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AI Podcasts

December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The AI era will disproportionately reward existing businesses that deeply integrate AI to create unassailable cost structures, not just new AI-native ventures.
  2. Builder/Investor Note: Seek out resilient "Act II" leaders who embrace the "and" business—growth, innovation, and profitability—and are willing to navigate public market scrutiny for long-term alignment.
  3. The "So What?": Over the next 6-12 months, expect market volatility to create opportunities to invest in disciplined companies leveraging AI for fundamental operational shifts, rather than just hype.
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December 15, 2025

The Renaissance of the American Factory | a16z 2026 Big Ideas

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next wave of industrial growth will come from applying manufacturing principles to large-scale infrastructure, not just consumer goods.
  2. Builder/Investor Note: Focus on companies that are standardizing designs and processes for physical assets, particularly those leveraging AI to navigate regulatory complexity and accelerate deployment.
  3. The "So What?": The rapid build-out of data centers is a live experiment for a broader industrial renaissance, providing a blueprint for how America can rebuild its capacity to build at scale over the next 6-12 months.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Implication: The "AI safety" narrative is shifting from content moderation to systemic security. Focus on hardening the entire AI ecosystem, not just restricting model outputs.
  2. Builder/Investor Note: Be wary of "AI security" products that claim to "secure the model" through guardrails. These are likely security theater. Invest in full-stack AI security solutions, red teaming services, and platforms that facilitate open-source adversarial research.
  3. The "So What?": The future of AI security is not about building higher walls around models, but about understanding and hardening the entire ecosystem in which they operate. Open collaboration and adversarial testing are the fastest paths to robust AI.
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December 15, 2025

Evolving Large Language Model Evaluation: Practices and Insights from the Swallow Project

Weights & Biases

AI
Key Takeaways:
  1. Strategic Implication: The quality and sophistication of LLM evaluation frameworks are now as critical as the models themselves. This is a foundational layer for AI progress.
  2. Builder/Investor Note: Builders must adopt adaptive evaluation. Investors should scrutinize how LLM performance is measured, not just the headline numbers.
  3. The "So What?": As LLMs gain complex reasoning and instruction-following abilities, evaluation frameworks that can accurately measure these capabilities will be essential for identifying true innovation and avoiding misallocated resources in the next 6-12 months.
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December 15, 2025

LLM Research and Development Initiatives at the National Institute of Informatics

Weights & Biases

AI
Key Takeaways:
  1. Sovereign AI is Real: Nations are investing in domestic AI capabilities to counter linguistic bias and ensure data control. This creates opportunities for specialized models and infrastructure.
  2. Builder's Edge: Meticulous parameter tuning, high-quality data curation, and innovative architectures like MoE are crucial for achieving top-tier LLM performance.
  3. The Agentic Future: AI agents are rapidly becoming indispensable tools in research and education, demanding robust, reliable, and culturally relevant LLM backbones.
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December 15, 2025

Coding Evals: From Code Snippets to Codebases – Naman Jain, Cursor

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: The future of AI code generation hinges on dynamic, robust evaluation systems that adapt to evolving model capabilities and detect sophisticated exploitation.
  2. Builder/Investor Note: Invest in or build evaluation infrastructure that incorporates dynamic problem sets, LLM-driven hack detection, and granular, human-centric metrics.
  3. The "So What?": Relying on static benchmarks is a losing game. The next 6-12 months will see a push towards more sophisticated, real-world-aligned evaluation methods, separating genuinely capable models from those that merely game the system.
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December 15, 2025

Building in the Gemini Era – Kat Kampf & Ammaar Reshi, Google DeepMind

AI Engineer

AI
Key Takeaways:
  1. Intent Over Implementation: The value in software creation shifts from low-level coding to clearly defining intent and design, with AI handling the technical execution.
  2. Rapid Prototyping: Builders can now rapidly prototype and deploy complex, full-stack applications, significantly compressing development cycles and lowering entry barriers.
  3. New Creator Economy: Expect a surge in non-technical creators building sophisticated applications, driving innovation in UI/UX and personalized content.
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December 15, 2025

The Renaissance of the American Factory | a16z 2026 Big Ideas

a16z

AI
Key Takeaways:
  1. Strategic Shift: The "factory-first" mindset is a strategic reorientation towards physical production, enabled by AI, extending beyond traditional manufacturing to all large-scale infrastructure.
  2. Builder/Investor Note: Focus on companies applying modular design, AI-driven process optimization, and automation to sectors like housing, energy, and mining. Data centers are a leading indicator for these trends.
  3. The "So What?": Rebuilding America's industrial capacity through these methods offers a competitive advantage, impacting defense, consumer goods, and commercial sectors in the next 6-12 months.
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December 13, 2025

