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AI Podcasts

December 31, 2025

Infinity, Paradoxes, Gödel Incompleteness & the Mathematical Multiverse | Lex Fridman Podcast #488

Lex Fridman

AI
Key Takeaways:
  1. The move from a singular "Universe" view to a "Multiverse" perspective mirrors the transition from centralized monoliths to fragmented, interoperable ecosystems.
  2. Build systems that fail gracefully when hitting Gödelian limits.
  3. Truth is a vast ocean while proof is a small boat. Your roadmap must account for the reality that your system will eventually encounter truths it cannot verify.
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December 31, 2025

AI in 2026: 3 Predictions For What’s To Come (a16z Big Ideas)

a16z

AI
Key Takeaways:
  1. The Macro Pivot: Outcome-Based Intelligence. We are moving from AI as a Service to Results as a Service where software value is tied to revenue generation rather than seat licenses.
  2. The Tactical Edge: Verticalize the Data. Build in sectors with non-public outcome data to create a compounding moat that resists commoditization by foundation models.
  3. The winners of 2026 will be those who use AI to solve core human needs for connection and discovery while building defensible, data-rich business models.
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December 31, 2025

AutoGrad Changed Everything (Not Transformers) [Dr. Jeff Beck]

Machine Learning Street Talk

AI
Key Takeaways:
  1. The Macro Transition: Moving from "Big Model" monoliths to "Lots of Little Models" where distributed Bayesian assets represent specific physical objects.
  2. The Tactical Edge: Prioritize "Object-Centered" architectures that track uncertainty. This allows robots to "phone a friend" when encountering novel data.
  3. The LLM era is hitting a wall of implicit representation. The next 12 months belong to those building explicit, causal world models grounded in physics rather than language.
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December 31, 2025

[State of Post-Training] From GPT-4.1 to 5.1: RLVR, Agent & Token Efficiency — Josh McGrath, OpenAI

Latent Space

AI
Key Takeaways:
  1. The move from "bigger is better" to "smarter is cheaper" as token efficiency becomes the primary metric for agentic success.
  2. Prioritize building on models that demonstrate high performance on "graph walk" evals to ensure your long-context applications actually work.
  3. Utilitarian and efficient models that prioritize task completion over cheery personality will dominate the developer market.
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December 31, 2025

[State of Evals] LMArena's $100M Vision — Anastasios Angelopoulos, LMArena

Latent Space

AI
Key Takeaways:
  1. The Macro Trend: The transition from static benchmarks to live human-in-the-loop evaluation. As models saturate fixed tests, the only remaining signal is subjective human preference at scale.
  2. The Tactical Edge: Monitor secret model drops on Arena to spot frontier capabilities before official releases. This provides a lead time advantage for builders choosing their tech stack.
  3. The Bottom Line: Arena is the new kingmaker. If you are building AI products, their expert-tier data is the most reliable map for navigating the frontier.
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December 31, 2025

[State of Context Engineering] Agentic RAG, Context Rot, MCP, Subagents — Nina Lopatina, Contextual

Latent Space

AI
Key Takeaways:
  1. The move from small models to medium models (15B to 70B) suggests that reasoning capability is outstripping the desire for low-latency edge deployment.
  2. Implement instruction-following re-rankers to prune your context window. This prevents the model from getting confused by irrelevant data.
  3. Stop building toys. The next year belongs to those who can build full agentic systems that handle billions of tokens without losing the plot.
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December 31, 2025

[NeurIPS Best Paper] 1000 Layer Networks for Self-Supervised RL — Kevin Wang et al, Princeton

Latent Space

AI
Key Takeaways:
  1. The wall between RL and self-supervised learning is crumbling, leading to a unified "representation-first" approach to AI.
  2. Swap your reward-heavy objectives for contrastive representation learning to access deeper, more stable architectures.
  3. If you aren't planning for RL models with 100x the current depth, you're building for the past.
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December 31, 2025

[State of AI Papers 2025] Fixing Research with Social Signals, OCR & Implementation — Team AlphaXiv

Latent Space

AI
Key Takeaways:
  1. Academic research is transitioning from a "publish or perish" PDF culture to an "implement or ignore" code culture.
  2. Use AlphaXiv to filter research by social signal and implementation ease rather than just keyword relevance.
  3. The PDF is an antiquated artifact. In 2025, the value of a paper is measured by the speed at which a developer can spin up its Docker container.
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December 31, 2025

[State of MechInterp] SAEs in Production, Circuit Tracing, AI4Science, "Pragmatic" Interp — Goodfire

