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AI Podcasts

May 29, 2025

Beyond Leaderboards: LMArena’s Mission to Make AI Reliable

a16z

AI
Key Takeaways:
  1. Reliability Demands Real-Time, Human-Centric Testing: Static benchmarks are dead. AI reliability for complex tasks requires continuous evaluation based on diverse, subjective human preferences in real-world scenarios.
  2. Crowd-Sourced Evaluation Outperforms Insular Expertise: The "wisdom of the crowd," as captured by LMArena, provides a more robust and representative measure of AI performance than siloed expert opinions, preventing narrow value-encoding.
  3. Personalized Evaluation is the Next Frontier: Technologies like "Prompt to Leaderboard" show the potential for highly granular, cost-effective, and personalized AI model selection, maximizing utility for individual users and specific tasks.
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May 28, 2025

Rick Rubin: Vibe Coding is the Punk Rock of Software

a16z

AI
Key Takeaways:
  1. Embrace AI as a Co-Creator: Leverage AI to democratize creation and rapidly iterate, but remember the unique human element—your distinct point of view and intuition—is irreplaceable.
  2. Authenticity Over Algorithm: Whether you're an artist or an entrepreneur, genuine connection comes from unwavering commitment to your core vision, not by chasing fleeting trends or assumed audience desires.
  3. Question Everything, Especially "Answers": Cultivate a mindset of curiosity and critical thinking. AI can provide answers, but true insight comes from deeply engaging with questions and understanding that knowledge is ever-evolving.
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May 27, 2025

7 More Healthy Years: What We Can Learn from Super Agers

a16z

AI
Key Takeaways:
  1. Embrace AI-Powered Prevention: AI's capacity to synthesize vast health data will redefine personalized risk assessment and early intervention, moving us beyond one-size-fits-all healthcare.
  2. Target the "Big Three" Early: Focus on preventing cancer, cardiovascular disease, and neurodegenerative conditions by leveraging their long incubation periods for proactive interventions.
  3. Leverage New Therapeutic Frontiers: Groundbreaking drug classes like GLP-1s and rapid advancements in immunotherapy offer unprecedented tools to combat and, crucially, prevent major diseases.
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May 27, 2025

TAOFU's Mikel & Mitch: Enabling Capital Formation for Subnets on Bittensors $10B+ Network

Delphi Digital

AI
Key Takeaways:
  1. Democratized Subnet Funding: TAOFU’s SNS model allows subnet creators to raise capital without diluting their core emission-earning potential, fostering more shots on goal for AI innovation on Bittensor.
  2. Investor Access & Liquidity: For investors, TAOFU provides a clear mechanism (SNS tokens and an integrated DEX) to invest in early-stage Bittensor subnets and gain liquidity, previously a closed-off and opaque process.
  3. Curated Quality: TAOFU’s permissioned approach and focus on sustainable value capture (with plans for a curator model) aim to filter for high-quality projects, protecting investors while nurturing promising AI ventures within Bittensor.
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May 26, 2025

Has AI Revived the DePIN Sector? | Dmitriy Berenzon

0xResearch

AI
Key Takeaways:
  1. AI is DePIN's Demand Catalyst: The need for affordable AI compute is breathing new life and tangible demand into decentralized infrastructure.
  2. Value Accrual & Revenue are King: For DePIN tokens to thrive in liquid markets, clear mechanisms for value flow-through from opco revenue to the token are non-negotiable; "ARR is the new TVL."
  3. Distribution Trumps Decentralization (for now): Crypto-native solutions, especially in payments, must crack the distribution code or risk being outmaneuvered by Web2 incumbents leveraging their massive user bases.
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May 26, 2025

Chatbot platforms might replace social media

Machine Learning Street Talk

AI
Key Takeaways:
  1. AI Companionship is Exploding: Millions are already deeply engaged with AI for emotional connection, and this is just the beginning as technology like GPT-4o normalizes it.
  2. Lean Engineering Can Win: Chai's success with a tiny, hyper-talented team and innovative techniques like model blending proves that massive VC-backed operations aren't the only path to scale in AI.
  3. The Next Social Platform Might Be AI: As AI offers more active, personalized, and consequence-free social interaction, it could very well become the dominant way people connect, potentially supplanting traditional social media.
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May 25, 2025

How Endless Debt Became America's Culture

Forward Guidance

AI
Key Takeaways:
  1. **Debt is Destiny:** America's fiscal irresponsibility and cultural embrace of debt ensure ongoing money printing and inflation, making currency debasement a near certainty.
  2. **The One True Trade:** Forget complex analytics; the primary goal is preserving purchasing power. This means owning store-of-value assets like Bitcoin and gold, which are positioned to thrive.
  3. **AI Accelerates the Crisis:** Artificial intelligence will not only disrupt labor markets but also intensify the debt crisis by devaluing traditional education and fueling calls for more government relief.
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May 24, 2025

SN85 :: VIDAIO :: Decentralized AI Video Upscaling & Compression ++ Roadmap & Enterprise Utility

Opentensor Foundation

AI
Key Takeaways:
  1. Decentralized AI is Production-Ready: VIDAIO demonstrates that complex AI tasks like video processing can be effectively decentralized and optimized through BitTensor's subnet model, with miners already outperforming base models.
  2. Perceptual Quality Wins: Focusing on human-perceived video quality, rather than just raw specs, is key for AI video tools, leading to more efficient and visually appealing results.
  3. Subnets Must Aim for Self-Sufficiency: The long-term viability of BitTensor subnets hinges on generating real-world revenue and solving actual customer problems, moving beyond reliance on token emissions.
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May 24, 2025

