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AI Podcasts

December 31, 2025

AI in 2026: 3 Predictions For What’s To Come (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. The Macro Pivot: Outcome-Based Intelligence. We are moving from AI as a Service to Results as a Service where software value is tied to revenue generation rather than seat licenses.
  2. The Tactical Edge: Verticalize the Data. Build in sectors with non-public outcome data to create a compounding moat that resists commoditization by foundation models.
  3. The winners of 2026 will be those who use AI to solve core human needs for connection and discovery while building defensible, data-rich business models.
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December 31, 2025

AutoGrad Changed Everything (Not Transformers) [Dr. Jeff Beck]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The Macro Transition: Moving from "Big Model" monoliths to "Lots of Little Models" where distributed Bayesian assets represent specific physical objects.
  2. The Tactical Edge: Prioritize "Object-Centered" architectures that track uncertainty. This allows robots to "phone a friend" when encountering novel data.
  3. The LLM era is hitting a wall of implicit representation. The next 12 months belong to those building explicit, causal world models grounded in physics rather than language.
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December 31, 2025

[State of Post-Training] From GPT-4.1 to 5.1: RLVR, Agent & Token Efficiency — Josh McGrath, OpenAI

Latent Space

AI
Key Takeaways:
  1. The move from "bigger is better" to "smarter is cheaper" as token efficiency becomes the primary metric for agentic success.
  2. Prioritize building on models that demonstrate high performance on "graph walk" evals to ensure your long-context applications actually work.
  3. Utilitarian and efficient models that prioritize task completion over cheery personality will dominate the developer market.
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December 31, 2025

[State of Evals] LMArena's $100M Vision — Anastasios Angelopoulos, LMArena

Latent Space

AI
Key Takeaways:
  1. The Macro Trend: The transition from static benchmarks to live human-in-the-loop evaluation. As models saturate fixed tests, the only remaining signal is subjective human preference at scale.
  2. The Tactical Edge: Monitor secret model drops on Arena to spot frontier capabilities before official releases. This provides a lead time advantage for builders choosing their tech stack.
  3. The Bottom Line: Arena is the new kingmaker. If you are building AI products, their expert-tier data is the most reliable map for navigating the frontier.
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December 31, 2025

[State of Context Engineering] Agentic RAG, Context Rot, MCP, Subagents — Nina Lopatina, Contextual

Latent Space

AI
Key Takeaways:
  1. The move from small models to medium models (15B to 70B) suggests that reasoning capability is outstripping the desire for low-latency edge deployment.
  2. Implement instruction-following re-rankers to prune your context window. This prevents the model from getting confused by irrelevant data.
  3. Stop building toys. The next year belongs to those who can build full agentic systems that handle billions of tokens without losing the plot.
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December 31, 2025

[NeurIPS Best Paper] 1000 Layer Networks for Self-Supervised RL — Kevin Wang et al, Princeton

Latent Space

AI
Key Takeaways:
  1. The wall between RL and self-supervised learning is crumbling, leading to a unified "representation-first" approach to AI.
  2. Swap your reward-heavy objectives for contrastive representation learning to access deeper, more stable architectures.
  3. If you aren't planning for RL models with 100x the current depth, you're building for the past.
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December 31, 2025

[State of AI Papers 2025] Fixing Research with Social Signals, OCR & Implementation — Team AlphaXiv

Latent Space

AI
Key Takeaways:
  1. Academic research is transitioning from a "publish or perish" PDF culture to an "implement or ignore" code culture.
  2. Use AlphaXiv to filter research by social signal and implementation ease rather than just keyword relevance.
  3. The PDF is an antiquated artifact. In 2025, the value of a paper is measured by the speed at which a developer can spin up its Docker container.
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December 31, 2025

[State of MechInterp] SAEs in Production, Circuit Tracing, AI4Science, "Pragmatic" Interp — Goodfire

Latent Space

AI
Key Takeaways:
  1. The Macro Trend: The transition from black box scaling to transparent steering. As models enter regulated industries, the ability to prove why a model made a decision becomes more valuable than the decision itself.
  2. The Tactical Edge: Deploy sidecar models for monitoring. Instead of using expensive LLM-as-a-judge prompts, probe specific internal features to catch hallucinations at the activation level.
  3. The Bottom Line: The next year belongs to the pragmatic researchers. If you cannot explain your model's reasoning, you will not be allowed to deploy it in high-stakes environments.
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December 31, 2025

[State of Code Evals] After SWE-bench, Code Clash & SOTA Coding Benchmarks recap — John Yang

Latent Space

AI
Key Takeaways:
  1. The transition from completion to agency requires moving from static repos to active, economically valuable environments.
  2. Prioritize agentic workflows that emphasize codebase understanding over simple code generation.
  3. The next 12 months will see a move from stunt autonomy to integrated human-AI systems that handle long-running tasks without losing the human intent.
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Crypto Podcasts

