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AI Podcasts

December 20, 2025

Are AI Benchmarks Telling The Full Story? [SPONSORED]

Machine Learning Street Talk

AI
Key Takeaways:
  1. Strategic Shift: The market will increasingly demand AI models evaluated on human-centric metrics, not just technical benchmarks. Companies prioritizing user experience and safety will gain a competitive edge.
  2. Builder/Investor Note: Investigate companies developing or utilizing advanced, demographically representative human evaluation frameworks. These are crucial for building defensible, user-aligned AI products.
  3. The "So What?": Over the next 6-12 months, expect a growing focus on AI safety, ethical alignment, and nuanced human preference data. The "Wild West" of AI evaluation is ending, paving the way for more robust, trustworthy systems.
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December 17, 2025

Rethinking Pre-Training for Agentic AI [Aakanksha Chowdhery] - 759

The TWIML AI Podcast with Sam Charrington

AI
Key Takeaways:
  1. Strategic Implication: The next frontier in AI is agentic, and progress hinges on fundamental pre-training innovation, not just post-training optimizations.
  2. Builder/Investor Note: Focus on teams with deep experience in scaling and debugging large models, as this is a high-capital, high-risk endeavor. Builders should prioritize developing new benchmarks for agentic capabilities.
  3. The "So What?": The industry needs to move beyond next-token prediction and static benchmarks to unlock truly capable, self-correcting AI agents in the next 6-12 months.
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December 17, 2025

Code World Model: Building World Models for Computation – Jacob Kahn, FAIR Meta

AI Engineer

AI
Key Takeaways:
  1. Shift in AI Development: The focus moves from syntax-aware code generation to execution-aware reasoning, enabling more robust and intelligent code agents.
  2. Builder/Investor Note: Prioritize tools and platforms that support explicit execution modeling and highly asynchronous, high-throughput RL training for agentic systems.
  3. The "So What?": AI that can simulate complex systems internally will drastically reduce development and testing costs, accelerating innovation in software and distributed systems over the next 6-12 months.
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December 17, 2025

AI Kernel Generation: What's working, what's not, what's next – Natalie Serrino, Gimlet Labs

AI Engineer

AI
Key Takeaways:
  1. Strategic Shift: AI-driven kernel generation is not replacing human genius but augmenting it, allowing experts to focus on novel breakthroughs while AI automates the application of known optimizations across a complex hardware landscape.
  2. Builder/Investor Note: Focus on robust validation and hardware-in-the-loop systems. Claims of "AI inventing new algorithms" in this domain are premature. The real value is in automating the "bag of tricks" for heterogeneous compute.
  3. The "So What?": This technology is critical for scaling agentic AI workloads. Expect significant investment in tools that abstract hardware complexity and enable efficient, automated optimization, driving down the cost of AI inference in the next 6-12 months.
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December 18, 2025

AI Consulting in Practice – NLW, Super ai

AI Engineer

AI
Key Takeaways:
  1. The Agent Economy is Here: Enterprises are moving past pilots with AI agents. Builders should focus on orchestration layers and human-agent interaction design.
  2. ROI Measurement is the Next Frontier: Investors should look for solutions that help organizations accurately track and attribute AI value beyond traditional metrics.
  3. Strategic AI, Not Spot Solutions: The biggest wins come from systematic, cross-organizational AI strategies that target new capabilities and revenue growth, not just incremental time savings.
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December 18, 2025

How to build an AI native company (even if your company is 50 years old) – Dan Shipper, Every

AI Engineer

AI
Key Takeaways:
  1. The 100% AI adoption threshold is a step-function change, not incremental. Companies that commit fully will outpace those with partial integration.
  2. Builders should prioritize "compounding engineering" by codifying knowledge into reusable prompts. This builds an organizational memory that accelerates future development exponentially.
  3. Re-evaluate team structures and roles. Single engineers can own complex products, and even technical managers can contribute code, shifting how organizations operate.
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December 17, 2025

“How We Can Eliminate Crime” | Ben Horowitz and Garrett Langley

a16z

AI
Key Takeaways:
  1. Effective crime reduction requires a shift from reactive punishment to proactive, intelligence-driven deterrence, making it highly probable for criminals to be caught.
  2. The market for AI-powered public safety technology, particularly solutions that integrate data for precision and accountability, presents a significant opportunity. Public-private partnerships are a key funding mechanism.
  3. Over the next 6-12 months, expect to see more cities adopt advanced surveillance and AI tools, driven by private funding, as they seek to improve safety and address staffing shortages without resorting to ineffective, broad-stroke policies.
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December 18, 2025