Sovereign AI: Why Nations Are Building Their Own Models

a16z

AI
Key Takeaways:
  1. National AI is Non-Negotiable: Countries are investing heavily in "AI factories" to control their digital destiny and cultural narratives.
  2. Models are Culture: AI outputs reflect embedded values, making local control over AI development and deployment a geopolitical imperative.
  3. Lead by Building Better: The US can maintain AI leadership by out-innovating competitors and enabling allies, pursuing "foundation model diplomacy" to ensure its technology underpins global progress.
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Crypto Podcasts

July 17, 2025

Why $1 Of Bitcoin Held By A Public Company Is Worth More Than $1

Empire

Crypto
Key Takeaways:
  1. Active Value Creation Over Passive Holding: The primary investment thesis is not just owning Bitcoin, but owning a company that actively works to increase your proportional stake in Bitcoin through astute capital management.
  2. Shareholders Benefit from Arbitrage: The company can issue stock at a premium to buy more assets or sell assets to buy back stock at a discount, with both actions increasing the crypto-per-share metric for existing holders.
  3. A Structurally Superior Model: This model aligns management and shareholder interests to grow NAV per share, a dynamic missing from both passive ETFs (where third parties capture arbitrage) and older closed-end funds (which suffered from principal-agent issues).
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July 17, 2025

10 Bullish ETH Charts

Bankless

Crypto
Key Takeaways:
  1. The Institutional Bid is Real and Diversified. Institutions are not just buying ETH via ETFs; they are building with it via stablecoins, tokenizing real-world assets on it, and holding it directly in corporate treasuries.
  2. ETH's Supply Dynamics are a Ticking Time Bomb. With issuance lower than Bitcoin, an 8-year low of supply on exchanges, and over 43% of ETH locked in smart contracts, a powerful supply shock is building beneath the surface.
  3. L2s are a Feature, Not a Bug. The temporary hit to L1 revenue is a calculated investment in mass adoption. By fostering a thriving Layer 2 ecosystem, Ethereum is sacrificing short-term fees for long-term network dominance and pricing power.
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July 16, 2025

PUMP Buybacks Initialized

0xResearch

Crypto
Key Takeaways:
  1. PUMP is the New Memecoin Index: The market is treating PUMP as a direct proxy for the health of the entire memecoin ecosystem. Its performance is a leveraged bet on speculative activity, making it a crucial asset to watch.
  2. On-Chain Venues Are Winning: The PUMP launch was a massive fumble for centralized exchanges and a huge win for on-chain infrastructure like Solana and Hyperliquid, which handled record volume smoothly. Price discovery now happens on-chain first.
  3. The Frontend is the Next Battlefield: PUMP’s biggest challenge is not just competitors like Bonk.fun, but the risk of being disintermediated by trading apps. To survive, it must become a destination platform, not just backend infrastructure.
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July 16, 2025

Bitcoin Moons, Can Banks Win Stablecoins & Will ICOs Boom? Bits + Bips

Unchained

Crypto
Key Takeaways:
  1. Big Banks Are The Stablecoin Play. Forget fintech disruption; the Genius Act positions traditional banks with massive balance sheets and collateral access as the primary beneficiaries of the stablecoin boom, not Silicon Valley.
  2. Bitcoin Miners Are a Leading Indicator. The performance of publicly traded Bitcoin miners often precedes major moves in Bitcoin's price, making them a "canary in the coal mine" for traders seeking an edge.
  3. Real-World Assets Demand New Blockchains. The future of tokenized assets won't happen on today's chains. The winners will be platforms like Stellar or Avalanche Subnets that offer validator-level controls for transaction reversal, sacrificing permissionlessness for institutional-grade security.
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July 15, 2025

ETH Earnings Report Q2 2025

Bankless

Crypto
Key Takeaways:
  1. **Stimulus Over-Revenue:** The Petra upgrade was an intentional move to prioritize L2 user growth over immediate L1 fee generation. Investors should view L1 metrics through this lens—low fees are currently a feature, not a bug.
  2. **The Great Rotation:** ETH is migrating from exchanges to more permanent homes like ETFs, corporate treasuries, and staking contracts. This institutional embrace is solidifying ETH's store-of-value thesis, even as its "productive asset" yield fluctuates.
  3. **DeFi's Pulse is Strong:** Don't mistake lower L1 fees for a weak economy. With active loans at an all-time high, the demand to use ETH and other assets within its DeFi ecosystem is stronger than ever.
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July 15, 2025

Empire Cross-Post: The Crypto Treasury Playbook With Ben Forman & Josh Solesbury From ParaFi Capital

Bell Curve

Crypto
Key Takeaways:
  1. The Playbook is the Product. These vehicles are not passive holders. Their value comes from financial engineering—actively arbitraging their own stock premium/discount to accumulate more crypto per share, a dynamic ETFs lack.
  2. Saturation Will Lead to Consolidation. The market is becoming crowded with copycats. Expect a shakeout where many vehicles trade at a discount, leading to a wave of M&A as weaker players are absorbed by stronger ones.
  3. The Next Domino is Corporate America. Public companies and ETFs now own 10% of all Bitcoin. The next major catalyst is a non-crypto-native, Fortune 500 company allocating treasury reserves to Bitcoin, a move the speakers believe could happen within 12 months.
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