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AI Podcasts

November 16, 2025

Rawson Haverty presents "US & China AI: Lessons from Across the Pacific" | dAGI Summit 2025

Delphi Digital

AI
Key Takeaways:
  1. US Leads in Capital-Intensive Frontier AI; China Excels at Industrial Diffusion. The US leverages deep capital markets for its massive compute buildout and AGI research, while China uses state direction to embed AI into its vast industrial base via open-source models and hardware.
  2. Market Structure Dictates AI Strategy. The US "efficient oligopoly" model prioritizes global dominance and profit reinvestment by a few players. China's "subjugated swarm" model creates intense domestic competition, driving down prices and accelerating adoption at the cost of profitability.
  3. Geopolitical Tension May Be a Necessary Stabilizer. The competition between the US's freedom-oriented, frontier-pushing approach and China's stability-focused, diffusion-driven model creates a complementary tension that could be essential for navigating the "narrow corridor" between AI-driven totalitarianism and uncontrollable chaos.
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November 13, 2025

How Will AI Change Gaming Development? (A Dev’s Take)

The DCo Podcast

AI
Key Takeaways:
  1. Development timelines are collapsing from months to days. AI allows developers to swap entire asset libraries or generate new game concepts at unprecedented speed, turning a two-month art project into a day's work.
  2. The lifespan of any single game is shrinking. Prepare for a world of disposable entertainment. As AI floods the market with content, the strategy will pivot from creating one long-lasting hit to deploying a rapid succession of engaging experiences.
  3. Games are the next evolution of the attention economy. Just as memes became a core tool for community-building around tokens, easily created games will be the next engine for capturing and directing user attention in a hyper-competitive digital world.
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November 11, 2025

AI Nerves, Crypto Realism, Privacy Coins, & Lessons From Trading

1000x Podcast

AI
Key Takeaways:
  1. Adopt a Stock Picker's Mentality. The crypto market is no longer a monolith where a rising tide lifts all boats. Focus on assets with real products, user growth, and cash flow, as the gap between winners and losers will only widen.
  2. Shorting is a Tactical Assault, Not a Siege. Don't "invest" in a short. The only viable short strategies are tactical, targeting specific events like VC unlocks or news-driven spikes. Otherwise, even "total scams" can 5x against you.
  3. Cultivate a Goldfish's Memory. The most critical trading skill is learning how to change your mind. Cut losing trades, forget the loss (but remember the lesson), and redeploy capital without emotional baggage. Stubbornness is a portfolio killer.
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November 11, 2025

Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users

a16z

AI
Key Takeaways:
  1. Word-of-mouth isn't a feature; it's the engine. Before spending a dime on marketing, obsess over the first 30 seconds of the user experience until people can't help but share it.
  2. Being different is better than being better. Don't build incrementally better slideware. Redefine the core primitives of your category, as Gamma did by moving beyond the 16x9 slide.
  3. Hire painfully slowly to protect your DNA. Resisting the temptation to scale headcount with user growth is a superpower. The goal isn't to hit a hiring target; it's to hire the best people.
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November 7, 2025

Amjad Masad & Adam D’Angelo: How Far Are We From AGI?

a16z

AI
Key Takeaways:
  1. AGI Is a Definitional Debate. Progress toward an AI that can replace a remote worker is happening fast. However, achieving "true" human-like learning efficiency may require an entirely new paradigm beyond scaling current LLMs.
  2. The New Creator Economy Is Code. AI is turning software development into a mainstream creative pursuit, empowering a new class of solo entrepreneurs who can build what previously required entire teams.
  3. Incumbents Learned Their Lesson. Unlike past tech shifts, today's giants are aggressively adopting AI, making it both a sustaining *and* disruptive force. The market is large enough for both incumbents and startups to create massive value.
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November 6, 2025

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

a16z

AI
Key Takeaways:
  1. Build the Tools, Not Just the House: CZI’s greatest leverage comes from creating open-source tools and datasets. By building the fundamental infrastructure, they empower the entire scientific community—from academic labs to startups—to accelerate discovery.
  2. Data Is the New Microscope: The future of biology hinges on a tight feedback loop between generating novel, purpose-built datasets and training domain-specific AI models on them. This synergy is unlocking insights that were previously impossible.
  3. Virtual Biology Is the Next Frontier: Simulating biology computationally with "virtual cells" will become the new standard for research, enabling scientists to test riskier hypotheses faster and cheaper, dramatically compressing the timeline for major breakthroughs.
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November 5, 2025

Seeing The Future from AI Companions to Personal Software

a16z

AI
Key Takeaways:
  1. The Interface is the Bottleneck. Today's chatbots are the MS-DOS of AI. The next trillion dollars of value will be unlocked not by the models themselves, but by the new "Windows/Mac OS" interface that makes AI accessible and useful for everyone.
  2. Every Creator Will Build Software. The distinction between a content creator and a software developer is collapsing. The next platforms will empower anyone to build mini-apps, turning software into a new medium for community, expression, and monetization.
  3. Ditch the Voice-Only Dream. The Her-inspired fantasy of a screenless, voice-only AI future is a dead end. The winning AI device will be screen-first, built around an AI-native OS that makes software deeply personal and context-aware.
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November 4, 2025

