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AI Podcasts

December 26, 2025

What I learned at the frontier of tech in 2025 (Kelly, Cowen, Wang, Prince)

Azeem Azhar

AI
Key Takeaways:
  1. The Macro Pivot: The transition from weightless software to energy-heavy hardware.
  2. The Tactical Edge: Stop building "wrappers" for model weaknesses.
  3. The Bottom Line: AI value is moving from the model to the grid and the individual reputation.
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December 26, 2025

How AI Will Reshape The Economy In 2026 (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. The Macro Shift: The Great Re-architecting. As legacy software moats evaporate and industrial supply chains reshore, value is migrating from passive data storage to active execution layers.
  2. The Tactical Edge: Target Archaic Verticals. Identify high-friction industries like mortgage servicing or IT support where the distance between intent and execution is currently measured in days.
  3. The Bottom Line: The next two years will reward those who build systems of action that replace human labor with autonomous agents and software-defined hardware.
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December 27, 2025

Why Scientists Can't Rebuild a Polaroid Camera [César Hidalgo]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The Macro Trend: Economic complexity predicts growth better than current GDP. Capital will move toward "high-letter" economies like India and Indonesia.
  2. The Tactical Edge: Prioritize team retention over documentation. Since knowledge is embodied, losing a core team is equivalent to deleting the source code.
  3. The Bottom Line: Success in the next decade belongs to those who treat knowledge as a living network rather than a digital asset.
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December 26, 2025

⚡️GPT5-Codex-Max: Training Agents with Personality, Tools & Trust — Brian Fioca + Bill Chen, OpenAI

Latent Space

AI
Key Takeaways:
  1. The Macro Shift: Agentic Abstraction. We are moving from Model-as-a-Service to Agent-as-a-Service where the harness is as important as the weights.
  2. The Tactical Edge: Standardize your CLI. Use tools like ripgrep (RG) that models already have "habits" for to see immediate performance gains.
  3. The Bottom Line: The next 12 months will see the end of manual integration engineering as agents become capable of navigating UIs and legacy terminals autonomously.
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December 26, 2025

Steve Yegge's Vibe Coding Manifesto: Why Claude Code Isn't It & What Comes After the IDE

Latent Space

AI
Key Takeaways:
  1. The commoditization of syntax means architectural judgment is the only remaining moat. As the cost of code hits zero the value of intent skyrockets.
  2. Replace your manual refactoring workflows with a burn and rebuild strategy. Use agents to generate entirely new modules instead of patching old ones.
  3. Seniority is no longer a shield against obsolescence. You must spend the next six months building your agentic intuition or risk being replaced by a PhD student with a prompt.
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December 28, 2025

One Year of MCP — with David Soria Parria and AAIF leads from OpenAI, Goose, Linux Foundation

Latent Space

AI
Key Takeaways:
  1. The Macro Evolution: Standardized communication layers are replacing custom API integrations. This commoditizes the connector market and moves value to the models that best utilize these tools.
  2. The Tactical Edge: Standardize your internal data tools using MCP servers today. This ensures your company is ready for autonomous agents that can discover and use your resources without manual API integration.
  3. The Bottom Line: The agentic stack is consolidating around MCP. Interoperability is no longer a feature; it is the foundation for the next decade of AI utility.
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December 26, 2025

How Claude Code Works - Jared Zoneraich, PromptLayer

AI Engineer

AI
Key Takeaways:
  1. The transition from Prompt Engineering to Context Engineering where the goal is keeping the model's workspace small and relevant.
  2. Replace your complex classification prompts with a single Bash tool. Let the agent write its own Python scripts to handle data transformations.
  3. The winners in the agent space will not be those with the most complex logic. They will be the ones who build the best tools for the model to use.
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December 26, 2025

Shipping AI That Works: An Evaluation Framework for PMs – Aman Khan, Arize

AI Engineer

AI
Key Takeaways:
  1. The Macro Shift: From Model-Centric to Eval-Centric. The value is moving from the LLM itself to the proprietary evaluation loops that keep the LLM on the rails.
  2. The Tactical Edge: Export production traces and build a "Golden Set" of 50 hard examples. Use these to run A/B tests on every prompt change before hitting production.
  3. The Bottom Line: Reliability is the product. If you cannot measure how your agent fails, you haven't built a product; you've built a demo.
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December 26, 2025

How AI Will Reshape The Economy In 2026 (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. The transition from passive data storage to active agentic execution across both financial and industrial sectors.
  2. Target unsexy legacy industries like mortgage servicing or rare earth processing where the margin for improvement is highest.
  3. 2026 marks the year where software eating the world moves from the screen to the physical supply chain and the autonomous agent.
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Crypto Podcasts