Latent Space

AI
Key Takeaways:
  1. The Macro Trend: The transition from black box scaling to transparent steering. As models enter regulated industries, the ability to prove why a model made a decision becomes more valuable than the decision itself.
  2. The Tactical Edge: Deploy sidecar models for monitoring. Instead of using expensive LLM-as-a-judge prompts, probe specific internal features to catch hallucinations at the activation level.
  3. The Bottom Line: The next year belongs to the pragmatic researchers. If you cannot explain your model's reasoning, you will not be allowed to deploy it in high-stakes environments.
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Crypto Podcasts

December 21, 2025

How Lighter ate away Hyperliquid’s moat

The Gwart Show

Crypto
Key Takeaways:
  1. Verifiable Infrastructure: Lighter's ZK-centric approach to verifiability positions it as a robust platform for institutional adoption as regulatory clarity improves.
  2. Market Expansion Strategy: The zero-fee model is a bold play to expand the DeFi trading market, potentially attracting a new wave of users and professional liquidity.
  3. Ecosystem Play: The "sidecar protocol" and planned expansion into RWAs, options, and fixed income signal Lighter's ambition to become a foundational layer for a broader, more integrated DeFi.
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December 20, 2025

Will Trump’s ‘DeFi’ Platform Break Market Structure Law?

Unchained

Crypto
Key Takeaways:
  1. Strategic Implication: The WLF case highlights a critical tension between marketing claims and regulatory reality in the crypto space. Clear market structure laws will force projects to align their operations with their stated decentralization.
  2. Builder/Investor Note: Projects claiming "DeFi" status but exhibiting centralized control (e.g., insider veto power, token freezing, high insider token concentration) face significant regulatory risk. Builders should audit their governance and token distribution against emerging "bright line" tests.
  3. The "So What?": The outcome of WLF's regulatory classification, and the broader market structure bill, will define the operating environment for crypto for the next 6-12 months, determining which projects thrive under new legal frameworks.
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December 19, 2025

Is 2025 Crypto's Dot-com Moment? | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Strategic Implication: The crypto market is undergoing a structural re-rating. Focus on companies building essential infrastructure and solving real-world problems, not just speculative tokens.
  2. Builder/Investor Note: Private crypto equity is attracting significant capital. Builders should focus on full-stack fintech solutions and direct customer engagement. Investors should identify structurally advantaged companies with clear business models.
  3. The "So What?": The next 6-12 months will see continued decoupling. A potential softening of AI hype could redirect capital, but the long-term winners in crypto will be those providing tangible utility and robust infrastructure.
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December 19, 2025

Stablecoins in 2025: The Breakout Year In Review (And What Comes Next...)

The Rollup

Crypto
Key Takeaways:
  1. Strategic Implication: The YBS market is shifting from speculative yield farming to a foundational layer for tokenized finance, driven by institutional interest and RWA integration.
  2. Builder/Investor Note: Prioritize YBS protocols with diversified yield strategies and robust risk management (e.g., first-loss tranches). Builders should focus on RWA infrastructure and sustainable, real-world yield mechanisms.
  3. The "So What?": The convergence of declining traditional rates and maturing RWA tokenization will funnel significant capital into diversified, transparent YBS. Protocols prioritizing these elements will capture the lion's share of the projected $100 billion TVL.
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December 20, 2025

2025 Year In Review Special: AI & Tokenization

The Rollup

Crypto
Key Takeaways:
  1. RWA as a Macro Trend: The tokenization of real-world assets is not a niche but a fundamental shift, attracting significant institutional capital and driving a search for yield beyond traditional instruments.
  2. AI Integration is the Moat: For builders, success in AI hinges on deep integration into existing platforms and workflows, coupled with robust trust and safety mechanisms for autonomous agents.
  3. The Hybrid Future: The market is moving towards centralized frontends (banks, exchanges) offering decentralized, on-chain products. This model bridges user familiarity with crypto-native efficiency, unlocking massive adoption in the next 6-12 months.
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December 20, 2025

How AI Agents Are Replacing Hedge Fund Managers with Pei Chen of Theoriq

The Rollup

Crypto
Key Takeaways:
  1. Agentic Finance is Here: Autonomous AI agents will manage significant capital, requiring robust guardrails and verifiable security.
  2. Distribution Wins: For AI models, deep integration into existing user ecosystems and multi-platform functionality will drive adoption and performance.
  3. Human Roles Evolve: Builders must design for human-AI collaboration, focusing on AI as an accelerator for specialized human expertise, not a full replacement.
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