but orchestrating them effectively. Treating high-quality, representative human feedback as a core, API-driven part of the development lifecycle is non-negotiable.
Alignment is a Moving Target. Agentic misalignment is a present-day reality, not a distant sci-fi threat. The more capable models become, the wider the gap grows between their emergent goals and our intended instructions.
Influence Over Impressions: The model shifts focus from easily gamed metrics like views and likes to verifiable signals of influence—watch time on YouTube and PageRank-based authority on X.
Revenue-Driven Tokenomics: All platform revenue is used to buy back and burn the ALPHA token, creating a powerful, deflationary flywheel as adoption grows.
Targeted, Scalable Marketing: Bitcast enables brands to programmatically deploy campaigns across hundreds of niche influencers, reaching highly engaged communities with a consistency and scale that legacy agencies cannot match.
**Incumbency Is a Liability:** Big Tech's legacy products, distribution advantages, and corporate cultures are being systematically dismantled by faster, AI-native upstarts.
**Reinvent Markets from First Principles:** Success in intractable fields—from geopolitics to real estate—comes from questioning assumptions, not relying on domain experts who perpetuate the status quo.
**Unwind Stupidity Before Innovating:** The fastest path to value creation is often simply reversing a series of terrible decisions made by prior leadership.
**Scrutinize the AI Plumbing.** Investors must look past headline revenue and analyze the quality of transactions. Deals like in-kind credits and obscure service-level agreements (like Nvidia’s backstop for Coreweave) can mask true market demand.
**Stablecoins Are the Real Disruption.** The explosion in stablecoin usage represents a fundamental challenge to the high-fee, slow-settlement models of Visa, Mastercard, and traditional banks. This is the crypto use case that is finally breaking into the mainstream.
**Federal Preemption for AI is Non-Negotiable.** A patchwork of state-level AI laws will cripple U.S. innovation. A single, national regulatory framework is the only path to maintaining global leadership.
Look Beyond the Chatbot. Judge AI progress not by its daily performance, but by its ability to solve novel problems in science and math—where models are now pushing the frontiers of human knowledge.
The Bottleneck is Human, Not Silicon. AI's capacity for automation is growing exponentially (task length is doubling every ~4 months). The real limit to adoption is organizational will and the ability to effectively delegate complex work.
Prepare for a Weirder World. The biggest risk is underestimating the pace of change. As agent capabilities expand, so do unpredictable "weird behaviors" like scheming and deception, creating a future that requires active imagination and risk management.
Verification Over Creation: A proof that can be widely verified, even if computer-generated, holds more democratic value than a human proof understood by only a few elites.
Humans Ask, AI Answers: The primary role for mathematicians in an AI-augmented world is to pose the right questions and conjectures, leaving the computational heavy lifting to their AI assistants.
The Greatest Risk is Us: The biggest threat isn't rogue AI but our own tendency to over-hype and blindly trust flawed tools, leading to the spread of misinformation disguised as mathematical fact.
LLMs are Navigators, Not Discoverers. They are masters of interpolation within their training data but are architecturally bound from making the intuitive leaps required for true scientific breakthroughs. Don’t expect a Transformer to produce the next theory of relativity.
The Innovation Plateau is Real. Simply throwing more data and compute at current architectures will only "smoothen out" existing knowledge manifolds, not create new ones. This path leads to incremental gains, like an iPhone getting a better camera, not a paradigm shift.
Entropy is the Key to Control. For developers, effective prompting is entropy management. By crafting specific, context-rich prompts, you reduce the model's prediction entropy, forcing it onto a confident, low-hallucination path to a reliable output.
Trust is the New Commodity. Targon’s use of TEEs shifts security from a software promise to a cryptographic hardware guarantee. This verifiable privacy is the key to unlocking enterprise adoption for decentralized AI.
The Crucible Creates Diamonds. Bittensor's adversarial environment forced Targon to build an unexploitable system. This has turned a historical pain point ("PTSD from miners") into a core competitive advantage, resulting in a uniquely resilient platform.
From Backroom Deals to a Liquid Market. By launching a self-serve platform with a transparent order book, Targon is attacking the compute market's core inefficiency: opaque pricing. Their vision extends to compute derivatives, aiming to turn compute power into a globally tradable asset.
Regulatory Thaw: The SEC’s new leadership signals a more accommodating stance on crypto, potentially unlocking significant growth for DeFi in the US.
Market Structure Evolution: Tokenization is increasingly viewed as the key to modernizing capital markets, with on-chain IPOs and improved secondary market liquidity on the horizon.
Infrastructure is King: Acquisitions like Privy by Stripe highlight the race to build and control the foundational layers of the crypto economy, especially around wallets and stablecoins.
Solana's Next Act is Crucial: Current memecoin activity, while impressive, is viewed by institutions like Standard Chartered as less sustainable than diversified utility; a pivot to tokenized equities or social is key for long-term valuation.
Perception Battles Performance: Ethereum's established "trustworthiness" gives it an institutional edge, even if Solana offers superior tech for certain applications. Solana must overcome its "memecoin" image to attract serious TradFi.
Near-Term Headwinds for Solana Relative to Ethereum: Kendrick suggests Ethereum might outperform Solana in the near term (though both underperform Bitcoin) as Solana navigates its transition phase, while Ethereum benefits from incumbency in stablecoins and tokenized RWAs.
**Currency Cold War:** A "currency conflict" is unfolding, with the winner set to define the financial backbone of the next-gen internet and global commerce.
**Stablecoins vs. The State:** USD stablecoins are pitched as the West's best bet for the internet's future currency, directly competing with state-backed digital currencies like China's e-CNY.
**Agent-Powered Internet:** The dream is an internet where AI agents, fueled by ultra-low-cost stablecoin transactions, manage our digital lives, moving incentives away from human attention.
**Solve Real Friction:** The "last-mile" challenge—seamlessly converting stablecoins to local cash in emerging markets—remains the critical bottleneck and prime opportunity for stablecoin protocols.
**Moats are Real:** Overcoming established players like Tron requires more than just better tech or lower fees; it demands superior distribution and user migration strategies.
**Align Incentives:** Morpho's structural changes offer a compelling model for aligning team, investor, and token holder interests, potentially setting a new standard for Web3 projects.
Deficit Tailwinds: Persistent global fiscal deficits are expected to continue fueling appreciation in risk assets, including cryptocurrencies.
Stablecoin Tsunami: Stablecoins are not just a crypto niche but a fundamental disruptor to the traditional banking system, with significant investment flowing into leaders like Circle, despite valuation concerns.
App-Layer Alpha: Value is increasingly found in specific applications (like Pump.Fun) and companies leveraging crypto (like Galaxy Digital's AI/crypto blend), sometimes even diverting attention from base-layer L1 tokens.
