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AI Podcasts

January 15, 2026

Ben & Marc: Why Everything Is About to Get 10x Bigger

a16z

AI
Key Takeaways:
  1. The transition from software eating the world to AI reinventing the computer means every existing market cap is a floor.
  2. Prioritize the non-fungible creator by providing monetization tools that bypass legacy gatekeepers.
  3. We are entering a period of asymmetric payoffs where the art of picking original thinkers matters more than historical data.
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January 13, 2026

Paul Rosolie: Uncontacted Tribes in the Amazon Jungle | Lex Fridman Podcast #489

Lex Fridman

AI
Key Takeaways:
  1. The Macro Trend: Biological Sovereignty. As global systems destabilize, the Amazon remains the most critical piece of biological infrastructure on the planet.
  2. The Tactical Edge: Support Jungle Keepers. Direct capital to organizations that convert loggers into rangers to secure land concessions.
  3. The Amazon is a finite asset under active siege. Protecting it requires a blend of primitive survival skills and high-tech surveillance over the next 18 months.
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January 12, 2026

Jensen Huang says robots will have human capabilities this year! The Robots at CES Had.. Other Plans

Turing Post

AI
Key Takeaways:
  1. The Macro Pivot: As generative AI masters simulation, the physical world becomes a high-fidelity playground for software.
  2. The Tactical Edge: Invest in the "brain" layer rather than the "limb" layer. Software that can generalize across different hardware forms will capture the most value.
  3. The next decade belongs to embodied AI that reasons in real time. If you are waiting for the hardware to look perfect before paying attention, you will miss the moment the software takes over the physical world.
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January 12, 2026

Your MCP Server is Bad (and you should feel bad) - Jeremiah Lowin, Prefect

AI Engineer

AI
Key Takeaways:
  1. The Macro Pivot: Context as Product. We are moving from raw data transport to opinionated context delivery.
  2. The Tactical Edge: Prune your endpoints. Remove any tool that requires more than one step to achieve a business result.
  3. The Bottom Line: The winners of the agentic era will be those who build the best Agentic Interface Guidelines.
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January 12, 2026

OpenAI + @Temporalio : Building Durable, Production Ready Agents - Cornelia Davis, Temporal

AI Engineer

AI
Key Takeaways:
  1. The industry is moving from "Agent as a Script" to "Agent as a Durable Service" where state management is handled by the infrastructure.
  2. Wrap your existing API tools in the `activity_as_tool` function to gain automatic retries and execution history.
  3. Reliability is the only moat in the agentic economy. If your agent cannot survive a server restart during a three-day task, it is not ready for the enterprise.
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January 13, 2026

How Ladder Became #1 Strength Training App

Invest Like The Best

AI
Key Takeaways:
  1. The Macro Trend: The move from fragmented content libraries to integrated health systems where AI synthesizes biomarkers and movement.
  2. The Tactical Edge: Construct internal LLM tools to categorize qualitative feedback. This turns thousands of raw reviews into a precise roadmap.
  3. The Bottom Line: Building a $100M ARR consumer app requires mastery of both growth loops and product retention. Solve for the daily habit to win the long game.
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January 13, 2026

Ben Horowitz on Investing in AI: AI Bubbles, Economic Impact, and VC Acceleration

a16z

AI
Key Takeaways:
  1. The transition from general-purpose AI to specialized application layers. As foundation models commoditize, value migrates to the "fat tail" of human-centric complexity.
  2. Prioritize building or investing in "DNA of the future" companies that incumbents must eventually acquire to survive. Focus on winning the "point of attack" by staying deep in the technical details.
  3. We are in a unique market where demand growth justifies high valuations. Success over the next year depends on identifying founders who are the absolute best in the world at one specific thing.
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January 13, 2026

It's Time To Build

a16z

AI
Key Takeaways:
  1. The Macro Shift: Infrastructure Invisibility. As core technologies become background noise, value moves from the pipes to the unique experiences built on top of them.
  2. The Tactical Edge: Reject Mediocrity. Audit your product for average features and replace them with high-conviction improvements that competitors are too lazy to attempt.
  3. The Bottom Line: Building is the only way to ensure the future happens. If you do not create the next version of reality, you are stuck living in an outdated vision.
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January 13, 2026

Nothing’s Carl Pei on Building a $1B Smartphone Company and Why He Thinks About Death Every Week

