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AI Podcasts

February 3, 2026

Inside The Biggest Uranium Deal In 50 Years | Scott Nolan, CEO of General Matter

The Generalist

AI
Key Takeaways:
  1. Geopolitical tensions and the insatiable energy demands of the AI revolution are forcing a re-evaluation of national energy security.
  2. Invest in companies applying "first principles" engineering and a commercial cost-reduction mindset to foundational, capital-intensive industries.
  3. The US nuclear fuel supply chain is undergoing a rapid, government-backed revitalization.
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February 3, 2026

OpenClaw Makes AI Agents and CPUs Get Real

Semi Doped

AI
Key Takeaways:
  1. The macro trend of autonomous AI agents is shifting compute demand beyond GPUs, creating an unexpected CPU crunch and forcing a re-evaluation of on-premise inference and cost-optimized model routing for security and efficiency.
  2. Investigate hybrid compute strategies, combining secure local environments (Mac Minis, home servers) with cloud-based LLMs, and explore multi-model API gateways like OpenRouter to optimize agent costs and performance.
  3. AI agents are here, demanding a rethink of your compute stack and security protocols. Prepare for a future where CPU capacity, not just GPU, becomes a critical bottleneck, and strategic cost management for diverse AI models is non-negotiable for competitive advantage.
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February 4, 2026

⚡️ Context graphs: AI’s trillion-dollar opportunity — Jaya Gupta, Ashu Garg, Foundation Capital

Latent Space

AI
Key Takeaways:
  1. The move from general-purpose LLMs to specialized AI agents demands a new data architecture that captures the *why* of decisions, not just the *what*. This creates a new, defensible layer of institutional memory, moving value from raw model IP to proprietary decision intelligence.
  2. Invest in or build agentic systems that are in the *orchestration path* of specific business processes. This allows for the organic capture of decision traces, forming a proprietary context graph that incumbents cannot easily replicate.
  3. Over the next 12 months, the ability to build and extract value from context graphs will define the winners in the enterprise AI space, creating a new "context graph stack" that will be 10x more valuable than the modern data stack.
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February 2, 2026

We Entered an Era Where No One Knows What Comes Next

Turing Post

AI
Key Takeaways:
  1. AI's progress has transitioned from a linear, bottleneck-driven model to a multi-layered, interconnected explosion of advancements. This makes traditional long-term forecasting obsolete.
  2. Prioritize building and investing in adaptable systems and teams that can rapidly respond to emergent opportunities across diverse AI layers. Focus on robust interfaces and composability rather than betting on a single "next frontier."
  3. The next 6-12 months will test our ability to operate in an environment where the future is increasingly opaque. Success will come from embracing this unpredictability, focusing on present opportunities, and building for resilience against an unknowable future.
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February 2, 2026

Ben Horowitz & David Solomon on Why Scale Is The Only Thing That Matters

a16z

AI
Key Takeaways:
  1. The Macro Shift: Unprecedented fiscal and monetary stimulus, combined with an AI-driven capital investment super cycle, creates a "sweet spot" for financial assets and growth technology. This favors institutions with scale and adaptability.
  2. The Tactical Edge: Prioritize investments in companies with proprietary data and significant GPU access, as these are new competitive moats in the AI era. For founders, secure capital to compete against well-funded incumbents.
  3. The Bottom Line: Scale and strategic capital deployment are paramount. Whether a financial giant or tech insurgent, the ability to grow, adapt to AI's new rules, and handle regulatory currents will determine relevance and success.
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February 1, 2026

Google’s AI Stack Is Unmatched (No One Else Is Even Close) w/ Ejaaz

Milk Road AI

AI
Key Takeaways:
  1. The AI industry is consolidating around players with deep, proprietary data and infrastructure, transforming general LLMs into personalized, transactional agents. This means value accrues to those who can not only build powerful models but also distribute them at scale and integrate them into daily life.
  2. Investigate companies building on top of Google's AI ecosystem or those creating niche applications that use personalized AI. Focus on solutions that move beyond simple chatbots to actual task execution and intent capture.
  3. Google's strategic moves, particularly with Apple and in e-commerce, signal a future where AI is deeply embedded in every digital interaction. Understanding this shift is crucial for identifying where value will be created and captured.
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January 31, 2026

State of AI in 2026: LLMs, Coding, Scaling Laws, China, Agents, GPUs, AGI | Lex Fridman Podcast #490

Lex Fridman

AI
Key Takeaways:
  1. The AI industry is pivoting from a singular AGI pursuit to a multi-pronged approach, where specialized models, advanced post-training, and geopolitical open-source competition redefine competitive advantage and talent acquisition.
  2. Invest in infrastructure and expertise for advanced post-training techniques like RLVR and inference-time scaling, as these are the primary drivers of capability gains and cost efficiency in current LLM deployments.
  3. The next 6-12 months will see continued rapid iteration in AI, driven by compute scale and algorithmic refinement rather than architectural overhauls. Builders and investors should focus on specialized applications, human-in-the-loop systems, and the strategic implications of open-weight models to capture value in this evolving landscape.
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January 31, 2026

