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AI Podcasts

January 15, 2026

Ben & Marc: Why Everything Is About to Get 10x Bigger

a16z

AI
Key Takeaways:
  1. The transition from software eating the world to AI reinventing the computer means every existing market cap is a floor.
  2. Prioritize the non-fungible creator by providing monetization tools that bypass legacy gatekeepers.
  3. We are entering a period of asymmetric payoffs where the art of picking original thinkers matters more than historical data.
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January 13, 2026

Paul Rosolie: Uncontacted Tribes in the Amazon Jungle | Lex Fridman Podcast #489

Lex Fridman

AI
Key Takeaways:
  1. The Macro Trend: Biological Sovereignty. As global systems destabilize, the Amazon remains the most critical piece of biological infrastructure on the planet.
  2. The Tactical Edge: Support Jungle Keepers. Direct capital to organizations that convert loggers into rangers to secure land concessions.
  3. The Amazon is a finite asset under active siege. Protecting it requires a blend of primitive survival skills and high-tech surveillance over the next 18 months.
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January 12, 2026

Jensen Huang says robots will have human capabilities this year! The Robots at CES Had.. Other Plans

Turing Post

AI
Key Takeaways:
  1. The Macro Pivot: As generative AI masters simulation, the physical world becomes a high-fidelity playground for software.
  2. The Tactical Edge: Invest in the "brain" layer rather than the "limb" layer. Software that can generalize across different hardware forms will capture the most value.
  3. The next decade belongs to embodied AI that reasons in real time. If you are waiting for the hardware to look perfect before paying attention, you will miss the moment the software takes over the physical world.
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January 12, 2026

Your MCP Server is Bad (and you should feel bad) - Jeremiah Lowin, Prefect

AI Engineer

AI
Key Takeaways:
  1. The Macro Pivot: Context as Product. We are moving from raw data transport to opinionated context delivery.
  2. The Tactical Edge: Prune your endpoints. Remove any tool that requires more than one step to achieve a business result.
  3. The Bottom Line: The winners of the agentic era will be those who build the best Agentic Interface Guidelines.
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January 12, 2026

OpenAI + @Temporalio : Building Durable, Production Ready Agents - Cornelia Davis, Temporal

AI Engineer

AI
Key Takeaways:
  1. The industry is moving from "Agent as a Script" to "Agent as a Durable Service" where state management is handled by the infrastructure.
  2. Wrap your existing API tools in the `activity_as_tool` function to gain automatic retries and execution history.
  3. Reliability is the only moat in the agentic economy. If your agent cannot survive a server restart during a three-day task, it is not ready for the enterprise.
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January 13, 2026

How Ladder Became #1 Strength Training App

Invest Like The Best

AI
Key Takeaways:
  1. The Macro Trend: The move from fragmented content libraries to integrated health systems where AI synthesizes biomarkers and movement.
  2. The Tactical Edge: Construct internal LLM tools to categorize qualitative feedback. This turns thousands of raw reviews into a precise roadmap.
  3. The Bottom Line: Building a $100M ARR consumer app requires mastery of both growth loops and product retention. Solve for the daily habit to win the long game.
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January 13, 2026

Ben Horowitz on Investing in AI: AI Bubbles, Economic Impact, and VC Acceleration

a16z

AI
Key Takeaways:
  1. The transition from general-purpose AI to specialized application layers. As foundation models commoditize, value migrates to the "fat tail" of human-centric complexity.
  2. Prioritize building or investing in "DNA of the future" companies that incumbents must eventually acquire to survive. Focus on winning the "point of attack" by staying deep in the technical details.
  3. We are in a unique market where demand growth justifies high valuations. Success over the next year depends on identifying founders who are the absolute best in the world at one specific thing.
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January 13, 2026

It's Time To Build

a16z

AI
Key Takeaways:
  1. The Macro Shift: Infrastructure Invisibility. As core technologies become background noise, value moves from the pipes to the unique experiences built on top of them.
  2. The Tactical Edge: Reject Mediocrity. Audit your product for average features and replace them with high-conviction improvements that competitors are too lazy to attempt.
  3. The Bottom Line: Building is the only way to ensure the future happens. If you do not create the next version of reality, you are stuck living in an outdated vision.
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January 13, 2026

Nothing’s Carl Pei on Building a $1B Smartphone Company and Why He Thinks About Death Every Week

The Generalist

AI
Key Takeaways:
  1. The transition from hardware specs to emotional hardware where brand identity and OS-native AI become the primary moats.
  2. Prioritize arbitrage opportunities in marketing by finding underpriced attention on platforms like TikTok before they become crowded.
  3. Success in mature markets requires a Genghis Khan method: be a talent scout, stay open-minded to global supply chains, and use design to win the emotional battle for the consumer's pocket.
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Crypto Podcasts