The Generalist

AI
Key Takeaways:
  1. The transition from hardware specs to emotional hardware where brand identity and OS-native AI become the primary moats.
  2. Prioritize arbitrage opportunities in marketing by finding underpriced attention on platforms like TikTok before they become crowded.
  3. Success in mature markets requires a Genghis Khan method: be a talent scout, stay open-minded to global supply chains, and use design to win the emotional battle for the consumer's pocket.
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Crypto Podcasts

December 21, 2025

2025 Year in Review: Why RWAs are Taking Off in 2026 with Chris Yin and Teddy Pornprinya of Plume

The Rollup

Crypto
Key Takeaways:
  1. Strategic Implication: The RWA market is poised for a "nuclear" expansion in 2026, driven by declining T-bill yields and a global search for higher returns. Expect 25-50x growth, pushing total value to $400B-$800B.
  2. Builder/Investor Note: Focus investments on RWA infrastructure and tooling (lending, borrowing, insurance, core chains) rather than just holding RWA assets. These platforms capture fees from growing volume. Builders should prioritize crypto-native composability and permissionless access.
  3. The "So What?": The convergence of traditional finance's yield needs with crypto's permissionless innovation, particularly in emerging markets, will redefine capital allocation and create new financial primitives over the next 6-12 months.
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December 21, 2025

How Lighter ate away Hyperliquid’s moat

The Gwart Show

Crypto
Key Takeaways:
  1. Verifiable Infrastructure: Lighter's ZK-centric approach to verifiability positions it as a robust platform for institutional adoption as regulatory clarity improves.
  2. Market Expansion Strategy: The zero-fee model is a bold play to expand the DeFi trading market, potentially attracting a new wave of users and professional liquidity.
  3. Ecosystem Play: The "sidecar protocol" and planned expansion into RWAs, options, and fixed income signal Lighter's ambition to become a foundational layer for a broader, more integrated DeFi.
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December 20, 2025

Will Trump’s ‘DeFi’ Platform Break Market Structure Law?

Unchained

Crypto
Key Takeaways:
  1. Strategic Implication: The WLF case highlights a critical tension between marketing claims and regulatory reality in the crypto space. Clear market structure laws will force projects to align their operations with their stated decentralization.
  2. Builder/Investor Note: Projects claiming "DeFi" status but exhibiting centralized control (e.g., insider veto power, token freezing, high insider token concentration) face significant regulatory risk. Builders should audit their governance and token distribution against emerging "bright line" tests.
  3. The "So What?": The outcome of WLF's regulatory classification, and the broader market structure bill, will define the operating environment for crypto for the next 6-12 months, determining which projects thrive under new legal frameworks.
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December 19, 2025

Is 2025 Crypto's Dot-com Moment? | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Strategic Implication: The crypto market is undergoing a structural re-rating. Focus on companies building essential infrastructure and solving real-world problems, not just speculative tokens.
  2. Builder/Investor Note: Private crypto equity is attracting significant capital. Builders should focus on full-stack fintech solutions and direct customer engagement. Investors should identify structurally advantaged companies with clear business models.
  3. The "So What?": The next 6-12 months will see continued decoupling. A potential softening of AI hype could redirect capital, but the long-term winners in crypto will be those providing tangible utility and robust infrastructure.
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December 19, 2025

Stablecoins in 2025: The Breakout Year In Review (And What Comes Next...)

The Rollup

Crypto
Key Takeaways:
  1. Strategic Implication: The YBS market is shifting from speculative yield farming to a foundational layer for tokenized finance, driven by institutional interest and RWA integration.
  2. Builder/Investor Note: Prioritize YBS protocols with diversified yield strategies and robust risk management (e.g., first-loss tranches). Builders should focus on RWA infrastructure and sustainable, real-world yield mechanisms.
  3. The "So What?": The convergence of declining traditional rates and maturing RWA tokenization will funnel significant capital into diversified, transparent YBS. Protocols prioritizing these elements will capture the lion's share of the projected $100 billion TVL.
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December 20, 2025

2025 Year In Review Special: AI & Tokenization

The Rollup

Crypto
Key Takeaways:
  1. RWA as a Macro Trend: The tokenization of real-world assets is not a niche but a fundamental shift, attracting significant institutional capital and driving a search for yield beyond traditional instruments.
  2. AI Integration is the Moat: For builders, success in AI hinges on deep integration into existing platforms and workflows, coupled with robust trust and safety mechanisms for autonomous agents.
  3. The Hybrid Future: The market is moving towards centralized frontends (banks, exchanges) offering decentralized, on-chain products. This model bridges user familiarity with crypto-native efficiency, unlocking massive adoption in the next 6-12 months.
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