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AI Podcasts

February 3, 2026

Why The Laws of Startup Physics Have Changed | Ben Horowitz Interview

Invest Like The Best

AI
Key Takeaways:
  1. The Macro Shift: AI is collapsing the time horizon for technological deployment and market dominance, shifting the competitive advantage from pure innovation to a combination of innovation, capital, and rapid infrastructure deployment.
  2. The Tactical Edge: Invest in companies that are not just building AI, but are fundamentally rethinking existing industries with AI-first principles, recognizing that traditional software moats are eroding.
  3. The Bottom Line: The next 12-24 months will see AI's broad impact kick in, creating unprecedented opportunities for those who understand its new "laws of physics" and the critical role of policy in shaping its trajectory.
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February 4, 2026

Ozempic Won't Solve America's Obesity Problem

a16z

AI
Key Takeaways:
  1. The healthcare system is moving from reactive, acute care to proactive, preventative interventions, driven by the unsustainable costs of chronic disease and a growing understanding of environmental health.
  2. Build infrastructure that financially incentivizes lifestyle interventions, such as TrueMed's HSA/FSA payment rails for health-promoting products and services.
  3. The next decade will see hundreds of billions of dollars redirected towards preventative health. Companies that bridge the gap between lifestyle choices and healthcare financing will capture significant market share.
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February 3, 2026

SpaceX Engineer Explains America's Biggest Energy Mistake | Scott Nolan, CEO of General Matter

The Generalist

AI
Key Takeaways:
  1. The Macro Shift: Global energy demand, driven by AI, forces a strategic re-evaluation of nuclear power. This creates a window for nations to re-shore critical energy infrastructure, moving from reliance on adversaries to domestic, cost-competitive solutions.
  2. The Tactical Edge: Investigate companies addressing foundational supply chain gaps in critical industries like energy. Look for teams with a "first principles" engineering approach and a track record of commercializing hard tech.
  3. The Bottom Line: America's energy independence and its ability to power future technological growth, like AI, hinge on rebuilding domestic nuclear fuel enrichment. This is not just an industrial opportunity; it is a national security imperative.
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February 4, 2026

The Economic Singularity Will Make Today’s Economy Unrecognizable w/ Dr. Alexander Wissner-Gross

Milk Road AI

AI
Key Takeaways:
  1. The Macro Shift: AI-driven hyperdeflation is colliding with the technical reality of autonomous AI agents creating their own crypto-backed economies, threatening a decoupling from human fiat systems.
  2. The Tactical Edge: Investigate and build infrastructure that bridges human and AI economies, focusing on fiat-to-crypto rails that can accommodate agent-driven transactions to prevent a complete split.
  3. The Bottom Line: The next 5-10 years will see an unprecedented economic transformation. Understanding AI's deflationary power and the emerging AI agent economy is critical for navigating a world where traditional economic models may no longer apply.
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February 3, 2026

OpenClaw Makes AI Agents and CPUs Get Real

Semi Doped

AI
Key Takeaways:
  1. The time of practical AI agents is here, moving compute demand beyond pure GPU inference to a significant reliance on CPUs for coordination, data handling, and security.
  2. Evaluate your agent deployment strategy now, prioritizing sandboxed environments (VPS, dedicated local servers) and exploring cost-optimized model routing to manage API expenses.
  3. Prepare for a future where AI agents become integral to workflows, but recognize the hidden infrastructure costs and security implications, particularly the growing importance of CPU capacity and robust access controls.
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February 4, 2026

⚡️ Context graphs: AI’s trillion-dollar opportunity — Jaya Gupta, Ashu Garg, Foundation Capital

Latent Space

AI
Key Takeaways:
  1. The shift from "how" to "why" in AI agent capabilities creates a new, multi-trillion-dollar market for companies that can capture institutional decision logic.
  2. Invest in or build agentic systems that are in the "right path" of business processes, actively capturing decision traces from unstructured data.
  3. Hundreds of context graphs will be in production at scale within a year, defining a new "context graph stack." The winning companies will be those that master this flywheel, extracting value to accelerate automation and build deep, defensible moats.
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February 2, 2026

We Entered an Era Where No One Knows What Comes Next

Turing Post

AI
Key Takeaways:
  1. The shift from linear, bottleneck-driven technological progress to a multi-layered, interconnected advancement model in AI has rendered traditional forecasting obsolete, forcing a re-evaluation of what "singularity" truly represents.
  2. Prioritize adaptability: Invest in modular, composable AI infrastructure and tools that thrive in multi-layered, unpredictable environments, rather than betting on single-bottleneck solutions.
  3. The inability to narrate AI's future means traditional roadmaps are obsolete; success hinges on navigating simultaneous, interconnected advancements and embracing the emergent.
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February 3, 2026

Why The Laws of Startup Physics Have Changed | Ben Horowitz Interview

Invest Like The Best

AI
Key Takeaways:
  1. The era of infrastructure-heavy tech deployment is over; AI's internet-native nature means immediate, widespread application. This shifts the competitive advantage from capital-intensive builds to rapid iteration and data leverage.
  2. Invest in companies that are not just using AI, but are fundamentally rethinking their business models around AI's ability to collapse traditional cost structures and accelerate product development.
  3. AI is a force multiplier for both individual opportunity and national power. Understanding its immediate deployability and the new rules of company building is crucial for investors and builders aiming to lead in the next wave of innovation over the next 12-24 months.
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February 2, 2026