December 2, 2025

Crypto Dumps on BOJ Pivot Signal as Tether, Strategy Turmoil Hit Markets: Bits + Bips

Unchained

Crypto
Key Takeaways:
  1. Macro is Back in Charge. The era of cheap leverage is facing a global reckoning, with the unwind of the Yen Carry Trade serving as a key trigger. High-beta assets like crypto are the first to feel the pain.
  2. Narrative Trumps Numbers. MicroStrategy's dip wasn't about math; it was about breaking a story. In crypto, violating a core community belief can be more damaging than a weak earnings report.
  3. TradFi's Fragility is Crypto's Calling Card. While crypto fends off FUD, a major institution like the CME went offline for 10 hours due to a failed air conditioner. This is a powerful, real-world advertisement for decentralized resilience.
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December 2, 2025

Crypto Dumps on BOJ Pivot Signal as Tether, Strategy Turmoil Hit Markets: Bits + Bips

Unchained

Crypto
Key Takeaways:
  1. High-Beta is a Crowded Trade: Crypto, alongside assets like uranium and quantum stocks, is being sold off in unison as investors rotate into value stocks. In this defensive environment, expect Bitcoin to outperform altcoins.
  2. Narrative Trumps Fundamentals (For Now): MicroStrategy’s stock plunged not on a fundamental crisis but on the CEO admitting they *might* sell Bitcoin in a corner case—a direct violation of their "never sell" narrative.
  3. Don't Fight the Central Banks: The BOJ’s tightening signal was the trigger for the dump. Conversely, the Fed's expected rate cuts and potential for future dovish leadership remain the key bullish catalysts to watch.
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December 2, 2025

LIVE | CRYPTO TRENDS WITH ALANA FROM VARIANT | 0xResearch

0xResearch

Crypto
Key Takeaways:
  1. DEXes Are Winning by Default: The sheer volume of new, on-chain-only tokens is an unstoppable force driving users to DEXes. Centralized exchanges can either integrate or become irrelevant for the long tail of assets.
  2. The Real Money is in the Rails: Don't focus on who will issue the next dominant stablecoin. The biggest opportunity lies in building the interoperability infrastructure that will connect the coming flood of branded, corporate, and national stablecoins.
  3. Bitcoin's Ultimate Bull Case is Geopolitical: In a world of fragmenting currencies and rising geopolitical tensions, Bitcoin's status as a non-sovereign, politically neutral asset makes it the ultimate contender for a global reserve currency.
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December 2, 2025

LIVE | CRYPTO TRENDS WITH ALANA FROM VARIANT | 0xResearch

0xResearch

Crypto
Key Takeaways:
  1. **Memecoins Were a Trojan Horse:** The speculative frenzy was a catalyst that massively accelerated DEX adoption and forced millions of users to finally learn how to use self-custody wallets and on-chain tools.
  2. **Prepare for Thousands of Stablecoins:** Every company with deposits will likely issue its own "branded money." The next major infrastructure battle will be building the interoperability layers—the "Visa for stablecoins"—to manage this fragmented liquidity.
  3. **The Real Stablecoin Opportunity is Global:** The next frontier isn't another USD competitor, but non-USD stablecoins tied to high-yield foreign currencies, which will unlock the creation of on-chain foreign exchange (FX) markets.
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December 2, 2025

LIVE | CRYPTO TRENDS WITH ALANA FROM VARIANT | 0xResearch

0xResearch

Crypto
Key Takeaways:
  1. DEXs are Eating the World. The on-chain asset explosion has permanently shifted trading gravity. Centralized exchanges must now integrate with DeFi or risk becoming irrelevant islands.
  2. Stablecoins are the New Gift Cards. The move to "branded money" will create a fragmented landscape. The next billion-dollar opportunity is not in issuing another stablecoin, but in building the interoperability rails that make them all work together seamlessly.
  3. Distribution is the New Defensibility. As stablecoin issuance becomes commoditized, the winners will be those with massive distribution networks (like Stripe) who can embed their currency into everyday user flows.
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December 1, 2025

The Holy Grail of Crypto Privacy: Encrypted Ethereum, FHE & Living Forever

Bankless

Crypto
Key Takeaways:
  1. FHE is crypto’s HTTPS moment. Just as HTTPS made secure browsing the default, FHE is positioned to bring end-to-end encryption to all blockchain transactions, solving a fundamental flaw without forcing users to change their behavior.
  2. Privacy is coming for your wallet, not a new chain. The "holy grail" is integrating confidentiality directly into the user's existing workflow on mainnet Ethereum. Forget bridging; the future is an "incognito mode" for your current assets.
  3. Institutional demand will drive retail privacy. The need for financial institutions like JPMorgan to protect their trades on-chain is the catalyst that will finally make robust privacy tools a standard feature for everyone.
See full notes