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AI Podcasts

May 30, 2025

Novelty Search May 29, 2025

taostats

AI
Key Takeaways:
  1. Democratization Unleashed: Subnet 17 radically lowers barriers to 3D content creation, empowering indie developers and non-artists.
  2. Gaussian Splats are Hot: This representation is emerging as a key technology for fast, high-fidelity 3D AI, and Subnet 17 is at the forefront.
  3. Web2 Validation is Key: Partnerships like the Unity "verified solution" status signal BitTensor's growing real-world utility and credibility, presenting opportunities for miners and the TAO ecosystem.
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May 30, 2025

SN17 - 404GEN :: Decentralized AI generated 3D assets

Opentensor Foundation

AI
Key Takeaways:
  1. Unlocking Creative Potential: 404GEN radically lowers barriers to 3D content creation, enabling faster iteration and new forms of interactive media previously unfeasible for smaller teams or individuals.
  2. Gaussian Splats are Ascendant: This representation is emerging as a powerful alternative for 3D AI, and 404GEN is at the forefront of its practical application and tooling.
  3. BitTensor's Competitive Edge Shines: The subnet's rapid quality improvement and the innovative ELO validation system highlight BitTensor's power to incentivize and coordinate decentralized intelligence towards state-of-the-art results.
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May 30, 2025

Hey Tech, Come to Healthcare

a16z

AI
Key Takeaways:
  1. **Build for Behavior Change:** The biggest wins will come from engaging consumers and enabling sustainable health behaviors, an area where tech excels.
  2. **AI is the Leapfrog:** Healthcare can jump directly to AI-driven solutions, bypassing clunky legacy software, especially for service-oriented tasks.
  3. **The Trillion-Dollar Prize is Real:** Whether through full-stack "payvider" models or horizontal platforms, the path to becoming the world's largest company runs through transforming the consumer healthcare experience.
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May 29, 2025

Building a DePIN-powered Shazam for Media with Rumi | Niko Cunningham and Mateusz Poreda

Proof of Coverage Media

AI
Key Takeaways:
  1. **Decentralized Analytics:** Rumi’s DePIN model democratizes media intelligence, offering far richer and more granular data than traditional players like Nielsen.
  2. **Context is King:** The "Shazam for media" capability will fuel a new generation of AI agents and interactive experiences, making media deeply engaging.
  3. **Investor Signal:** The $5M pre-seed (EV3, A16Z CSX) and early traction with industry players like Tivision validate Rumi's approach and market potential.
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May 29, 2025

Beyond Leaderboards: LMArena’s Mission to Make AI Reliable

a16z

AI
Key Takeaways:
  1. Reliability Demands Real-Time, Human-Centric Testing: Static benchmarks are dead. AI reliability for complex tasks requires continuous evaluation based on diverse, subjective human preferences in real-world scenarios.
  2. Crowd-Sourced Evaluation Outperforms Insular Expertise: The "wisdom of the crowd," as captured by LMArena, provides a more robust and representative measure of AI performance than siloed expert opinions, preventing narrow value-encoding.
  3. Personalized Evaluation is the Next Frontier: Technologies like "Prompt to Leaderboard" show the potential for highly granular, cost-effective, and personalized AI model selection, maximizing utility for individual users and specific tasks.
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May 28, 2025

Rick Rubin: Vibe Coding is the Punk Rock of Software

a16z

AI
Key Takeaways:
  1. Embrace AI as a Co-Creator: Leverage AI to democratize creation and rapidly iterate, but remember the unique human element—your distinct point of view and intuition—is irreplaceable.
  2. Authenticity Over Algorithm: Whether you're an artist or an entrepreneur, genuine connection comes from unwavering commitment to your core vision, not by chasing fleeting trends or assumed audience desires.
  3. Question Everything, Especially "Answers": Cultivate a mindset of curiosity and critical thinking. AI can provide answers, but true insight comes from deeply engaging with questions and understanding that knowledge is ever-evolving.
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May 27, 2025

7 More Healthy Years: What We Can Learn from Super Agers

a16z

AI
Key Takeaways:
  1. Embrace AI-Powered Prevention: AI's capacity to synthesize vast health data will redefine personalized risk assessment and early intervention, moving us beyond one-size-fits-all healthcare.
  2. Target the "Big Three" Early: Focus on preventing cancer, cardiovascular disease, and neurodegenerative conditions by leveraging their long incubation periods for proactive interventions.
  3. Leverage New Therapeutic Frontiers: Groundbreaking drug classes like GLP-1s and rapid advancements in immunotherapy offer unprecedented tools to combat and, crucially, prevent major diseases.
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May 27, 2025

TAOFU's Mikel & Mitch: Enabling Capital Formation for Subnets on Bittensors $10B+ Network

Delphi Digital

AI
Key Takeaways:
  1. Democratized Subnet Funding: TAOFU’s SNS model allows subnet creators to raise capital without diluting their core emission-earning potential, fostering more shots on goal for AI innovation on Bittensor.
  2. Investor Access & Liquidity: For investors, TAOFU provides a clear mechanism (SNS tokens and an integrated DEX) to invest in early-stage Bittensor subnets and gain liquidity, previously a closed-off and opaque process.
  3. Curated Quality: TAOFU’s permissioned approach and focus on sustainable value capture (with plans for a curator model) aim to filter for high-quality projects, protecting investors while nurturing promising AI ventures within Bittensor.
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May 26, 2025