Inside a Chinese AI Lab: How MiniMax Builds Open Models

Turing Post

AI
Key Takeaways:
  1. The open-source AI movement is democratizing access to powerful models, but this decentralization shifts the burden of safety and robust environmental adaptation from central labs to individual builders.
  2. Prioritize investing in or building tools that provide robust, scalable evaluation and alignment frameworks for open-weight models.
  3. The next 6-12 months will see a race to solve environmental adaptability and human alignment in open-weight agentic AI. Success here will define the practical utility and safety of the next generation of AI applications.
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February 1, 2026

Google’s AI Stack Is Unmatched (No One Else Is Even Close) w/ Ejaaz

Milk Road AI

AI
Key Takeaways:
  1. Data is the New Moat, and Google Owns the Farm
  2. Apple's Billion-Dollar Bet on Gemini
  3. Google's Intent to Own E-commerce and Personal AI
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Crypto Podcasts

December 21, 2025

How Lighter ate away Hyperliquid’s moat

The Gwart Show

Crypto
Key Takeaways:
  1. Verifiable Infrastructure: Lighter's ZK-centric approach to verifiability positions it as a robust platform for institutional adoption as regulatory clarity improves.
  2. Market Expansion Strategy: The zero-fee model is a bold play to expand the DeFi trading market, potentially attracting a new wave of users and professional liquidity.
  3. Ecosystem Play: The "sidecar protocol" and planned expansion into RWAs, options, and fixed income signal Lighter's ambition to become a foundational layer for a broader, more integrated DeFi.
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December 20, 2025

Will Trump’s ‘DeFi’ Platform Break Market Structure Law?

Unchained

Crypto
Key Takeaways:
  1. Strategic Implication: The WLF case highlights a critical tension between marketing claims and regulatory reality in the crypto space. Clear market structure laws will force projects to align their operations with their stated decentralization.
  2. Builder/Investor Note: Projects claiming "DeFi" status but exhibiting centralized control (e.g., insider veto power, token freezing, high insider token concentration) face significant regulatory risk. Builders should audit their governance and token distribution against emerging "bright line" tests.
  3. The "So What?": The outcome of WLF's regulatory classification, and the broader market structure bill, will define the operating environment for crypto for the next 6-12 months, determining which projects thrive under new legal frameworks.
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December 19, 2025

Is 2025 Crypto's Dot-com Moment? | Weekly Roundup

Empire

Crypto
Key Takeaways:
  1. Strategic Implication: The crypto market is undergoing a structural re-rating. Focus on companies building essential infrastructure and solving real-world problems, not just speculative tokens.
  2. Builder/Investor Note: Private crypto equity is attracting significant capital. Builders should focus on full-stack fintech solutions and direct customer engagement. Investors should identify structurally advantaged companies with clear business models.
  3. The "So What?": The next 6-12 months will see continued decoupling. A potential softening of AI hype could redirect capital, but the long-term winners in crypto will be those providing tangible utility and robust infrastructure.
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December 19, 2025

Stablecoins in 2025: The Breakout Year In Review (And What Comes Next...)

The Rollup

Crypto
Key Takeaways:
  1. Strategic Implication: The YBS market is shifting from speculative yield farming to a foundational layer for tokenized finance, driven by institutional interest and RWA integration.
  2. Builder/Investor Note: Prioritize YBS protocols with diversified yield strategies and robust risk management (e.g., first-loss tranches). Builders should focus on RWA infrastructure and sustainable, real-world yield mechanisms.
  3. The "So What?": The convergence of declining traditional rates and maturing RWA tokenization will funnel significant capital into diversified, transparent YBS. Protocols prioritizing these elements will capture the lion's share of the projected $100 billion TVL.
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December 20, 2025

2025 Year In Review Special: AI & Tokenization

The Rollup

Crypto
Key Takeaways:
  1. RWA as a Macro Trend: The tokenization of real-world assets is not a niche but a fundamental shift, attracting significant institutional capital and driving a search for yield beyond traditional instruments.
  2. AI Integration is the Moat: For builders, success in AI hinges on deep integration into existing platforms and workflows, coupled with robust trust and safety mechanisms for autonomous agents.
  3. The Hybrid Future: The market is moving towards centralized frontends (banks, exchanges) offering decentralized, on-chain products. This model bridges user familiarity with crypto-native efficiency, unlocking massive adoption in the next 6-12 months.
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December 20, 2025

How AI Agents Are Replacing Hedge Fund Managers with Pei Chen of Theoriq

The Rollup

Crypto
Key Takeaways:
  1. Agentic Finance is Here: Autonomous AI agents will manage significant capital, requiring robust guardrails and verifiable security.
  2. Distribution Wins: For AI models, deep integration into existing user ecosystems and multi-platform functionality will drive adoption and performance.
  3. Human Roles Evolve: Builders must design for human-AI collaboration, focusing on AI as an accelerator for specialized human expertise, not a full replacement.
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