October 15, 2025

Crypto's Biggest Liquidation, DAT Strategies, & The Purification Trade | Jeff Park

Forward Guidance

Crypto
Key Takeaways:
  1. Consolidation is Coming: The recent retail wipeout will likely funnel capital into higher-quality assets, with Bitcoin positioned to front-run altcoins in a reversal of typical bull market cycles.
  2. Reframe Debasement as Purification: The simultaneous rise of gold and Bitcoin isn't just a hedge; it's a fundamental repricing of value and a cleansing of a broken financial system, driven by geopolitical strategy.
  3. DATs are Not ETFs: Digital Asset Treasuries offer an active approach to crypto exposure, with smaller players uniquely positioned to capture on-chain alpha that is impossible for mega-holders to access.
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October 13, 2025

The Most Important Video I’ll Make This Year

Taiki Maeda

Crypto
Key Takeaways:
  1. **The Game Has Changed.** Stop trying to win by spot-buying overvalued altcoins in a market dominated by insiders. The real, sustainable edge is found on-chain through airdrop farming, which allows you to acquire tokens at a low cost basis and sell them to market hype.
  2. **Become an All-Weather Farmer.** Structure your portfolio defensively. A 50%+ stablecoin allocation is not being sidelined; it's a dry powder reserve that allows you to farm, hedge, and survive while others get wiped out. Your upside comes from farming, not from being 100% long.
  3. **Airdrops Are Your Asymmetric Bet.** Treat airdrop points as a call option on the entire crypto market. This allows you to stay risk-off with a large stablecoin position while retaining explosive upside potential if the market runs, creating a win-win scenario.
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October 14, 2025

LIVE from Digital Asset Summit

Forward Guidance

Crypto
Key Takeaways:
  1. The Crash Was Technical, Not Existential: This wasn't another Luna. It was a liquidity-driven cascade originating from centralized exchanges that wiped out leveraged retail, while DeFi infrastructure proved its mettle. The fundamental bull case remains intact.
  2. Bitcoin is a Different Animal: The stark performance divergence between a resilient Bitcoin and collapsing altcoins is the clearest signal yet that BTC now plays in a different, institutionalized league. The speculative fervor in "useless alts" is dead for the foreseeable future.
  3. Institutions Are Buying the Debasement Story, Not the Dip: Professional investors, insulated by ETFs, completely missed the weekend's volatility. Their focus is unchanged: allocating more capital (now 3-5%) to the "purification trade" as a hedge against unstoppable fiat debasement.
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October 11, 2025

ETH Supply Shock Could Ignite Explosive Rally

Forward Guidance

Crypto
Key Takeaways:
  1. Supply Shock Imminent: Corporate ETH accumulation is happening faster and with greater relative market impact than Bitcoin's history, creating a coiled spring for price.
  2. The Stage is Set: Profit-taking from old holders is complete, hype has died down, and leverage has been wiped out. The path of least resistance for ETH is now up.
  3. Follow the Smart Money: ETH is not just a crypto play; it's a macro-correlated, high-beta bet endorsed by some of the world's sharpest investors.
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October 10, 2025

CRYPTO MARKET CRASH EMERGENCY LIVESTREAM

Taiki Maeda

Crypto
Key Takeaways:
  1. Survive First, Profit Later. The market always presents new opportunities, but only for those who preserve capital. Avoid leverage and hold significant stablecoin allocations to capitalize on moments of extreme fear, not become a victim of them.
  2. Find Your Asymmetric Edge: Farm, Don't Buy. Retail investors cannot out-trade funds with insider information. The real edge is in airdrop farming—getting into promising protocols early and selling the token to the masses who buy on inflated centralized exchange listings.
  3. The Altcoin Reckoning is Here. The belief that a rising Bitcoin lifts all boats is a dangerous assumption. Most alts are overvalued and lack a fundamental thesis beyond momentum. Prepare for a future where Bitcoin grinds higher while most of the altcoin market bleeds out.
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October 10, 2025

Polymarket's $2B Deal with ICE Changes Everything | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Founder Vision Outweighs Everything. Polymarket’s story proves that a founder with an unwavering, maniacal vision can overcome technical hurdles, regulatory threats, and brutal bear markets. Shane won by being an unstoppable evangelist.
  2. Abstraction Is the Key to Mass Adoption. The best crypto apps don't feel like crypto apps. Polymarket’s success comes from hiding the blockchain complexity, a lesson for every builder aiming for mainstream relevance.
  3. Bet on Second-Order Effects. The surge in BNB isn't about BSC's tech; it's a proxy bet on CZ's return. Smart investors look past the immediate narrative to trade the powerful undercurrents shaping the market.
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