Minimax M2 – Olive Song, MiniMax

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: The future of AI agents hinges on practical utility and adaptive reasoning, not just raw scale. Models that integrate expert feedback and iterative thinking will outperform those focused solely on benchmarks.
  2. Builder/Investor Note: Builders should prioritize robust generalization through diverse training perturbations. Investors should seek models that demonstrate real-world adoption and cost-effective scalability for multi-agent architectures.
  3. The So What?: The next 6-12 months will see a shift towards smaller, highly specialized, and deeply integrated AI models that function as reliable co-workers, driving efficiency in developer workflows and complex agentic tasks.
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Crypto Podcasts

November 5, 2025

Quadrillions: Unlocking Quadrillions | Don Wilson & Yuval Rooz

Empire

Crypto
Key Takeaways:
  1. **Privacy Isn't a Feature; It's the Foundation.** For institutions, confidentiality is non-negotiable. Any network aiming to attract serious capital must offer privacy that allows for compliance without broadcasting every move to the world.
  2. **Real Adoption Is a Long Game.** Chasing bull market hype is a losing strategy for enterprise adoption. Canton’s success with partners like Goldman Sachs, DTCC, and Citadel demonstrates the power of prioritizing utility and compliance over a premature token launch.
  3. **The Next Wave Is Tokenizing Everything.** The goal is to move beyond crypto-native assets. The real prize is upgrading the rails for the world's existing financial system—equities, bonds, and treasuries—by making them digitally native, 24/7, and instantly settleable.
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November 5, 2025

The Next Chapter For Blockworks | Empire

Forward Guidance

Crypto
Key Takeaways:
  1. Focus or Fade. As the industry matures, companies must shed non-core business units to become world-class at one thing. For Blockworks, that's data, not news.
  2. Buy the Theme. Public market investors will pay a massive premium for the only stock representing a major crypto trend (e.g., Securitize for tokenization), often making it a better trade than trying to pick winners among underlying assets.
  3. Growth is Subsidized. Major L1/L2 foundations are actively paying for enterprise adoption (e.g., Solana and Western Union). This is a standard business practice to kickstart network effects, but the long-term ROI remains unproven.
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November 5, 2025

fomo: Paul and Se

Archetype

Crypto
Key Takeaways:
  1. Social Proof is the New Alpha. FOMO’s core bet is that transparently tracking successful wallets is a more powerful discovery mechanism than traditional research. By making on-chain activity legible and social, it unlocks a new paradigm for retail investing.
  2. User Experience Wins the Next Cycle. The next 100 million crypto users will not be onboarded with seed phrases and gas fees. By abstracting away all technical friction and mirroring the seamlessness of Web2 apps, FOMO provides a blueprint for mass adoption.
  3. Trading is Becoming a Spectator Sport. By turning trading performance into a form of content, FOMO is building a new financial creator economy. The best traders are the new influencers, and their alpha is the content that drives the entire ecosystem.
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November 5, 2025

x402: The Key to Internet Money, Micropayments & The AI Agent Economy

Bankless

Crypto
Key Takeaways:
  1. The Internet Gets Its Native Wallet. x402 uses crypto to finally fulfill the internet's original vision of direct, peer-to-server payments, unlocking an economy of micropayments for everything from accessing an article to running an AI model.
  2. The Ad-Supported Web Is Obsolete. AI agents that retrieve information without viewing ads are killing the web's 20-year-old business model. x402 provides the new economic rails for a pay-per-use internet where value is exchanged for resources, not attention.
  3. Build Composable Money Legos. The biggest opportunity lies in creating simple, single-purpose APIs that agents can easily discover and compose. Think of it as building for the App Store of the emerging AI agent economy.
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November 5, 2025

Why the Crypto Markets Seem Down Bad as Bitcoin Dips Below $100K

Unchained

Crypto
Key Takeaways:
  1. Despite the brutal sentiment, both speakers remain bullish, predicting a sharp reversal and a new all-time high for Bitcoin by the end of the year once macro clarity emerges.
  2. Macro is King. Bitcoin's fate is now tied to the broader economy. Forget four-year cycles; the key catalyst is a resolution to the government shutdown, which could unlock pent-up energy in the market.
  3. The Treasury Trade is Toast. The era of companies boosting their stock by simply buying Bitcoin is over. Expect a painful shakeout as the market demands real utility and revenue, leading to more forced selling.
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November 5, 2025

Play to Earn Crypto Games: $65B Opportunity | Open Game Protocol & Zynga Founder

The DCo Podcast

Crypto
Key Takeaways:
  1. Distribution is the prize, not payments. The real money in gaming isn't in payment rails, which are being competed down to zero. The scarcest and most valuable asset is user attention, and Open Game Protocol is designed to monetize distribution.
  2. Decouple to survive. Tying a single game to a single token creates a fatal dependency. A flexible, many-to-many protocol allows ecosystems to thrive by spreading risk and aligning incentives across multiple games and communities.
  3. Content abundance requires new discovery. As AI makes game creation cheap and fast, the bottleneck shifts from production to discovery. Integrating games directly into high-intent surfaces like crypto wallets creates a powerful, non-advertising-based discovery channel.
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