Ben Horowitz and David Solomon: The Sweetest Macro Spot in 40 Years

a16z

AI
Key Takeaways:
  1. Unprecedented fiscal and monetary stimulus, coupled with a deregulatory environment, creates a powerful tailwind for financial assets and tech, driving a capital investment super cycle.
  2. Investors should prioritize companies with proprietary data and GPU access, as these are the new moats in an AI-driven world where traditional software leads are eroding.
  3. The convergence of a stimulative macro environment and AI's disruptive force means capital will flow to those who can scale, innovate, and navigate complex policy landscapes, making strategic positioning now critical for future relevance.
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Crypto Podcasts

October 10, 2025

Why This Early Solana Investor Is Still All In | Viktor Fischer

Lightspeed

Crypto
Key Takeaways:
  1. **The L1 War Is Won.** Don't bet on new L1s. The network effects, developer mindshare, and ecosystem infrastructure of chains like Solana and Base have created an insurmountable moat.
  2. **DATs Are the Trojan Horse for TradFi.** Digital Asset Treasury companies are the key to unlocking Wall Street capital. Expect Solana DATs to drive a massive TVL re-rating in 2026 as their superior yield generation becomes undeniable.
  3. **SOL to $2,000 Is the Base Case.** This price target isn't based on meme-fueled hype, but on a model where Solana captures just 10% of the projected multi-trillion-dollar tokenized asset market by 2030.
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October 9, 2025

Andre Cronje: How the SEC Tried to Shut Me Down

The DCo Podcast

Crypto
Key Takeaways:
  1. Regulation by Exhaustion: The SEC's primary weapon was not legal action but a relentless process designed to drain builders' time, energy, and will to continue.
  2. The Target Is Always Moving: Regulators will continuously shift their focus—from token to revenue to the product itself—until they find a viable angle of attack.
  3. Innovation Was the Real Target: This "shotgun approach" against hundreds of projects was a de facto industry crackdown that successfully chased many legitimate builders away, achieving a policy goal without ever going to court.
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October 8, 2025

The BTC/Gold Ratio Is Screaming "Higher"

1000x Podcast

Crypto
Key Takeaways:
  1. Stop Pricing in Fiat: The BTC/Gold ratio is the clearest signal of Bitcoin’s fundamental adoption, stripping away the distortion of dollar debasement.
  2. Mean Reversion Points to $150k+: The established BTC/Gold trend channel since 2023 is screaming higher. A simple return to the channel’s midpoint targets a $150k–$160k Bitcoin price by year-end.
  3. Gold's Rally is Bitcoin's Tailwind: Gold’s new role as a de-dollarization hedge for nations and the subsequent portfolio rebalancing from gold profits into BTC create powerful dual-demand drivers for Bitcoin.
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October 8, 2025

Steady Lads Live From TOKEN2049 in Singapore! w/ Dim Selk

Steady Lads Podcast

Crypto
Key Takeaways:
  1. Profit, Don't HODL. The current market is a trader’s paradise, not an investor’s dream. The strategy is to ride the seasonal Q4 pump and exit by January, refusing to get caught in another brutal bear cycle.
  2. Fade the Old, Farm the New. Capital is mercenary, flowing from established tokens to the next hot airdrop farm or launch. The relentless hunt for volatility means older coins are treated as exit liquidity for the next shiny object.
  3. Unlocks Are the Silent Killer. Before investing, map out the token unlock schedule. Even fundamentally sound projects with strong revenue face a massive gravitational pull on their price from insider and team unlocks.
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September 17, 2025

FinTech Meets Crypto: The Future of Global Payments

Bankless

Crypto
Key Takeaways:
  1. **Stablecoins Are Rebranding Crypto.** The FinTech industry is adopting stablecoin technology not as a niche crypto asset, but as the foundational layer for "FinTech 3.0," poised to overhaul global payments.
  2. **The EVM Is The New COBOL.** Specialized payments chains are standardizing the EVM as the backend for modern finance, creating high-throughput, compliant on-ramps that will bring trillions in TradFi volume on-chain.
  3. **Payments Are Just The Beginning.** Once the world rebuilds its payments infrastructure on stablecoins, the floodgates will open for the complete tokenization of all financial assets, forever blurring the line between crypto and finance.
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September 16, 2025

Collector Crypt: Onchain Capital Markets On Solana | Tuomas Holmberg

Lightspeed

Crypto
Key Takeaways:
  1. Onchain Rails Create New Economies. By digitizing physical assets on high-performance chains like Solana, you eliminate friction around custody, settlement, and global access, unlocking novel business models like the Gotcha Machine.
  2. Real-World Logistics Are the Ultimate Moat. While anyone can build a smart contract, Collector Crypt’s defensibility comes from its physical supply chain—dealer relationships and automated acquisition tools that secure inventory below market price.
  3. Novel Oracles Unlock the Next Wave of DeFi. The future of onchain finance depends on reliably pricing illiquid, real-world assets. Developing proprietary oracles, like Collector Crypt’s, is the first step to building DeFi for everything.
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