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AI Podcasts

December 16, 2025

Why Physical AI Needs a new Data Set | Rerun CEO

Weights & Biases

AI
Key Takeaways:
  1. Data Infrastructure is the Next Bottleneck: The physical AI sector's growth hinges on specialized data tooling that can handle multimodal, multi-rate, episodic data, moving beyond traditional tabular models.
  2. Builders, Prioritize Robustness: Focus on building systems that handle real-world variability and simplify data pipelines. Leverage open-source tools and consider combining imitation and reinforcement learning.
  3. The "So What?": The next 6-12 months will see significant improvements in robot robustness and the ability to perform longer, more complex tasks. This progress will be driven by better data management, making the gap between lab demos and deployable products narrower.
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December 16, 2025

Build reliable AI agents using W&B Training

Weights & Biases

AI
Key Takeaways:
  1. The democratization of RL for LLMs will accelerate the deployment of more reliable and sophisticated AI agents across industries.
  2. Builders should move beyond basic prompt engineering and RAG. RL fine-tuning, now accessible via W&B Serverless RL, is a critical next step for high-stakes agentic applications.
  3. For the next 6-12 months, expect a surge in production-grade AI agents, with open-source models increasingly closing the performance gap with proprietary alternatives through advanced fine-tuning.
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December 15, 2025

Coding Evals: From Code Snippets to Codebases – Naman Jain, Cursor

AI Engineer

AI
Key Takeaways:
  1. Dynamic Evaluation is Non-Negotiable: Static benchmarks are dead. Future AI development demands continuously updated, contamination-resistant evaluation sets.
  2. AI Needs AI to Judge AI: As models grow more sophisticated, LLM-driven "hack detectors" become essential for ensuring code quality and preventing adversarial exploitation of evaluation systems.
  3. User Experience Drives Adoption: For interactive AI coding tools, prioritize low latency and human-centric design; technical prowess alone will not guarantee real-world usage.
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December 15, 2025

Building in the Gemini Era – Kat Kampf & Ammaar Reshi, Google DeepMind

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: The value in software development shifts from manual coding to high-level architectural design and prompt engineering.
  2. Builder/Investor Note: Experiment with AI Studio's agentic and design capabilities. Focus on describing desired functionality rather than low-level code.
  3. The "So What?": The next 6-12 months will see a surge in AI-powered, full-stack applications built by a broader range of creators, disrupting traditional development paradigms.
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December 16, 2025

What We Learned Deploying AI within Bloomberg’s Engineering Organization – Lei Zhang, Bloomberg

AI Engineer

AI
Key Takeaways:
  1. Strategic Shift: AI's impact extends beyond simple productivity. The real opportunity lies in fundamentally changing the cost function of engineering, making previously expensive or undesirable tasks cheap and feasible.
  2. Platform Imperative: For large organizations, a "golden path" platform is not optional. It's how you manage complexity, ensure quality, and scale AI adoption safely and efficiently.
  3. Human-Centric Adaptation: Technology is only half the battle. Investing in cultural adaptation, community building, and leadership training is crucial for realizing AI's full potential.
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December 16, 2025

Your Support Team Should Ship Code – Lisa Orr, Zapier

AI Engineer

AI
Key Takeaways:
  1. Strategic Implication: Companies integrating AI-driven code generation into non-engineering roles will see significant efficiency gains and improved product reliability.
  2. Builder/Investor Note: Focus on building AI tools that deeply embed into existing workflows. Orchestration of multiple AI tools into an agent-like system is key for adoption and value.
  3. The "So What?": The next 6-12 months will see a redefinition of "support" from reactive reporting to proactive, code-shipping problem-solving, unlocking new talent pools and accelerating development cycles.
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December 16, 2025

Finding The 1% of Stocks That Matter | Henry Ellenbogen Interview

Invest Like The Best

AI
Key Takeaways:
  1. Strategic Implication: The AI era will disproportionately reward existing businesses that deeply integrate AI to create unassailable cost structures, not just new AI-native ventures.
  2. Builder/Investor Note: Seek out resilient "Act II" leaders who embrace the "and" business—growth, innovation, and profitability—and are willing to navigate public market scrutiny for long-term alignment.
  3. The "So What?": Over the next 6-12 months, expect market volatility to create opportunities to invest in disciplined companies leveraging AI for fundamental operational shifts, rather than just hype.
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December 15, 2025

The Renaissance of the American Factory | a16z 2026 Big Ideas

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next wave of industrial growth will come from applying manufacturing principles to large-scale infrastructure, not just consumer goods.
  2. Builder/Investor Note: Focus on companies that are standardizing designs and processes for physical assets, particularly those leveraging AI to navigate regulatory complexity and accelerate deployment.
  3. The "So What?": The rapid build-out of data centers is a live experiment for a broader industrial renaissance, providing a blueprint for how America can rebuild its capacity to build at scale over the next 6-12 months.
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December 16, 2025

⚡️Jailbreaking AGI: Pliny the Liberator & John V on Red Teaming, BT6, and the Future of AI Security