October 22, 2025

Is the Cycle Over, Portfolio Psychology, & Prediction Market Alpha

1000x Podcast

Crypto
Key Takeaways:
  1. Fade the Cycle Narrative: The influx of new, cycle-agnostic capital via ETFs means the market's rhythm has changed. Sideways price action is the new up, signaling strong demand is absorbing OG selling.
  2. Buy Picks, Shovels, and Yield: The era of riding hyped, valueless memecoins is over. The durable strategy is to own the infrastructure (Robin Hood) or assets that generate and return real fees to holders (Shuffle, Aerodrome).
  3. Arbitrage Information Gaps: Find your edge in niche markets. Exploitable alpha exists in prediction markets, whether through contrarian betting, language advantages, or AI-powered analysis.
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October 22, 2025

State Of Crypto 2025 | a16z Crypto — Eddy Lazzarin & Daren Matsuoka

Bankless

Crypto
Key Takeaways:
  1. Stablecoins Are The Trojan Horse. They have achieved undeniable product-market fit, rivaling legacy payment rails and becoming a key tool for U.S. dollar dominance. They are the gateway for both institutional players and everyday users in emerging markets.
  2. Usage is Divorced From Speculation. For the first time, practical on-chain activity is being driven by users in developing nations who *need* crypto, while speculation is led by those in developed nations who *want* it. The next bull run will be driven by products that bridge this divide.
  3. The Bottleneck is No Longer Technology. With scalability largely solved (blockchains now process over 3,400 TPS), the primary barriers to adoption have shifted from infrastructure to product design, user experience, and regulatory clarity.
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October 22, 2025

MegaETH Co-Founder: How We Rebuilt Ethereum From the Ground Up

The DCo Podcast

Crypto
Key Takeaways:
  1. Question Sacred Cows: The path to breakthrough performance lies in challenging foundational assumptions. For Layer 2s, this means recognizing that sequencer decentralization may be a solution in search of a problem.
  2. Focus and Outsource: MegaETH’s strategy is simple: be the best at performance by outsourcing the hardest part—consensus—to Ethereum. This allows them to build a hyper-optimized execution environment without compromising on security.
  3. Hire Outside the Echo Chamber: The next major blockchain innovation may not come from a crypto veteran. Expertise from adjacent fields like low-latency computing can provide the first-principles thinking needed to solve the industry’s most entrenched problems.
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October 22, 2025

Institutional Demand for Crypto is Accelerating | Matt Hougan

Forward Guidance

Crypto
Key Takeaways:
  1. **Allocations Are Multiplying:** The standard institutional crypto allocation is moving from a timid 1% to a more confident 3-5%, driven by crypto's declining volatility and the fading fear of a "go-to-zero" event.
  2. **The ETF Universe is Exploding:** New SEC guidelines will unleash a wave of crypto ETFs, from single assets to index funds. This will reshape market structure and provide traditional investors with simple on-ramps to the entire ecosystem.
  3. **Stablecoins are the Real Trojan Horse:** Beyond Bitcoin, institutional demand for stablecoins is immense. They aren't just an asset; they are recognized as the critical settlement layer for a tokenized, 24/7 global market.
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October 21, 2025

Inside Coinbase’s $375m Acquisition of Echo | Shan Aggarwal

Empire

Crypto
Key Takeaways:
  1. Becoming the Capital Stack: Coinbase's endgame is not just being a crypto exchange but providing the full, end-to-end infrastructure for any company—crypto or traditional—to issue, manage, and raise capital on-chain.
  2. Acquire Missionaries, Not Mercenaries: Their M&A success hinges on a proactive, culture-first approach. They identify strategic needs, hunt for the best teams, and integrate them deeply, ensuring founders stay long after their earnouts expire.
  3. Prediction Markets are the Next Trojan Horse: Coinbase is betting big on prediction markets to onboard the next wave of mainstream users, using familiar activities like sports betting as an accessible entry point into the crypto ecosystem.
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October 21, 2025

What's Happening to Crypto Markets? The Onchain Data That Explains Everything

Bankless

Crypto
Key Takeaways:
  1. Leverage Overload, Fundamental Weakness. Record leverage created a "house of cards" structure. Without strong underlying spot volume and new buyers, the market became highly susceptible to cascading liquidations.
  2. The Profits Are In. Long-term Bitcoin holders have already cashed out nearly twice the profit they did last cycle ($900B vs. $500B), indicating the "wealth distribution" phase is well underway.
  3. The Line in the Sand. The key level to watch is Bitcoin's 50-week moving average (around $102k). As long as Bitcoin holds above it, the bull market structure remains intact; two weekly closes below it would be a strong confirmation that the cycle is over.
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