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AI Podcasts

May 29, 2025

Beyond Leaderboards: LMArena’s Mission to Make AI Reliable

a16z

AI
Key Takeaways:
  1. Reliability Demands Real-Time, Human-Centric Testing: Static benchmarks are dead. AI reliability for complex tasks requires continuous evaluation based on diverse, subjective human preferences in real-world scenarios.
  2. Crowd-Sourced Evaluation Outperforms Insular Expertise: The "wisdom of the crowd," as captured by LMArena, provides a more robust and representative measure of AI performance than siloed expert opinions, preventing narrow value-encoding.
  3. Personalized Evaluation is the Next Frontier: Technologies like "Prompt to Leaderboard" show the potential for highly granular, cost-effective, and personalized AI model selection, maximizing utility for individual users and specific tasks.
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May 28, 2025

Rick Rubin: Vibe Coding is the Punk Rock of Software

a16z

AI
Key Takeaways:
  1. Embrace AI as a Co-Creator: Leverage AI to democratize creation and rapidly iterate, but remember the unique human element—your distinct point of view and intuition—is irreplaceable.
  2. Authenticity Over Algorithm: Whether you're an artist or an entrepreneur, genuine connection comes from unwavering commitment to your core vision, not by chasing fleeting trends or assumed audience desires.
  3. Question Everything, Especially "Answers": Cultivate a mindset of curiosity and critical thinking. AI can provide answers, but true insight comes from deeply engaging with questions and understanding that knowledge is ever-evolving.
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May 27, 2025

7 More Healthy Years: What We Can Learn from Super Agers

a16z

AI
Key Takeaways:
  1. Embrace AI-Powered Prevention: AI's capacity to synthesize vast health data will redefine personalized risk assessment and early intervention, moving us beyond one-size-fits-all healthcare.
  2. Target the "Big Three" Early: Focus on preventing cancer, cardiovascular disease, and neurodegenerative conditions by leveraging their long incubation periods for proactive interventions.
  3. Leverage New Therapeutic Frontiers: Groundbreaking drug classes like GLP-1s and rapid advancements in immunotherapy offer unprecedented tools to combat and, crucially, prevent major diseases.
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May 27, 2025

TAOFU's Mikel & Mitch: Enabling Capital Formation for Subnets on Bittensors $10B+ Network

Delphi Digital

AI
Key Takeaways:
  1. Democratized Subnet Funding: TAOFU’s SNS model allows subnet creators to raise capital without diluting their core emission-earning potential, fostering more shots on goal for AI innovation on Bittensor.
  2. Investor Access & Liquidity: For investors, TAOFU provides a clear mechanism (SNS tokens and an integrated DEX) to invest in early-stage Bittensor subnets and gain liquidity, previously a closed-off and opaque process.
  3. Curated Quality: TAOFU’s permissioned approach and focus on sustainable value capture (with plans for a curator model) aim to filter for high-quality projects, protecting investors while nurturing promising AI ventures within Bittensor.
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May 26, 2025

Has AI Revived the DePIN Sector? | Dmitriy Berenzon

0xResearch

AI
Key Takeaways:
  1. AI is DePIN's Demand Catalyst: The need for affordable AI compute is breathing new life and tangible demand into decentralized infrastructure.
  2. Value Accrual & Revenue are King: For DePIN tokens to thrive in liquid markets, clear mechanisms for value flow-through from opco revenue to the token are non-negotiable; "ARR is the new TVL."
  3. Distribution Trumps Decentralization (for now): Crypto-native solutions, especially in payments, must crack the distribution code or risk being outmaneuvered by Web2 incumbents leveraging their massive user bases.
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May 26, 2025

Chatbot platforms might replace social media

Machine Learning Street Talk

AI
Key Takeaways:
  1. AI Companionship is Exploding: Millions are already deeply engaged with AI for emotional connection, and this is just the beginning as technology like GPT-4o normalizes it.
  2. Lean Engineering Can Win: Chai's success with a tiny, hyper-talented team and innovative techniques like model blending proves that massive VC-backed operations aren't the only path to scale in AI.
  3. The Next Social Platform Might Be AI: As AI offers more active, personalized, and consequence-free social interaction, it could very well become the dominant way people connect, potentially supplanting traditional social media.
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May 25, 2025