Latent Space

AI
Key Takeaways:
  1. Strategic Implication: The "AI safety" narrative is shifting from content moderation to systemic security. Focus on hardening the entire AI ecosystem, not just restricting model outputs.
  2. Builder/Investor Note: Be wary of "AI security" products that claim to "secure the model" through guardrails. These are likely security theater. Invest in full-stack AI security solutions, red teaming services, and platforms that facilitate open-source adversarial research.
  3. The "So What?": The future of AI security is not about building higher walls around models, but about understanding and hardening the entire ecosystem in which they operate. Open collaboration and adversarial testing are the fastest paths to robust AI.
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Crypto Podcasts

November 5, 2025

Quadrillions: Unlocking Quadrillions | Don Wilson & Yuval Rooz

Empire

Crypto
Key Takeaways:
  1. **Privacy Isn't a Feature; It's the Foundation.** For institutions, confidentiality is non-negotiable. Any network aiming to attract serious capital must offer privacy that allows for compliance without broadcasting every move to the world.
  2. **Real Adoption Is a Long Game.** Chasing bull market hype is a losing strategy for enterprise adoption. Canton’s success with partners like Goldman Sachs, DTCC, and Citadel demonstrates the power of prioritizing utility and compliance over a premature token launch.
  3. **The Next Wave Is Tokenizing Everything.** The goal is to move beyond crypto-native assets. The real prize is upgrading the rails for the world's existing financial system—equities, bonds, and treasuries—by making them digitally native, 24/7, and instantly settleable.
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November 5, 2025

The Next Chapter For Blockworks | Empire

Forward Guidance

Crypto
Key Takeaways:
  1. Focus or Fade. As the industry matures, companies must shed non-core business units to become world-class at one thing. For Blockworks, that's data, not news.
  2. Buy the Theme. Public market investors will pay a massive premium for the only stock representing a major crypto trend (e.g., Securitize for tokenization), often making it a better trade than trying to pick winners among underlying assets.
  3. Growth is Subsidized. Major L1/L2 foundations are actively paying for enterprise adoption (e.g., Solana and Western Union). This is a standard business practice to kickstart network effects, but the long-term ROI remains unproven.
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November 5, 2025

fomo: Paul and Se

Archetype

Crypto
Key Takeaways:
  1. Social Proof is the New Alpha. FOMO’s core bet is that transparently tracking successful wallets is a more powerful discovery mechanism than traditional research. By making on-chain activity legible and social, it unlocks a new paradigm for retail investing.
  2. User Experience Wins the Next Cycle. The next 100 million crypto users will not be onboarded with seed phrases and gas fees. By abstracting away all technical friction and mirroring the seamlessness of Web2 apps, FOMO provides a blueprint for mass adoption.
  3. Trading is Becoming a Spectator Sport. By turning trading performance into a form of content, FOMO is building a new financial creator economy. The best traders are the new influencers, and their alpha is the content that drives the entire ecosystem.
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November 5, 2025

x402: The Key to Internet Money, Micropayments & The AI Agent Economy

Bankless

Crypto
Key Takeaways:
  1. The Internet Gets Its Native Wallet. x402 uses crypto to finally fulfill the internet's original vision of direct, peer-to-server payments, unlocking an economy of micropayments for everything from accessing an article to running an AI model.
  2. The Ad-Supported Web Is Obsolete. AI agents that retrieve information without viewing ads are killing the web's 20-year-old business model. x402 provides the new economic rails for a pay-per-use internet where value is exchanged for resources, not attention.
  3. Build Composable Money Legos. The biggest opportunity lies in creating simple, single-purpose APIs that agents can easily discover and compose. Think of it as building for the App Store of the emerging AI agent economy.
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November 5, 2025

Why the Crypto Markets Seem Down Bad as Bitcoin Dips Below $100K

Unchained

Crypto
Key Takeaways:
  1. Despite the brutal sentiment, both speakers remain bullish, predicting a sharp reversal and a new all-time high for Bitcoin by the end of the year once macro clarity emerges.
  2. Macro is King. Bitcoin's fate is now tied to the broader economy. Forget four-year cycles; the key catalyst is a resolution to the government shutdown, which could unlock pent-up energy in the market.
  3. The Treasury Trade is Toast. The era of companies boosting their stock by simply buying Bitcoin is over. Expect a painful shakeout as the market demands real utility and revenue, leading to more forced selling.
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November 5, 2025

Play to Earn Crypto Games: $65B Opportunity | Open Game Protocol & Zynga Founder

The DCo Podcast

Crypto
Key Takeaways:
  1. Distribution is the prize, not payments. The real money in gaming isn't in payment rails, which are being competed down to zero. The scarcest and most valuable asset is user attention, and Open Game Protocol is designed to monetize distribution.
  2. Decouple to survive. Tying a single game to a single token creates a fatal dependency. A flexible, many-to-many protocol allows ecosystems to thrive by spreading risk and aligning incentives across multiple games and communities.
  3. Content abundance requires new discovery. As AI makes game creation cheap and fast, the bottleneck shifts from production to discovery. Integrating games directly into high-intent surfaces like crypto wallets creates a powerful, non-advertising-based discovery channel.
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