Rollup TV: Aria Protocol, Money Moves Fast EP 8, Crossmint

The Rollup

AI
Key Takeaways:
  1. Culture is the Newest Yield-Bearing Asset: Arya Protocol proves that intellectual property, from music royalties to digital art, can be tokenized into stable, income-generating investments, moving beyond crypto’s speculative roots.
  2. Fintech's Crypto FOMO is Reshaping Finance: The race is on. Traditional payment giants are rapidly adopting stablecoins, not as a gimmick, but as a critical infrastructure upgrade for building faster, cheaper, and more inclusive global financial products.
  3. Money is Becoming Natively Programmable for AI: The future of commerce and finance will be run by AI agents. Stablecoins provide the missing piece—a programmable, automated payment layer that bypasses the friction of traditional banking, unleashing a new wave of economic activity.
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November 4, 2025

ElevenLabs CEO: Why Voice is the Next AI Interface

a16z

AI
Key Takeaways:
  1. **Structure Dictates Speed:** A flat hierarchy with small, autonomous teams is the key to maintaining startup velocity at scale. Extreme ownership is the goal; traditional corporate structures are the enemy.
  2. **Align Incentives, Explicitly:** As a company matures, passion gives way to process. In sales, commissions become a lagging indicator of strategy. Ensure incentive structures explicitly reward strategic decisions, not just closing any deal.
  3. **Balance Ambition with Delivery:** Don't let the quest for a perfect, research-led solution kill your product momentum. Implement clear rules to decide when to ship a practical fix now and when to wait for the scientific breakthrough.
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Crypto Podcasts

December 21, 2025

2025 Year in Review: Why RWAs are Taking Off in 2026 with Chris Yin and Teddy Pornprinya of Plume

The Rollup

Crypto
Key Takeaways:
  1. Strategic Implication: The RWA market is poised for a "nuclear" expansion in 2026, driven by declining T-bill yields and a global search for higher returns. Expect 25-50x growth, pushing total value to $400B-$800B.
  2. Builder/Investor Note: Focus investments on RWA infrastructure and tooling (lending, borrowing, insurance, core chains) rather than just holding RWA assets. These platforms capture fees from growing volume. Builders should prioritize crypto-native composability and permissionless access.
  3. The "So What?": The convergence of traditional finance's yield needs with crypto's permissionless innovation, particularly in emerging markets, will redefine capital allocation and create new financial primitives over the next 6-12 months.
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December 21, 2025

How Lighter ate away Hyperliquid’s moat

The Gwart Show

Crypto
Key Takeaways:
  1. Verifiable Infrastructure: Lighter's ZK-centric approach to verifiability positions it as a robust platform for institutional adoption as regulatory clarity improves.
  2. Market Expansion Strategy: The zero-fee model is a bold play to expand the DeFi trading market, potentially attracting a new wave of users and professional liquidity.
  3. Ecosystem Play: The "sidecar protocol" and planned expansion into RWAs, options, and fixed income signal Lighter's ambition to become a foundational layer for a broader, more integrated DeFi.
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December 20, 2025

Will Trump’s ‘DeFi’ Platform Break Market Structure Law?

Unchained

Crypto
Key Takeaways:
  1. Strategic Implication: The WLF case highlights a critical tension between marketing claims and regulatory reality in the crypto space. Clear market structure laws will force projects to align their operations with their stated decentralization.
  2. Builder/Investor Note: Projects claiming "DeFi" status but exhibiting centralized control (e.g., insider veto power, token freezing, high insider token concentration) face significant regulatory risk. Builders should audit their governance and token distribution against emerging "bright line" tests.
  3. The "So What?": The outcome of WLF's regulatory classification, and the broader market structure bill, will define the operating environment for crypto for the next 6-12 months, determining which projects thrive under new legal frameworks.
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December 19, 2025

Is 2025 Crypto's Dot-com Moment? | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Strategic Implication: The crypto market is undergoing a structural re-rating. Focus on companies building essential infrastructure and solving real-world problems, not just speculative tokens.
  2. Builder/Investor Note: Private crypto equity is attracting significant capital. Builders should focus on full-stack fintech solutions and direct customer engagement. Investors should identify structurally advantaged companies with clear business models.
  3. The "So What?": The next 6-12 months will see continued decoupling. A potential softening of AI hype could redirect capital, but the long-term winners in crypto will be those providing tangible utility and robust infrastructure.
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December 19, 2025

Stablecoins in 2025: The Breakout Year In Review (And What Comes Next...)

The Rollup

Crypto
Key Takeaways:
  1. Strategic Implication: The YBS market is shifting from speculative yield farming to a foundational layer for tokenized finance, driven by institutional interest and RWA integration.
  2. Builder/Investor Note: Prioritize YBS protocols with diversified yield strategies and robust risk management (e.g., first-loss tranches). Builders should focus on RWA infrastructure and sustainable, real-world yield mechanisms.
  3. The "So What?": The convergence of declining traditional rates and maturing RWA tokenization will funnel significant capital into diversified, transparent YBS. Protocols prioritizing these elements will capture the lion's share of the projected $100 billion TVL.
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December 20, 2025

2025 Year In Review Special: AI & Tokenization

The Rollup

Crypto
Key Takeaways:
  1. RWA as a Macro Trend: The tokenization of real-world assets is not a niche but a fundamental shift, attracting significant institutional capital and driving a search for yield beyond traditional instruments.
  2. AI Integration is the Moat: For builders, success in AI hinges on deep integration into existing platforms and workflows, coupled with robust trust and safety mechanisms for autonomous agents.
  3. The Hybrid Future: The market is moving towards centralized frontends (banks, exchanges) offering decentralized, on-chain products. This model bridges user familiarity with crypto-native efficiency, unlocking massive adoption in the next 6-12 months.
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