How Endless Debt Became America's Culture

Forward Guidance

AI
Key Takeaways:
  1. **Debt is Destiny:** America's fiscal irresponsibility and cultural embrace of debt ensure ongoing money printing and inflation, making currency debasement a near certainty.
  2. **The One True Trade:** Forget complex analytics; the primary goal is preserving purchasing power. This means owning store-of-value assets like Bitcoin and gold, which are positioned to thrive.
  3. **AI Accelerates the Crisis:** Artificial intelligence will not only disrupt labor markets but also intensify the debt crisis by devaluing traditional education and fueling calls for more government relief.
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May 24, 2025

SN85 :: VIDAIO :: Decentralized AI Video Upscaling & Compression ++ Roadmap & Enterprise Utility

Opentensor Foundation

AI
Key Takeaways:
  1. Decentralized AI is Production-Ready: VIDAIO demonstrates that complex AI tasks like video processing can be effectively decentralized and optimized through BitTensor's subnet model, with miners already outperforming base models.
  2. Perceptual Quality Wins: Focusing on human-perceived video quality, rather than just raw specs, is key for AI video tools, leading to more efficient and visually appealing results.
  3. Subnets Must Aim for Self-Sufficiency: The long-term viability of BitTensor subnets hinges on generating real-world revenue and solving actual customer problems, moving beyond reliance on token emissions.
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May 24, 2025

Sovereign AI: Why Nations Are Building Their Own Models

a16z

AI
Key Takeaways:
  1. National AI is Non-Negotiable: Countries are investing heavily in "AI factories" to control their digital destiny and cultural narratives.
  2. Models are Culture: AI outputs reflect embedded values, making local control over AI development and deployment a geopolitical imperative.
  3. Lead by Building Better: The US can maintain AI leadership by out-innovating competitors and enabling allies, pursuing "foundation model diplomacy" to ensure its technology underpins global progress.
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Crypto Podcasts

January 6, 2026

Markets React to U.S. Capture of Maduro

Unchained

Crypto
Key Takeaways:
  1. Production for Security. As globalization fractures, the US is trading ESG idealism for hard-asset reality.
  2. Buy Energy Infrastructure. Focus on SMR nuclear and solar companies that bypass traditional regulatory bottlenecks.
  3. Dollarized tech. This secures the energy needed for the AI and crypto buildout over the next decade.
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January 5, 2026

Bitcoin’s Back, Venezuela Regime Change, Memecoins, 2026 Mega Trends

1000x Podcast

Crypto
Key Takeaways:
  1. The Macro Transition: Geopolitical realignment is turning Bitcoin from a speculative asset into a tool of statecraft.
  2. The Tactical Edge: Buy Bitcoin calls dated for late January to capture the $125k target.
  3. The Bottom Line: The next six months will reward those who recognize that the "printing money" era has evolved into a "seizing assets" era.
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January 5, 2026

Inside SharpLink's Massive Ethereum Bet With CEO Joseph Chalom

The Rollup

Crypto
Key Takeaways:
  1. The migration from "Crypto" to "Digital Finance" where the underlying tech becomes invisible.
  2. Audit your protocol's risk disclosures. Prioritize security and third-party code reviews to attract institutional capital.
  3. Ethereum is the leading candidate for the world's financial operating system because it has ten years of zero downtime and a massive validator base.
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January 5, 2026

How the Stablecoin Milkshake will Redollarize the World

Bankless

Crypto
Key Takeaways:
  1. The US is moving from "analog" dollar dominance to a high-velocity digital network that absorbs global liquidity faster than ever.
  2. Maintain exposure to US equities and gold while keeping dollar-denominated cash in short-term bonds to capitalize on the next volatility spike.
  3. The dollar isn't dying; it is being upgraded. Expect the "Milkshake" to suck up global capital as foreign economies struggle with debt and declining growth.
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January 3, 2026

Predictions for 2026

Bell Curve

Crypto
Key Takeaways:
  1. The movement from casino to utility means capital will flow toward protocols with high revenue quality and durability.
  2. Prioritize DeFi products that bridge institutional assets to retail front-ends.
  3. 2026 is the year crypto stops being a promise and starts being a product.
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January 2, 2026

Crypto Only Has 2 Real Business Models | Ejaaz Ahamadeen

The DCo Podcast

Crypto
Key Takeaways:
  1. Value is migrating from raw infrastructure to the model layer. As compute becomes a commodity, the economic winner is the entity that owns the weights and the inference interface.
  2. Audit your portfolio for projects with Visa-style fee structures. Prioritize protocols that generate revenue from external usage rather than internal token circularity.
  3. Sustainable crypto AI requires moving past speculative emissions toward actual service fees. The next year will separate apps that use AI to solve problems from protocols that use AI to sell tokens.
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