Two Futures | Runtime 2025

a16z

AI
Key Takeaways:
  1. Strategic Implication: The next decade will be defined by who builds the core infrastructure for intelligence. This is where the most significant value and influence will accrue.
  2. Builder/Investor Note: Direct capital and talent towards foundational AI components—chips, models, and interoperable systems. Avoid the temptation to only build at the application layer.
  3. The So What?: The window for shaping the future of intelligence is now. Engage in the deepest, most complex challenges to secure a footprint in this new era.
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December 18, 2025

The EU and the not-so-simple macroeconomics of AI – Luis Garicano

Epoch AI

AI
Key Takeaways:
  1. Strategic Implication: The global AI race is a zero-sum game for foundational models. Europe's best strategy is a "smart second mover" approach, focusing on the implementation layer by ensuring interoperability and data portability.
  2. Builder/Investor Note: Invest in AI that achieves true autonomy and enhances expert productivity. Be wary of markets stifled by over-regulation, which can impede AI adoption and growth.
  3. The "So What?": Europe faces a critical juncture. Without embracing AI-driven growth, its demographic and debt problems will worsen, leading to higher interest rates without the corresponding economic expansion.
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Crypto Podcasts

December 30, 2025

What's Next For Crypto In 2026 | Kairos Research

Lightspeed

Crypto
Key Takeaways:
  1. The migration from subsidized security to fee-based sustainability. Capital is fleeing "fake money" inflation for real yield.
  2. Monitor Solana's BAM plugins for maker prioritization. This allows perps to offer tighter spreads than centralized exchanges.
  3. 2026 is the year of the "Real" app. The winners will be those who stop hoarding interest and start sharing it with their users.
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December 30, 2025

Landmark Regulation, ICOs, Downtober & Privacy: 2025 Crypto Year in Review (Part 2)

Unchained

Crypto
Key Takeaways:
  1. The Macro Shift: Regulatory moats are being built around stablecoins to protect bank deposits. This forces a migration toward "consortium" models like Stripe’s Tempo.
  2. The Tactical Edge: Audit market maker agreements to ensure protection against exchange API failures. Reliability is now a competitive advantage.
  3. 2026 looks like a liquidity-driven recovery. The "easy road" is over, but the infrastructure for the next cycle is finally being built by adults.
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December 29, 2025

HIP-3 and Markets by Kinetiq with Omnia | Livestream

0xResearch

Crypto
Key Takeaways:
  1. The Macro Trend: Vertical Integration. Protocols are moving from single-utility tools to full-stack financial ecosystems that own both the liquidity and the application layer.
  2. The Tactical Edge: Monitor HIP-3 auctions. Watch how new exchanges utilize Kinetic's infrastructure to bootstrap liquidity without issuing predatory new tokens.
  3. The Bottom Line: Kinetic is building the infrastructure for a post-Binance world where users own the venues they trade on. This matters for your roadmap because user-owned liquidity is the next major phase of DeFi growth.
See full notes
December 29, 2025

Investing Trends for 2026: DeFi, Tokenization, Capital Formation, Speculation & AI

Bankless

Crypto
Key Takeaways:
  1. The move from human-centric trading to an agent-led economy where programmable money is the native substrate.
  2. Prioritize startups building verticalized tokenization for high-yield exogenous assets rather than generalized service providers.
  3. Crypto is becoming the invisible backend for global finance. Over the next year, the winners will be those who hide the blockchain while using its efficiency to crush traditional margins.
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December 28, 2025

Getting To The Bottom Of Quantum w/ Rearden

The Gwart Show

Crypto
Key Takeaways:
  1. The Macro Transition: Cryptographic security is moving from static models to active systems that must anticipate both classical and quantum breakthroughs.
  2. The Tactical Edge: Audit your UTXOs to ensure no address reuse and keep your Xpubs strictly offline.
  3. The Bottom Line: Quantum risk is a long tail event that serves as a catalyst for necessary Bitcoin upgrades like OP_CAT and BIP 360.
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December 28, 2025

Getting To The Bottom Of Quantum w/ Rearden

The Gwart Show

Crypto
Key Takeaways:
  1. The Macro Shift: Technical reality is decoupled from venture capital hype.
  2. The Tactical Edge: Use hashed addresses and run a node.
  3. The Bottom Line: Quantum is an engineering hurdle rather than an existential crisis for the next decade.
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