Has AI Revived the DePIN Sector? | Dmitriy Berenzon

0xResearch

AI
Key Takeaways:
  1. AI is DePIN's Demand Catalyst: The need for affordable AI compute is breathing new life and tangible demand into decentralized infrastructure.
  2. Value Accrual & Revenue are King: For DePIN tokens to thrive in liquid markets, clear mechanisms for value flow-through from opco revenue to the token are non-negotiable; "ARR is the new TVL."
  3. Distribution Trumps Decentralization (for now): Crypto-native solutions, especially in payments, must crack the distribution code or risk being outmaneuvered by Web2 incumbents leveraging their massive user bases.
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Crypto Podcasts

December 19, 2025

Are There Reasons To Be Optimistic? w/ Dim Selk

Steady Lads Podcast

Crypto
Key Takeaways:
  1. Market Structure Overhaul: The current token distribution model is broken. Expect continued pressure on altcoins until tokenomics evolve to prioritize product-market fit over continuous investor unlocks.
  2. Strategic Accumulation: This period of apathy is ideal for researching and accumulating Bitcoin and high-conviction RWAs. Cash is a strategic asset for deploying when opportunities arise.
  3. TradFi on Chain: The next growth vector for crypto involves capturing traditional finance flows through tokenized equities, commodities, and FX. Builders should focus on robust, order-book based solutions with improved user experience.
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December 19, 2025

Institutional Golden Bull Continues, System Update & Base App Recap, Stables in 2025 w/ Stablewatch

The Rollup

Crypto
Key Takeaways:
  1. Institutional Integration: Crypto is embedding itself into traditional finance, not replacing it. Expect more "everything apps" and verticalized services from major players.
  2. Yield Evolution: As interest rates decline, the demand for diversified, transparent yield-bearing stablecoins will intensify. Protocols with robust risk management and RWA exposure will lead.
  3. Creator Economy's Next Frontier: On-chain tools will redefine creator monetization, shifting from vanity metrics to direct value capture and deeper fan relationships.
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December 18, 2025

Why Privacy for Crypto Is in the Public Interest: DEX in the City

Unchained

Crypto
Key Takeaways:
  1. Strategic Implication: The shift in regulatory tone and corporate demand for privacy signals a maturation of the crypto industry. Solutions that balance privacy with accountability will capture significant market share.
  2. Builder/Investor Note: Focus on projects building privacy-preserving compliance tools and "programmable risk management" frameworks. These are the infrastructure plays for mainstream adoption. Avoid projects that offer absolute privacy without any recourse mechanisms, as they face significant regulatory risk.
  3. The "So What?": Over the next 6-12 months, expect increased innovation and investment in ZK-based privacy solutions that enable selective disclosure and verifiable compliance. This will be crucial for onboarding institutional capital and protecting individual users in a data-exposed world.
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December 18, 2025

Inside Robinhood's Big Super App Plan: ‘There's Still a Lot of Work to Be Done’

Unchained

Crypto
Key Takeaways:
  1. Integrated Finance is the Future: Robinhood's super app strategy, combining traditional and crypto assets, points to a future where financial services are consolidated and cross-pollinated.
  2. Builders: Simplify, Simplify, Simplify: The path to mainstream crypto adoption requires abstracting away technical details. Focus on product utility, not underlying blockchain mechanics.
  3. Tokenization's Long Game: Expect tokenization to redefine access to private markets and real-world assets, potentially disrupting traditional capital raising and ownership structures over the next 2-5 years.
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December 19, 2025

Crypto 'Is Dead' - DATs: A Buying Opportunity? Plus: Figure's IPO & Trump's WLFI in Trouble

Unchained

Crypto
Key Takeaways:
  1. Strategic Implication: The crypto industry is moving beyond speculative cycles, driven by the integration of real-world assets and the pursuit of tangible efficiencies by both startups and traditional financial giants.
  2. Builder/Investor Note: Builders should prioritize utility and cost reduction for mainstream users, while investors must scrutinize projects for sustainable business models and genuine decentralization, rather than relying on hype or incentive schemes.
  3. The "So What?": Regulatory clarity, particularly around DeFi and asset classification, will shape the next 6-12 months, determining which projects thrive by truly delivering value and which struggle under increased scrutiny.
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December 18, 2025

If Ethereum and Solana Had a Baby, It Would Be Monad

The DCo Podcast

Crypto
Key Takeaways:
  1. Strategic Implication: Monad represents a significant bet on vertical scaling of Layer 1s, aiming to unlock a new class of high-performance DeFi applications by directly addressing core execution bottlenecks.
  2. Builder/Investor Note: Full EVM bytecode compatibility means existing Ethereum dApps can migrate with minimal changes, immediately benefiting from 10,000+ TPS and 1-second finality. This opens doors for high-frequency DeFi, on-chain order books, and complex AI/ML applications.
  3. The "So What?": If Monad delivers on its promises, it could validate a powerful alternative scaling path for crypto, shifting focus back to base-layer innovation and enabling decentralized finance to truly compete with centralized exchanges in performance and cost within the next 6-12 months.
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